Alerta

SYSTEMS AND METHODS OF MONITORING WEAR COMPLIANCE OF A PATIENT WEARING AN AMBULATORY MEDICAL DEVICE

Resumen de: EP4792873A2

0001 Devices, systems, and methods for providing patient wear compliance information are provided. For example, a medical device includes a plurality of electrodes configured to be continuously coupled externally to a patient and to monitor electrical activity on the skin of the patient. The system also includes at least one motion sensor configured to generate a motion signal based upon movement of the patient. The system further includes a processor configured to receive an electrical signal based on the monitored electrical activity, record a wear onset event based on the electrical signal and the motion signal, record a wear offset event based on one or more of the electrical signal and the motion signal indicating that the patient is not wearing the medical device, and output a graphical representation including information regarding the patient's wear compliance based on the recorded wear onset event and the recorded wear offset event.

IMAGING DEVICE AND METHOD FOR DETECTING A SEAM AREA BETWEEN MEDICATION SACHETS

Resumen de: EP4793635A1

0001 The present invention relates to an imaging device (100) that comprises a first polarizer (101) and a second polarizer (102) between which a strip (200) of medication sachets can be arranged, a camera (103) for imaging a first side of the strip (200) of medication sachets through the second polarizer (102), and means (104) for changing the polarization direction of the first polarizer (101) or the second polarizer (102). The present invention also relates to a method for detecting a seam area (203) between medication sachets (201, 202) and to a medication dispenser (300).

一种基于3D打印技术的牙齿修复体加工装置及方法

Resumen de: CN122584671A

本发明涉及牙齿修复体3D打印技术领域，具体为一种基于3D打印技术的牙齿修复体加工装置及方法，包括支撑台，还包括：驱动机构，其安装在支撑台上，且升降端上安装升降板；震动机构，其安装在升降板上；晃动机构，其安装在支撑台上，且用于晃动树脂材料；震动机构包括支撑组件、阻尼组件、间隔组件、阻挡组件、承载组件和支撑板；支撑板安装在升降板上且随着升降板升降；支撑组件安装在支撑板上；承载组件安装在支撑组件底部且用于承载打印出的牙齿修复体；本发明使得弹性件一的弹性带动安装板快速上升震动，从而使得承载板底端的牙齿修复体震动，从而将牙齿修复体表面残留的树脂材料抖落，从而避免了树脂材料的残留和浪费。

一种鞍座高度标记确定方法、儿童平衡车以及调节方法

Resumen de: CN122590785A

0001 本申请涉及儿童平衡车技术领域，尤其是涉及一种鞍座高度标记确定方法、儿童平衡车以及调节方法，方法包括基于测试数据确定每个测试身高区间对应的初始理论鞍座高度；获取每个初始理论鞍座高度对应的静态测量数据，并确定多个静态指标和静态指标测量值；对异常理论鞍座高度进行微调，得到对应的修正鞍座高度；基于每个动态测量数据确定多个动态指标和动态指标测量值；将每个动态指标的动态指标测量值与对应的预设动态指标理论值区间相比，对异常修正鞍座高度进行微调，得到每个测试身高区间对应的目标鞍座高度。本申请便于提升不同身高区间的儿童与鞍座高度的匹配精准度，以匹配儿童身体发育特点、促进建立正确骑行姿态。

一种肠风黑散碳点方剂及其制备方法与应用

Resumen de: CN122582187A

本发明实施例公开了一种肠风黑散碳点方剂及其制备方法与应用，属于生物制药技术领域。一种肠风黑散碳点方剂的制备方法包括：取等质量的荆芥、枳壳、乱发、槐花、槐角、甘草、刺猬皮，将各单味药材依次经煅烧、粉碎、提取、过滤、浓缩、第一透析纯化后，定容至相同体积，得到单味碳点溶液；单味碳点溶液按体积比2：3：1：1：1：1.5：1.5混合，经超声、第二透析纯化，得到所述肠风黑散碳点方剂。本发明提供的肠风黑散碳点方剂可靶向聚集于烧伤受损肠道组织，对烧伤后肠黏膜损伤表现出突出的修复、保护效果，具备较好的临床应用转化前景。

