Absstract of: WO2026217664A1
Provided is a method including obtaining a first volumetric image dataset of an anatomical region of a patient, obtaining a planned resection model associated with the first volumetric image dataset, the planned resection model indicating a surgeon-planned resection region within the anatomical region, receiving optical image data of the anatomical region captured during a surgical procedure, receiving a signal indicating that a resection progress measurement is to be initiated, constructing a three-dimensional mesh reconstruction of tissue visible in the anatomical region during the surgical procedure, determining an updated anatomical model using the first volumetric image dataset, the three-dimensional mesh reconstruction, and a model configured to update the first volumetric image dataset to account for intraoperative tissue displacement in the anatomical region, comparing the updated anatomical model with the planned resection model to determine a resection progress indication relative to the surgeon-planned resection region, and presenting an output indicating resection progress.
Absstract of: US20260315778A1
Methods and apparatus of detecting an obstruction event associated with operation of a heart pump are provided. The method includes receiving a motor current signal associated with a motor of the heart pump, receiving a pump speed signal associated with the heart pump, detecting, using a computer processor, an obstruction event, and displaying, when an obstruction event is detected, an indication of the obstruction event on a user interface associated with the heart pump. Detecting the obstruction event is based, at least in part on a first value of the motor current signal being above a first threshold value at a first time, and a second value associated with the pump speed signal being less than a second threshold value at a second time, wherein the first time and the second time are within a time window having a length of 120 ms or less.
Absstract of: US20260315177A1
0000 Adjusting illumination sources based on stages of ophthalmic surgery is described. An ophthalmic surgical system may include a first illumination source configured to produce a first light beam for illuminating a surgical region of an eye, upon which an ophthalmic surgical procedure is being performed, from a first direction, and a second illumination source configured to produce a second light beam for illuminating the surgical region of the eye from a second direction. The ophthalmic surgical system may further include a surgical stage-based illumination module implemented in a non-transitory computer-readable storage medium and configured to determine, in real-time, a stage of the ophthalmic surgical procedure based on a detected trigger event. The surgical stage-based illumination module may be further configured to output, in real-time, instructions to adjust at least one of the first illumination source or the second illumination source based on the stage of the ophthalmic surgical procedure.
Absstract of: AU2025245072A1
Orthodontic treatment planning involves determining the desired treatment positions for a patient's teeth. The desired treatment positions may include both aesthetic and clinical considerations that describe the spatial relationship of teeth relative to each other. The inventors have recognized and appreciated that existing techniques, for orthodontic treatment planning, struggle to provide suitable orthodontic treatment plans without substantial involvement from orthodontic clinicians.
Absstract of: US20260315020A1
0000 Systems and methods of deep-learning diagnosis of plaque erosion using coronary computed tomography angiography (CTA). One system may include one or more electronic processors configured to receive a plurality of CTA images for a patient having acute coronary syndromes (ACS) and apply a machine learning model to the plurality of CTA images to determine a plaque erosion prediction.
Absstract of: US20260321368A1
An information processing assessment booth may be provided with a base panel, having a trapezoidal surface defined in a first plane with a front edge parallel to a back edge, and first and second side edges disposed at a first angle between the front edge and the back edge; a first side panel attached to the first side edge of the base panel, extending perpendicularly to the first plane; a second side panel attached to the second side edge of the base panel, extending perpendicularly to the first plane; a roof panel, connected between the first side panel and the second side panel in a second plane that intersects the first plane; and a divider, connected between the first side panel, the second side panel, the roof panel, and the base panel, extending perpendicularly from the base panel and including a video display device and a video recording device.
Absstract of: US20260317704A1
A vascular plant based cellulose scaffold for in-vitro production or growth of neural stem cells is provided. The scaffold may be obtained by decellularizing a vascular plant or a part thereof and is capable of supporting the growth of neural stem cells. The scaffold may be coated with any traditional coating known in the art such as a biomolecule, a synthetic biomolecule (Poly-L-Ornithine), a ligand, a protein, an amino acid, an antibody, an extracellular matrix, fibrin, laminin, collagen, fibronectin, poly-l-lysine, a small molecule, a hydrogel, or a matrigel. An in-vitro method of growing or producing neural stem cells is also provided.
