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METHODS AND SYSTEMS FOR DESIGNING DENTAL APPLIANCES FOR DIRECT FABRICATION

Resumen de: US20260336220A1

Methods and systems for designing dental appliances are provided. In some embodiments, a method includes: receiving a digital representation of an appliance geometry for a dental appliance configured to be worn on a patient's teeth; predicting a change in a size of a portion of the dental appliance when the dental appliance is fabricated via an additive manufacturing process; adjusting the appliance geometry of the dental appliance to compensate for the predicted change in size; and generating instructions for fabricating the dental appliance based on the adjusted appliance geometry.

Print Head and Cartridge for an Additive Manufacturing Device for Forming a Drug Delivery Device

Resumen de: US20260335191A1

Print head assembly for an additive manufacturing device for forming a drug delivery device, the print head assembly comprising:—a print head, comprising a print head housing with a receptacle for receiving at least part of a cartridge therein; and—a cartridge having an internal volume for holding a volume of drug delivery material; wherein the cartridge is provided with a level indicator providing a level signal indicative of a level of drug delivery material inside the internal volume, and wherein the print head is provided with a level signal sensor arranged for receiving the level signal of the level indicator of the cartridge.

METHODS AND SYSTEMS OF FACILITATING A HEALTH ASSESSMENT

Resumen de: US20260341513A1

The present disclosure provides a method of facilitating a health assessment. Further, the method may include receiving a medical inquiry. Further, the medical inquiry may be generated by a user. Further, the method may include analyzing the medical inquiry. Further, the method may include generating an assessment query based on the analyzing. Further, the generation of the assessment query may be based on one or more of a template and a first machine learning model. Further, the template includes a standardized assessment query. Further, the method may include transmitting the assessment query. Further, the method may include receiving a response from the healthcare communication infrastructure. Further, the response corresponds. Further, the method may include analyzing the response. Further, the method may include determining a diagnosis data based on the analyzing. Further, the method may include transmitting the diagnosis data.

INTELLIGENT INFUSION BASED ON ANTICIPATING PROCEDURAL EVENTS

Resumen de: US20260334872A1

0000 An intelligent control device provides an option to select a medical procedure and receives a selection of the medical procedure. The intelligent control device also operates an infusion device to administer a medication at a first rate. Further, the intelligent control device identifies a set of events associated with the selected medical procedure, including a procedural event expected to cause a physiological change for which an administration of the medication is prescribed. Moreover, the intelligent control device determines that the procedural event is about to occur based on the infusion information, the physiological information, or the selected medical procedure. After determining that the procedural event is about to occur, and before the procedural event occurs, the intelligent control device prompts an operator to cause an adjustment of the infusion device to administer the medication at a second rate; or the intelligent control device causes the adjustment of the infusion device.

TECHNOLOGY FOR INEXPENSIVE AND QUANTIFIED ASSESSMENT OF INFANT SUCKLING BEHAVIOR

Resumen de: US20260334811A1

Provided herein is a method for evaluating infant suckling behavior, comprising: collecting suckling data from an infant using a vacuum measurement device, transmitting the collected suckling data to a processor, processing the collected suckling data by the processor using a pre-trained Machine Learning (ML) algorithm to identify one or more abnormalities in the infant's suckling behavior, wherein the ML algorithm has been trained on a set of training data comprising a plurality of dimensions associated with the training data, and wherein the identified one or more abnormalities are corresponding to one or more of the plurality of dimensions.

BIOMATERIAL-INK FOR 3D PRINTING

Resumen de: US20260335503A1

Three-dimensional (3D) bioprinting has tremendous potential to aid in the creation of engineered tissues and organs that are so desperately in need. In this disclosure, a new type of bio-ink for 3D bioprinting made of sheared slurries of biomaterial hydrogel, in particular alginate hydrogel having micro-capillary structure (Capgel), in particular Capgel having increased stackability and thus self-assembly capability through the formation of a polyelectrolyte complex “skin” on the outer surfaces of the Capgel block with poly-L-lysine (PLL) coating prior to printing needle extrusion is provided as injectable biomaterial tissue scaffolding system, so that such stackable structure as weave patterns and cylindrical structures can be successfully printed with the new Capgel bio-ink. Further, the micro-capillary structure inherent in the original Capgel blocks is retained in the printed bio-ink making up the larger 3D structures and allows for cell culture in it.

