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302
results.
Updated on
24/04/2026 [07:12:00]
Results 275 to 300 of 302
Absstract of: WO2026064596A1
A computer-implemented method and system for assessing vascular disease is disclosed. The disclosure provides receiving angiography image data, including a plurality of image frames captured over a sampling time-period for a subject; identifying a representative image frame from the plurality of image frames; segmenting the plurality of image frames to isolate a vessel region; inferring a plurality of centerline node points associated with a centerline of the vessel; tracking movement of the plurality of centerline node points between successive centerline node points of the plurality of angiogram image frames; registering each segmented frame of the plurality of image frames to the representative image frame; and determining a flow rate of the vessel based in part on a change in length of the vessel represented in successive registered image frames. In embodiments, resultant measurements and results may be displayed upon one or more user interfaces.
Absstract of: US20260083984A1
A control circuit (which may comprise a graphics processing unit) accesses a plurality of radiation treatment planning objectives for a particular patient. The control circuit then optimizes a first candidate radiation treatment plan for the particular patient as a function of those objectives. The control circuit can then detect modification of at least one of those objectives to provide a corresponding one or more modified radiation treatment planning objective. The control circuit can then optimize a second candidate radiation treatment plan as a function of the at least one modified objective. The control circuit can then present, via a shared user display, at least a first dose volume histogram that corresponds to the first treatment plan and at least a second dose volume histogram that corresponds to the second treatment plan. The first and second dose volume histograms can be visually distinguished from one another by other than color.
Absstract of: US20260088146A1
A method includes receiving, by a user device, a prompt associated with treatment of a patient. The method includes determining a treatment context for the treatment of the patient based on access to a back-end treatment context support system. The method includes processing the prompt in view of the treatment context using one or more trained machine learning models to generate one or more actionable recommendations. The method includes outputting the one or more actionable recommendations via at least one of the user device or an additional device associated with the user device.
Absstract of: DE102024127337A1
Die Erfindung betrifft eine Diagnoseverfahrens-Software zur Bereitstellung von Daten zur Herstellung einer Kiefer-Gebiss-Schiene für eine Person, wobei ein Ist-Zahnraum-Zustand und/oder Zahnstellung (1) und eine Ist-Kieferfunktion (2) erfasst werden, wobei- eine Ist-Körperhaltung (3) erfasst wird, und- ein Ist-Fußflächendruck (4) erfasst wird, und- der Ist-Zahnraum-Zustand und/oder Zahnstellung (1) mit einem Soll-Zahnraum-Zustand und/oder Zahnstellung (11) abgeglichen wird, um eine erste Abweichung (a) zwischen dem Ist-Zahnraum-Zustand (1) und dem Soll-Zahnraum-Zustand (11) zu ermitteln,- die Ist-Kieferfunktion (2) mit einer Soll- Kieferfunktion (12) abgeglichen wird, um eine zweite Abweichung (b) zwischen der Ist-Kieferfunktion (2) und der Soll-Kieferfunktion (12) zu ermitteln,- die Ist-Körperhaltung (3) mit einer Soll-Körperhaltung (13) abgeglichen wird, um eine dritte Abweichung (c) zwischen der Ist-Körperhaltung (3) und der Soll-Körperhaltung (13) zu ermitteln,- der Ist-Fußflächendruck (4) mit einem Soll-Fußflächendruck (14) abgeglichen wird, um eine vierte Abweichung (d) zwischen dem Ist-Fußflächendruck (4) und dem Soll-Fußflächendruck (14) zu ermitteln, wobei- die erfassten Daten zur Herstellung der Kiefer-Gebiss-Schiene genutzt werden, geeignet um die Abweichungen (a, b, c, d) zu verringern.
Absstract of: WO2026064437A1
Disclosed herein are methods, systems, and kits relating to identifying a subject as having or being at an increased risk of having a disease. The methods may include processing a biological sample obtained from an oral cavity of the subject at an oral point of care location. The methods may include generating a report identifying the subject as having or being at an increased risk of having the disease. The report may be generated remotely.
