Alerta

Method of Determining Risk for Chronic Stress and Stroke

Absstract of: US20260086100A1

0000 Provided are methods of determining risk for chronic stress and stroke. More specifically, provided is an early prognostic index that can be used to predict chronic stress and stroke risk. There is provided a method of evaluating the risk of developing chronic stress and stroke, the method including obtaining a biological sample from an individual; measuring the levels of a set of biomarkers in the biological sample obtained from the individual; measuring the levels of a set of clinical markers of the individual; using a computer to programmatically generate an index based on the levels of biomarker in the biological sample obtained from the individual in combination with levels of the individual's clinical marker; and using the index to identify a likelihood that the individual will experience chronic stress and stroke.

FLUORESCENT CERVICAL CUP FOR UTERINE MANIPULATORS

Absstract of: WO2026060509A1

The present patent of invention relates to the field of medicine and medical devices, and more specifically to an innovative fluorescent cervical cup for use in uterine manipulators during colpotomy surgical procedures. This improved device aims to increase the safety and efficacy of conventional or minimally invasive gynaecological procedures, including laparoscopic, robotic, and endoscopic surgery, particularly under conditions of limited visibility.

TRANSRADIAL PROSTHESIS ASSESSMENT SYSTEM

Absstract of: US20260083576A1

A transradial prosthesis assessment system apparatus and method for simulating and evaluating alignment and functionality of a definitive prosthesis system for a user's diagnostic socket is provided. The apparatus includes socket adaptors, a connector, shaft housings of different sizes, extension shafts of different lengths and wrist adaptors that can be connected through different combinations to provide length and alignment adjustability to emulate the definitive prosthesis.

3D PRINTED SCAFFOLD IMPLANT AND A METHOD FOR MANDIBULAR RECONSTRUCTION

Absstract of: AU2025260012A1

The present invention relates to a 3D scaffold implant system for mandibular reconstruction, featuring a scaffold structure that includes at least four scaffold segments strategically positioned within the implant, the segments ensuring precise placement within a subject's jawbone and facilitate optimal integration with a surrounding bone tissue; a fluid delivery tube system integrated into each of the scaffold segments to administer a growth factor(s) and an antibiotic directly into the scaffold implant; a pump that facilitates controlled delivery of the growth factors into the scaffold segments; at least three fixation that provide stability to the implant and micro-motors that enable precise alignment of the scaffold implant to conform seamlessly to the natural curvature of the jawbone.

WIRELESS DEVICE FINGERPRINTING SYSTEMS AND METHODS

Absstract of: WO2026064678A1

A method includes receiving signals, via a phased antenna array, from at least one signal source, wherein the received signals include noise caused, at least in part, by sound waves near the at least one signal source; locating, via a signal processor, the at least one signal source in three-dimensional (3D) space using the received signals; demodulating the noise in the received signals caused by sound waves near the at least one signal source to produce sound data; identifying at least one user from voice data extracted from the sound data and/or at least one device associated with the at least one signal source to produce identification data; and in response to the received signals, the sound data and/or the identification data satisfying one or more rules in a rule database, executing an action associated with the one or more rules.

僧帽弁のコンピュータ支援設計（ＣＡＤ）モデリングのためのコンピュータシステム

Absstract of: EP4711967A1

Systems and method for generating a patient specific CAD model of a mitral valve include receiving digital images of a mitral valve of a patient and segmenting the digital images to identify structures of the mitral valve. A CAD model of the mitral valve is generated including modeled structures representing the identified structures. The modeled structures in the CAD model are connected at multiple locations. First loading conditions for the modeled structures are determined using a first hemodynamics model. Movement of the modeled structures are simulated based on the first loading conditions. A specified area is determined based on the CAD model. Second loading conditions are determined using a second hemodynamics model that receives the specified area as an input. The CAD model is calibrated by modifying a configuration of the modeled structures in the CAD model based on the loading conditions and movement of the modeled structures.

NOISE CANCELLATION BASED ON COMMUNICATION BETWEEN EAR-WORN DEVICES

Absstract of: US20260089433A1

Two or more microphone arrays in an ear-worn device such as an earbud may detect a sound generated by a source body. A processor of the earbud may generate, based on the sound, a noise cancellation data package including an anti-phase sound. The processor may transmit the noise cancellation data package to a second earbud to cancel the sound for another body.

