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Solicitudes publicadas en los últimos 30 días / Applications published in the last 30 days
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A METHOD AND PRODUCTS FOR SELF-MONITORING THE RISK OF DEVELOPING OR HAVING PREECLAMPSIA

Publication No.:  WO2026171925A1 20/08/2026
Applicant: 
HOFFMANN LA ROCHE [CH]
ROCHE DIAGNOSTICS INT AG [CH]
ROCHE DIAGNOSTICS GMBH [DE]
F. HOFFMANN-LA ROCHE AG
ROCHE DIAGNOSTICS INTERNATIONAL AG
ROCHE DIAGNOSTICS GMBH
WO_2026171925_A1

Absstract of: WO2026171925A1

The present invention relates to a method for self-monitoring a woman being at risk of developing or having preeclampsia, an electronic consumer device configured for use in the method, a computer program and a medical test-kit adapted for the use in the method.

INTEGRATED DECENTRALIZED IDENTITY-BASED SYSTEM FOR WEARABLE BODY-FLUID DETECTION, BIOCHEMICAL ASSAYING, EVIDENCE-CHAIN VERIFICATION, TRIAGE ROUTING, AND LIFELONG HEALTH MANAGEMENT WITH MULTI-MODAL CONFIRMATION

Publication No.:  US20260243768A1 20/08/2026
Applicant: 
BEI FURONG [US]
BEI FURONG
US_20260243768_A1

Absstract of: US20260243768A1

A wearable sensing system converts a home body-fluid sampling event into a clinically usable triage signal. A disposable wearable sensing article includes a directed microfluidic funnel, metering channel, conditioning layer, and biochemical assay core. A mobile module performs optical calibration, executes a stabilization protocol to generate a stability metric, and applies a multi-level quality gate before generating a cryptographically signed Trusted Event Package bound to a decentralized identity. The system routes verified triage outputs to medical endpoints and, when indicated, transmits a Minimum Necessary Emergency Bundle for emergency escalation. First and second embodiments include a nipple-discharge bra-liner and a cervicovaginal pad using consistent terminology and lock points. Exemplary network endpoints include medicalcenter.us, 120.us, bei.app, healthspac.com, medprc.com, beisignal.com, beipanel.com, and beiprint.com.

ECHOCARDIOGRAM CARDIAC MONITORING

Publication No.:  US20260240516A1 20/08/2026
Applicant: 
KONINKLIJKE PHILIPS N V [NL]
KONINKLIJKE PHILIPS N.V.
US_20260240516_A1

Absstract of: US20260240516A1

Proposed concepts aim to provide schemes, solutions, concepts, designs, methods, and systems pertaining to cardiac monitoring of a subject which involves obtaining both echocardiogram data and a cardiac activity signal. In particular, embodiments aim to provide a method of cardiac monitoring in which a cardiac rhythm abnormality value is determined and used to generate supplementary data which can accompany the echocardiogram data to provide a comprehensive view of the cardiac behaviour of the subject during a monitoring time period.

ORTHOPEDIC SURGICAL PLANNING SYSTEM FOR AUTONOMOUS ROBOTIC SURGERY

Publication No.:  WO2026173966A1 20/08/2026
Applicant: 
ZIMMER INC [US]
ZIMMER, INC.
WO_2026173966_A1

Absstract of: WO2026173966A1

Systems and methods may provide orthopedic surgical planning for autonomous robotic surgery. For example, a method can include displaying a user interface including a surgical planning program. The method can include receiving patient information at the surgical planning program, the patient information indicating that a patient has a sagittal plane knee malalignment. The method can include generating, using a machine learning trained model of the surgical planning program, a sagittal plane knee surgical plan based on the patient information, the sagittal plane knee surgical plan being specific to the sagittal plane knee malalignment and including a resection recommendation. The method can include displaying the sagittal plane knee surgical plan on the user interface for use with a robotic arm.