Absstract of: US20260088151A1
0000 Systems and methods for determining a multi-field dose for radiation therapy are provided. 1) one or more medical images of a patient and 2) a fluence map for each of a plurality of fields for radiation therapy of the patient are received. Fluence-related information is determined for each of the plurality of fields based on the fluence maps. The fluence-related information for the plurality of fields are aggregated. A multi-field dose for the patient is determined based on the one or more medical images and the aggregated fluence-related information using a machine learning based dose prediction network. The multi-field dose is output.
Absstract of: GB2644212A
A method of manufacturing a dental implant device 200 comprising affixing a first 210 and second 220 implant member using laser welding, joining or soldering such that there’s no gap. The first implant member is at least partially formed of a ceramic material and the second implant member is at least partially formed of a metal. The implant member comprises melting at least part of the material of the first and second implant member at the same time using a two-wavelength laser. Wherein the first wavelength is selected to be adsorbed by the first material and the second wavelength is selected to be adsorbed by the second implant. An associated dental implant is also provided. Additional methods are also provided which may comprise the use of infra or near infra red lasers, depositing metal on the implant members, positioning biocompatible soldering material in the vicinity of the first and second implant member and forming, using a 3d printer, the first and second implant member using a first and second powder material respectively.
Absstract of: WO2024182473A1
Systems, methods, and computer program products are provided for automated diagnostic imaging procedures. An example system includes at least one processor configured to: communicate, with a fluid injection system including a fluid injector, an imaging system including an imager, a sensor system including at least one sensor, and a user device, procedure data associated with a patient and a patient procedure associated with the patient; determine, based on the procedure data, whether a threshold for performing a next portion of the patient procedure is satisfied; and enable, based on a determination that the threshold for performing the next portion of the patient procedure is satisfied, at least one of the fluid injection system including the fluid injector, the imaging system including the imager, the sensor system including the at least one sensor, and the user device, to perform the next portion of the patient procedure.
Absstract of: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Absstract of: GB2700860A
A bioprinting apparatus 100 for 3D printing a model comprises a printing nozzle 115 for dispensing a magnetic or magnetisable bioink for forming the model; a bath 130 containing a model-supporting fluid; a mechanism 110 for moving the nozzle relative to the bath; and at least one magnet 140/145, i.e. a single magnet, a magnet array, magnetisable material or an electromagnet, at or adjacent to the bath 130 suitable for providing a magnetic field 10 in the bath of sufficient strength to influence bioink in the bath and hold bioink in the bath, for example in a stationary manner, until crosslinking occurs. The magnet element may be a magnet array arranged as a Halbach array. Preferably, the magnetic field may hold the bioink at a desired height at which embedded printing is to take place and a controller is operable to control the magnet to move to a different height corresponding to a different layer. The printed material may contain cells, such as eukaryotic cells, and the fluid may contain nutriments for the cells. Printing error correction is described also. Figure 1
Absstract of: AU2024288436A1
The invention relates to recombinant RE15mR and EJ17zipR hybrid proteins with the structure specified in the description, recombinant DNA sequences encoding recombinant hybrid proteins, vectors containing recombinant DNA sequences, as well as eukaryotic or prokaryotic expression systems transformed with recombinant DNA sequences. The invention also concerns the use of recombinant hybrid proteins as components of bioink intended for bioprinting, and also as components of biomaterials. Furthermore, the invention relates to the use of recombinant DNA sequences, vectors and eukaryotic or prokaryotic expression systems for the production of recombinant hybrid proteins.
Absstract of: EP4714365A1
Systems and methods for left atrial appendage closure device specification from two dimensional (2D) Intracardiac Echo imaging (ICE). In an imaging procedure, 2D ICE is used to acquire images of the left atrium (20) of a patient. A model (320) of the left atrium (20) is generated from the images of the left atrium (20). The model (320) of the left atrium (20) is used to validate subsequent imaging of the left atrial appendage (26) of the patient. Anatomical measurements from the validated subsequent imaging may be used to select or specify a left atrial appendage closure device in order to, for example, treat atrial fibrillation patients.
