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3D bioinprimaketa

Resultados 164 resultados
LastUpdate Última actualización 05/04/2026 [07:15:00]
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MOLECULARLY CLEAVABLE BIOINK FORMULATION

NºPublicación:  US20260071187A1 12/03/2026
Solicitante: 
THE BRIGHAM AND WOMENS HOSPITAL INC [US]
THE BRIGHAM AND WOMEN'S HOSPITAL, INC
US_20260071187_PA

Resumen de: US20260071187A1

A bioink formulation for digital light processing bioprinting comprising a mixture of a biocompatible cleavable polymer precursor, a biocompatible non-cleavable polymer precursor, and a photoinitiator is described. Three-dimensional (3D) objects prepared using these bioink formulations are also described. In addition, a method of 3D bioprinting is described. The method includes providing a bioink formulation in a 3D bioprinter vat; repeatedly photoactivating the biocompatible photoactive polymer precursors in the 3D bioprinter vat on a build plate immersed in the vat to form a 3D bioprinted object comprising polymers having a series of predefined shapes across the vertical direction based on a set of sliced images; and treating the 3D bioprinted object with an agent that cleaves chemical bonds within the cleavable polymer.

ARTICLES INCLUDING A MICROSTRUCTURED CURVED SURFACE, TOOLING ARTICLES, AND METHODS

NºPublicación:  US20260070777A1 12/03/2026
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
Solventum Intellectual Properties Company
US_20260070777_PA

Resumen de: US20260070777A1

The present disclosure provides a microstructured article including a thermoplastic polymer shaped to have a curve. At least a portion of the curve includes a microstructured surface of utilitarian discontinuities and the microstructured surface includes peak structures and adjacent valleys. The peak structures and the curve are formed of a single piece of the thermoplastic polymer. A method of making the microstructured articles is also provided including a) obtaining a tool shaped to include at least one of a protrusion or a concavity; b) disposing a microstructured film on at least a portion of the tool including the protrusion and/or the concavity; and c) thermoforming a single piece of thermoplastic polymer onto the tool to form a microstructured article shaped to include a curve. The curve is an inverse of the protrusion or the concavity of the tool.

PATIENT INTERFACE

NºPublicación:  AU2026201217A1 12/03/2026
Solicitante: 
RESMED PTY LTD
ResMed Pty Ltd
AU_2026201217_A1

Resumen de: AU2026201217A1

A patient interface comprises a support structure and a seal-forming structure. The support structure is arranged to support the sealing portion and is configured to connect to the frame. The sealing portion comprises textile and is attached to the support structure along an outer perimeter of the sealing portion such that in use the sealing portion may be in tension due to reactive stress of the support structure and/or a resilient stretch characteristic of the textile such that the sealing portion exerts a force against the patient’s face. eb e b

ANCHOR FOR USE WITH ORTHODONTIC APPLIANCE

NºPublicación:  WO2026053080A1 12/03/2026
Solicitante: 
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY [US]
SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
WO_2026053080_PA

Resumen de: WO2026053080A1

An anchor for use with an orthodontic appliance is provided. The anchor is configured to be coupled to an anchor surface defining a reference plane. The anchor includes a base configured to be coupled to the anchor surface, such that the reference plane interfaces with the base. The anchor further includes a hook portion extending from the base and curving towards the reference plane. The hook portion includes a tip distal to the base. The hook portion defines a pocket having a minimum width relative to the reference plane. A maximum distance between the tip and the reference plane is less than the minimum width of the pocket.

分解性ポリ乳酸ポリマーブレンドを含む方法及び組成物

NºPublicación:  JP2026042777A 11/03/2026
Solicitante: 
ポリ-メッドインコーポレイテッド
JP_2026042777_PA

Resumen de: US2023139077A1

Disclosed herein polylactide polymer blend compositions, and methods of making and using such compositions.

DESIGN METHOD OF TRANSPARENT ORTHODONTIC DEVICE AND ATTACHMENT FOR ORTHODONTICS

NºPublicación:  EP4706587A1 11/03/2026
Solicitante: 
ODS CO LTD [KR]
ODS Co. Ltd
EP_4706587_A1

Resumen de: EP4706587A1

The method for designing a transparent orthodontic appliance and attachment for tooth alignment according to the present invention has been devised to solve the above technical problems. It is a method for designing an orthodontic appliance using a computer, comprising: a step (S01) of designing the shape of an attachment to be affixed to the surface of a tooth model; a step (S02) of designing the inner surface shape of the transparent orthodontic appliance corresponding to the attachment designed in step S01; and a step (S03) of outputting the transparent orthodontic appliance by means of a 3D printer. The attachment comprises: two pressure surfaces (101) formed to face each other; two inclined surfaces (201) formed to be inclined toward each other while contacting the two pressure surfaces (101); a top surface (301) contacting the edges of the two pressure surfaces (101) and the two inclined surfaces (201); and an attachment surface (401) affixed to the surface of a tooth. This configuration serves as the technical means for solving the problem.