TECHNOLOGIES FOR INFERRING A PATIENT CONDITION USING MACHINE LEARNING

Absstract of: US20260088175A1

0000 A machine learning compute device may include circuitry configured to obtain sensor data from a product associated with a patient. The circuitry may also be configured to obtain response variable data indicative of an actual condition of the patient associated with the sensor data. Additionally, the circuitry may be configured to train, based on the response variable data and the sensor data, an inference model to infer the actual condition of the patient from the sensor data.

Method for Optimization of Orthopedic Component Design

Absstract of: US20260083510A1

Methods for understanding external and internal anatomy of bones through the use of imaging data and 3D modeling to facilitate the design of anatomically correct plates, devices and implants are disclosed. In one aspect the method results in an implant or plate that includes at least one curved surface wherein a contour of the at least one curved surface corresponds to an anatomic shape of a subject. The anatomic shape of the subject being determined based on an image of the bone.

ADDITIVE MANUFACTURING OF VINYL, PHOTOCROSSLINKABLE POLYMERS

Absstract of: US20260083877A1

0000 Various precursor solutions and methods of 3D printing and other additive manufacturing approaches are provided for the manufacture of articles using photocrosslinkable vinyl shape memory polymers. In various aspects, articles are manufactured by a process comprising (i) exposing a precursor solution to an intensity and frequency of light to initiate photo-polymerization of the precursor solution to form a layer of the article; and (ii) repeating step (i) a number of times to form the article in a layer-by-layer approach; wherein the precursor solution comprises a first polymeric precursor comprising a plurality of vinyl terminated side-chains attached thereto. A vinyl-functionalized, photocrosslinkable SMP used as an example herein is a novel variant of a previously disclosed SMP composition, with higher amounts of vinyl functionalization but similar thermomechanical properties to the SMP library previously disclosed. Moreover, a unique combination of chemistries is disclosed that incorporates the aforementioned vinyl-functionalized SMPs along with acrylate-based crosslinkers. Additional novel compositions are disclosed containing the vinyl-functionalized SMPs with additional dithiol functionalizations, vinyl-functionalized SMPs with dithiol crosslinkers, as well as vinyl-functionalized SMPs with both acrylate-based and dithiol crosslinkers, as another means to tune degradation rates and other material properties. The articles can include a variety of articles such a

DIABETES MANAGEMENT PARTNER INTERFACE FOR WIRELESS COMMUNICATION OF ANALYTE DATA

Absstract of: US20260089162A1

Systems, devices, and methods are disclosed for wireless communication of analyte data. In embodiments, a method of using a diabetes management partner interface to configure an analyte sensor system for wireless communication with a plurality of partner devices is provided. The method includes the analyte sensor system receiving authorization to provide one of the partner devices with access to a set of configuration parameters via the diabetes management partner interface. The set of configuration parameters is stored in a memory of the analyte sensor system. The method also includes, responsive to input received from the one partner device via the diabetes management partner interface, the analyte sensor system setting or causing a modification to the set of configuration parameters, according to a system requirement of the one partner device.

INFUSION SYSTEMS AND METHODS FOR PATIENT ACTIVITY ADJUSTMENTS

Absstract of: US20260088150A1

Techniques disclosed herein relate to operating a fluid delivery device in a personalized manner based at least in part on historical data of a patient. In some embodiments, the techniques involve obtaining historical meal data for the patient associated with historical meal events for the patient; determining a meal content based at least in part on the historical meal data; obtaining nutritional information associated with the meal content and historical meal events for the patient; determining, by a control system, a dosage of insulin based at least in part on the nutritional information and the historical meal events; and operating, by the control system, an actuation arrangement of the infusion device to deliver the dosage of the insulin to the patient.

FLOW METER AND RELATED METHOD

Absstract of: US20260088149A1

This disclosure relates to a gravity-driven infusion system that uses image-based monitoring to regulate flow. A contrasting, infrared-backlit wall and camera capture pendant drops and meniscus levels within a transparent drip chamber. The controller defines a baseline referenced to the spout or meniscus and fits sparse spline points on the drop perimeter to derive geometric functionals, such as neck width and centroid height. Temporal changes of these functionals map directly to instantaneous flow without explicit volume integration. An optional Young-Laplace model provides a physics-based boundary and confidence metric. A meniscus trend yields a low-frequency flow estimate. Confidence-weighted fusion controls a flow-control valve that compresses a multi-lumen insert. An independent safety occluder and watchdog ensure fail-safe shutdown. A medication library stores fluid-aware calibration. Multi-source embodiments orchestrate multiple controllers with virtual head-height equalization and verified handoffs. It performs pre-infusion checks, logs uncertainty, and supports tilt compensation too. Continuous stream detection triggers alarms.