APPARATUS AND METHODS FOR USE WITH IMAGE-GUIDED SKELETAL PROCEDURES

Resumen de: US20260335013A1

0000 A tool (538) is advanced along an insertion path (542) into a skeletal portion within a body of a subject. 3D image data of the skeletal portion is acquired using a 3D imaging device. The tool is positioned at a location along the insertion path and a 2D x-ray of the at least a portion of the tool and the skeletal portion is acquired using a 2D x-ray imaging device. Using at least one computer processor (22), the single 2D x-ray is registered to the 3D image data. The computer processor reconstructs a 3D location of the tool with respect to the skeletal portion based on the at least a portion of the tool in the single 2D x-ray that is registered to the 3D image data, and generates an output, at least partially in response thereto. Other applications are also described.

Methods and interfaces for providing donation process feedback

Resumen de: AU2026253875A1

27106278_1 (GHMatters) P127225.AU.1 A method includes detecting a beginning of a donation process; in response to detecting the beginning of the donation process, providing an output; determining an amount of time remaining for the donation process; in response to detecting the amount of time remaining for the donation process, updating the output; detecting a loss in pressure; in response to detecting the loss in 5 pressure, updating the output; detecting an ending of the donation process; and in response to detecting the ending of the donation process, updating the output. The donation process may include a plasma donation using an apheresis machine. The detecting the beginning of the donation process may include detecting a flow of fluid. The output may include one or more of a light and a sound. The output may be provided on a side of an apheresis machine. 10 ct c t

CELL MACROENCAPSULATION DEVICES, METHOD OF FABRICATION AND USE THEREOF

Resumen de: US20260337551A1

It is provided a cell macroencapsulation device for implanting cells in a recipient comprising cells encapsulated in a porous membrane, wherein the porous membrane consists of a sugar network coated with a polymeric solution comprising porogen, which can be used as a graft to transplant islets while protecting the graft from the immune system as well as providing enhanced convection and diffusion to ensure long-term cell survival and physiological insulin delivery.

ROBOTIC ENCODING SYSTEM AND METHOD

Resumen de: US20260336889A1

0000 A lockable container encoding system and method is disclosed. The lockable container encoding system is for use in the manufacture of encodable lockable containers, wherein the encodable lockable container comprises an annular sidewall having a plurality of annular rings, the annular rings having an inner and outer surface, the inner surface featuring a plurality of selectable removable tabs for the encoding of lockable containers. The lockable container encoding system includes a tumbler for receiving unencoded encodable lockable containers, a receptor having a sidewall dimensioned and configured to hold a plurality of encodable lockable containers, a first articulating arm comprising a plurality of ring manipulators, a vision system in communication with the ring manipulators to monitor the physical position of the plurality of annular rings of the encodable lockable container, and a second articulating arm comprising a plunger having a shearing blade; wherein the shearing blade comprises guide rails couplable to the shearing blade, wherein the shearing blade removes a plurality of selected removable tabs from an unencoded lockable container to encode the container.

PERSONALIZED PERITONEAL DIALYSIS TREATMENT USING DESIGN OF EXPERIMENT TECHNIQUES

Resumen de: US20260335519A1

0000 The described technology generally includes systems and processes for a PD optimization process may operate to estimate, predict, or otherwise determine the value of PD dose variables values based on patient characteristics and/or PD prescription information. In one embodiment, a PD optimization process may be or may include a UFV determination process, operative to determine a predicted UFV for a patient. In some embodiments, the UFV determination process may include training a computational model to generate a predicted UFV output based on input of patient characteristics, PD prescription information, PD outcomes (for instance, UFV), and/or historical information associated with patient characteristics, PD prescription information, and/or PD outcomes. In some embodiments, a feedback control process with continuous Intraperitoneal Pressure (IPP) and hydration status measurements may be used to keep the hydration status of the patient within a target level ran. Other embodiments are described.

RELAPSE PREVENTION RETAINER

Resumen de: US20260335046A1

Apparatuses and methods for customized retainers to prevent relapse. In particular, described herein are customized retainers, and methods and apparatuses for making customized retainers that specifically reenforce and prevent movement of one or more teeth having a higher likelihood of relapse following completion of an orthodontic treatment plan.

THERANOSTIC DEVICE FOR CANCER IMMUNOTHERAPY

Resumen de: US20260337578A1

Provided herein compositions and methods including bioprinted tissue fibers comprising precisely patterned cancerous and non-cancerous cells that are capable of recapitulating a desired tumor microenvironment in vitro. The subject tissue models enable the automated high throughput screening of anti-cancer therapies in a biologically-relevant human system, and can be further personalized with patient-specific cells.