Absstract of: US20260321422A1
0000 A system and method for analyzing a sputum sample from a subject suspected of having lung cancer comprising obtaining a plurality of cells from the sputum sample from the subject, marking the plurality of cells with i) a plurality of cell lineage specific marker compositions, ii) a cell viability composition and iii) a tetra (4-carboxyphenyl) porphyrin (TCPP) composition; analyzing with the flow cytometer the plurality of cells marked with i-iii to obtain a subpopulation selected for cell size from the plurality of cells based upon an automatically selected bead size exclusion gate; from the cell size selected subpopulation, selecting a viable singlet population of cells using an automated non-debris gate and an automated singlets gate; from the viable singlet population of cells, obtaining flow cytometer values based upon the plurality of cell lineage specific marker compositions, the viability marker and the TCPP marker; applying a trained classifier to meta data from the subject and the flow cytometric values obtained; and generating, based upon the application of the trained classifier, a classification for the sputum sample wherein the classification is selected from a plurality of classification options comprising cancer and non-cancer.
Absstract of: WO2023096914A1
Approaches for generating a set of biomarkers and generating a summary and one or more recommendations based, at least in part, upon the biomarkers are provided. Sensor data associated with a user may be received. The sensor data may be analyzed to generate a set of biomarkers. One or more biomarkers of the set may be combined to generate one or more additional biomarkers. A summary and one or more recommendations may be generated based, at least in part, upon the generated set of biomarkers and the additional biomarkers. The generated summary and the one or more recommendations may be provided for display on a client device.
Absstract of: US20260315011A1
0000 A method for generating a diagnosis via a digital health application includes receiving, by a digital health application, a request for a diagnosis. A digital health application selects a plurality of questions based on the initial complaint, an order of presenting each of the plurality of questions, the order associated with the plurality of questions. The digital health application displays, to a user of the digital health application, in the associated order, each of the plurality of questions. The digital health application receives user input responsive to the questions. The digital health application determines a diagnosis and modifies a user interface to display an identification of the determined diagnosis. The digital health application requests an indication of whether the user of the digital health application accepts the diagnosis. The digital health application requests an indication of whether to establish a consultation with a medical professional to discuss the diagnosis.
Absstract of: AU2025229905A1
The present invention provides an improved breath analyzer and breath test method to determine the presence of disease in humans, including but not limited to, H. pylori infection, Celiac Disease, Metabolic dysfunction-associated steatohepatitis (MAHD), Inflammatory Bowel Disease (JBD). 'm a subject's digestive tract. In certain embodiments, the present invention provides a universal breath testing platform and methods of testing for diseases of the gastrointestinal tract, the liver, the kidneys, and the lungs, along with testing for cancer, infections, and metabolic diseases.
Absstract of: US20260315188A1
The method for designing a transparent orthodontic appliance and attachment for tooth alignment according to the present invention has been devised to solve the above technical problems. It is a method for designing an orthodontic appliance using a computer, comprising: a step (S01) of designing the shape of an attachment to be affixed to the surface of a tooth model; a step (S02) of designing the inner surface shape of the transparent orthodontic appliance corresponding to the attachment designed in step S01; and a step (S03) of outputting the transparent orthodontic appliance by means of a 3D printer. The attachment comprises: two pressure surfaces (101) formed to face each other; two inclined surfaces (201) formed to be inclined toward each other while contacting the two pressure surfaces (101); a top surface (301) contacting the edges of the two pressure surfaces (101) and the two inclined surfaces (201); and an attachment surface (401) affixed to the surface of a tooth. This configuration serves as the technical means for solving the problem.
