Alerta

STRUCTURE-FUNCTION CORRELATIONS IN GEOGRAPHIC ATROPHY (GA) TO PREDICT VISUAL FUNCTION USING AI-BASED RETINAL LAYERS LOSS MEASUREMENTS ON OPTICAL COHERENCE TOMOGRAPHY (OCT)

Absstract of: WO2026231973A1

Systems and methods for predicting geographic atrophy (GA) progression and/or visual function. A set of optical coherence tomography (OCT) volumes for a retina of a subject is received. A set of segmented volumes corresponding to the OCT volumes is generated via a retinal segmentation model, wherein each segmented volume comprises a set of three-dimensional (3D) segments. A set of map outputs is generated by one or more processors, wherein the set of map outputs comprises a map output for each 3D segment of the plurality of 3D segments. A set of biomarker values for a set of spatial biomarker features associated with areas of the map output is computed by the one or more processors for each map output of the set of map outputs, wherein each spatial biomarker feature of the set of spatial biomarker features corresponds to the 3D segment in the map output. A visual function output is computed using the set of biomarker values.

TESTING SYSTEM FOR BALANCE ASSESSMENT

Absstract of: WO2026231111A1

A testing system for performing a balance assessment of a subject can include an inertial measurement unit (IMU) configured to detect movement of the subject along 6 axes, a computing device comprising a camera positioned to capture video of the subject, the computing device configured to communicate with the IMU and having software programmed to: (1) collect raw data, the raw data comprising subject movement data from the IMU and video, (2) after the balance assessment is completed, post-process the raw data by applying machine learning heuristics to the raw data to generate a 3D skeletal model, (3) compare at least one of the raw data and post-processed data from the current assessment to data from another assessment in a side-by-side viewer, and (4) provide an initial assessment of the subject's ability to return to activity based on analysis of the data by an algorithm using machine learning heuristics.

BIOPRINTING

Absstract of: WO2026232073A1

Provided herein are devices, systems, and methods for making an object by additive manufacturing.

PORTABLE NEONATAL INTENSIVE CARE UNIT

Absstract of: WO2026231822A1

An artificial intelligence–based monitoring and healthcare system is disclosed for continuous, multimodal assessment of patient health in real time. The system integrates data from a plurality of sensors, including video, audio, and physiological sensors, to capture vital signs, biosignals, and behavioral cues. Sensor data is preprocessed, feature‑extracted, and in some embodiments, fused into a unified latent representation. The artificial intelligence system supports multiple task‑specific inference operations, including clinical state classification, forward‑looking symptom prediction, and generation of an overall patient condition score. Outputs are further processed using medical pattern recognition and rule‑based logic to enable alerts, reports, and feedback actions, including escalation of care, automated interventions, and telehealth communication between caregivers and medical professionals. The system supports longitudinal monitoring, patient‑specific analytics, and predictive decision support, particularly suited for home‑based care environments.

PORTABLE SOUND THERAPY BOOTH WITH INTEGRATED BIOMETRIC MONITORING

Absstract of: US20260345945A1

0000 An apparatus may comprise a portable booth comprising a weatherproof exterior shell, a modular frame, and antimicrobial interior surfaces. A sound system, a visual display system, a haptic transducer array, and an ambient lighting system may be disposed within the booth and configured to deliver therapeutic audio content, relaxation imagery, vibrotactile stimulation, and chromatic light output across four sensory channels simultaneously. A contactless biometric sensing array may collect physiological data from a user without physical contact. An automated sanitization system may activate upon booth vacancy, comprising at least one of an ultraviolet light emitter and a sanitizing mist dispenser. A controller may receive the physiological data, determine stress indicators, select therapeutic content, and dynamically adjust delivery in real time. The haptic transducer array may operate in a bilateral alternating stimulation pattern synchronized with the audio content. Sessions may be configured for two to fifteen minutes in high-ambient-noise occupational environments.