METHODS OF ASSESSING COGNITIVE FUNCTION

Publication No.:  WO2026171828A1 20/08/2026
Applicant: 
HOFFMANN LA ROCHE [CH]
HOFFMANN LA ROCHE [US]
F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.
WO_2026171828_A1

Absstract of: WO2026171828A1

A computer-implemented method of assessing the cognitive function of a subject is described. The method comprises: obtaining subject data that has been collected by carrying out a digital cognitive function test method. The digital cognitive function test method comprises: providing a user interface to the subject; presenting the subject, via the user interface, with a first sequence of images, each image of the first sequence depicting a respective object; receiving, from the subject via the user interface, naming data comprising data indicative of a name attributed by the subject to respective objects in each image of the first sequence; presenting the subject, via the user interface, with a second sequence of images, each image of the second sequence depicting a respective object, wherein the second sequence of images comprises a plurality of images that were previously presented to the subject in the first sequence and a plurality of images that were not previously presented to the subject; and receiving, from the subject via the user interface, image recognition data comprising data indicative of whether the subject identified respective images of the second sequence as being previously presented in the first sequence. Receiving the image recognition data comprises receiving, for each image of the second sequence, a subject selection of one of a plurality of discrete choice indicators including at least one indicator corresponding to the image being an image previously p

Automated Creation of Stimulation Programs for Spinal Cord Stimulation

Publication No.:  US20260241178A1 20/08/2026
Applicant: 
BOSTON SCIENT NEUROMODULATION CORPORATION [US]
Boston Scientific Neuromodulation Corporation
US_20260241178_A1

Absstract of: US20260241178A1

Systems for programming a neurostimulator for providing electrical neurostimulation to treat a patient are described. The systems are configured to allow a user, typically a clinician, to configure a source stimulation program. The system then uses the source program and/or other inputs to suggest additional stimulation programs (i.e., derivative stimulation programs) that may be created and used to program the patient’s neurostimulator. The other inputs may specify information about the patient, the patient's or clinician’s goals and priorities during the programming session, and/or information about the patient's neurostimulator, such as whether the neurostimulator uses a primary cell or rechargeable battery. The system can execute algorithms to use the source program and/or the other inputs to automatically create the derivative stimulation programs and to program the neurostimulator with those programs.

SURGICAL GUIDANCE

Publication No.:  WO2026173885A1 20/08/2026
Applicant: 
PARAGON 28 INC [US]
PARAGON 28, INC.
WO_2026173885_A1

Absstract of: WO2026173885A1

A process to facilitate conformance between planned and actual use of surgical instrumentation includes obtaining a fluoroscopic image of patient anatomy, the fluoroscopic image being captured based on a current placement of physical instrumentation relative to the patient anatomy, the physical instrumentation including at least one fiducial, wherein the fluoroscopic image depicts the patient anatomy and a projection of the at least one fiducial relative to the patient anatomy, importing an instrumentation model that models the physical instrumentation and an anatomy model that models the patient anatomy, registering the instrumentation model and the anatomy model to the fluoroscopic image, and determining, based on the registering, a deviation of the current placement of the physical instrumentation from a planned placement of the physical instrumentation.

SYSTEM AND METHOD OF NEURAL DATA COMPRESSION OF A KINETIC INTELLIGENT WIRELESS IMPLANT

Publication No.:  US20260241169A1 20/08/2026
Applicant: 
GENESIS INTELLIGENCE LLC [US]
Genesis Intelligence, LLC
US_20260241169_A1

Absstract of: US20260241169A1

0000 Embodiments of an implantable system and apparatus for providing electrical and optical deep brain stimulation are disclosed. Through the biological introduction of light-responsive opsins to neurons, the system is operable to transform neurons into optogenetically programmable state and history-dependent logical transformers. Embedded processors of the system are operable to stimulate individual neurons using phase-shifted electrical and/or optical signals through a neural interface comprising a plurality of carbon nanotubes, then electrically and/or optically measure the neurons. Due to the parallelism and chemical superposition of the human brain, the implantable system is operable to establish a quantum-like processing ability using its neural interface.

