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278
results.
Updated on
13/11/2026 [06:58:00]
Results 75 to 100 of 278
Absstract of: US20260345093A1
A method of preventing presyncope, syncope and falls in a subject for execution by a wearable device that includes one or more processors. The method comprises generating, by one or more biometric sensors of the wearable device, biometric data regarding the subject, wherein the wearable device is configured to attach to an ear of the subject, wherein the wearable device is sized to be less than 20 mm in the longest dimension and is configured to be positioned entirely outside an ear canal of the ear such that the ear canal remains unobstructed during operation, and wherein the one or more biometric sensors are optical sensors configured to target at least one branch of a posterior auricular artery of the subject to monitor at least one biometric parameter of the subject. The method further comprises aggregating and processing, by the one or more processors, the biometric data to produce processed data; analyzing, by the one or more processors, the processed data to detect or predict an event relating to one or more of: poor cerebral blood flow, poor blood pressure, poor blood volume, poor blood oxygenation, presyncope, syncope, and a fall event; and delivering one or more real-time messages to the subject pertaining to the event.
Absstract of: US20260345372A1
A maxillary airway device (10) typically used at least partially to clear an airway (68) of a user (16), to inhibit obstruction of the airway, particularly during sleep, thereby to treat sleeping disorders or conditions associated with restricted airflow. The device (10) includes a maxillary retaining arrangement (12) for releasably retaining the device (10) relative to a maxilla (14) of a person (16). The device (10) also includes at least a first formation (18) extending from or supported by the retaining arrangement (12) and comprising at least a first contact surface (20) configured for operatively contacting at least a first predetermined location (22) on a tongue (24) of the person (16). The first contact surface (20) urges or retains the tongue (24) of the person (16) towards or in a predetermined position.
Absstract of: US20260345299A1
A computer implemented method of generating a dental design comprising the steps of: a) displaying a 2D image of a smile containing at least two teeth; b) displaying a plurality of visual objects, preferably including a lower curve to characterise said teeth; c) performing at least once: i) determining a limited set of parameters for said teeth based on said visual objects; ii) searching and retrieving a limited number of candidate matching teeth from a digital library; iii) proposing or selecting a matching tooth from said candidate matching teeth; vii) displaying the 2D image with an overlay of the proposed or selected matching teeth. Optionally saving the digital design, providing a 3D digital file, producing a physical object. A computer program product is described herein. A method of dental treatment is described herein.
Absstract of: US20260345061A1
0000 A system for early detection of movement instability includes a wearable device affixed to a body part of a subject, featuring at least one electromyography (EMG) sensor for detecting electrical muscle activity and at least one motion sensor for detecting movement. A computing device, communicatively connected to the wearable device, receives EMG data from the EMG sensor and motion data from the motion sensor. The computing device identifies movement instability patterns using a machine-learning model trained on datasets of known stable and unstable muscle activity data and movement patterns. It determines impairment indicators based on the identified movement instability patterns and generates a user interface displaying these indicators. This system facilitates early detection and monitoring of movement instability.
Absstract of: US20260345641A1
The present disclosure relates generally to pharmaceutical compositions comprising cannabidiol (CBD) or a pharmaceutically acceptable salt or derivative thereof, and an acetylcholinesterase inhibitor, and methods for the treatment or prevention of neurodegenerative disorders, dementia, or diseases associated with glutamate-mediated excitotoxicity.
Absstract of: US20260345074A1
A medical system includes a wearable medical device configured to be worn by a patient, remote server(s), and a mobile device. The mobile device includes at least one processor and a display, the at least one processor being configured to establish communication between the mobile device, the wearable medical device, and the remote server(s) when the mobile device is powered on and within a predetermined range of the wearable medical device. The at least one processor is further configured to provide an interactive survey on the display to receive one or more user inputs, update a graphical user interface on the display based on the one or more user inputs, and cause one or more patient engagement features to be displayed on the display. Upon establishing communication between the mobile device, the wearable medical device, and the remote server(s), patient data is transmitted to the remote server(s).