Systems and Methods for Displaying Sensor-Based User Orientation Information

Absstract of: US20260345006A1

0000 A user-wearable sensor device may be configured to be directly or indirectly secured to a user or to an article worn by the user. The user-wearable sensor device may include at least one sensor configured to collect sensor data associated with an orientation of the user, a display unit including at least one LED or other visual indicator, a battery configured to provide power to at least the display unit, and a control system. The control system may be configured to determine the orientation of the user based on sensor data collected by the at least one sensor, maintain the display unit in a deactivated state in the absence of a defined activation input, detect a defined activation input, activate the deactivated display unit in response to detecting the defined activation input, and control the activated display unit based on the determined orientation of the user.

SIMULATION OF OCULAR FLUID FLOW BASED ON DIGITAL TWIN OF EYE

Absstract of: US20260350276A1

0000 A system for simulating ocular fluid flow in an eye of a live patient includes a controller having a processor and tangible, non-transitory memory on which instructions are recorded. The controller is adapted to obtain respective digital images of cadaver eye sections. The controller is adapted to extract respective contours of anatomical structures in the respective digital images. A model of one or more pathways of the ocular fluid flow is generated based in part on the respective digital images. The controller is adapted to obtain patient data of the eye, including imaging data. A digital twin of the eye is generated by morphing the patient data with the model, including matching identifiable structures in the imaging data and the model. The controller is adapted to generate simulated ocular fluid flow for the eye by modeling the ocular fluid flow in the digital twin.

REMOTE MEDICAL DEVICE AUTHENTICATION

Absstract of: US20260351398A1

Certain aspects of the disclosure provide systems and methods for verification of updates to remote medical devices. For example, methods may include obtaining an update to an operational parameter of a medical device, outputting a first code, and obtaining a second code based on the first code and the update to the operational parameter. Based on verification of the second code, the operational parameter may be updated.

FORMULATIONS FOR USE IN ADDITIVE MANUFACTURING, CONTAINING A TETRACYCLINE COMPOUND AS A LIGHT-ABSORBING SUBSTANCE

Absstract of: US20260345862A1

0000 Formulations usable for additive manufacturing of a three-dimensional object featuring, in at least a portion thereof, a biological and/or biocompatible material, which utilize minocycline and/or any other compound that features a tetracycline skeleton, as a photoabsorber, are provided, as well as additive manufacturing processes utilizing same and objects obtainable thereby.

ADJUDICATION ALGORITHM BYPASS CONDITIONS

Absstract of: US20260350440A1

0000 This disclosure describes techniques for bypassing an algorithm configured to determine a likelihood of episode data being a false indication of a cardiac episode. A medical device system includes processing circuitry configured to receive episode data and determine, based on satisfaction of one or more bypass conditions of a set of bypass conditions, whether to bypass the algorithm. Responsive to bypassing the algorithm, the processing circuitry stores the episode data as a true indication of the cardiac episode.

SUBGINGIVAL MEDICAMENT DELIVERY TRAY

Absstract of: US20260345307A1

0000 Oral appliance delivery trays for use in maintaining or improving oral health, particularly the sub-gingival region, are provided. Methods of manufacturing individualized oral appliance delivery trays are provided. Pre-fabricated oral appliance trays including a compound pre-disposed therein are provided. The compositions and methods may be used to maintain or improve oral, periodontal and systemic health or to prevent or slow, periodontal or systemic health issues related to the oral cavity.

INTERVENTION OPERATION ROBOT AND SYSTEM FOR INTERVENTION OPERATION CONTROL

Absstract of: US20260345262A1

The embodiments of the present disclosure provide an intervention operation robot and a system for intervention operation control. The system comprises: an injection auxiliary device configured to assist an injection instrument for injection; an intervention operation robot configured to convey an intervention instrument; an image acquisition device configured to acquire one or more images; and a control device configured to generate one or more control instructions based on feedback information from at least one of the injection auxiliary device, the intervention operation robot, and the image acquisition device, and send the one or more control instructions to at least one of the injection auxiliary device, the intervention operation robot, and the image acquisition device. The intervention operation robot includes an instrument conveying member and a robotic arm.

MOTOR SPEED CONTROL CIRCUITS FOR SURGICAL SYSTEMS

Absstract of: US20260344988A1

0000 Surgical systems are disclosed. Surgical systems can include evacuation systems for evacuating smoke, fluid, and/or particulates from a surgical site. A surgical evacuation system can be intelligent and may include one or more sensors for detecting one or more properties of the surgical system, evacuation system, surgical procedure, surgical site, and/or patient tissue, for example.