SYSTEM AND METHOD FOR CLOSED-LOOP BIMODAL NEUROMODULATION BASED ON PHYSIOLOGICAL PARAMETERS

Publication No.:  WO2026172388A1 20/08/2026
Applicant: 
MADAN BHAVYA [IN]
RUSTAGI RIA [IN]
MADAN, Bhavya
RUSTAGI, Ria
WO_2026172388_A1

Absstract of: WO2026172388A1

The present invention discloses a system and a method for closed-loop bimodal neuromodulation based on a plurality of physiological parameters The system comprises a wearable device (100) to be worn on a head. The wearable device (100) integrates electrodes (102) positioned at predefined anatomical landmarks to deliver electrical stimulation, audio transducers (104) aligned with ears to deliver auditory stimulation, physiological sensing elements (106) to acquire physiological signals, detection units (108) to capture motion data, and control units (110) to execute signal conditioning, motion artifact suppression, signal quality evaluation using machine learning, and feature extraction to compute the plurality of physiological parameters. The system performs temporal–spatial feature modelling, cognitive state estimation using machine learning, user feedback integration, and adaptive modulation of electrical and auditory stimulation parameters. The system continuously monitors physiological responses and dynamically adjusts stimulation to guide a user toward a selected cognitive state.

METHODS AND SYSTEMS FOR SCREENING AND MONITORING OF NEURODEGENERATIVE DISEASES

Publication No.:  WO2026172387A1 20/08/2026
Applicant: 
INDIAN INST TECHNOLOGY BOMBAY [IN]
INDIAN INSTITUTE OF TECHNOLOGY BOMBAY
WO_2026172387_A1

Absstract of: WO2026172387A1

Embodiments herein disclose methods and systems for screening and monitoring of neurodegenerative diseases, which consolidates multiple diagnostic functions into a single user-friendly, interactive and personalized platform. Embodiments herein disclose an autonomous interactive gaming system, wherein the systems can capture multi-parameter data, including sensory, cognitive, motor, and posture information, and predict, classify, and identify various neurodegenerative conditions using a multi-variate equation, and machine learning models without clinician intervention. Embodiments herein disclose telemonitoring capabilities that enable clinicians to remotely access and review participant scores and results in real-time.

METHODS FOR PREDICTING GLIOMA DISTANT RECURRENCES ALONG WHITE MATTER TRACTS USING PROBABILISTIC DIFFUSION TRACTOGRAPHY

Publication No.:  WO2026174243A1 20/08/2026
Applicant: 
MEMORIAL SLOAN KETTERING CANCER CENTER [US]
SLOAN KETTERING INST FOR CANCER RESEARCH [US]
MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES [US]
MEMORIAL SLOAN-KETTERING CANCER CENTER
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH
MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES
WO_2026174243_A1

Absstract of: WO2026174243A1

Provided herein are systems and methods for predicting glioma distant recurrences along white matter tracts based on probabilistic diffusion tractography. A computing system may identify, for a subject diagnosed with glioma in a brain, an MRI image of a volume including a primary site corresponding to the glioma in a structure of the brain and a plurality of parameters defining the diffusion of water molecules. The computing system may receive data for defining a region of interest (ROI) in the MRI image corresponding to the primary site associated with the first tumor in the brain. The computing system may generate, by applying a function to the plurality of parameters and the ROI, a map for the volume of the brain of the subject. The map may identify a plurality of streamlines through the structure of the brain and a plurality of values corresponding to the plurality of streamlines.

