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166
results.
Updated on
21/02/2026 [07:21:00]
Results 75 to 100 of 166
Absstract of: CN121466360A
本发明公开一种适用于增材制造的骨骼材料及其制备方法，方法包括以下步骤：S1、将CNTs加入乙醇中，搅拌，超声分散，获得CNTs乙醇分散液；S2、将PEEK粉体加入CNTs乙醇分散液中，搅拌，超声分散，获得CNTs‑PEEK‑乙醇共混液；S3、将CNTs‑PEEK‑乙醇共混液搅拌直至重量不再减少，获得CNTs‑PEEK粉体；S4、将CNTs‑PEEK粉体烘干后，挤出，获得CNTs‑PEEK线材；S5、将CNTs‑PEEK线材再次烘干后，利用高温融熔挤出打印，获得个性化骨骼支架；本发明提供了一种适用于增材制造的、力学性能好且不容易脆性断裂的骨骼材料及其制备方法。
Absstract of: CN121466382A
本发明一种集成剪切激活微胶囊的自固化角蛋白3D打印墨水及其制备方法，属于生物3D打印和智能材料技术领域，将高分子量可溶性角蛋白粉末溶解于pH为6.5‑8.5的生物相容性水性介质中，混合均匀，脱泡后得到角蛋白基液；将芯材包裹于相应的外壳内，得到成平均粒径为1‑10 μm的微胶囊；在搅拌条件下，将所述微胶囊均匀地分散到0~8°C的角蛋白基液中，直至形成均一的悬浮体系，得到集成剪切激活微胶囊的自固化角蛋白3D打印墨水。墨水的固化过程内化于打印行为本身，简化了打印流程，降低了设备成本和操作难度。由于交联剂被有效隔离，墨水在打印前可稳定储存数周而不会发生凝胶，解决了双组分墨水混合后必须立即使用的难题。
Absstract of: CN121465752A
本发明公开了一种用于口颌面畸形的矫正修复器及其制作方法，属于口腔医学修复与矫正技术领域，其修复器包括上颌组件和下颌板，上颌组件下端连上支撑组件，下颌板上端两侧连下支撑杆；上支撑组件和下支撑杆远离颌部一侧连用于套设牙齿的上、下套托，上套托和下支撑杆另一侧连多个托槽组件；托槽组件含单晶氧化铝陶瓷托箱、医用不锈钢封闭板及伸缩连杆；上支撑组件的上支撑杆与下支撑杆端部分别设氧化锆陶瓷上、下咬合块；制作时，通过口内扫描、影像确定参数，CAD设计部件，采用激光烧结和3D打印模型，装配各部件后佩戴。
Absstract of: CN121466359A
本发明属于材料制备技术领域，具体涉及一种超结构玻璃碳在促骨修复中的应用及骨修复材料的制备方法。本发明首先提供了一种骨修复材料，所述骨修复材料由一种经过表面改性的玻璃碳材料制备得到；所述玻璃碳材料具有各向应力均匀分布的稳定结构；所述超结构玻璃碳以三周期极小曲面的晶胞作为最小重复单元；经过表面改性后的玻璃碳材料具有珊瑚样或类珊瑚样形貌。本发明的骨修复材料可以实现诱导骨组织加速修复和再生，此外这种骨修复材料还兼顾了很好的力学性能。
Absstract of: AU2025205647A1
An implant having two adjacent solid parts, a third solid part disposed between the two solid parts, and a porous part extending from the solid parts. The implant is fabricated by a process that includes first assembling the solid parts before additively manufacturing the porous part on surfaces defined by the solid parts. This process may include positioning a first fabricated component adjacent to a second fabricated component such that a side surface of the first fabricated component and a side surface of the second fabricated component form a build surface. Then additively manufacturing a structure on the build surface such that the structure extends across and is permanently fixed to both of the side surfaces of the first and the second fabricated components such that the first and the second fabricated components form part of the implant. An implant having two adjacent solid parts, a third solid part disposed between the two solid parts, and a porous part extending from the solid parts. The implant is fabricated by a process that includes first assembling the solid parts before additively manufacturing the porous part on surfaces defined by the solid parts. This process may include positioning a first fabricated component adjacent to a second fabricated component such that a side surface of the first fabricated component and a side surface of the second fabricated component form a build surface. Then additively manufacturing a structure on the build surface such that th
Absstract of: WO2026030357A1
Disclosed herein is a microfluidic device for priming, collection and recovery of immune cells comprising: a) two separate fluidic channels: i) a first channel, wherein the first channel is infused with immune cells, and ii) a second channel, wherein the second channel acts as a collection reservoir for transmigrated cells, and; b) a microporous membrane interface, present between the first channel and the second channel, wherein the microporous membrane is functionalized on the first channel surface with adhesion molecules. Also disclosed are methods of creating enhanced cells, and using them in treatment of individuals in need thereof.