Modellplatte für Artikulatoren

Resumen de: DE102025139221A1

Die vorliegende Erfindung betrifft eine Modellplatte (14, 15) für Artikulatoren (1), welche ausgebildet ist, einen Teil eines Kiefermodells (16, 17) mit dem Artikulator (1) feststehend und zerstörungsfrei lösbar zu verbinden, mit einer Mehrzahl von Stegen (14b, 15b), welche eine Mehrzahl von Öffnungen (14c, 15c) bilden, wobei die Modellplatte (14, 15) mittels einer badbasierten Photopolymerisation hergestellt ist. Die Modellplatte (14, 15) ist dadurch gekennzeichnet, dass zumindest einige der Öffnungen (14c, 15c), vorzugsweise alle Öffnungen (14c, 15c), durch Verbindungskanäle (14d, 15d) miteinander und/oder durch Verbindungskanäle (14d, 15d) mit der Umgebung der Modellplatte (14, 15) verbunden sind.

CUSTOMIZED PATIENT-SPECIFIC 3D PRINTED POSITIONING AUGMENT FOR ORTHOPAEDIC SURGICAL IMPLANT

Resumen de: US20260335093A1

An orthopaedic prosthetic component includes a manufactured acetabular shell component having an outer wall and an additively manufactured augment coupled to the outer wall. The augment includes an outer surface that defines a customized patient-specific negative contour shaped to conform to a positive contour of a patient's bone. A method for manufacturing the prosthetic component is also disclosed.

Cloud Based System Cataract Treatment Database and Algorithm System

Resumen de: US20260335030A1

Systems, devices and methods are provided that provide assistance in selecting appropriate interventions for treatment of disease and injury to the eye. Systems of the inventive concept provide cloud-based processing and storage of clinical and patient-specific data, which can provide treatment recommendations and projected outcomes to a practitioner using a local device. Systems, devices, and methods can generate interactive physiomechanical models of the eye of a specified individual, which are derived measurements of mechanical properties of structures of the eye. The physiomechanical model is interactive, and can be used to emulate the effects of one or more medical interventions in the eye in order to implement an optimized treatment plan for the individual.

Confidence Indications Derived From Plural Strings

Resumen de: US20260341401A1

0000 Disclosed are systems comprising an analyzing unit comprising a) a receiver configured to receive a plurality of sequencing reads from a sample, the plurality of sequencing reads comprising at least one genetic variation undetectable within a sequencing system error rate; b) a noise processing filter configured to: i) reduce signal noise from the plurality of sequencing reads; ii) calculate a confidence indication based on a determination from at least one sequencing read of the plurality of sequencing reads; and iii) calculate a corrected confidence indication based on a comparison of the determinations from at least two sequencing reads, each drawn from the plurality of sequencing reads. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

APPARATUS AND METHOD FOR SUBJECT MONITORING AND DIAGNOSING WITH NON-INVASIVE MEASURES

Resumen de: US20260334885A1

An apparatus and method for subject monitoring and diagnosing with non-invasive measures are disclosed. The apparatus includes a memory contains instructions configuring at least a processor to receive non-invasive measurement data associated with a subject, wherein the non-invasive measurement data comprises electrocardiogram (ECG) data received from an ECG machine and echocardiogram (echo) data received from an echocardiogram device, and extract at least an ECG feature of the ECG data and at least an echo feature of the echo data, generate a synthetic computed tomography (CT) image of the subject as a function of the fused non-invasive measurement datum, wherein the synthetic CT image is generated without using CT imaging data or magnetic resonance imaging (MRI) imaging data of the subject as an input, and transmit the synthetic CT image to a remote device.

SYSTEMS AND METHODS FOR IMPLEMENTING AN INDIVIDUALIZED DRUG DELIVERY PROFILE FOR A RECIPIENT OF A COCHLEAR IMPLANT SYSTEM

Resumen de: US20260341452A1

An exemplary system comprises a memory that stores instructions and a processor communicatively coupled to the memory and configured to execute the instructions to perform a process. The process may comprise generating, based on a recipient-specific anatomical structure of a cochlea of a recipient of a cochlear implant system and historical procedure data associated with one or more previously performed lead insertion procedures, an individualized drug delivery profile for the recipient; and controlling, in accordance with the individualized drug delivery profile for the recipient, a release of a drug from a stimulating portion of a stimulating lead within the recipient based on a command transmitted to a cochlear implant that includes the stimulating lead.

