Absstract of: US20260315054A1
0000 A closure device for closing a hole or duct in a heart or a tissue continuous to the heart, comprises a connection part detachably connected to a delivery cable; a first plate including a base layer containing a resin having elastic restorability; a first center part, and a first extension part extending around the first center part; and a first waist part connected to the first center part, wherein the closure device is configured to be delivered to the hole or duct through the catheter in conjunction with the delivery cable, with the ability to rotate in conjunction with the rotation of the delivery cable, and the first plate is shaped to match a shape of the hole or duct of a patient, and includes a marker enabling confirmation of a rotational angle of the closure device via an examination apparatus including ultrasound.
Absstract of: US20260316399A1
0000 The invention provides a solid-dosage-form printing apparatus comprising: i) a 3D printer suitable for printing solid-dosage-forms, said 3D printer comprising an interchangeable print head selected from the group consisting of: a fused deposition modelling print head, a semi-solid extrusion print head and a direct powder extrusion print head; ii) a build platform; iii) a balance for measuring the mass of the printed solid-dosage-forms, said balance being integrated into said build platform; and optionally iv) means for performing in-line near-infra-red and/or raman spectroscopy on the solid-dosage-form product; wherein said solid-dosage-form comprises at least one active-ingredient and at least one excipient. Further provided are methods of producing solid-dosage-forms using the apparatus, including computer-implemented methods.
Absstract of: US20260317554A1
A curable composition has a polymerizable monomer and a hard solid component having a volume average particle diameter of 10 nm or greater and 1,000 nm or less. The content of the hard solid component is 3% by volume or greater and 40% by volume or less. The difference (n1−n2) between the refractive index (n1) of a cured product of any other component than the hard solid component and the refractive index (n2) of the hard solid component is 0.04 or greater.
Absstract of: US20260315329A1
Introduced here are containers designed to promote compliance with regimens for administering the medications stored therein. These containers can facilitate the conveyance of information related to a regimen through the use of a non-written medium. A container may include one or more display elements configured to emit/reflect light to indicate when medication stored in the container should be administered. An example of a display element is a light-emitting diode (LED). Emittance/reflectance of the light by the display element(s) may be governed by a different clock signal than the clock signal used to determine whether doses of medication are due to be administered.
Absstract of: US20260321407A1
0000 A cleaning apparatus management unit manages the utilization status of a first cleaning apparatus that can clean an endoscope that has been manually cleaned in a procedure in which one or more steps are skipped and the utilization status of a second cleaning apparatus that can clean an endoscope that has been manually cleaned by performing all the steps. A reception unit receives step information indicating a completed step during the manual cleaning of the endoscope. When the received step information indicates a predetermined step that comes before a final step, an assignment processing unit determines a cleaning apparatus to be assigned to the endoscope based on the relationship between scheduled completion time of the manual cleaning when the implementation of the one or more steps that come after the predetermined step is skipped and the utilization status of a plurality of cleaning apparatuses managed by the cleaning apparatus management unit.