歯科支援装置、及びこのためのプログラム

Publication No.:  JP7909089B1 20/08/2026
Applicant: 
那須一仁
JP_7909089_B1

Absstract of: JP7909089B1

【課題】補綴物を適切に作ることを可能にする歯科支援装置及びそのためのプログラムを提供する。【解決手段】患者の歯の画像データを取得し、当該画像データに基づいて歯を複数の領域に分割し、各領域ごとの代表色を算出し、予め定められた基準色体系を細分化して得られた基準色候補との色差を算出し、算出された色差に基づいて該患者に適合する補綴物又は矯正シミュレーションのための色を特定する処理を実行する。【選択図】図1

THERMOREGULATED PROSTHETIC LINERS

Publication No.:  WO2026170317A1 20/08/2026
Applicant: 
ETHNOCARE INC [CA]
ETHNOCARE INC.
WO_2026170317_A1

Absstract of: WO2026170317A1

The disclosure discloses prosthetic liners that address breathability and comfort issues while maintaining proper fit and functionality. A prosthetic liner assembly is provided. It includes a prosthetic liner and a skin-proximal interface. The prosthetic liner defines a proximal end and a socket-mounting distal closed end and delimiting a member-receiving cavity. It includes a first lattice structure forming a body region of the prosthetic liner extending from the proximal end toward the distal end, and a second structure forming the distal closed end. The skin-proximal interface is removably insertable into a member-receiving cavity of the the prosthetic liner and includes a fabric body covering at least partially an inner surface of the prosthetic liner delimiting the member-receiving cavity when the skin-proximal interface is inserted into the prosthetic liner.

POROUS NANOFIBER/MICROFIBER SPHERES AND METHODS OF USE THEREOF

Publication No.:  WO2026174041A1 20/08/2026
Applicant: 
UNIV NEBRASKA [US]
BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
WO_2026174041_A1

Absstract of: WO2026174041A1

Porous nanofibrous/microfibrous spheres are provided as well as methods of use thereof and methods of making. In certain embodiments, the method of synthesis comprises a) applying inner air, outer air, and a nanofiber/microfiber suspension to a sphere generator, wherein the nanofiber/microfiber suspension comprises nanofiber/microfiber segments, and b) collecting the spheres from an outlet nozzle of the sphere generator in a media having a temperature of less than about -20°C (e.g., liquid nitrogen), thereby synthesizing the porous nanofibrous/microfibrous spheres.

SHAPE MEMORY POLYURETHANE FOR ORTHODONTIC APPARATUS AND ORTHODONTIC APPARATUS USING THE SAME

Publication No.:  KR20260126220A 20/08/2026
Applicant: 
주식회사월드바이오텍
KR_20260126220_A

Absstract of: KR20260126220A

본 발명은 치아 교정 장치용 형상기억 폴리우레탄 및 이를 이용한 치아 교정 장치에 관한 것으로, 본 발명에 따른 치아 교정 장치용 형상기억 폴리우레탄은 형상기억 성능이 우수하여 치아 교정 장치에 유용하게 사용할 수 있다.

Operationsschablone und Verfahren zur Gestaltung und/oder Herstellung einer Operationsschablone

Publication No.:  DE102025105586A1 20/08/2026
Applicant: 
KARL LEIBINGER ASSET MAN GMBH & CO KG [DE]
Karl Leibinger Asset Management GmbH & Co. KG
DE_102025105586_PA

Absstract of: DE102025105586A1

Die Erfindung betrifft eine Operationsschablone (OS) zur Anwendung im Bereich eines Schläfenbeins, insbesondere im Rahmen einer Durchführung einer radikalen Mastoidektomie, umfassend einen Schablonenkörper (SK) mit einer Außenseite (AS) und einer Innenseite (IS), auf welcher der Schablonenkörper (SK) schläfenbeinseitig aufzulegen ist. Der Schablonenkörper (SK) ist mit einem von der Außenseite (AS) zu der Innenseite (IS) verlaufenden Durchbruch (D) durchsetzt, wobei der Durchbruch (D) bei dem Schablonenkörper (SK) mit einem Außenrand (AR) definiert ist, welcher einer Außenkontur eines zu entfernenden Knochenteils des Schläfenbeins (SB) entspricht.