ADAPTIVE CONTROL PROGRAM UPDATES FOR SURGICAL HUBS

Absstract of: US20260345256A1

Various analytics systems are disclosed. An analytics system is configured to communicably couple to a plurality of surgical hubs that are controlled by control programs. The analytics system includes a processor and a memory coupled to the processor. The memory stores instructions that, when executed by the processor, cause the analytics system to: receive perioperative data indicative of an operational behavior of the surgical hubs; analyze the perioperative data to determine whether an update condition is satisfied; generate a control program update according to whether the update condition is satisfied; and transmit the control program update to the surgical hubs. The perioperative data includes data detected by the surgical hubs during a surgical procedure. The control program update is configured to alter the manner in which the control programs operate the surgical hubs during a surgical procedure based on the operational behavior.

ULTRASONIC ENERGY DEVICE WHICH VARIES PRESSURE APPLIED BY CLAMP ARM TO PROVIDE THRESHOLD CONTROL PRESSURE AT A CUT PROGRESSION LOCATION

Absstract of: US20260345227A1

0000 Surgical instruments and system and methods for using surgical instruments are disclosed. A surgical instrument comprises an end effector comprising an ultrasonic blade and clamp arm, an ultrasonic transducer, and a control circuit. The ultrasonic transducer ultrasonically oscillates the ultrasonic blade in response to a drive signal from a generator. The end effector receives electrosurgical energy to weld tissue. The control circuit determines a resonant frequency measure indicative of a thermally induced change in resonant frequency and a electrical continuity measure; calculates a weld focal point based on the determined measures, controls closure of the clamp arm to vary a pressure applied by the clamp arm to provide a threshold control pressure to the tissue loaded into the end effector, and maintains a gap between the ultrasonic blade and clamp arm at a point proximal to the proximal end of the tissue. Pressure is varied based on corresponding weld focal point.

TRANSPARENT SUPPORT MEDIUM FOR 3D PRINTING

Absstract of: US20260347763A1

0000 A 3D-printing support medium is provided herein, comprising hybrid calcium-alginate hydrogel particles and a dispersion medium, formulated by combining calcium-alginate and a soluble polymer distinct from alginate, and the dispersion medium contains a minimum of 2 mM gluconate. These hybrid hydrogel particles possess an average size ranging from 0.1 μm to 50 μm, with exceptional homogeneity characterized by a particle size distribution of less than 50% RSD, resulting in a substantially transparent medium to visible light. The support medium is provided in various forms, including drained particles and slurries with different volume ratios of hydrogel particles to the dispersion medium. The process of preparing this support medium involves forming, pulverizing, washing, and contacting the hybrid hydrogel particles with a gluconate solution, ensuring the presence of gluconate within the hydrogel matrix.

Systems And Methods For Managing Surgical Sponges

Absstract of: US20260345280A1

0000 Systems and methods for managing surgical sponges. A dispenser assembly coupled to a main support includes an internal or first storage location to removably receive a carton of sponge sorters, and an external or second storage location to removably support a carton of surgical draping. At least one arm may be supported on the housing and movable between an undeployed position and a deployed position. The arm may include weighing means to measure a weight of the surgical sponge being disposed in a sponge sorter supported by the arm. The arm may be a cantilever and a beam load cell may be disposed within a channel of a beam. A processor may determine fluid weight based on measured weight and dry weight correlated with the surgical sponge being counted out as detected with a data reader. The processor may estimate blood loss to be displayed on a display.

Additive manufacturing based on fluid-fluid interface

Absstract of: AU2026257517A1

This document describes systems and method of embedded printing for additive manufacturing. A print material is printed into a support material. The print material and the support material each have a fluid phase and a solid phase. The print material transitions from the fluid phase to the solid phase based on a fluid-fluid interaction with the support material. One or more parameters of the support material can be adjusted to cause a diffusion rate of the print material into the support material during the fluid-fluid interaction to be less than a threshold value. Multiple print materials can be printed into the support material simultaneously. ct c t