RADICALLY POLYMERISABLE COMPOUND AND COMPOSITION

NºPublicación:  EP4705279A1 11/03/2026
Solicitante: 
MUEHLBAUER TECH GMBH [DE]
M\u00FChlbauer Technology GmbH
DE_102023111186_PA

Resumen de: WO2024227533A1

The invention relates to a radically polymerisable compound represented by a structure of formula 1: PG-Sp-PCA-Sp- OG (O) NH-K-NHC (O) O-Sp-PCA-Spn-PG (formula 1), wherein PG = in each case independently selected from a radically polymerisable group, R1 = selected from hydrogen, a C1-C8 alkyl group, an aryl group and an araliphatic group having C6-C8 carbon atoms, R2 = selected from hydrogen, a C1-C4 alkyl group; Sp = in each case independently of one another a spacer group selected from unbranched and branched alkylene with C1-C19 carbon atoms, which may additionally contain oxygen, sulfur and/or -OOC- in the carbon chain, or Sp is absent; PCA = in each case independently of one another a polycyclic group; K = an aliphatic acyclic, saturated or unsaturated unit having C1-C15 carbon atoms, an aliphatic cyclic, saturated or unsaturated unit having C3-C15 carbon atoms, or an aromatic or araliphatic unit having C6-C14 carbon atoms; n = 1 to 9. The invention also relates to a process for preparing such a compound, a radically polymerisable composition containing such a compound, the use thereof and a cured dental material.

SEMICRYSTALLINE SULFUR CONTAINING POLYMERS FOR ORTHODONTIC APPLICATIONS

NºPublicación:  EP4704757A1 11/03/2026
Solicitante: 
ALIGN TECHNOLOGY INC [US]
Align Technology, Inc
CN_121358431_PA

Resumen de: US2025009476A1

The present disclosure provides polymeric materials comprising semicrystalline sulfur-containing polymers, methods and curable compositions for making the same, and orthodontic appliances made from said polymeric materials.

METHOD FOR MANUFACTURING ORTHODONTIC DEVICE BY USING INSERTION PATH

NºPublicación:  EP4706586A1 11/03/2026
Solicitante: 
ODS CO LTD [KR]
ODS Co. Ltd
EP_4706586_A1

Resumen de: EP4706586A1

The present invention relates to a program for designing an orthodontic appliance. The method comprises: displaying, on a screen, the insertion path for determining the insertion direction of the appliance (S01); designating a tooth targeted for the insertion path setting (S02); setting the insertion path for the designated tooth in an arbitrary direction (S03); displaying, on the screen, undercuts of each tooth caused by the set insertion path (S04); calculating and storing depth values of the undercuts for each tooth (S05); and calculating and storing the total sum of undercut volumes for each tooth according to the insertion path (S06).

Scanning and printing calibration tool

NºPublicación:  USD1117772S 10/03/2026
Solicitante: 
SHIM MI YOUNG [KR]
PARK JUNE BEOM [KR]
Shim Mi Young,
Park June Beom
US_D1117772_S

Resumen de: JP2024160362A

To provide a dentition phantom model capable of precisely evaluating scanning accuracy of a scanner.SOLUTION: A dentition phantom model 100 includes a base layer composed of a first base layer 110 and a second base layer 120, and a dentition layer 130 disposed on the base layer and including a tooth model, where the tooth model is configured so that a shape observed from one direction is different respectively from shapes observed from the remaining other directions.SELECTED DRAWING: Figure 1aa

PROCESS FOR THE PRODUCTION OF CERAMIC AND GLASS-CERAMIC DENTAL RESTORATIONS

NºPublicación:  KR20260032884A 10/03/2026
Solicitante: 
이보클라비바덴트아게
KR_20260032884_PA

Resumen de: US20260060781A1

Method for producing an all-ceramic dental restoration with a one-piece core and a shell structure, in which a digital construction model of the dental restoration is constructed, the CAD data set obtained is then divided into at least two separate CAD partial data sets. One partial data set defines the contour of the core structure and a second partial data set defines the contour of the shell structure. A green body of the core structure is produced by the first CAD partial data set and a green body of the shell structure of the restoration is produced by the second CAD partial data set. The core and shell structure are then joined together in the green state. The green body is then subjected to heat treatment to remove the binder and the component is then sintered to obtain the finished dental restoration.