Absstract of: US20260347948A1
0000 Methods for treating and/or assessing a subject having a symptomatic multiple myeloma or a precursor thereof, where the methods involve characterizing a plasma cell dyscrasia (e.g., monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, multiple myeloma, plasma cell leukemia) in a biological sample from a subject as being high, medium, or low risk by assigning to the plasma cell dyscrasia a multiple myeloma (MM)-like score. The methods may involve sequencing DNA from the biological sample using whole-genome sequencing (WGS).
Absstract of: US20260351136A1
Various embodiments of an anatomical model suitable for microsurgical training are disclosed. The anatomical model includes predetermined ergonomic features that accommodate training of a surgical task.
Absstract of: US20260350949A1
The present disclosure relates to a 3D scanner system including an intraoral 3D scanner including: a projector unit including a light source and a pattern generating element for structuring light into a pattern to be projected onto a surface of an object; and two or more cameras configured for acquiring a set of images, which include an image from each camera, each image including an array of pixels having a pixel color. The system further includes one or more processors operatively connected to the scanner and configured for: generating a 3D surface of the object based on the set of images, the 3D surface including a plurality of points/vertices; and generating a refined 3D surface by solving an optimization problem, wherein the points/vertices are repositioned such that, for each point/vertex, a metric based on the difference in the pixel colors associated with that point/vertex, is minimized.
Absstract of: US20260345355A1
0000 A method for determining parameters for fitting a prosthesis on joint of patient, method being wherein it comprises implementation, by data-processing means of server, of steps of: (a) obtaining kinematic model of joint before prosthesis is fitted, referred to as preoperative kinematic model; (b) constructing a kinematic model of joint after prosthesis has been fitted, referred to as postoperative kinematic model, for current values of fitting parameters of prosthesis, by modifying preoperative kinematic model; (c) predicting postoperative values of a set of functional metrics of joint depending on postoperative kinematic model; (d) validating or not current values of fitting parameters of prosthesis depending on predicted postoperative values of the set of functional metrics; (e) if current values of fitting parameters of prosthesis are not validated, modifying current values of fitting parameters of prosthesis, updating postoperative kinematic model, then repeating steps (c) and (d) on basis of updated postoperative kinematic model.
Absstract of: US20260345350A1
The invention relates to a method and a device (100) for manufacturing a prosthesis (10) for a body part of a limb. On the basis of the digital representation of the impaired body part (20) and of the mirrored digital representation of the intact body part, a digital representation of a prosthesis (22) for the impaired body part is created. Consequently, the prosthesis (10) does not have to be designed from scratch, but can instead be based on the shape of the intact body part due to the chirality of limbs. At least one prosthesis (10) for the impaired body part is then manufactured using the digital representation of the prosthesis (22) and a 3D printer (106) with a print resolution of less than 0.1 mm.
Absstract of: US20260351399A1
A medical device troubleshooting system is provided to interact with and assist a user in resolving operational problems with a medical device. The troubleshooting system may detect an operational problem with the medical device and initiate a troubleshooting session to output a series of different tailored prompts for a user to rectify the glitch. The user prompts are selected and presented in an adaptive manner based on patient specific factors. Selection of prompts and prompt presentation may be responsive to user actions, changes in the patient, and/or the condition of the operational problem. The troubleshooting system checks the condition of the operational problem after presentation of each user prompt and determines a next user prompt accordingly, or ends the session. When the operational problem persists after ending of the session, an external support resource may be contacted.
Absstract of: US20260350817A1
A ophthalmologic surgical system configured to enable scanning and imaging of the anatomical and physiological characteristics of the patient's eye via the image processing subsystem; to provide for the production of a surgical plan based on imaging and eye data received from the image processing subsystem; and to provide for accurate surgical guidance that is based on the surgical plans produced by the planning subsystem where such surgical guidance is timely corrected and/or adapted to adjust for movement of the patient's eye in the course of the surgical procedure.