PERSONALIZED AVATAR RESPONSIVE TO USER PHYSICAL STATE AND CONTEXT

Absstract of: US20260088164A1

Systems and methods are disclosed that facilitate providing guidance to a user during performance of a program or routine using a personalized avatar. In an aspect, a system includes a reception component configured to receive biochemical information about a physiological state or condition of a user, including information identifying a presence or a status of one or more biomarkers. The system further includes an analysis component configured to determine or infer one or more characteristics of the physiological state or condition of the user based on the information identifying the presence or the status of the one or more biomarkers, and a visualization component configured to adapt an appearance of an avatar presented to the user based on the one or more characteristics to reflect the one or more characteristics.

AUTOMATIC IDENTIFICATION OF REGIONS OF INTEREST IN INTRAORAL SCANNING SYSTEM

Absstract of: WO2026060653A1

An intraoral scanning system (100), a method (300), and a device (800) for automatic identification of region(s) of interest in a 3D representation of an oral cavity. The method (300) comprises obtaining, using an intraoral scanner, a point cloud representing a 3D geometric surface of an oral cavity (310); identifying, based on the point cloud, at least one region of interest on the 3D geometric surface of the oral cavity (320); and displaying the 3D geometric surface of the oral cavity with the at least one region of interest highlighted or marked (330).

Therapeutische Vorrichtung

Absstract of: DE102025002943A1

Als Hauptanspruch für die therapeutische Vorrichtung dient eine Einrichtung zur Erkennung, Auswertung und der dauerhaften Beseitigung körperlicher Fehlhaltungen im orthopädischen Sinn und betrifft hauptsächlich die Sitzhaltung, ist aber auch geeignet für andere alltägliche Situationen und gilt in selbem Maße auch für langanhaltende stehende Tätigkeiten- Die dafür eingesetzte therapeutische Einrichtung besteht im Sinne der Erfindung unter anderem aus im Alltag gebräuchlichen, handelsüblichen Oberbekleidungsstücken in alltäglicher Ausführung und Form, sowie für jedes Geschlecht und jedes Alter, die nachfolgend als Haltevorrichtung bezeichnet werden- Die Haltevorrichtungen 10 oder 11 werden für den täglichen Gebrauch vom(von der) Anwender(in) derart vorbereitet, in dem die kompakten Funktionseinheiten 41a bis 41d auf verschiedene Art und Weise in die Haltevorrichtung 10 oder 11 eingesetzt werden. Grundsätzlich wird dies rückennah im Winkel von 90° symmetrisch zur Senkrechten (Wirbelsäule) vorgenommen- Das geschieht zum einen dadurch, dass in die Haltevorrichtung 10 oder 11 jeweils eine maßgenau passende Tasche positionsgerecht befestigt wird, in die dann die Teilfunktionseinheiten 20a bis 21b lose eingesteckt werden. Tasche bedeutet in diesem Kontext, dass auf die Unterlage 30 eine Stoffabdeckung dergestalt aufgenäht wird, dass eine Tasche entsteht, die entweder nach oben oder seitlich offen ist. Außerdem bleibt ringsum ein schmaler Rand stehen, damit di

NERVE CONDUIT FROM DECELLULARIZED PLANT THAT CAN BE USED WITH OR WITHOUT ANY DRUG RELEASE POTENTIAL

Absstract of: WO2026063889A1

The present invention relates to a nerve conduit obtained by plant decellularization, which does not require 3D printing, is multi-channel, low-cost and capable of drug release. This nerve conduit is functionalized with GelMA and has properties that promote nerve healing.

PATIENT SPECIFIC APPLIANCES

Absstract of: US20260083531A1

0000 A dental device may include a body having first tooth receiving cavities shaped to receive teeth of a first side of an arch of a patient. The dental device may also include second tooth receiving cavities shaped to receive teeth of a second side of the arch of the patient and a palatal portion that extends between the first tooth receiving cavities and the second tooth receiving cavities. The palatal portion may be shaped to apply an expansion force to the teeth of the first side of the arch of the patient and the teeth of the second side of the arch of a patient. The palatal portion may also include a plurality of bands that extend between the first tooth receiving cavities and the second tooth receiving cavities. Each respective band may have a respective different thickness.

