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487
results.
Updated on
13/11/2026 [07:35:00]
Results 250 to 275 of 487
Absstract of: CN122954740A
本发明公开了吲哚美辛控释片及其制备组合物和制备方法，属于现代药物制剂技术领域。该制备组合物包括低载药比混合物和高载药比混合物，所述低载药比混合物和高载药比混合物均包含吲哚美辛、填充剂、亲水凝胶骨架材料、增稠剂和黏合剂，所述低载药比混合物还包含润湿剂；所述低载药比混合物中吲哚美辛占该混合物中固体物料质量的1%~20%，所述高载药比混合物中吲哚美辛占该混合物中固体物料质量的50%~90%，该制备组合物通过一次成型的3D打印工艺，即可制得在预定时间段内恒速释药的控释片。
Absstract of: CN122956709A
本发明公开了一种3D打印辅助美学膜龈增宽手术的牙周导板的制备方法，所述方法包括：获取患者包括口扫数据、面扫数据、电子面弓数据；将获得的数据导入牙科CAD设计软件并整合，重建虚拟患者，生成获取牙列第一模型；根据所述牙列第一模型，确定上前牙的牙冠长度和上前牙龈缘位置，生成数字化美学虚拟修复体；纵向测量所述美学虚拟修复体的龈缘下移高度；将所述美学虚拟修复体与所述口扫数据合并生成第二模型；在所述牙科CAD设计软件中导入所述第二模型，确定绘制牙周导板范围，生成所述牙周导板的模型数据；基于所述牙周导板的模型数据进行3D打印，获得所述牙周导板。本发明还公开了上述方法制备获得的牙周导板，具有广泛应用价值。
Absstract of: CN122955106A
本发明公开了一种柔性光治疗面膜及其制造方法，包括有依次设置的上保护层、封装绝缘层、导电线路层、LED芯片层、封装胶层；其中，所述上保护层的材质为热塑性聚氨酯胶粘剂或硅胶、厚度为50‑200μm；所述封装绝缘层的材质为硅胶或光固化胶，厚度为10‑50μm；所述导电线路层的材质为银导电胶，线宽50‑200μm，厚度10‑50μm；所述LED芯片层的芯片尺寸为50‑500μm，排列密度10‑100个/cm²，相邻间距为1‑10mm；所述封装胶层的材质为聚酰亚胺胶粘剂或硅胶，所述聚酰亚胺胶粘剂的厚度小于15μm，所述硅胶的厚度小于50μm。采用聚酰亚胺（PI）旋涂工艺制备柔性基板，通过红外激光或紫外激光技术实现Micro/Mini LED芯片精准转移，并结合高精度3D导电胶打印技术制备超薄、柔性、高密度光治疗面膜。
Absstract of: CN122955026A
本发明涉及医疗器械技术领域，具体涉及一种心肌补片及其制备方法。心肌补片，其包括叠层设计的基底层和顶层；基底层以三维多孔水凝胶为基体，负载有间充质干细胞或者心肌细胞；顶层以水凝胶为基体，其表面设计有微沟槽阵列，微沟槽中接种心肌细胞。本发明提供的心肌补片通过设定三维多孔的基底层为组织再生提供临时力学支撑，整体的宏观压缩模量稳定在10~60 kPa，与天然心肌动态力学特性高度匹配，可适应心脏周期性搏动，避免应力失配引发的组织损伤与术后并发症。此外顶层微沟槽阵列诱导心肌细胞沿沟槽定向排列、同步收缩与功能成熟，实现高效细胞导向与组织整合，同时最大程度保留水凝胶生物活性与细胞相容性。
Absstract of: WO2025074338A1
Methods and systems for generating one or more health care alerts for one or more patients are disclosed. Real-time or near real-time measurement data is received from one or more sensors located in a living environment of a senior patient, and is used to generate a status report of the patient. At least one rule pertaining to the patient is identified from an individual rules engine using the measurement data, wherein the identified rule is applied to generate an alert indicator for the patient. At least one rule from a population rules engine pertaining to the patient is identified using the measurement data from the patient and other measurement data from a patient population, and generate a health assessment for the patient. A user interface is generated on a care provider device including at least one of the measurement data, status report, alert indicator, and health assessment of the patient.