A SYSTEM AND METHOD FOR ENHANCING PROSTHETIC PRECISION

Publication No.:  WO2026172241A1 20/08/2026
Applicant: 
CHAUDHARY GAURANG [IN]
MENON ARJUN [IN]
TUMPUDI HITESH [IN]
CHAUDHARY, Gaurang
MENON, Arjun
TUMPUDI, Hitesh
WO_2026172241_A1

Absstract of: WO2026172241A1

The present invention relates to a system (100) and method for enhancing prosthetic precision by utilizing advanced computer vision integration for intuitive control of artificial limbs. The system (100) comprises a set of hardware components, at least one actuator motor (102), at least one camera (103), at least one processor (104). The set of hardware components include 3D printed structures (101) which are controlled by the actuator motor (102). The camera (103) is configured to capture one or more images or videos of a surrounding and the images or videos are transmitted to the processor. The processor (104) analyzes the images or videos to detect one or more objects in the images or videos via one or more machine learning protocols. Further the processor (104) sends a signal to the actuator motor (102) and 3D printed structures for grasping the concerned object form the one or more objects. The processor (104) is able to dynamically switch between at least four grasp setups (wrist, with palm grip pronated wrist, with palm grip, tripod grip and pinch grip) depending on the objects detected and a set of user preferences.

BREATHING COMPENSATION FOR CONE BEAM IMAGING AND ELECTRO-MAGNETIC NAVIGATION SYSTEMS

Publication No.:  WO2026173991A1 20/08/2026
Applicant: 
COVIDIEN LP [US]
COVIDIEN LP
WO_2026173991_A1

Absstract of: WO2026173991A1

A system and method for endoluminal navigation including a catheter configured for insertion into a luminal network of a patient, a memory operably connected to a processor, the memory storing instructions that when executed by the processor, detects movement of a catheter sensor associated with a distal portion of the catheter, receives cone-beam computed tomography (CBCT) images of the luminal network, detects, based on information in the CBCT images, movement of a distal portion of the navigation catheter in the CBCT images, generates a catheter movement value, and updates, based on the catheter movement value, a displayed position of a representation of the distal portion of the catheter in a 3D model.

BREAST ULTRASOUND SYSTEM WITH NEEDLE BIOPSY CAPABILITY

Publication No.:  WO2026170304A1 20/08/2026
Applicant: 
UNIV WESTERN ONTARIO [CA]
THE UNIVERSITY OF WESTERN ONTARIO
WO_2026170304_A1

Absstract of: WO2026170304A1

A whole breast 3D ultrasound imaging system has a base configured to be worn by a subject. The base has an annular wall for containing an ultrasound transmission fluid around a breast of a subject, and an edge configured to conform to a body surface around the breast of the subject to reduce leakage of the ultrasound fluid between the edge and the body of the subject. The base has an opposed pair of spaced apart needle guide paddles movable to increase or decrease a distance between the needle guide paddles. At least one of the needle guide paddles has a plurality of through-apertures through each of which a biopsy needle is insertable. An ultrasound compression plate is situated between the needle guide paddles. A motor plate subassembly is releasably mounted on the base, and has an ultrasound transducer movable in a plane parallel to the ultrasound compression plate.

ACTIVITY PREDICTION

Publication No.:  US20260244938A1 20/08/2026
Applicant: 
OK2STANDUP INC [US]
OK2STANDUP, INC.
US_20260244938_A1

Absstract of: US20260244938A1

Systems and techniques for training an activity prediction model and for performing activity prediction utilizing the activity prediction model are described herein. An activity prediction model may be trained by training potential activity prediction models using machine learning based on an input dataset including activity of an individual from a training phase, ground truth dataset and different hyperparameters, performing hyperparameter optimization, and optimizing the potential activity prediction models for accuracy or minimizing loss. Thereafter, the activity prediction model may be utilized by passing an execution dataset including a set of sensor data associated with activity of an individual from an execution phase to generate an activity prediction which may be indicative of a current or future activity of the individual.