Absstract of: AU2025257325A1
The present invention relates to a computer-implemented method for clustering defects of defective bones and manufacturing a patient-specific orthopaedic implant, including at least the following steps: - acquiring computed tomography CT images of a defective or damaged bone and feeding a database; - given a set of defective bones retrieved from said defective or damaged bone database, reconstructing a synthetic shape of the original shape of the defective bone; - computing a bone erosion depth map of said synthetic shape of the original shape of the defective bone, where said bone erosion depth map, for a given defective bone, comprises a set of erosion values over the region of interest of the reconstructed bone, defining an erosion vector; - transforming said erosion depth map into an erosion matrix which comprises the erosion vectors of the defective bones and the vertices over the surface of the region of interest of said synthetic shape of the original shape of the defective bone; - feeding said erosion matrix to an unsupervised machine learning algorithm that groups data into a tree of nested clusters, to identify clusters of relevant bone defects and to generate synthetic three-dimensional bone models representative of each defect cluster; - associating a defect label to each cluster; - training a defect classifier using said erosion matrix and said defect label to classify clusters of defects of the bones; - feeding a CAD environment with the outputs of said defect c
Absstract of: US20260320367A1
Systems and methods are disclosed for modulating neural pathways to improve functional ability in a subject. The systems and methods may contain steps, including: receiving a first dataset associated with activity of one or more neural pathways of the subject; receiving a second dataset comprising at least one of at least one task performed by the subject, at least one symptom, and at least one medical condition of the subject; determining one or more abnormal neural pathways based on the first dataset and the second dataset; determining from the second dataset, one or more healthy neural pathways associated with the one or more abnormal neural pathways based on one or more criteria; and determining, based on the healthy neural pathways and abnormal neural pathways, and using a non-invasive stimulatory device, a stimulus input focused or differentiated to the healthy neural pathways.
Absstract of: US20260321158A1
0000 The object of the present invention is a surgical simulator (1) for training and preoperative planning of a surgical operation, such as aneurysm clipping and/or endovascular treatment, comprising: —a support (4) comprising a support body (5) externally delimited by a support external surface (6) having a paradigmatic shape of a body portion of a patient, such as a paradigmatic shape of a skull, so that the support (4) is clampable on the support external surface (6) to simulate a positioning phase of preoperative planning, wherein the support (4) delimits at least a cavity (7, 9) in the support body (6) and a respective cavity aperture (8, 10) on the support external surface (6) for accessing to the respective cavity (7, 9); —at least an anatomical simulator (2, 2′, 3, 3′) that is supported by the support (4), wherein a first anatomical simulator (2, 2′,) of the at least an anatomical simulator (2, 2′, 3, 3′) is removably housed into a first cavity (7) of the at least a cavity (7,9), wherein each anatomical simulator (2, 2′, 3, 3′) comprises at least a respective vascular phantom (11) and a respective container (12) configured to support the vascular phantom (11) , wherein the vascular phantom (11) of each anatomical simulator (2, 2′, 3, 3′) comprises a vascular wall (13) delimiting an hollow structure, the vascular wall (13) being 3D printed in order to replicate a patient-specific vascular structure or a modelled vascular structure.
Absstract of: US20260315157A1
0000 A surgical 3D marker element has a surface, on or in which a two-dimensional optical pattern is permanently incorporated or applied, for spatial position detection of a medical product. The optical pattern is in the form of a matrix with M rows and N columns with corresponding pattern elements as pattern fields. The optical pattern has at least four pattern elements, of which at least two pattern elements are designed differently to provide an optical reference for position detection of the 3D marker element via an optical tracking system. The 3D marker element can be part of or used with a medical product, a tracking system, a position detection method, a computer-readable storage medium and a computer program.
Absstract of: WO2023133124A2
Acellular substrates that provide continuous 3D growth of a variety of cells and/or tissues and methods of making the same are provided. The acellular substrates have a three- dimensional (3D) macrostructure defined by a continuous matrix of extracellular matrix (ECM) material associated with a first cell type of interest and a network of microporous channels and/or chambers extending throughout the continuous matrix of ECM material associated with the first cell type of interest. Methods of forming a personalized graft using a patient's own cells is also provided.
Absstract of: AU2026238022A1
Abstract Disclosed is respiratory assistance apparatus comprising a flow generator configured to provide breathing gases to a patient, the breathing gases comprising supplemental oxygen provided from an oxygen source. The respiratory assistance apparatus controller is configured determine a target oxygen concentration of the breathing gases and calculate an estimated future value of the patient’s blood oxygen concentration based on a difference between an initial oxygen concentration of the breathing gases and the target oxygen concentration of the breathing gases, and the patient’s blood oxygen concentration. Abstract ep b s t r a c t e p
Absstract of: US20260321439A1
0000 The presently disclosed subject matter aims to a system and method for evaluating the level of harassment of flying insects on a plurality of animals located at a given area, the system comprising a processing circuitry configured to: obtain one or more ear movement patterns associated with at least one ear of at least one animal of the plurality of animals, each ear movement pattern is associated with respective ear movement characteristics; for at least part of the one or more ear movement patterns, determine whether their respective ear movement characteristics meet a predefined rule; and, determine whether a number of ear movement patterns whose ear movement characteristics met the predefined rule meets an action requirement rule.