一种3D打印颌骨生物支架

NºPublicación:  CN121622995A 10/03/2026
Solicitante: 
中南大学湘雅二医院
CN_121622995_PA

Resumen de: CN121622995A

本发明提供了一种3D打印颌骨生物支架,利用3D打印技术成功构建了负载颌骨BMSCs与牙髓dECM生物支架,同步满足颌骨缺损修复对机械支撑强度、生物活性微环境、成骨仿生诱导特性及免疫调控能力的核心需求。

心电图机及心电图机的打印控制方法

NºPublicación:  CN121622054A 10/03/2026
Solicitante: 
深圳迈瑞生物医疗电子股份有限公司
CN_121622054_PA

Resumen de: CN121622054A

本申请实施例提供了一种心电图机及心电图机的打印控制方法,包括:打印机构,包括包含第一加热点和第二加热点在内的多个加热点;驱动机构,用于驱动目标纸张和打印机构相对移动;控制器,用于:根据第一心电波形数据控制打印机构在第一目标纸张打印至少部分以第一预定布局排布的第一心电图报告,第一加热点用以生成其中的第一基线;根据第二心电波形数据控制打印机构在第二目标纸张打印至少部分以第二预定布局排布的第二心电图报告,第二加热点用于以生成其中的第二基线;第一心电波形和第二心电波形分别位于第一预定布局和第二预定布局二者布局相同的区域,以显著减少部分加热点的加热次数,进而提升心电图机中打印功能模块的使用寿命。

一种三维水凝胶支架及其制备方法和骨修复应用

NºPublicación:  CN121623010A 10/03/2026
Solicitante: 
深圳大学
CN_121623010_PA

Resumen de: CN121623010A

本发明涉及医用生物材料技术领域,尤其涉及一种三维水凝胶支架及其制备方法和骨修复应用。所述三维水凝胶支架为通过若干水凝胶管搭建的层叠的、三维有序结构,每层包括平行间隔排列的多根水凝胶管,相邻两层的水凝胶管之间呈夹角,所述三维水凝胶支架的组分包括海藻酸钠;在三维水凝胶支架中,每根水凝胶管之间具有大孔,每根水凝胶管内部具有全连通微通道,每根水凝胶管的外表面和内表面都具有表面取向性纳米纤维结构。本发明的三维水凝胶支架能很好的应用于骨修复方面,并且本发明利用3D打印、不均匀的交联和拉伸干燥联合技术成功构建了三维水凝胶支架,制备工艺简单准确,易于操作,有利于工业推广和应用。

一种医疗设备

NºPublicación:  CN121622053A 10/03/2026
Solicitante: 
深圳迈瑞生物医疗电子股份有限公司
CN_121622053_PA

Resumen de: CN121622053A

本发明提供了一种医疗设备,涉及具有纸张打印功能的医疗设备领域,包括主机和纸仓;纸仓包括纸仓壳体和纸辊,纸仓壳体上设有纸张放置空间,纸辊转动装配在纸仓壳体上;主机包括主机壳体、打印模块和限位部件;主机壳体上设有纸仓安装腔,在纸仓完全装入纸仓安装腔后,纸仓安装腔具有对应于顶部仓口的顶侧和与顶侧相对的底侧;打印模块具有打印部,限位部件设置在纸仓安装腔的顶侧,限位部件包括凸起部位,凸起部位朝向纸张放置空间凸出以限制打印纸的活动空间,在垂直于纸仓底面的方向上,凸起部位相对于打印部更靠近纸仓的底面。本发明能够降低医疗设备在打印过程中卡纸问题发生的概率。

一种防移位锁定加压接骨板及其制备方法

NºPublicación:  CN121622217A 10/03/2026
Solicitante: 
常州市武进人民医院(常州市第八人民医院)
CN_121622217_A

Resumen de: CN121622217A

本发明公开了一种防移位锁定加压接骨板及其制备方法,属于医疗器械技术领域。所述接骨板包括:具有解剖曲度的主体;设置在主体骨干对应区的梯度多孔结构区域,其孔隙率自中轴向两侧梯度降低,以优化力学匹配、促进骨长入;沿板体排列的多功能复合孔组,每组包含一个锁定孔和一个带倾斜加压滑道的动态加压孔;以及设于板体两端的T形定位槽与遍布骨接触面的微观防滑纹理构成的防移位锚定结构,确保术中瞬时定位与术后抗微动稳定。其制备方法基于患者医学影像进行参数化设计与有限元优化,并采用选区激光熔化技术一体成型。本发明有效解决了传统接骨板应力遮挡、术后移位与骨整合不足的临床问题,显著提升了固定效果与愈合质量。