SYSTEM FOR CRANIOMAXILLOFACIAL AND ORTHOPAEDIC RECONSTRUCTION

Resumen de: WO2026224693A1

The present disclosure relates to a composition, a method for preparing the composition, and a system for implementing the composition for craniomaxillofacial and orthopaedic reconstruction. The composition comprises silk fibroin microfibres; a polymer matrix including polycaprolactone (PCL), and poly(lactide-co-glycolide) (PLGA) or poly(L- lactide-co-D, L-lactide) (PLDLA); a calcium phosphate ceramic phase comprising hydroxyapatite (HA), tricalcium phosphate (TCP), biphasic calcium phosphate (BCP), borate glass, bioactive glass; and a bioactive agent. The method for preparing the composition comprises the steps of raw silk processing, preparation of the composite filament, 3D printing and injection moulding of composite filament to obtain bone scaffolds, screws and plates. The system comprises a material processing assembly, a filament extrusion unit, a 3D printing apparatus, a moulding apparatus and a control unit. The said composition is intended for fabrication into craniomaxillofacial reconstruction plates, resorbable screws, interference screws, meshes, grafts, segmental defect scaffolds, and orthopaedic load-sharing implants.

APPARATUS AND METHOD FOR CONTROLLING A ROBOTIC FRAMEWORK TO PERFORM IMAGING MODALITIES

Resumen de: US20260334912A1

An apparatus and method for controlling a robotic framework to perform imaging modalities. The apparatus includes at least a processor and a memory communicatively connected to the at least a processor. The memory instructs the processor to receive a target region, receive, from a localization system, the at least a position signal of the catheter, generate, using at least a reinforcement-learning model, a movement vector as a function of the at least a position signal, control, using the at least a processor, the robotic framework, as a function of the movement vector, and generate, as a function of the plurality of ultrasonic signals, a three-dimensional (3D) model of the target region.

SYSTEM, LOCATION TAG ASSEMBLY AND PATIENT SUPPORT APPARATUS FOR LOCATING MOBILE TAGS IN REAL-TIME IN A MEDICAL FACILITY

Resumen de: US20260341496A1

0000 There is provided a system, a patient support apparatus, and a location tag assembly for locating mobile tags in real-time in a medical facility using a plurality of wireless signal modalities where the tags could be worn by patients or attached to equipment. The location tag assembly can be secured to a patient support apparatus which could be located precisely with respect to a wireless locating node. The wireless locating nodes may be used to locate a first type of mobile tag. The location tag assembly may be used to locate a second type of mobile tag. The location information may be transmitted to a server to precisely locate patient support apparatuses, medical equipment, patients and staff in real-time.

DYNAMIC ALLOCATION FOR MULTI-PUMP BOLUS VOLUMES

Resumen de: US20260335546A1

Certain aspects of the disclosure provide infusion systems and methods for generating an infusion plan for a set of infusion devices. For example, the method may include receiving an infusion order for a patient, determining the infusion order exceeds a bolus threshold, and identifying a set of infusion devices associated with the patient. The method may further include generating an infusion plan for the set of infusion devices based on the infusion order and adjusting one or more operational parameters of the set of infusion devices according to the infusion plan.

Snap-Off Hammertoe Device

Resumen de: US20260335096A1

A snap-off hammertoe device is disclosed, comprising a body component engaged with a shaft extension. The body component comprises a first end which engages the shaft extension and a second end with a penetrating tip. The shaft extension is a snap-off barrel component which is used to insert the hammertoe device and is broken off by means of torsion or bending torque after the body component is inserted. The snap-off barrel component or shaft extension and the body are both cannulated, such that a guidewire can be inserted. Further, the snap-off barrel component or shaft extension and the body are additively manufactured and grown as a single part.

MICROMECHANICAL RESONATORS

Nº publicación: WO2026224669A1 29/10/2026

Solicitante:

NORTHERN DIGITAL INC [CA]
VOGTMEIER GEREON [NL]
GLEICH BERNHARD [DE]
MAZURKEWITZ PETER CAESAR [DE]
SCHILLING CHRISTIAN JOERG [CH]
NORTHERN DIGITAL INC.
VOGTMEIER, Gereon
GLEICH, Bernhard
MAZURKEWITZ, Peter C\u00E4sar
SCHILLING, Christian J\u00F6rg

Resumen de: WO2026224669A1

A device (e.g., a micromechanical resonator) can include an elongated housing having a first end, a second end, and a sidewall extending from the first end to the second end. A longitudinal opening can extend through the sidewall and extend from an axial center at the first end to the second end. The device can include a filament with a first end of the filament attached to the first end at the axial center. The device can include a first magnetic object with a second end of the filament attached to the first magnetic object. The device can include a second magnetic object and being spaced apart from the first magnet. The filament is configured to allow the first magnetic object to oscillate about a longitudinal axis of the elongated housing relative to the second magnetic object in response to a magnetic or electromagnetic field.