Absstract of: US20260321378A1
0000 Provided are systems and methods using which users may learn and become familiar with the effects of various aspects of their lifestyle on their health, e.g., users may learn about how food and/or exercise affects their glucose level and other physiological parameters, as well as overall health. In some cases the user selects a program to try; in other cases, a computing environment embodying the system suggests programs to try, including on the basis of pattern recognition, i.e., by the computing environment determining how a user could improve a detected pattern in some way. In this way, users such as type II diabetics or even users who are only prediabetic or non-diabetic may learn healthy habits to benefit their health.
Absstract of: WO2022150486A1
An animal data compliance system includes one or more sources of animal data from one or more targeted individuals wherein the animal data is transmitted electronically. A collecting computing device gathers the animal data. One or more rules related to at least a portion of the animal data are created or modified based upon one or more terms. The one or more rules are associated with at least a portion of the animal data. At least a portion of animal data and the one or more rules are provided to one or more receiving computing devices. The one or more rules informs the one or more receiving computing devices of one or more permissions or restrictions related to the animal data. The one or more receiving computing devices take at least one action based upon the one or more rules.
Absstract of: WO2022124190A1
Problem Finding objective information about the condition of intestines was difficult with conventional information processing devices. Solution An information processing device 100 capable of obtaining objective information about the condition of intestines, comprising: a sound information acquisition unit 141 that acquires sound information pertaining to abdominal sounds that are emitted from the abdomen of a user; an intestinal score acquisition unit 149 that acquires an intestinal score pertaining to the state of the intestines of the user, by using input information including sound information acquired by the sound information acquisition unit 141 and prepared training information; and an intestinal score output unit 161 that outputs the intestinal score acquired by the intestinal score acquisition unit 149.
Absstract of: US20260315202A1
An electronic device includes a wireless communication circuit, a display, a processor, and a memory for storing instructions. The instructions may be executed by the processor to cause the electronic device to: identify first data related to an electronic medical record of a user based on detection of a first external electronic device and a first object related to a tooth brushing activity; determine, based on the first data, a first tooth brushing pattern related to the tooth brushing activity; receive second data related to the tooth brushing activity from the first external electronic device; identify, based on the second data, a second tooth brushing pattern indicated by the tooth brushing activity; determine the similarity between the first tooth brushing pattern and the second tooth brushing pattern; and display guide information based on the first tooth brushing pattern based on determining that the similarity is less than a threshold level.
Absstract of: US20260314959A1
0000 A medical system comprising: an analyte sensor for receiving an analyte signal corresponding to an analyte concentration of a user; a health monitor device comprising a display unit and in communication with the analyte sensor, the health monitor device comprising a processor and memory communicably coupled to the processor, the memory including instructions stored therein that, when executed by the processor, cause the processor to: receive the analyte signal from the analyte sensor; determine the analyte concentration based on the analyte signal; calculate a recommended medication dosage based on the analyte concentration; associate a current parameter type with the recommended medication dosage; associate the current parameter type to at least one corresponding stored historical parameter type associated with a historical medication dosage; and display, on the display unit, the recommended medication dosage and the historical medication dosage.