Absstract of: US20260325773A1
The present disclosure provides for a control system for a flow therapy apparatus. The control system can control delivery of a fraction of delivered oxygen (FdO2) to a patient. The control system can maintain the FdO2 at a target level during a therapy session. The control system can automatically control an oxygen inlet valve in order to control the flow of oxygen to the patient.
Absstract of: AU2025254558A1
Systems and methods include a component of a bone implant that includes a patient specific bone contacting surface and, optionally, at least one protrusion adjacent to or extending from the patient specific bone contacting surface. The at least one protrusion is configured for engaging a bone preparation in the bone. To prepare the bone for receiving the component, one or more cutting tool templates may be used. The one or more cutting tool templates may be fabricated to have a patient specific bone contacting surface that engages the bone that is to receive the implant component. A cutting tool is engaged in one or more of one or more slots defined by the cutting tool template(s) to remove surface portions of the bone to create the bone preparation for engaging the protrusion. The patient specific bone contacting surface of the component engages the bone.
Absstract of: AU2025237721A1
A medicinal supply management system manages distribution of medicinal supply. The system may implement a pooling algorithm for pooling studies together, across different countries, with different protocol labeling parameters and/or blinding parameters. The system may allocate unique identifiers for the pooled studies. The system may implement digital display labels on the medicinal product for up-to-date presentation of relevant information to healthcare providers administering the medicinal product. The system may further implement controlled packaging for maintaining proper storage of the medicinal product, e.g., during transport to the treatment site. The controlled packaging may further include sensors for monitoring the internal environment of the controlled packaging, to maintain proper storage of the medicinal product.
Absstract of: US20260331294A1
0000 A method for treating a patient with respiratory illness is described according to one embodiment. The method includes the steps of receiving a set of screening spirometry test data measured by a spirometer, generating a first patient performance score based on the received set of screening spirometry test data, generating one of a first high alert when the first patient performance score crosses a first threshold and a first low alert when the first patient performance score fails to cross the first threshold, receiving a set of at-home physiological test data, generating a second patient performance score based on the received set of at-home physiological test data, generating one of a second high alert when the second patient performance score crosses a second threshold and a second low alert when the second patient performance score fails to cross the second threshold, receiving a set of at-home patient survey data entered by the patient, generating a third patient performance score based on the received set of at-home patient survey data, and generating one of a third high alert when the third patient performance score crosses a third threshold and a third low alert when the third patient performance score fails to cross the third threshold.
Absstract of: US20260331252A1
A computer-implemented method is disclosed. The method includes determining whether one or more messages have been received while a user performs a treatment plan. The one or more messages may pertain to at least one of a user and a usage of the electromechanical machine by the user. The electromechanical machine may be configured to be manipulated by the user while the user is performing a treatment plan. The method also includes, responsive to determining that the one or more messages have not been received, determining, using one or more machine learning models, one or more preventative actions to perform. The method also includes causing the one or more preventative actions to be performed.
Absstract of: US20260325073A1
A device for monitoring a patient includes a substrate, an adhesive layer coupled to a first side of the substrate, and a circuit board coupled to a second side of the substrate. The adhesive layer is configured to adhere to a patient. The device includes a first plurality of input interfaces coupled to the circuit board. The first plurality of input interfaces configured to identify a particular injury location. The device includes a second plurality of input interfaces coupled to the circuit board. The second plurality of input interfaces configured to identify a patient injury type. The device also includes a wireless transmitter coupled to the circuit board. The wireless transmitter is configured to transmit medical information associated with the patient to a mobile device. The medical information includes data indicating a setting of each of the first plurality of input interfaces and the second plurality of input interfaces
Absstract of: US20260325268A1
0000 A method and device for processing oral scanning data, and an apparatus are provided. The method includes: performing a scanning task on a plurality of scan regions in an oral cavity in a preset scanning sequence; obtaining target scanning data of the current scan region when a scanning completion event of the current scan region is monitored; performing a data processing task on the target scanning data when no data processing task is being performed; and performing the scanning task on the next scan region according to the scanning sequence, and determining the next scan region as a new current scan region.