融合器和3D打印融合器

Resumen de: CN122581941A

本申请公开了一种融合器和3D打印融合器，融合器本体、至少一个骨螺钉和限位件，融合器本体沿第一方向的一侧开设有至少一个安装孔和至少一个螺钉孔，融合器本体用于植入脊柱，使融合器本体沿第二方向的至少一侧与脊柱接触；骨螺钉用于穿过螺钉孔，并植入融合器本体沿第二方向一侧的脊柱；限位件包括相互连接的限位部和连接部，连接部安装于安装孔，限位部用于与至少一个骨螺钉抵接，以限制至少一个骨螺钉脱出螺钉孔；连接部设有卡接部，卡接部与融合器本体卡接，以限制连接部脱出安装孔。由此，能够使连接部与融合器本体的连接更加稳定、方便，限位件与融合器本体之间不会出现压铆力过大或过小，而影响限位件与融合器本体之间的连接稳定性。

処理装置、プログラムおよび処理システム

Resumen de: JP7906978B1

【課題】呼吸治療装置を使用する患者の状態を把握しやすくすることを目的とする。【解決手段】処理装置１００は、加湿機能を備え、患者に空気を送出する呼吸治療装置３００から、前記空気のリーク量を示す情報、および前記加湿機能による前記空気への加湿の強さを示す情報を取得する取得部１０１，１０５と、所定期間毎の前記リーク量、および前記所定期間毎の前記加湿の強さを同一の時間軸上に表示させるデータを生成する処理部１０１と、を備える。【選択図】図５

以患者状态为基础设定诊疗顺序的运算装置及其控制方法

Resumen de: KR20250113351A

The present disclosure provides a method and a computing device for setting a treatment order based on a condition of an emergency patient. According to an embodiment of the present disclosure, a method for setting a treatment order based on a state of an emergency patient, which is performed by a computing device including at least one processor, comprises the steps of: acquiring biometric data of a new examination subject through a sensing unit when reception data of the new examination subject is acquired; analyzing the biometric data using a pre-learned neural network model to identify the state of the new examination subject; and setting a treatment order of the new examination subject based on a time at which the reception data of the new examination subject is acquired and the state of the new examination subject, wherein the step of setting the treatment order includes a step of setting the treatment order of the new examination subject by adjusting the treatment order of other examination subjects previously received and waiting for treatment based on the state of the examination subject.

具有用户评估和误差校正的血压传感器系统

Resumen de: WO2025147689A1

Systems and methods are disclosed for reducing error in the measurement of a user's blood pressure with a physiological monitoring device that includes a sensor assembly with a PPG module and a pressure sensor module. Exemplary methods include the steps of placing a finger on the physiological monitoring device such that the finger is in contact with the sensor assembly, instructing the user to apply a range of pressures to the pressure sensor module during a measurement cycle, creating a measured oscillometric curve based on the PPG data and pressure sensor data retrieved during the measurement cycle, and determining whether the measured oscillometric curve is based on unreliable or incorrect data before calculating the user's blood pressure from the measured oscillometric curve.

Apparatus and method for localization associated with aortic valve repair using transesophageal echocardiography

Resumen de: US12708457B1

An apparatus for localization associated with aortic valve repair using transesophageal echocardiography, wherein the apparatus includes a probe configured to capture images of an aortic valve pertaining to a subject, a delivery system including a delivery catheter configured for aortic valve repair, and a computing device configured to receive a 3D model representative of the aortic valve, receive an initial set of images from the Probe, wherein the Probe is located within an esophagus of the subject, identify a position of the Probe and the delivery system by identifying anatomical landmarks within the initial set of images and locating the position of the Probe and the delivery system relative to the anatomical landmarks and display the position of the delivery system relative to the 3D model.