Absstract of: US20260315872A1
0000 A method for optimizing at least one exercise for a first user. The method includes receiving first user data including attribute data associated with the first user and outcome data associated with the exercise. The method includes generating, based on the first user data, initial target data. The initial target data is associated with at least one of the first user, the exercise apparatus, and the exercise. The method includes receiving measurement data associated with at least one of the first user, the exercise apparatus, and the exercise. The measurement data is associated with one or more sensors. The method includes determining differential data based on one or more differences between the initial target data and the measurement data. The method includes generating, via an artificial intelligence engine and based on the differential data, a machine learning model trained to generate optimized target data.
Absstract of: US20260318919A1
In a general aspect, methods and devices are provided for using mass spectrometry to identify endometriosis. In some aspects, a fixed or discrete volume of a solvent is applied to a tissue site including possible endometriosis tissue. The applied solvent is collected to obtain a liquid sample. The liquid sample is subjected to mass spectrometry analysis. The liquid sample is collected from a tissue site in vivo during a medical procedure. The mass spectrometry data are analyzed to identify whether the tissue site comprises endometriosis.
Absstract of: AU2026238015A1
Abstract Biomimetic scaffolds for neural tissue growth are disclosed herein which have a plurality of microchannels disposed within a sheath. Each microchannel comprises a porous wall that is formed from a biocompatible and biodegradable material. The biocompatible and biodegradable material may be polyethylene glycol) diacrylate, methacrylated gelatin, methacrylated collagen, or polycaprolactone, and combinations thereof. The biomimetic scaffolds have high open volume % enabling superior (linear and high fidelity) neural tissue growth, while minimizing inflammation near the site of implantation in vivo. Abstract
Absstract of: US20260315692A1
0000 An infusion device control system intercepts a first command provided to a first infusion pump by a closed-loop control algorithm, the first command configured to adjust delivery of a first fluid by the first infusion pump according to sensor measurements provided to the closed-loop control algorithm. The control system receives a therapy target control parameter for modifying the delivery of the first fluid based on a real time parameter for delivering a second fluid by a second infusion pump, receives real time operating parameters and infusion status information associated with the first and second infusion pumps, and modifies the intercepted first command based on the real time operating parameters and infusion status information and the therapy target control parameter to control an effect of the deliveries of the first and second fluids, without providing input for modifying the intercepted first command to the closed-loop control algorithm.
Absstract of: US20260318304A1
A catheter blood pump includes a cannula with an expandable central portion having a proximal end, a distal end and a blood flow conduit therebetween. A flexible inlet portion at the distal end is provided with a plurality of spaced apart inlet struts configured to prevent an obstruction from entering, and a flexible outlet portion is provided with a plurality of spaced apart outlet struts operative to reduce a swirl velocity of blood, wherein the plurality of spaced apart inlet struts and the plurality of spaced apart outlet struts are fabricated from a collapsible shape memory material.
Absstract of: US20260320778A1
In order to address the problem that specifying information and giving advice on a kinesiological state of the body of a user require specialized knowledge and experience and the effort and cost required are relatively high, an information processing apparatus 100 includes: a sole information acquiring unit 141 that acquires sole information on a sole of a user; a determination information acquiring unit 149 that acquires determination information on a kinesiological state of the body of the user, using the sole information and learning information that is prepared in advance; an output information acquiring unit 151 that acquires output information based on the determination information; and an output unit 161 that outputs the output information. Accordingly, it is possible to easily specify information on a kinesiological state of the body of a user.
Absstract of: US20260314958A1
0000 The present invention proposes a method of measuring the real-time level and degree of management of blood sugar based on an electrocardiogram. The method includes: obtaining an electrocardiogram signal measured for a user; estimating the user's blood sugar level by analyzing the electrocardiogram signal using a pre-trained first artificial intelligence, and determining whether the user has hyperglycemia or hypoglycemia by analyzing the electrocardiogram signal using an artificial intelligence; and determining whether the user needs guidance on blood sugar or diabetes based on the estimated blood sugar level and the result of the determination of whether the user has hyperglycemia or hypoglycemia. Through this, a user may check the user's immediate blood sugar level and how well the blood sugar is managed simply by measuring the electrocardiogram 10, and as a result, hyperglycemia and diabetes may be detected early or a complication attributable to hyperglycemia or diabetes may be prevented.
