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LastUpdate Updated on 05/04/2026 [07:10:00]
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ORGANIC COMPOSITIONS TO TREAT KRAS-RELATED DISEASES

Publication No.:  US20260069625A1 12/03/2026
Applicant: 
ARROWHEAD PHARMACEUTICALS INC [US]
Arrowhead Pharmaceuticals, Inc
US_20260069625_A1

Absstract of: US20260069625A1

The present disclosure relates to RNAi agents useful in methods of treating KRAS-related diseases such as a proliferative disease, including without limitation a solid or liquid cancer, adenocarcinoma, colorectal cancer, advanced and/or metastatic colorectal cancer, colon cancer, lung, non-small cell lung cancer and lung adenocarcinoma, acute myelogenous lung, bladder, brain, breast, cervical, endometrial, gastric, head and neck, kidney, leukemia, myelodysplastic syndrome, myeloid leukemia, liver, melanoma, ovarian, pancreatic, prostate, testicular, thyroid cancers, and cardio-facio-cutaneous (CFC) syndrome and Noonan syndrome, and similar and related diseases, using a therapeutically effective amount of a RNAi agent to KRAS.

Pharmaceutical Combinations For The Treatment Of Cancer

Publication No.:  US20260069567A1 12/03/2026
Applicant: 
PRESAGE BIOSCIENCES INC [US]
Presage Biosciences, Inc
US_20260069567_PA

Absstract of: US20260069567A1

The disclosure herein provides combination therapies for the treatment of cancers such as Leukemia, lymphoma and triple negative breast cancer. The disclosure provides combination therapies of CDK inhibitors, e.g., a CDK inhibitor represented by Formula I:or a pharmaceutically acceptable salt thereof together with a BCL-2 inhibitor or proteasome inhibitor for the treatment of cancer.

METHODS OF TREATING CHRONIC MYELOID LEUKEMIA USING THE TYROSINE KINASE INHIBITOR VODOBATINIB

Publication No.:  US20260069584A1 12/03/2026
Applicant: 
SUN PHARMA ADVANCED RES COMPANY LTD [IN]
Sun Pharma Advanced Research Company Ltd
US_20260069584_PA

Absstract of: US20260069584A1

The present invention relates to methods of treating leukemia using Tyrosine Kinase inhibitors. The invention particularly relates to methods of treating CML and ALL using a compound of Formula I or a pharmaceutically acceptable salt thereof. The compound of Formula 1 has been shown to be efficacious safe and tolerable at a dose from 10 mg to 210 mg.

ANTI-TUMOR COMBINATION THERAPY COMPRISING ANTI-CD19 ANTIBODY AND GAMMA DELTA T-CELLS

Publication No.:  EP4706673A2 11/03/2026
Applicant: 
INCYTE CORP [US]
Incyte Corporation
EP_4706673_PA

Absstract of: EP4706673A2

The present disclosure is directed to a combination therapy comprising an anti-CD19 antibody or antibody fragment thereof and gamma delta T-cells (γδ T-cells) for use in the treatment of leukemia or lymphoma.

SMALL MOLECULE TRAIL GENE INDUCTION BY NORMAL AND TUMOR CELLS AS AN ANTICANCER THERAPY

Publication No.:  EP4706682A2 11/03/2026
Applicant: 
PENN STATE RES FOUND [US]
The Penn State Research Foundation
EP_4706682_PA

Absstract of: EP4706682A2

A pharmaceutical composition, comprising the compound NSC350625, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, for use in a method of treating CNS cancer, lung cancer or lymphoma in a subject.

ANAPLASTIC LYMPHOMA KINASE (ALK) SPECIFIC T CELL RECEPTORS AND METHODS OF USE THEREOF

Publication No.:  EP4704864A2 11/03/2026
Applicant: 
CHILDRENS MEDICAL CT CORP [US]
The Children's Medical Center Corporation
US_20260049279_PA

Absstract of: US20260049279A1

The invention features polypeptides and/or transgenic effector cells including T cell receptors (TCRs) which specifically bind anaplastic lymphoma kinase (ALK) antigens or peptide sequences, and the use of such polypeptides and/or transgenic effector cells and TCRs specific to anaplastic lymphoma kinase (ALK) antigens or peptide sequences in compositions and methods for treating ALK-positive neoplasias such as Non-Small Cell Lung Cancers (NSCLCs).

Composition for Prevention or Treatment of Leukemia

Nº publicación: KR20260031469A 09/03/2026

Applicant:

충남대학교산학협력단충남대학교병원

KR_20260031469_PA

Absstract of: KR20260031469A

본 발명은 나프토퀴논의 구조적 특성을 기반으로 한 신규한 화합물을 유효성분으로 함유하는 항암 조성물에 관한 것으로서, 보다 상세하게는 하기 화학식 (I)로 표시되는 화합물을 포함하는 암 예방 또는 치료용 조성물에 관한 것이다. JPEGpat00004.jpg37103 화학식 (I).

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