Absstract of: US20260034341A1
Pliers for engaging an aseptic connection assembly is disclosed. The pliers has two arms. Each arm includes a hinge portion, a handle portion, and a pair of phalanges. The hinge portion has a hole for forming a hinge. The handle portion couples to the hinge portion. The pair of phalanges is on a plane perpendicular to the plane of rotation of the two arms and is coupled to the hinge portion. The phalanges couple to sides of outer surfaces of a pair of connector bodies. The hinge is formed by a rod inserted through the holes of the hinge portions of the two arms. An actuation force applied to the handle portions causes the two arms to rotate about the hinge, causing the pair of phalanges to move together to snap together the pair of connector bodies, thereby engaging the aseptic connection assembly.
Absstract of: US20260033957A1
In one embodiment, an intervertebral implant includes a body and a locking element. The body includes a leading surface and a trailing surface opposite the leading surface. The body also includes first and second bone fastener passageways through the implant body and a cavity in between the first and second passageways. The cavity includes a trailing wall that separates the cavity from the trailing surface. The locking element is disposed in the cavity such that part of the locking element is visible through an access opening in the trailing wall so that the locking element may be rotated from outside of the implant. In a first rotational position, a first part of the locking element is located within one of the first and second passageways and in a second rotational position, the first part of the locking element is inside the body covered by the trailing wall.
Absstract of: US20260033918A1
The present disclosure provides a support of a 3D printed orthodontic dental appliance is provided. The orthodontic dental appliance includes a shell structure defined by an inner contour surface and an outer contour surface. The support comprises: a middle support including a middle support base mesh and a plurality of middle support struts and a main support configured to connect the middle support to a build platform of a 3D printing device used to print the orthodontic dental appliance. One end of each middle support strut of the plurality of middle support struts is connected to the orthodontic dental appliance at a junction of the inner contour surface and the outer contour surface, and the other end of the middle support strut is connected to a rim of the middle support base mesh.
Absstract of: US20260033920A1
Wire attachment dental appliances. A shell may be shaped to receive teeth of a dentition. The shell may include an attachment material reservoir that is configured to accept an attachment material therein. A wire attachment member may be configured to be secured to the shell. The attachment material reservoir and the wire attachment member may be aligned along an arch line of the shell in a manner that allows a wire to simultaneously pass through the attachment material reservoir and engage with the wire attachment member.
Absstract of: US20260033923A1
A system and method for generating a 3D-printed medical appliance treatment plan and providing a set of 3D-printed medical appliances in accordance therewith, the method comprising: generating a dynamic 3D-printed medical appliance treatment plan generation model; obtaining a patient record; receiving 3D scanning data of the patient; generating a 3D-printed medical appliance treatment plan by applying the patient record and the 3D scanning data to the dynamic 3D-printed medical appliance treatment plan generation model; providing the 3D-printed medical appliance treatment plan to a medical practitioner; providing a manufacturing request to a manufacturer system for manufacturing a set of 3D-printed medical appliances; providing the set of 3D-printed medical appliances to the patient; receiving feedback from the medical practitioner regarding the 3D-printed medical appliance treatment plan; modifying the dynamic 3D-printed medical appliance treatment plan generation model based on the feedback.
Absstract of: US20260035592A1
Provided is a cationically polymerizable resin composition for three-dimensional photofabrication that contains a cationically polymerizable monomer (A), a photocationic polymerization initiator (B) containing a photoacid generator (b1), a photosensitizer (b2), and an electron-donating compound (b3) that is at least one type of thiophene compound selected from the group consisting of monothiophene compounds having a π-conjugated substituent as a substituent, dithiophene compounds, and trithiophene compounds, and a basic compound (C). The content of the electron-donating compound (b3) is 0.001-10 parts by mass and the content of the basic compound (C) is 0.0001-5.0 parts by mass per 100 parts by mass of the cationically polymerizable monomer (A). Also provided is a method for producing a three-dimensional photofabricated product using this cationically polymerizable resin composition for three-dimensional photofabrication.