Absstract of: US20260315190A1
0000 The present invention patent relates to an orthodontic envelope multiple alignment device, pertaining to the technical field of accessories for orthodontic treatment, and more particularly to a multiple alignment device made up of a dental arch (A) that forms a single body (1), having two or three layers (11, 12 and 13) containing between them various accessories (AC) such as: an archwire or archwires and/or brackets and/or buccal tubes and/or other accessories. The layer (11) is formed by individual crowns WO (111) for receiving the accessories (AC), and each of the layers (12 and 13) is formed as a single piece. The layers are formed by a sheet (F) that receives, positions, fits, protects and envelops the dental arch (A) and the accessories (AC), the sheets (plates) being produced from transparent materials such as PET, PET-G, polyurethane, acetate or equivalent materials, wherein each of the sheets (plates) is produced individually using a vacuum forming and/or thermoforming manufacturing process and/or using direct 3D printing manufacturing process, or as a coating applied by spraying or with a brush, or any other available process. Optionally, the layers (11, 12 and 13) can be produced using a liquid material (ML) or a paste. Also, optionally, the layer (11) is provided with a crown (111) for receiving the accessories (AC), wherein the crown is transparent or opaque.
Absstract of: US20260321408A1
An apparatus comprises at least one processing device implementing a fleet management device for a fleet of one or more monitoring devices associated with one or more users. The at least one processing device is configured to obtain, from the one or more monitoring devices, monitoring data comprising at least one of physiologic and localization data for the one or more users. The at least one processing device is also configured to detect, based at least in part on the obtained monitoring data, one or more designated conditions associated with at least one of the one or more users, and to control, based at least in part on the detected one or more designated conditions associated with said at least one of the one or more users, one or more operating parameters for at least one of the one or more monitoring devices.
Absstract of: US20260315197A1
Systems and techniques for training one or more machine learning models to generate digital representations of dental restoration tooth geometry are disclosed including generating one or more digital representations that define a restored state for a first digital representation, determining one or more differences between the one or more predicted representations for the restored state and the one or more reference representations of the restored state, and modifying the machine learning model based on the determined differences.
Absstract of: AU2026238109A1
A method for surgical planning includes obtaining, by a computing system, a first point cloud representing a first portion of a bone or a first cloud representing at least a portion of a bone, applying, by the computing system, a point cloud neural network to generate a second point cloud based on the first point cloud, the second point cloud comprising at least one of points representing at least a second portion of the bone or points representing an axis along the bone, and generating, by the computing system, surgical planning information based on the second point cloud. ep e p
Absstract of: US20260315133A1
0000 Disclosed in the present invention are an automatic determination method and system for ultrasound ablation balloon apposition. The method comprises the following steps: setting related working parameters; after a balloon moves to a target ablation area, injecting normal saline; measuring a pressure in the balloon and an impedance outside the balloon, and feeding back same to a control system; and determining whether the balloon fits with the wall of a blood vessel well. According to the technical solution of the present invention, a pressure in a balloon and an impedance outside the balloon are measured at the same time and compared with set values and set change ranges, such that accurate and automatic determination of an ultrasound ablation balloon fitting with the wall of a blood vessel is achieved, and it is ensured that ablation operation is started after the ultrasound ablation balloon fits with the wall well, thereby greatly improving the ultrasonic transmission efficiency and the ablation operation effect.
Nº publicación: US20260315189A1 15/10/2026
Applicant:
ALIGN TECH INC [US]
Align Technology, Inc.
Absstract of: US20260315189A1
0000 Disclosed herein are methods for manufacturing medical devices, such as implants, joint replacements, graft materials, augmentation materials, prosthetic materials, etc., from solid material reinforced curable resins. Methods of repositioning a patient's teeth using such medical devices are also provided.