Absstract of: US20260351359A1
0000 A health status platform includes a receiving component that receives a test result a test of a biological sample collected from a human patient. The test result includes an indication of a presence of an infectious disease in the patient, and an identification and a verification of the patient. The platform includes a certificate component that issues a certificate of origin of the biological sample; and a data merging component that cooperates with a venue access manager that controls access to a venue. The data merging component implements a distributed ledger system that stores encrypted test results of the patient and the identification and verification of the patient, and an end-to-end encryption system that receives an encrypted venue access request from a venue access manager, decrypts the access request, determines if an access request is valid, and if valid, provides an encrypted certificate of origin to the venue access manager.
Absstract of: US20260345245A1
Systems and methods for designing and implementing patient-specific surgical procedures and/or medical devices are disclosed. An example method includes obtaining a first multi-dimensional image data of an anatomical region of a patient in a first loading state; determining, from the first multi-dimensional image data, regions corresponding to anatomical elements of a spine; identifying, in each region, a first set of landmarks; obtaining a second multi-dimensional image data of the anatomical region comprising the spine of the patient in a second loading state; identifying a second set of landmarks from the second multi-dimensional image data that map to the first set of landmarks; obtaining an aligned multi-dimensional image data of the patient's spine; generating a design for a medical implant based on spinopelvic parameters measured from the aligned multi-dimensional image data; and causing a medical implant to be manufactured by sending the design for the medical implant to a manufacturing device.
Absstract of: US20260351372A1
0000 A method for coordinating the manufacturing of an expanded cell therapy product for a patient may include receiving a cell order request to expand the cell therapy product for the patient; generating a patient-specific identifier or cell order identifier associated with the cell order request; and initiating a process to expand the cell therapy product from at least some of a solid tumor obtained from the patient. If acceptance parameters for the expansion cell therapy product do not meet certain acceptance criteria at a second time point subsequent to a first time point in the expansion process, it is determined whether re-performing the expansion of the cell therapy product using the cell expansion technique is possible from the first time point based on the acceptance parameters at the second time point. If such re-performing the expansion is possible, patient treatment events that use the expanded cell therapy product are rescheduled.
Absstract of: US20260345869A1
Provided herein are composite scaffold biomaterials including two or more scaffold biomaterial subunits, each including a decellularized plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularized plant or fungal tissue having a 3-dimensional porous structure, the two or more scaffold biomaterial subunits being assembled into the composite scaffold biomaterial and held together via gel casting using a hydrogel glue; via complementary interlocking geometry of the two or more scaffold biomaterial subunits; via guided assembly based biolithography (GAB); via chemical cross-linking; or any combinations thereof. Methods for producing such scaffold biomaterials, as well as methods and uses thereof, are also provided.
Absstract of: US20260345243A1
0000 A method creates a visual simulation of a subject's condition by identifying a plurality of points defining edges of at least one anatomical structure visible in an image of the subject. From the plurality of defined edges, a dead center point of a shape defined by the edges is derived, the dead center point comprising a set of three-dimensional spatial coordinates. Three-dimensional spatial coordinates of each of a plurality of points in a virtual model of a corresponding anatomical structure are manipulated relative to the derived dead center point. The manipulation may comprise translating, pivoting, rotating, or proportionally scaling the three-dimensional spatial coordinates of the plurality of points in the virtual model relative to the derived dead center point. The identifying, deriving, and manipulating may be repeated for one or more other anatomical structures visible in the image of the subject.
Absstract of: WO2026229971A1
Systems and methods for automatically analyzing movements to identify anomalies and incorrect actions. An artificial intelligence-based digital system is provided that can monitor PT exercises. The systems and methods include a scalable solution to detect incorrect actions or anomalies in PT exercises in real time without using manual definitions. Furthermore, the system includes explanations for detected anomalies, enhancing the real-time feedback and adjustment of treatment plans. Providing real-time feedback improves treatment results by ensuring accurate performance of the exercise by the patient. The systems and methods can include extracting skeleton sequences of an exerciser performing an exercise from 2D videos. A neural network classifies the exercise being performed and identifies the side of the body performing the exercise. The exercise performed by the exerciser can be compared to an expert version of the exercise, and anomalies in the exercise performed by the exerciser can be detected.