Absstract of: US20260324986A1
Presented herein are related to systems and methods of determining likelihood of vascular conditions using acoustic measurements of veins in limbs of subjects. A pressure cuff may be secured about a region of a limb of a subject, and may apply pressure to the region to compress a vein in the limb. A plurality of sensors may be positioned on the region of the limb. Each sensor may acquire a respective acoustic signal in response to the pressure cuff releasing the pressure to the region. A computing system may receive the plurality of acoustic signals from the plurality of sensors. The computing system may generate, according to the plurality of acoustic signals, a plurality of metrics. The computing system may determine, according to the plurality of metrics, a likelihood of a vascular condition in the vein in the limb of the subject.
Absstract of: US20260325081A1
An example system includes a memory; and processing circuitry coupled to the memory and configured to: receive electrocardiogram (ECG) data of a patient, wherein the ECG data is generated by one or more sensing devices of the patient based on physiological signals of the patient sensed by the one or more sensing devices; obtain a plurality of heartbeat intervals from the ECG data; sample a plurality of points for each respective heartbeat interval of the plurality of intervals; determine a slow-moving average for each sample point parameter of respective heartbeat intervals during a. first period of time; determine a fast-moving average for each sample point parameter of respective heartbeat intervals during a second period of time, determine a difference between the slow-moving average and the fast-moving average for each sample point parameter; and determine a risk level of a health event for the patient based on the determined differences.
Absstract of: US20260325742A1
0000 A wearable infusion pump assembly. The wearable infusion pump assembly includes a reservoir for receiving an infusible fluid and a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set. The fluid delivery system includes a controller, a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the external infusion set, the pump assembly comprising a pump plunger, the pump plunger having distance of travel, the distance of travel having a starting position and an ending position, at least one optical sensor assembly for sensing the starting position and ending position of the pump plunger distance of travel and sending sensor output to the controller, and a first valve assembly configured to selectively isolate the pump assembly from the reservoir, wherein the controller receives the sensor output and determines the total displacement of the pump plunger.
Absstract of: AU2026242142A1
A tensioner tool for assessing joint laxity is disclosed. The tensioner tool comprises a pair of pivotally coupled arms, each arm comprising a proximal handle portion, a distal portion, and an insertion tip selectively coupled to the distal portion. The pair of arms pivot between a compressed configuration for insertion within the joint and an expanded configuration for distraction of the joint by applying a force to the handles, thus spreading the insertion tips. The tensioner tool also comprises a force sensor configured to measure the force applied to the handle portion and a positional sensor configured to measure a separation distance between the pair of arms. The tensioner tool also comprises a processor configured to calculate a distraction force at the insertion tips based on the measured force and to calculate a tip distance between the insertion tips based on the measured separation distance. ep e p
Absstract of: US20260325382A1
Modules for housing electronic and electromechanical medical equipment including a system to measure and record administration of one or more IV medications or fluids for IV administration.
Absstract of: US20260325305A1
0000 Systems and methods for designing patient-specific orthopedic implants. The systems and methods can include automated collection protocols for available third-party data to use to generate surgical plans or patient-specific orthopedic implant designs. The system can identify triggers for collecting third-party data. The system can determine a confidence score for the collected third-party data based on the type of data, the source of the data, and the similarity of the data to patient data. The system can select parameters in the third-party data to integrate into designing a patient-specific implant or patient treatment.