신속 붕해 정제를 위한 개질 전분 기반 재료

Resumen de: WO2025124741A1

The instant invention relates to a powder layer for use in 3D binder jetting printing comprising a hydrolyzed and functionalized starch compound. It also relates to a process for 3D binder jetting printing using the same. It also relates to products, in particular solid dosage forms, obtained thereof by 3D binder jetting printing.

추적 마커 기반 표적 약물 전달을 위한 경구용 약물 제형 및 이의 설계 및 사용 방법

Resumen de: WO2025124483A1

Provided is an oral drug dosage form configured to be used for targeted drug delivery at a desired gastrointestinal location, methods of design and use related to the oral drug dosage form.

一种上颌第一磨牙拔除术前规划方法及系统

Resumen de: CN122598951A

0001 本申请提供一种上颌第一磨牙拔除术前规划方法及系统；所述上颌第一磨牙拔除术前规划方法包括：基于患者的CBCT数据和口扫数据构建患牙三维模型；基于所述患牙三维模型获得最优分牙深度；根据所述CBCT数据构建有限元模型，以基于所述有限元模型获得拔牙器械的最优用力方向；根据所述患牙三维模型获得各牙块的最优脱位方向；以及，结合所述最优分牙深度、最优用力方向和最优脱位方向评估术中风险等级，以生成风险评估和规划报告。本申请将数字化技术与拔牙手术的临床需求深度融合，显著提升了上颌第一磨牙，尤其是高难度病例拔除术前评估的精准性、预见性和安全性，有助于系统性降低手术并发症，提高手术成功率。

便携式无创血糖连续监测的医学检验设备及监测算法

Resumen de: CN122581750A

0001 本发明公开便携式无创血糖连续监测的医学检验设备及监测算法，涉及医学监测技术领域，算法通过物理信号采集层的量子点增强传感器与代谢共振激发器采集血糖相关物理信号，经量子信号处理层处理后，利用智能算法核心中包含时空图卷积模块、代谢动力学建模模块和个性化适配层的时空图卷积神经网络进行信号处理，输出血糖值和置信度，设备集成各关键组件，且有动态校准机制，算法核心将血糖值和置信度输出至校准决策模块，依据置信度判断是否触发校准微，流控系统配合组织液采集与电化学检测实现参数优化，整体设计为便携式结构，便于日常使用，实现精准无创血糖连续监测。

一种用于断奶仔猪肠道发育与功能的综合检测方法

Resumen de: CN122581676A

0001 本发明涉及畜牧养殖与智能检测技术领域，具体公开了一种用于断奶仔猪肠道发育与功能的综合检测方法，包括：采集断奶仔猪粪便与腹壁近红外光谱，融合DNA甲基化标记及近红外荧光纳米传感器，无创定位肠道微损伤区域；采集断奶仔猪不同日龄肠道内容物，构建代谢组时序图谱，融合自适应神经模糊推理系统，对已定位损伤进行急性或慢性病程回溯，区分应激性损伤与发育滞后；本发明通过融合粪便脱落细胞DNA甲基化检测与近红外荧光纳米传感器的腹壁透射光谱分析，无需采集肠道活检组织即可生成三维肠道损伤概率热力图，能够检出常规手段难以发现的早期隐袭性损伤，并可区分原发性损伤与继发性扩散区域，显著降低断奶仔猪肠道病变的漏检率。