ORTHODONTIC APPLIANCE SYSTEMS AND METHODS OF MAKING SAME

Publication No.:  US20260240625A1 20/08/2026
Applicant: 
ORMCO CORP [US]
Ormco Corporation
US_20260240625_A1

Absstract of: US20260240625A1

0000 An orthodontic appliance system for orthodontic treatment of teeth. The system includes a template with a cavity. An attachment is removably received in the receptacle and has a surface including a bonding surface. A method of manufacturing includes constructing a scaffold assembly including a base and placing a template in contact with the scaffold assembly. The method includes inserting the attachment into the receptacle. During separating, the attachment remains coupled to the template in the receptacle. A method of manufacturing includes providing a mold of the patient's teeth. The mold including at least one projection and a through-passage. The method includes placing a container of dental composite in fluid communication with the through-passage, placing a template over the at least one projection, injecting dental composite from the container through the through-passage and into the receptacle, and removing the template from the at least one projection with the filled receptacle.

NOVEL PROCESS

Publication No.:  US20260242736A1 20/08/2026
Applicant: 
NANODENT S R L [IT]
NANODENT S.R.L.
US_20260242736_A1

Absstract of: US20260242736A1

0000 The present invention relates to a process for obtaining a dental prosthesis comprising a crown and tooth root. Said process comprises at least one step of directing undifferentiated cells or keratinocytes and at least one three-dimensional printing step, preferably 3D bioprinting of the dental prosthesis. Furthermore, the invention regards the dental prosthesis obtained With the process and a bioink suitable for three-dimensional printing (3D), preferably suitable for 3D bioprinting.

METHODS AND SYSTEMS FOR CONTROLLING OXYGEN DELIVERY IN A FLOW THERAPY APPARATUS

Publication No.:  AU2026210822A1 20/08/2026
Applicant: 
FISHER & PAYKEL HEALTHCARE LTD
FISHER & PAYKEL HEALTHCARE LIMITED
AU_2026210822_A1

Absstract of: AU2026210822A1

The present disclosure provides for a control system for a flow therapy apparatus. The control system can control delivery of a fraction of delivered oxygen (FdO2) to a patient. The control system can maintain the FdO2 at a target level during a therapy session. The control system can automatically control an oxygen inlet valve in order to control the flow of oxygen to the patient. ul u l

METHODS AND SYSTEMS FOR PREVENTING CARDIOMETABOLIC DISEASES

Publication No.:  US20260245735A1 20/08/2026
Applicant: 
VALIDAE HEALTH L P [US]
Validae Health, L.P.
US_20260245735_A1

Absstract of: US20260245735A1

0000 Some embodiments provide for a method for identifying an intervention for a subject in furtherance of preventing development of cardiovascular disease in the subject, the method comprising: obtaining cardiometabolic health data for the subject; determining, using at least some of the cardiometabolic health data, a first trained machine learning (ML) model and for each of multiple time intervals, one or more measures of risk that the subject develops cardiovascular disease to obtain multiple measures of risk; determining, using the multiple measures of risk that the subject develops cardiovascular disease and at least one second trained ML model, benefit of administering to the subject one or more therapeutic interventions designed to reduce risk of cardiovascular disease by targeting one or more modifiable causes of the cardiovascular disease; and identifying, using the determined benefit of administering the therapeutic intervention(s), at least one therapeutic intervention to recommend being administered to the subject.

SYSTEMS FOR VALIDATING ELECTRICALLY EVOKED COMPOUND ACTION POTENTIAL (ECAP) RECORDINGS

Nº publicación: US20260245680A1 20/08/2026

Applicant:

OHIO STATE INNOVATION FOUND [US]
Ohio State Innovation Foundation

US_20260245680_A1

Absstract of: US20260245680A1

Disclosed herein are systems, methods, and computer-program products for automatically detecting the presence of neural responses and incomplete masking in recordings of the electrically evoked compound action potential (eCAP).

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