Absstract of: AU2025271814A1
A patient care system for monitoring injections and/or a patient's adherence to a prescribed treatment regimen comprises: an autoinjector for administering a medicament, such as a growth hormone, in particular to a patient, wherein the autoinjector is configured to receive a cartridge, in particular a dual chamber cartridge, with the medicament, wherein a dose of the medicament corresponds to a complete content of the medicament in the cartridge, wherein the cartridge comprises a code which is indicative of the dose, and wherein the autoinjector comprises a code reader for determining the code, wherein the autoinjector is further configured to administer at least approximately the complete content of the medicament in one administration, a computing device, in particular a mobile and/or a handheld computing device, wherein the autoinjector is configured to send the code which is indicative of the dose of the medicament to the computing device via a wireless or wired connection, in particular in response to or prior to the administering of the medicament, wherein the computing device is configured to store the code in conjunction with a time stamp that is either determined by the computing device or sent together with the code by the autoinjector, wherein the time stamp is indicative of the time and/or the date of the administering of the medicament and wherein the computing device is configured to store the code in conjunction with the time stamp on a storage device, which is
Absstract of: US20260325481A1
The present disclosure provides methods for individualized selection of, and monitoring of treatment using a neurodegenerative therapeutic agent such as Sigma-1 receptor agonist therapy for a subject, based on changes in gene expression pre- and post-treatment. The present disclosure also provides methods to evaluate current status or risk of a subject in developing neurodegenerative disorders. Also provided are kits for practicing the methods.
Absstract of: US20260325780A1
A patient interface including a seal-forming structure with a textile membrane that has at least one hole such that the flow of air at a therapeutic pressure is delivered to at least an entrance to the patient's nares and/or an entrance to the patient's mouth. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in a cavity of a plenum chamber throughout the patient's respiratory cycle, in use. The textile membrane includes a first portion that is held in a relaxed state and a second portion that is held in a taut state. The taut state of the second portion is configured to allow the seal-forming structure to include a three-dimensional shape that has multiple curvatures.
Absstract of: US20260326382A1
0000 A method for 3D printing a patient-specific bone implant having variable density, in various aspects, comprises: (1) providing a thermoplastic polymer composition comprising: (A) between about 20% and about 50% bioactive agent by weight; (B) between about 0.5% and about 10% chemical foaming agent by weight; and (C) balance structural polymer by weight; (2) receiving, by computing hardware, a scan of a bone, the scan comprising at least a 3D image of the bone and radiodensity data for the bone; and (3) causing, by the computing hardware, a 3D printer to form the patient-specific bone implant from the 3D image using the thermoplastic polymer by modifying a 3D printing temperature of the 3D printer during printing of the patient-specific bone implant such that each portion of the patient-specific bone implant is produced at a temperature that corresponds to a desired density defined by the radiodensity data for the bone.
Absstract of: AU2026242121A1
Recommendations based on continuous glucose monitoring (CGM) are described. Given the number of people that wear CGM systems and because CGM systems produce measurements continuously, a platform that provides a CGM system may have an enormous amount of data. This amount of data is practically, if not actually, impossible for humans to process. In implementations, a CGM platform includes a data analytics platform that obtains glucose measurements provided by a CGM system and also obtains additional data associated with a user. The data analytics platform processes these measurements and the additional data to predict a health indicator by using models. This prediction serves as a basis for generating a recommendation, such as a message recommending the user take action or adopt a behavior to mitigate a predicted negative health condition. ep e p
Absstract of: AU2026242184A1
A medical system useful in the determination of future disease progression in a subject. More specifically the present invention applies machine learning techniques to aid prediction of disease pathology and clinical outcomes in subjects presenting with symptoms of cognitive decline and to expedite clinical development of novel therapeutics. ep e p
Nº publicación: US20260325224A1 22/10/2026
Applicant:
MENTICE INC [US]
MENTICE INC.
Absstract of: US20260325224A1
0000 A method and computer programs for guiding an implantable device during a clinical intervention are disclosed. The method comprises a) generating a 3D vasculature model; b) defining a target deployment plan of the device inside the 3D vasculature model; c) obtaining a configuration parameter of the device; d) receiving a live image feed corresponding to a real-time deployment of the device within the 3D vasculature model; e) segmenting the deployed device in the live image feed, and obtaining a point-to-point longitudinal trajectory of the deployed device; f) extracting the same configuration parameter as in step c) from the deployed segmented device; g) determining the trajectory of the deployed segmented device on the generated 3D vasculature model; h) comparing the determined trajectory and configuration parameter of the deployed segmented device with the feasible trajectory and configuration parameter; and i) assessing closeness between the defined target deployment plan and the real-time deployment based on the comparison.
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