Absstract of: EP4714345A1
A method of dynamically determining a readiness score of a user using a wearable device. The method includes detecting, by the wearable device when worn by the user, one or more sensor or physiological signals associated with the user, and determining, by a processor, an estimation of two or more readiness components based on the one or more sensor or physiological signals. The two or more readiness components include a physical energy of the user associated with physical energy consumption of the user, physical energy recovery of the user, or both. The two or more readiness components also include a mental energy of the user associated with mental energy consumption of the user, mental energy recovery of the user, or both. The method further includes determining the readiness score based on the estimation of each of the two or more readiness components.
Absstract of: EP4714369A2
A surgical instrument including a flex circuit comprising a sensor system.
Absstract of: US2022184276A1
The present disclosure is directed to a degradable 3D-printable scaffold for use in tissue engineering, which scaffold has a combined gradient and staggered structure. Further provided is a medical device for use in tissue engineering, comprising such a scaffold. The present disclosure also provides a method for preparing a scaffold by additive manufacturing, e.g. 3D-printing, a method for in vivo tissue engineering, use of the scaffold in an in vitro cell culture system, in an in vitro method for culturing of cells and/or in an in vitro method for regenerating tissue. Also provided is a scaffold and a medical device for use in a method for in vivo tissue engineering. Further disclosed is a novel degradable copolymer of ε-caprolactone and p-dioxanone, which can be printed without degradation and which is particularly suitable for use as scaffold material in the scaffold and method according to the present disclosure.
Absstract of: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
Absstract of: EP4715752A2
Disclosed is a computer-implemented method of generating a dental model based on an objective function output, comprising creating an objective function comprising at least one quality estimation function which trains at least one machine learning method that generates quality estimation output, and an objective function output is the output of the objective function providing a model as an input data to the objective function and generating model-related objective function output; and modifying the model based on the model-related objective function output to transform the model to a generated model, wherein the generated model is the dental model.
Absstract of: EP4714352A2
0001 A system that executes a process for mapping cardiac fibrillation and optimizing ablation treatments. The process, in some embodiments, includes: positioning a two dimensional electrode array to several locations in a patient's heart and at each location, obtaining a conduction velocity and a cycle length measurement from at least two local signals in response to electrical activity in the cardiac tissue. In some embodiments, a regional wavelength is calculated by multiplying the local conduction velocity with the local minimum cycle length. The system can then create a wavelength distribution map that identifies the location of the drivers in the heart. In certain embodiments, the system uses variability of conduction velocity and cycle length in an area to determine the driver type. In some embodiments, the system calculates average distance of drivers to non-conductive tissue boundaries. The system then selects ablation placements that maximize treatment efficacy while minimizing tissue damage.
Absstract of: CN121398761A
Fixation devices for implants and related methods are generally described. The fixation device may be wrapped around the implant prior to delivery to reduce the risk of implant migration after implantation. The device may have porosity to induce tissue ingrowth around the implant and improve surgical outcome. The device can be used for rapidly preparing implants and can adapt to implants of various sizes. In some embodiments, the device may include a central portion for covering an anterior surface of a breast implant and a peripheral portion for covering a posterior surface of the implant. The peripheral portion, which may include a continuous rim or a plurality of legs, may include a tab that secures the fixation device to an implantation site. In some embodiments, a tether may be coupled to a distal end portion of the peripheral portion, thereby serving as a pull cord that quickly wraps the device around the implant.
Absstract of: AU2024276549A1
Methods of manufacturing a porous device for diffusing a fragrance using additive manufacturing including iteratively spreading a loose powder and selecting at least one process parameter to create a porosity within the porous device adapted to carry the fragrance from a fragrance reservoir to an exterior surface of the porous device. An additively manufactured device for diffusing a fragrance includes a diffuser having a plurality of pores defining a porosity of the diffuser, the porosity defining at least one of a rate of absorption, an amount of storage, and a rate of diffusion of the fragrance. A method of using a porous device includes filling the plurality of pores with fragrance and diffusing the fragrance from an exterior surface.