基于脑电图自监督图结构提取的抑郁症表征提取方法

Resumen de: CN122599087A

本申请公开了基于脑电图自监督图结构提取的抑郁症表征提取方法，涉及脑电信号处理技术领域，方法包括：提取正常脑电图信号的原始信号、伪幅值异常信号和伪频率异常信号的单通道时序特征作为节点特征；提取正常脑电图信号的原始信号、伪弱连接信号和伪强连接信号的通道间关联特征作为边特征；根据节点特征和边特征构建脑功能网络图结构；利用多层池化提取脑功能网络图结构各层的图级表征；累加各层图级表征得到最终的图表征作为抑郁症表征。本申请通过生成脑电图信号的伪异常信号来构建脑功能网络图结构，进而提取图级特征，能够准确表示脑电图信号的特征，可为分析抑郁症提供真实准确的数据基础。

一种3D打印nHA/PCL-CSMA-Exos颌骨缺损修复材料及其制备方法

Resumen de: CN122582359A

本发明涉及生物医用材料技术领域，具体涉及一种3D打印nHA/PCL‑CSMA‑Exos颌骨缺损修复材料及其制备方法。本发明通过高温熔融沉积制备仿生多孔20%nHA/PCL支架，经紫外光交联CSMA构建生物活性界面，并基于静电作用负载骨髓间充质干细胞外泌体BMSC‑Exos，得到复合支架nHA/PCL‑CSMA‑Exos。该支架具有良好的亲水性、生物相容性，能够显著促进细胞增殖、细胞迁移，同时能够促进骨组织的生成。这种结合3D打印精准成型、水凝胶生物活性涂层和外泌体调控功能的复合支架，为口腔颌面部骨缺损的再生修复提供了兼具结构适配性、力学适配性和生物适配性的新型解决方案，具有重要的临床转化价值。

一种具有本征亲水表面的喷墨3D打印氧化锆陶瓷制品及其制备方法与应用

Resumen de: CN122586551A

本发明属于生物医用陶瓷材料技术领域，具体涉及一种具有本征亲水表面的喷墨3D打印氧化锆陶瓷制品及其制备方法与应用，本发明提供的喷墨3D打印氧化锆陶瓷制品的制备方法通过优化墨水组分、打印参数及脱脂烧结工艺，实现了氧化锆陶瓷的极端晶粒细化、微观应变引入及微量单斜相生成，从而获得高表面能和亲水特性，该制品在无需任何后续表面改性处理的情况下，即表现出优异的细胞相容性、免疫调节特性和软硬组织整合能力。

肝细胞来源外泌体辅助的3D生物打印皮肤类器官在创面再生上的应用

Resumen de: CN122587982A

本发明提供了肝细胞来源外泌体辅助的3D生物打印皮肤类器官在创面再生上的应用。该3D生物打印皮肤类器官支架，将角质形成细胞、成纤维细胞和内皮细胞包裹在含HC‑exos的GelMa‑ECM水凝胶中，模拟天然皮肤结构。添加HC‑exos后，该构建物发挥抗氧化、上调再生细胞过程和调控信号通路等重要作用，在创面愈合微环境中实现高效组织再生，为大面积全层皮肤损伤的治疗提供了有前景的方案。该构建物具有优异的生物相容性和有效性，在临床转化中具有广阔前景。

一种按摩设备的智能控制方法及装置

Resumen de: CN122582004A

本申请提供一种按摩设备的智能控制方法及装置，涉及智能控制技术领域。在本申请中，在按摩设备按照第一按摩模式对目标对象进行按摩的过程中，获取按摩设备在当前时刻作用于目标对象的原始压力信号；对原始压力信号进行第一次信号解耦，得到第一信号分量；基于第一信号分量指示的有效按摩压力，以及与当前时刻相邻的上一时刻的历史压力参考基线，确定当前时刻对应的当前压力参考基线；基于有效按摩压力与当前压力参考基线之间的压力差值，以及预设的压力差值范围，识别目标对象的按摩力度意图，确定按摩设备的目标按摩模式。这样，可以准确且自适应地调整按摩设备的按摩模式，以更好地满足用户的按摩需求。