Absstract of: CN120603620A
A drug delivery device comprises at least one tissue penetrating member configured to be embedded in tissue, the at least one tissue penetrating member comprising: at least one lumen formed below an outer surface of the at least one tissue penetrating member, the at least one cavity has a depth from the outer surface and a width in a direction orthogonal to a direction of the depth from the outer surface; and at least one opening in the outer surface, the at least one opening in communication with the at least one lumen such that at least one API loaded into the at least one lumen can be absorbed from the at least one lumen into the tissue, where the width of the at least one opening is less than the width of the at least one lumen.
Absstract of: CN120712122A
A drug delivery device includes a substrate; and a plurality of tissue penetrating members 3D printed onto the substrate and configured to be embedded into tissue, wherein at least one tissue penetrating member of the plurality of tissue penetrating members is configured to anchor the drug delivery device to the tissue; and at least one payload comprising at least one API loaded into at least one of the substrate and the plurality of tissue penetrating members for absorption into the tissue when the at least one tissue penetrating member is embedded in the tissue.
Absstract of: WO2024120583A1
The invention relates to a tool for use as a micromanipulator and to a method for producing the tool. The tool consists of a plurality of parts in the form of - a frame (1) which is oriented along a longitudinal axis (L) and which is arranged as a hollow body around an interior, - at least one manipulator element (2) arranged on a first end face (1.1) of the frame (1), and - at least one actuation element (3) which is arranged on a second end face (1.2) opposite the first end face (1.1) and which is mounted slidably and axially movably in the interior of the frame (1), said parts being connected interlockingly and movably to one another by means of necessary connecting and bearing elements, and the tool being entirely generated by additive manufacture, including all the necessary gaps between the parts movably connected to one another. According to the method, the tool with all its parts and with the gaps between the movable parts is manufactured entirely by additive manufacture in one processing operation.
Absstract of: CN223861105U
本实用新型的目的在于提供一种密孔型锌合金口腔膜，其结构包括：锌合金膜，织物膜，织物膜覆盖在锌合金膜，锌合金膜利用粉末冶金技术成型，可以整体完全降解，还能够有效保持金属对于屏蔽空间的有效支撑，而织物膜具有微纳级孔隙率，与锌合金的密孔部分组成多级孔隙结构，增加了与营养物质的交换面积，克服了营养物质无法穿过金属膜的问题。
Absstract of: AU2024276549A1
Methods of manufacturing a porous device for diffusing a fragrance using additive manufacturing including iteratively spreading a loose powder and selecting at least one process parameter to create a porosity within the porous device adapted to carry the fragrance from a fragrance reservoir to an exterior surface of the porous device. An additively manufactured device for diffusing a fragrance includes a diffuser having a plurality of pores defining a porosity of the diffuser, the porosity defining at least one of a rate of absorption, an amount of storage, and a rate of diffusion of the fragrance. A method of using a porous device includes filling the plurality of pores with fragrance and diffusing the fragrance from an exterior surface.