Absstract of: CN121240894A
The present disclosure relates to a hydrogel ink comprising a lipid particle, a polynucleotide supported within the lipid particle, and a bio-ink. In one embodiment, the lipid particles comprise extracellular vesicles. The disclosure also relates to hydrogels thereof and their use in treating neurological diseases or conditions or regenerating soft tissue.
Absstract of: CN121127203A
A computer-implemented method for predicting tooth positions, comprising: a) defining a plurality of tooth positions corresponding to a plurality of teeth in a dental arch; b) defining a plurality of appliance positions of the orthodontic appliance; c) determining one or more tooth position differences for each tooth; d) determining one or more appliance position differences for each tooth; e) determining one or more appliance-tooth relative differences for each tooth; f) modifying each tooth position of the plurality of tooth positions based on the corresponding one or more appliance-tooth relative differences; g) iteratively repeating steps c) to f) until a maximum change in each of the plurality of tooth positions is less than a convergence threshold; and h) defining the plurality of tooth positions obtained in the final iteration of step g) as a plurality of predicted tooth positions.
Absstract of: GB2700936A
A controller (300, figure 4) for a 3D bioprinter 10, the controller being operable to control the functioning of the 3D bioprinter housed within an internal area of an enclosure 100, to produce a 3D printed construct in accordance with a 3D printing file, said controller being further operable to control the temperature of at least two temperature regulating devices 112, 242, by means of control inputs from plural temperature sensors TP1,TP2,TP3, at least one sensor sensing the temperature of the print bed 240, of a print material store 210, and/or at least one temperature sensor of the bioprinter head 220, and wherein said temperature regulation includes causing: heating of one or more of said at least two devices, cooling of one or more of said devices, or heating of one of the devices at the same time as cooling of another of the devices. The temperature control may be a proportional-integral-derivative (PID) routine or circuit. A 3D printing assembly is also provided, suitable for bioprinting, including an enclosure defining an internal area 101 and one or more bioink material vial(s) 212 selectively fluidically interconnectable to the print head. Figure 2
Absstract of: JP2023050476A
To execute efficient tablet printing.SOLUTION: A tablet printing device 1 includes: a conveyance part 21 for conveying tablets T by a conveyance belt 21a; a detection part 22 for detecting the conveyed tablets T; an inkjet head 24 for discharging ink to the tablets T detected by the detection part 22; a moving mechanism 26 for moving the conveyance belt 21a or the inkjet head 24 so as to change an interval between a surface on a conveyance belt 21a side of the inkjet head 24 and a surface on an inkjet head 24 side of the conveyance belt 21a; and a control part (e.g., a control device 40) for controlling the conveyance part 21 and the moving mechanism 26. The detection part 22 detects height information on the tablets T on the conveyance belt 21a. The control part controls the conveyance part 21 so as to decrease a conveyance speed of the conveyance belt 21a when the height of the tablets T exceeds a predetermined threshold on the basis of the height information, and controls the moving mechanism 26 so as to widen the interval.SELECTED DRAWING: Figure 1
Nº publicación: JP2026509813A 25/03/2026
Applicant:
ジャイラスエーシーエムアイインクディー／ビー／エーオリンパスサージカルテクノロジーズアメリカ
Absstract of: EP1000000A1
The invention relates to an apparatus (1) for manufacturing green bricks from clay for the brick manufacturing industry, comprising a circulating conveyor (3) carrying mould containers combined to mould container parts (4), a reservoir (5) for clay arranged above the mould containers, means for carrying clay out of the reservoir (5) into the mould containers, means (9) for pressing and trimming clay in the mould containers, means (11) for supplying and placing take-off plates for the green bricks (13) and means for discharging green bricks released from the mould containers, characterized in that the apparatus further comprises means (22) for moving the mould container parts (4) filled with green bricks such that a protruding edge is formed on at least one side of the green bricks.
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