Absstract of: WO2026229965A1
Systems and methods for automatically analyzing movements to identify anomalies and incorrect actions. An artificial intelligence-based digital system is provided that can monitor exercises and automatically analyze movements to identify both anomalies and incorrect actions. The system includes a mobile device application that can serve as a user interface for the patient, a camera for streaming video of the patient performing the exercise in real-time, and an artificial intelligence-based system to analyze the patient's movements while performing the exercise and provide real time guidance and feedback to the patient. The system includes a video dataset including people performing a set a supported exercises. In some examples, the video dataset can be used to adjust checks of the artificial intelligence system for metric accuracy. The system can be used for physical therapy treatment tracking, ensuring patients are accurately performing exercises.
Absstract of: US20260346476A1
0000 The invention relates to a tool for use as a micromanipulator and to a method for producing the tool. The tool consists of a plurality of parts in the form of—a frame (1) which is oriented along a longitudinal axis (L) and which is arranged as a hollow body around an interior,—at least one manipulator element (2) arranged on a first end face (1.1) of the frame (1), and—at least one actuation element (3) which is arranged on a second end face (1.2) opposite the first end face (1.1) and which is mounted slidably and axially movably in the interior of the frame (1), said parts being connected interlockingly and movably to one another by means of necessary connecting and bearing elements, and the tool being entirely generated by additive manufacture, including all the necessary gaps between the parts movably connected to one another. According to the method, the tool with all its parts and with the gaps between the movable parts is manufactured entirely by additive manufacture in one processing operation.
Absstract of: US20260345298A1
0000 A method of fabricating a removable dental appliance includes the steps of: (a) acquiring 3D digital image data of a patient's mouth and dentition; (b) creating a 3D digital model of a removable dental appliance to be fabricated wherein the 3D digital model incorporates a model clasp and/or model seat selected from a digital library of virtual clasps and/or seats, each of the virtual clasps or seats corresponding to an associated physical clasp or seat; (c) fabricating a portion of the removable dental appliance from the 3D digital model, the portion of the removable dental appliance including an attachment section; (d) selecting a physical clasp or seat that corresponds to the model clasp or seat; and (e) inserting a tail section of a selected physical clasp and/or seat into mounting structure in the attachment section, the tail section being dimensioned to matingly engage the mounting structure.
Absstract of: EP4834276A1
0001 Method (10) for planning a dental treatment on an individual, the method (10) comprising digitally and automatically obtaining (12) a wax-up built based on a determined performance of the jaw function of the individual, the wax-up comprising a proposed position and/or shape of the individual's intraoral structures.
Absstract of: EP4835905A1
Described herein is an artificial intelligence (AI) component configured to take health actions for a user based on user health information from one or more sensors. In some examples, the AI component is an AI agent that receives the health information, provides the health information in a prompt to a large language model (LLM), and takes a health action recommended by the LLM. In further examples, the AI component determines that the user is experiencing a health emergency and, based on the user not responding to the alerting within a time period, on a health emergency type, and on a user location, alerts an emergency service provider or emergency contact. In additional examples, the AI component determines that the user is at health care provider location for a physical examination and provides a health summary for the user generated for a time period since a last physical examination.
Nº publicación: EP4833071A1 04/11/2026
Applicant:
POLBIONICA SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA [PL]
Polbionica spolka z ograniczona odpowiedzialnoscia
Absstract of: WO2025141425A1
A bioprinted liver model with a vascular system consisting of layers and comprising at least one flow channel in which: the first two layers forming the base of the model are 100% filled with bioink, and wherein layer 1 is positioned at an angle of 0° to the flow channel and layer 2 is positioned at an angle of 90° to the flow channel, the inner layers of the model are filled from 20% to 100% with bioink, wherein the inner layers comprise a centrally located at least one flow channel, the perimeter of which is printed with 100% filling and in which every inner layer is arranged at an angle of 60° with respect to the previous layer, the last two layers enclosing the model: the penultimate and the last layer are 100% filled with bioink and wherein the penultimate layer is arranged at an angle of 0° with respect to the flow channel and the last layer is arranged at an angle of 90° with respect to the flow channel, wherein the bioink used is based on natural polymers, synthetic polymers, methacrylated derivatives of natural polymers or mixtures thereof. A method for manufacturing the liver model and the use thereof.
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