一种具有结肠靶向功能的淀粉-鱼油复合3D打印凝胶糖果及其制备方法

NºPublicación:  CN121621425A 10/03/2026
Solicitante: 
浙江工业大学
CN_121621425_A

Resumen de: CN121621425A

本发明公开了一种具有结肠靶向功能的淀粉‑鱼油复合3D打印凝胶糖果及其制备方法。通过脉冲电场‑微波协同预处理技术优化淀粉分子结构,结合微射流纳米化与动态超高压均质实现鱼油在淀粉基质中的高效复合与稳态化包埋,再经喷雾冷冻‑真空冷冻干燥技术构建多孔微球载体。最后,将所得微球粉末与特定亲水胶体复配成打印墨水,通过超声多段式辅助3D打印技术精准成型。本发明所制备的凝胶糖果兼具优异的抗氧化性与抗消化特性其鱼油释放率与淀粉水解率低。该产品具有结肠靶向释放功能,在结肠中发挥良好的肠道菌群调节功能,体外发酵总短链脂肪酸含量高,并能显著提升双歧杆菌与乳酸杆菌的相对丰度。

一种基于丝素蛋白的生物3D智能响应支架及其制备方法和应用

NºPublicación:  CN121622997A 10/03/2026
Solicitante: 
广西璟炜生物技术有限公司
CN_121622997_A

Resumen de: CN121622997A

本发明涉及生物支架技术领域,具体涉及一种基于丝素蛋白的生物3D智能响应支架及其制备方法和应用,本发明的生物3D智能响应支架采用定向纤维膜、多孔海绵层和界面层三层仿生梯度结构,模拟天然组织,分别提供力学引导、细胞栖息与生物活性界面,协同促进血管、神经、皮肤的高质量再生。本发明具有pH/酶/温度三重响应单元,能感知病变微环境并触发靶向释放,可解决了传统物理载药突释率高的问题,实现按需精准给药。本发明采用SF/HPMC凝胶进行3D打印,打印精度高,使得本发明孔隙率差异<2%,产品性能稳定,孔隙结构可以根据不同组织(如血管、神经、皮肤)的再生需求进行精确设计和定制。

基于喷墨打印的柔性流体传感系统及其制备方法

NºPublicación:  CN121633193A 10/03/2026
Solicitante: 
季华实验室
CN_121633193_PA

Resumen de: CN121633193A

本申请涉及传感器技术领域,本申请提供一种基于喷墨打印的柔性流体传感系统及其制备方法,其传感系统包括柔性基板以及设置于所述柔性基板上的能量采集天线、能量管理单元、微流控传感器、微泵和信号调制单元,通过设置能量采集天线和能量管理单元,系统能够从环境中自主采集射频能量并转换为电能,为整个系统进行供电,并且能够将采集到的分散能量存储起来,并在需要时提供瞬时高功率输出,摆脱了对传统电池或外接电源的依赖。

一种牙科活动修复体及其制备方法、以及钴铬钼合金粉末

NºPublicación:  CN121624457A 10/03/2026
Solicitante: 
成都科宁达材料有限公司
CN_121624457_PA

Resumen de: CN121624457A

本申请涉及生物医疗材料领域,具体公开了一种牙科活动修复体及其制备方法、以及钴铬钼合金粉末。该牙科活动修复体是以钴铬钼合金为原料,由激光选区熔化技术成形;钴铬钼合金按重量百分比计由以下元素组成:Cr 26~30%,Mo 4~7%,Si 0.5~1.5%,B 0.01%~0.05%,余量为Co及不可避免的杂质;其中,所述钴铬钼合金中不包含W和Ta,且不可避免的杂质总量低于0.5%。其制备方法包括合金熔炼与雾化制粉、筛分干燥、激光选区熔化(SLM)成形及去应力退火。本发明的核心在于通过添加微量硼元素并优化合金组分,使3D打印成形的牙科活动修复体(如支架、卡环)在950~1000℃的常规去应力退火后,即可获得断后伸长率不低于20%、抗拉强度不低于1000 MPa的高塑性及高强度结合。