Absstract of: US20260315010A1
A system for patient body imaging with live feed medical video consultation. The system includes an imaging booth with a plurality of cameras for capturing body images of a patient, a server for storing and transmitting patient images and patient information, a computer and/or mobile computing device in communication with the server, and a computer processing unit in communication with a program application that includes the ability to conduct or schedule a live feed video consultation between the patient and a medical provider where the live feed video consultation enables both the patient and the medical provider to view the patient’s body images. The imaging booth may be a foldable total body imaging apparatus that includes a foldable floor to produce a compact folded apparatus having a small footprint when not in use.
Absstract of: US2020268991A1
0001 A system and method is disclosed for performing diagnostics on patient devices. The patient devices may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server may maintain a database of diagnostic data indicating faults in one or more of a plurality of patient devices. The server may transmit this diagnostic data to one or more computing devices, including identification of faults that have occurred. The server may also transmit service data to the plurality of patient devices in order to address the identified faults.
Absstract of: WO2025079951A1
The present invention relates to a method for designing, using a computer, an orthodontic device on the basis of partial designation of teeth, the method being characterized by comprising the steps of: displaying the arrangement of teeth of a patient (S01); setting up and displaying all the teeth in the arrangement of teeth in the state after orthodontics (S02); designating teeth in the teeth arrangement (S03); designating specific portions in the designated teeth (S04); and inputting the thickness of the orthodontic device in contact with the specific designated portions in the designated teeth (S05).
Absstract of: US20260315658A1
The present disclosure provides devices comprising a therapeutic agent bound to a printed three-dimensional structure. Ink formulations for three-dimensional printing are also disclosed. Additionally, provided herein are methods for manufacturing devices and uses thereof, e.g., in treating a condition in a subject in need thereof.
Absstract of: US20260316400A1
Provided are a method for producing a three-dimensional object and an ink set for producing a three-dimensional object, which can produce even, for example, a complex-shaped three-dimensional object made of a soft material with good fabrication accuracy. The present invention relates to a method for producing a three-dimensional object, including individually discharging (a) a model material ink containing a photocrosslinkable polymer and (b) a support material ink containing a support material and a first crosslinking factor, photocuring the discharged photocrosslinkable polymer, and removing an object of the support material ink.
Absstract of: US20260323172A1
0000 A 3D scanner includes one or more projectors configured to emit a projector image including either lines or stripes on to a mirror that reflects the projector image onto an object, an optical lens configured to shorten a focal length emitted from the projector and defocus the projector image in at least one dimension, wherein the defocusing is in a direction substantially parallel to the lines or stripers, a first camera and second camera configured to capture one or more images from the object resting and the projector image is on the object, and a processor programmed to receive, from the first camera and the second camera, the one or more images from the object, and in response to removing noise from the one or more images, output a 3D scan of the object.
Absstract of: WO2026217551A1
A prosthetic eye or aesthetic contact lens and methods of manufacture of the same using additive manufacturing. Methods may include scanning a functional eye of a user to generate a prosthetic eye model matching the coloring and sizing features of the scanned eye. A substrate is positioned relative to one or more print heads, which deposit polymerizable mixtures as deposited droplets to form the sclera portion, vein pattern, and iris structure. A first polymerizable mixture may replicate a natural sclera, a second polymerizable mixture may form natural features, such as vein patterns, and a third polymerizable mixture may create an iris with a pupil region. Tire prosthetic eye may include an internal cavity filled with a liquid solution to allow iris movement, liquid pouches for hydration or medication, and integrated electronic components such as cameras, sensors, and wireless communication modules.
Nº publicación: WO2026217648A1 15/10/2026
Applicant:
AUXILIUM BIOTECHNOLOGIES INC [US]
AUXILIUM BIOTECHNOLOGIES INC.
Absstract of: WO2026217648A1
The system, methods, and uses of three-dimensional micromanufacturing materials, scaffolds, and living tissues in microgravity environment that is found in space such as Low-Earth-Orbit, on a spacecraft in-transit between celestial bodies, or on other celestial bodies such as the Moon or Mars.