VOIDING DATA LOGGING DEVICE SENSING A FILLING STATE DURING AN ACQUISITION CYCLE

Absstract of: US20260345396A1

0000 Disclosed is a voiding data logging device including a connector to a sensor array with a plurality of sensor areas arranged to sense a filling state of an absorbent material in the vicinity of a corresponding one of said sensor areas and a data processor configured to store acquisition information indicating at least one of said sensor areas to be read out during an acquisition cycle, read out during the acquisition cycle and via the connector at least the one sensor area indicated by the acquisition information when a sensor array is connected, to determine whether the read out sensor area indicates an above-threshold filling state of the absorbent material in the vicinity of the read out sensor area, and to change the acquisition information se to indicate that a previously read out sensor area is not read out during a subsequent acquisition cycle if when above the above-threshold filling state.

INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, AND RECORDING MEDIUM

Absstract of: US20260351373A1

An information processing apparatus includes: a learning information acquiring unit that acquires learning information configured using training data having activity information regarding an activity state of a user and a score regarding a health state of the user; a first activity information acquiring unit that acquires first activity information; a score acquiring unit that acquires a score; a second activity information acquiring unit that acquires second activity information in which a score acquired by applying the learning information thereto is different from the score acquired by the score acquiring unit; and a recommendation information acquiring unit that acquires recommendation information according to a result of a comparison between the first activity information and the second activity information. Accordingly, it is possible to output information regarding user’s health.

METHODS FOR PREDICTABLE ORTHODONTIC TREATMENT

Absstract of: US20260345294A1

0000 A method may include receiving a digital data set representing an initial tooth arrangement of a plurality of teeth. A linear movement may be is determined for repositioning at least one tooth from an initial position and orientation towards a target position and orientation over a plurality of stages, the trajectory may include a first movement velocity along a first directional component and a second movement velocity along a second directional component orthogonal to the first. Upon determining that the first movement velocity is less than a target velocity, the first movement velocity may be increased for a first one or more stages. A treatment plan may be generated to move the at least one tooth at the increased first movement velocity along the first directional component and at the second movement velocity along the second directional component.

COMPOSITIONS AND METHODS FOR OBTAINING SUSPENSION HUMAN INTESTINAL ORGANOIDS HAVING A SEROSAL MESOTHELIAL LAYER

Absstract of: US20260347787A1

0000 The invention disclosed herein generally relates to methods and systems for growing, expanding and/or obtaining human intestinal organoids (HIOs) having a serosal mesothelial layer. In particular, the invention disclosed herein relates to methods and systems for culturing hindgut spheroid tissue in suspension to obtain HIOs having an organized serosal mesothelial layer that is similar to primary human intestinal serosal mesothelium.

INTELLIGENT AROMATHERAPY SYSTEM

Absstract of: US20260345069A1

Intelligent aromatherapy using sensor fusion, artificial intelligence, and a dispenser which diffuses a programmable mixture consisting of a precise combination of a plurality of scents optimized to stimulate or alleviate specific physical or mental conditions. Analysis, diagnosis, prescription, and aromatherapy tailoring are implemented by measuring and deducing the physical state of the subject and tailoring the aromatherapy to mitigate problems identified in the detection phase. Continuous biometric feedback can further provide additional information on the subject's response to the aromatherapy and further tailor the therapy to provide the desired effect.

GENERATION OF SYNTHETIC RADIOLOGICAL IMAGES

Absstract of: US20260345103A1

The present invention relates to the technical field of radiology, and in particular to assisting radiologists in radiological examinations using artificial intelligence methods. The present invention relates to training a machine learning model and using the trained model to predict representations of an examination area after applications of different amounts of contrast agent.

移動設定された歯牙モデルの補正による矯正装置の設計方法

Nº publicación: JP2026537091A 05/11/2026

Applicant:

オーディーエスカンパニーリミテッド

Absstract of: WO2025079952A1

The present invention is a method for designing an orthodontic device by using a computer, comprising the steps of: (S01) displaying a teeth arrangement image; (S02) correcting an arrangement state of teeth in the teeth arrangement image; (S03) correcting the shape of teeth in the teeth arrangement image; (S04) displaying the orthodontic device on a screen according to the corrected teeth arrangement image; and (S05) outputting the orthodontic device by using a 3D printer.