一种基于人工智能的人工关节假体制造系统

NºPublicación:  CN121638130A 10/03/2026
Solicitante: 
中国人民解放军总医院第四医学中心
CN_121638130_PA

Resumen de: CN121638130A

本发明涉及骨科植入医疗器械制造技术领域,公开了一种基于人工智能的人工关节假体制造系统,包括流体动力学逆向解析单元及拓扑结构逻辑生成单元,构建与多相流瞬态压力场映射的变刚度过滤晶格,在高压冲击核心区生成由截面惯性矩逆向配置的弹性微梁单元,并建立压强响应形变机制,最终输出一体化成型的增材制造指令,本发明利用金属弹性模量与微观拓扑的力学耦合,实现低压下微孔拦截微粒与高压下弹性扩孔瞬态泄压的自适应切换,提升静态植入物原位流体调节功能,避免植入过程中的脂肪栓塞风险。

一种可控光热-酶促降解多孔材料及其制备方法和应用

NºPublicación:  CN121628208A 10/03/2026
Solicitante: 
深圳南科新材科技有限公司
CN_121628208_PA

Resumen de: CN121628208A

本发明提供一种可控光热‑酶促降解多孔材料及其制备方法和应用,所述可控光热‑酶促降解多孔材料的制备原料包括油相混合物和水相混合物;所述油相混合物包括酶敏感聚合物基材、无规杂聚物(RHP)‑酶复合物、Janus光热纳米颗粒、内相分散剂和溶剂;所述水相混合物包括水、电解质和海藻酸盐。本发明提供的多孔材料,通过将Janus光热纳米颗粒与RHP‑酶复合物耦合,在近红外光下,会触发RHP构象变化释放BC脂肪酶,在37℃的温和条件下即可触发多孔材料的降解,48h降解率可达到98%。

一种用于多细胞互作和神经化骨再生的多级结构生物活性三维支架及其制备方法和应用

NºPublicación:  CN121622980A 10/03/2026
Solicitante: 
中国科学院上海硅酸盐研究所
CN_121622980_PA

Resumen de: CN121622980A

本发明涉及一种用于多细胞互作和神经化骨再生的多级结构生物活性三维支架及其制备方法和应用。所述多级结构生物活性三维支架包括:具有宏观通道结构的生物活性支架基体,以及填充在所述基体内部的微观定向拓扑结构;所述宏观通道结构具有三维可控的多样结构,所述微观定向拓扑结构为填充在内部的定向微米级通道;本发明提供的多级结构生物活性三维支架可作为协调多细胞时空相互作用的“空间桥梁”,对于多种细胞在三维空间上的相互迁移、能量代谢水平和特异性分化行为具有有益促进作用;本发明构建多级结构生物活性三维支架是一种兼具多级结构和生物活性的新型的骨修复生物材料,为大段骨修复及其他复杂组织重建提供了一种新策略。

一种超弹低模量抗菌骨植入体的制备方法

NºPublicación:  CN121624446A 10/03/2026
Solicitante: 
昆明理工大学
CN_121624446_PA

Resumen de: CN121624446A

本发明涉及生物医用材料技术领域,具体涉及一种超弹低模量抗菌骨植入体的制备方法,首先基于三周期极小曲面(Gyroid)设计特定孔隙参数的多孔结构模型,然后将NiTi合金粉末与少量Ag粉末均匀混合,最后在保护气氛下采用优化的激光粉末床熔融工艺参数一体化成形。所制备的骨植入体具有1.5‑3.5GPa的低弹性模量,能与人体骨骼良好匹配,显著降低应力屏蔽效应;同时保留了NiTi合金的超弹性,并在4%应变下具有可恢复变形能力。此外,Ag元素的添加使植入体对金黄色葡萄球菌和大肠杆菌的抗菌率均超过90%,在不过度改变基体组织的前提下赋予了材料优异的抗菌性能,有效提升了植入体的临床安全性与服役可靠性。

载药血管支架及其制备方法

Nº publicación: CN121623023A 10/03/2026

Solicitante:

西安马克医疗科技有限公司

CN_121623023_A

Resumen de: CN121623023A

本申请提供了一种载药血管支架及其制备方法,其中,所述载药血管支架的制备方法,包括:制备载药微球;其中,所述载药微球包括负载消炎药物的壳聚糖纳米粒、包覆所述壳聚糖纳米粒的抗菌药物层,以及包覆所述抗菌药物层的PLGA壳层;将所述载药微球与PLGA微球混合制备为共混线材;根据数字模型将所述共混线材经3D打印成型为载药血管支架。

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