一种桡骨远端骨折的3D打印个性化夹板

Resumen de: CN224639939U

本实用新型公开了一种桡骨远端骨折的3D打印个性化夹板，包括：背侧板、掌侧板、尺侧板和桡侧板，背侧板、掌侧板、尺侧板和桡侧板均为曲面形夹板，曲面的方向与桡骨形状契合；每个夹板的宽度从手腕向手肘方向逐渐增大；每个夹板的两侧均设置边缘减薄结构；每个夹板的上表面相应位置上设有多对加强筋，在每对加强筋上设有绑带限位卡扣，每对加强筋中的两加强筋之间且位于绑带限位卡扣的正下方处设有绑带下陷平台；背侧板对应位置设置有防尺侧压疮凹陷、防背侧碰撞凹陷和第一防桡侧压疮凹陷；掌侧板对应位置设置有防掌侧肌肉压迫切面；桡侧板对应位置设置有第二防桡侧压疮凹陷。本实用新型针对患者的个体化差异，制作出满足要求的个性化夹板。

一种聚乳酸类聚酯纳米片粉末及其制备方法与应用

Resumen de: CN122587245A

一种聚乳酸类聚酯纳米片粉末及其制备方法与应用，涉及高分子材料技术领域，解决了聚乳酸类聚酯粉末的制备技术难以兼顾工艺简洁、设备成本低、形貌可控及避免外源性杂质残留的问题。本发明通过将聚合物加入混合溶剂中，静置，得到聚合物凝胶；向聚合物凝胶中加入溶剂，搅拌得到悬浊液，将悬浊液过滤、干燥得到聚乳酸类聚酯纳米片粉末，可应用于药物缓释载体、医美组织填充材料、3D打印材料领域。本发明实现了聚乳酸类聚酯纳米片状结构的可控制备，显著减少了聚乳酸类聚酯纳米片粉末中单体残留率（0.10%～0.15%）和溶剂残留率（0.01%），进而大幅降低杂质残留风险。

魚肝臓の脱細胞化マトリックスによるマイクロ流体制御３Ｄプリントハイドロゲル及びその作製方法並びに応用

Resumen de: CN119367613A

The invention discloses a fish liver acellular matrix-based microfluidic 3D printing hydrogel for liver regeneration and a preparation method thereof, the fish liver acellular matrix (dECM) and gelatin methacryloyl (GelMA) are combined together, and induced pluripotent stem cell-derived hepatocytes (iPSC-hep) are loaded for liver regeneration. The microfluidic 3D printing hydrogel based on the fish liver acellular matrix has excellent biocompatibility, retains complete endogenous growth factors, retains the biological activity of cells, ensures effective cell encapsulation, and is beneficial to stable functional expression of iPSC-hep. After in-vivo transplantation, the survival rate and the liver function of acute hepatic failure mice are remarkably improved, and regeneration and repair of the liver are promoted.

METHOD AND DEVICE FOR GENERATING ECG SIGNAL

Resumen de: WO2026169117A1

The present disclosure relates to a method and a device for generating a digital electrocardiogram signal on the basis of an electrocardiogram record. According to an embodiment of the present disclosure, a method for generating a digital electrocardiogram signal on the basis of an electrocardiogram record is provided, the method including the steps of: performing preprocess to extract first electrocardiogram information on the basis of a first electrocardiogram record; training an artificial intelligence segmentation model on the basis of the first electrocardiogram record and the first electrocardiogram information; segmenting a second electrocardiogram record into second electrocardiogram information by using the second electrocardiogram record as an input of the trained artificial intelligence segmentation model; and converting the segmented second electrocardiogram information into a digital electrocardiogram signal.

3 GUIDE INSTRUMENTS BASED ON 3-DIMENSIONAL PRINTING FOR OSTEOTOMY AND BON FIXATION AND METHOD OF FABRICATING THE SAME

Nº publicación: KR20260123841A 14/08/2026

Solicitante:

재단법인아산사회복지재단울산대학교산학협력단