Absstract of: CN121445530A
本发明一种增材制造的空心髋臼杯假体及其制作方法涉及人工髋关节假体技术领域，包括依次连接的堵销、杯体以及多孔结构；杯体的内型面包括内端面、内球面、锥面、防旋凸耳安装槽和卡合槽，杯体的内型面用于安装臼衬；杯体的锥面被用于安装陶瓷衬，而内端面、内球面、防旋凸耳安装槽和卡合槽不与陶瓷衬接触；多孔结构附着在杯体的外型面上，其外型面呈半球形或半椭球形，止于长轴；多孔结构与杯体回转轴为短半轴；杯体的顶端设有一个用于术中安装的螺纹孔，杯体的端面上设有至少一个排粉孔并在排粉后安装堵销；杯体的内球面处不设置或设有至少一个用于安装植入初期固定的钛钉的钛钉孔；端面与外型面之间设有连通的空腔。
Absstract of: JP7810304B1
【課題】本開示は、優れた印刷安定性を保ちつつ、組み合わせる色素の種類によらず耐光性に優れ、かつ広い色域を再現できる錠剤用インクジェットインクセット、錠剤用インクジェットインクのシリーズ、錠剤用混合インクジェットインクおよび錠剤印刷物を提供することを目的とする。【解決手段】本実施形態に係る錠剤用インクジェットインクセットは、可食性の染料と、溶媒として水およびエタノールとを含み、前記染料の種類が互いに異なる複数の錠剤用インクジェットインクを備え、前記複数の錠剤用インクジェットインクのうち少なくとも１つには褪色抑制剤として還元イソマルツロースが含まれており、前記褪色抑制剤を含む前記錠剤用インクジェットインクにおける前記褪色抑制剤の含有量Ｆ［ｗｔ％］と、前記染料の含有量Ｄ［ｗｔ％］との比（Ｆ／Ｄ）が０．２以上３０．０以下の範囲内である。【選択図】図６
Absstract of: CN121445944A
本发明涉及骨修复技术领域，尤其涉及一种骨缺损修复的羟基磷灰石/二氧化锆复合多孔支架的3D打印制备方法、支架和应用。本发明以CT/Micro‑CT重建获得个性化STL，采用高固含光敏陶瓷浆料（HA:ZrO2=25:75～45:55）进行DLP成形；经分段脱脂与分段烧结，在钙磷酸盐/ZrO2界面原位构建连续CaZrO3/或Ca2Zr7O16中间层（覆盖率60%～95%、厚度80～250nm），并保持t‑ZrO₂≥70%。所得TPMS/晶格支架孔隙率45%～70%、连通率≥97%，在多孔条件下仍具抗压≥45MPa、106次疲劳极限≥6MPa；通过受控冷却与SBF预活化可实现HA快速再生（t50≤24h、7d≥2μm）。该方法兼顾个性化成形、界面键合与早期成骨性能。
Absstract of: CN223860972U
本实用新型公开了一种用于3D打印骨填充物的调整装置，涉及医疗器械技术领域。该一种用于3D打印骨填充物的调整装置，包括底座，所述底座一侧滑动设置有活动套。该一种用于3D打印骨填充物的调整装置，通过调节活动套和调节头的位置，使夹持机构位于需要连接位置处的正上方，在将桥接棒块固定后，向下压动齿杆，齿杆在压力左右下移动并使桥接棒块接近连接处，在进一步调节活动套与调节头的位置后，继续下压齿杆，由于限位齿轮被卡销阻挡，使得桥接棒块被精确紧密地压在连接处，使得桥接棒块在固定时更加稳定，且方便调节桥接棒块的位置，结构简单，操作方便，提高了手术效率。
Absstract of: CN121447064A
本发明涉及金属增材制造技术领域，具体涉及一种通过多参数协同控制的钴铬合金成型方法及牙科修复体，成型方法包括如下步骤：1)粉末预处理：对钴铬合金粉末进行真空等离子活化得到活化处理的钴铬合金粉末；在活化处理的钴铬合金粉末表面附着纳米氧化物表面修饰剂得到预打印粉末；2)3D打印：在对步骤1)获得的预打印粉末打印过程中，采用梯度能量打印和动态气氛控制，获得钴铬合金成型件。本发明实现金属表面氧化层的精确可控生长，使氧化层厚度稳定在理想范围，以满足金瓷高强度结合的需求。
Absstract of: US2025049723A1
Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt a pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.
Absstract of: US2025367422A1
A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.
Nº publicación: IL325316A 01/02/2026
Applicant:
BELLASENO GMBH [DE]
CHHAYA MOHIT PRASHANT [DE]
BELLASENO GMBH,
CHHAYA Mohit Prashant
Absstract of: TW202510819A
The disclosure provides a 3D tissue reconstruction implant having a hydrophilic implant surface and consisting of a bio-resorbable material, wherein the implant surface is considered hydrophilic when assessed using an ink test following ISO 8296:2003 and adapted to a 3D surface, wherein said ink test comprises incubating the implant for 1 min in a solution consisting of an ink with a surface tension of 72 mN/m and water and wherein after incubation of the implant in said solution an ink colored implant surface is indicative for a hydrophilic implant surface. The disclosure also provides said implant for use in tissue reconstruction, (soft) tissue support, tissue augmentation and/or implant revision and the use of said implant for reconstructing, augmenting and/or revising a tissue and/or supporting a (soft) tissue, respectively, wherein the implant is inserted into a patient. Further the disclosure provides a method of manufacturing a tissue reconstruction implant with a hydrophilic implant surface.
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