SYSTEMS FOR DETERMINING SIMILARITY OF SEQUENCES OF GLUCOSE VALUES

Absstract of: US20260083358A1

0000 In implementations of systems for determining a similarity of sequences of glucose values, a computing device implements a similarity system to receive input data describing a sequence of user glucose values measured by a continuous glucose monitoring (CGM) system. The similarity system computes similarity scores for a plurality of sequences of glucose values by comparing each glucose values included in the sequence of user glucose values with ever glucose value included in each sequence of the plurality of sequences. A particular sequence of glucose values that is associated with a highest similarity score is identified. The similarity system determines an externality associated with the particular sequence. The similarity system generates an indication of the externality for display in a user interface.

SYSTEMS AND METHODS FOR TREATING BLOOD CLOTS WITH NERVE STIMULATION

Absstract of: US20260088185A1

0000 Systems and methods are provided for treating blood clots associated with a replicating pathogen, such as a virus in the coronaviridae family. The systems and methods include applying an electrical impulse transcutaneously through the outer skin surface of the patient to a cervical branch of the vagus nerve of the patient. The electrical impulse is sufficient to reduce a number of antibodies associated with blood clotting to reduce a level of blood clotting in the patient. The systems and methods are particularly useful for treating post-COVID conditions or post-acute sequelae of COVID-19 that develop in “long-haul” or COVID patients.

GUIDE PLATE FOR THE ANATOMICAL REALIGNMENT OF BONE FRACTURES

Absstract of: US20260083487A1

Guide plate for the anatomical realignment of a plurality of fractured bone portions, comprising a back surface configured such as it can be distinctively coupled to the surface anatomy of the area of said plurality of fractured bone portions and characterized by a first plurality of holes placed on a first portion of the guide plate and a second plurality of holes placed on a second portion of the guide plate, wherein the first plurality of holes is misaligned with respect to the second plurality of holes.

COMPACT FIBER STRUCTURES FOR SNAPSHOT SPECTRAL AND VOLUMETRIC OCT IMAGING

Absstract of: US20260085975A1

The present disclosure relates to a custom waveguide array to encode 3-dimensional data for snapshot imaging techniques like imaging spectrometry or volumetric spectral domain OCT. The custom waveguide array has a series of waveguides such as optical fibers having input ends and output ends. The input ends are grouped in a dense array input area. An array output area creates void spaces for the output ends. The output area thus may used to provide spectral information for an object imaged by the input area. The fiber arrays may be manufactured with an entirely automatic development process based on 3-D printing techniques such as 2-Photon Polymerization (2PP) additive manufacturing.

GENERATION OF SYNTHETIC RADIOLOGICAL IMAGES

Absstract of: US20260087709A1

0000 The present invention relates to the technical field of radiology. The invention relates to a new approach for training a machine learning model for generating synthetic radiological images on the basis of measured radiological images and to the use of the trained machine learning model for generating synthetic radiological images.

AUGMENTED REALITY SYSTEMS, DEVICES AND METHODS

Absstract of: US20260086626A1

0000 One example of the present application discloses an augmented reality (AR) method and system which may connect a remote expert with a front line worker. A first video stream from a 2D camera at a first location where the remote expert is located is processed in real time to determine 3D coordinates of a hand of the remote expert. An AR model is mapped to the 3D coordinates of the hand of the remote expert and rendering in real time as a first AR image in a AR headset at a second location at which the front line worker is located. Further examples relate to an augmented lighting system and an augmented optics system.

INORGANIC STRUCTURE AND METHOD FOR MANUFACTURING INORGANIC STRUCTURE

Nº publicación: US20260085448A1 26/03/2026

Applicant:

OSAKA UNIV [JP]
OSAKA UNIVERSITY

Absstract of: US20260085448A1

An inorganic structure having mechanical properties that differ depending on the region in the inorganic structure, and a method for manufacturing the inorganic structure are provided. An inorganic structure (1) of the present embodiment includes a plurality of solidified portions (SA) composed of an inorganic material. The plurality of solidified portions (SA) include a first solidified portion (SA1) having a first crystallographic direction (CO1) preferentially oriented in a predetermined direction, and a second solidified portion (SA2) having a second crystallographic direction (CO2) that is a different orientation from the first crystallographic direction (CO1).