Absstract of: EP4832013A2
0001 A medical device is configured to receive a cardiac signal and determine a morphology matching score from the cardiac signal and a capture detection morphology template that corresponds to a first type of cardiac pacing capture that includes capture of at least a first portion of the His-Purkinje system. The device is configured to detect a second type of cardiac pacing capture in response to the morphology matching score being less than the first match threshold. The second type of cardiac pacing capture is different than the first type of cardiac pacing capture and may include capture of the ventricular myocardium and/or a second portion of the His-Purkinje system different than the first portion.
Absstract of: KR20260155905A
본 발명은 기계적 강도와 UV 저항성이 향상된 PMMA를 포함하는 DLP(Digital Light Processing) 인쇄용 조성물 및 이를 이용하여 제조된 마이크로니들 패치에 관한 것이다.
Absstract of: EP4830656A1
0001 Provided is an intelligent puncture navigation system and method. The system comprises a medical imaging device (1), an upper computer (2), a positioning device (3), and an intelligent puncture needle (4). The medical imaging device (1) is configured to acquire a three-dimensional scanning image of tissues to be punctured; the upper computer (2) is configured to determine puncture information according to the three-dimensional scanning image; the positioning device (3) is configured to form a mark on the skin surface of the area to be punctured according to the puncture information; the intelligent puncture needle (4) is configured to perform puncturing according to the mark and the puncture information and acquire real-time angle information of the puncture needle; the upper computer (2) is further configured to monitor the intelligent puncture needle (4) according to the real-time angle information. The intelligent puncture navigation system and method can achieve the navigation function without image registration, thereby avoiding puncture deviation or failure caused by image registration errors. The system and method offer flexible use and improve the puncture efficiency and accuracy.
Absstract of: EP4830666A2
0001 Certain aspects of the present disclosure provide a flexible scaffold implant comprising a plurality of layered structures, the plurality of layered structures comprising: a first layered structure having a three-dimensional (3D) shape and formed from a bioresorbable material, and a second layered structure conforming to the corresponding 3D shape of the first layered structure and formed from the bioresorbable material. The first layered structure is arranged in proximity to the second layered structure. The first layered structure is configured to dissolve for resorption at a different rate than the second layered structure based on design elements of the first layered structure and the second layered structure. The plurality of layered structures are flexible.
Absstract of: WO2025137128A1
The present disclosure provides polymerizable composition that can produce desirable stain resistant polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing polymerizable compositions, resins, devices, and polymeric materials. Also provided herein are methods of using polymerizable compositions, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.
Absstract of: EP4832004A2
0001 A system for use in a healthcare facility having a patient room. The system comprises a patient bed having bed circuitry including a first wireless transceiver and an AC power cord, and a wall module including a housing configured to be mounted at a fixed location in the patient room of the healthcare facility. The housing carries an AC receptacle and has a front wall that is formed to include a first recess in which the AC receptacle is accessible. The wall module further includes module circuitry carried by the housing. The module circuitry includes a second wireless transceiver and an AC plug sensor that forms an optical beam in the recess in front of the AC receptacle. In response to the optical beam being interrupted by a plug of the AC power cord being plugged into the AC receptacle, the second wireless transceiver communicates with the first wireless transceiver to implement a time-based wireless pairing operation between the wall module and the patient bed.
Absstract of: WO2025117862A1
Provided herein are various embodiments related to the design, creation, and use of a folded sheet scaffold for medical devices. The scaffold comprises a shellular porous pseudorandom orientable architecture composed of a continuous folded sheet of topological genus-n. Methods for designing the scaffold involve driving noise from an infinite 3D noise field to define a field with real space, tuning field values based on user input, and subtracting to create thin wall geometry. The methods can be computer-implemented or executed by a processor following instructions stored on a non-transitory computer-readable medium. A computer system for designing the scaffold includes modules for noise-driving, tuning, and subtracting. The disclosure also includes a folded sheet scaffold formed by these methods and a medical device comprising the folded sheet scaffold.
Absstract of: WO2022061007A1
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. In some cases, the device further comprises a third polymer layer. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
Absstract of: US2020222151A1
A system for dental implant restoration is provided. It includes universal aligning adaptors and prosthetic components having co-operable indices, which together form a translational, integrating system which aligns, synchronizes, and references the prosthetic components about an implant's central axis of rotation. Rotation of an adaptor about a prosthetic component, with its reference point becoming aligned to a predetermined reference point on the prosthetic component, followed by the rotation of the adaptor/prosthetic component assembly about the implant, situates the prosthetic component in a predetermined position such that all other prosthetic components become synchronized to the adaptor's reference point. The prosthetic component is mechanical for clinical or lab bench use, or is virtual for restoration design in a software program, prior to milling prosthetic abutments or devices. Abutments, healing caps and screw access holes are realigned to preferred positions and synchronized with minimal deviation from the ideal direction.
Absstract of: WO2025131708A1
The invention relates to a radically polymerisable compound represented by a structure of formula 1: PG1-Sp1-OC(O)NH-K-NHC(O)O-Arn-OC(O)NH-K-NHC(O)O-Sp2-PG2 ( formula 1), and to a radically polymerisable composition, to the use of the radically polymerisable compound or the radically polymerisable composition for producing a polymerisable dental material and to a cured dental material.
Absstract of: EP4830728A2
A method of treating psoriatic arthritis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves significant ACR20/50/70, PASI70/90/100, MDA, HAQ-DI, SF-36 PCS, MCS, LEI/dactylitis, PASDAS, GRACE, mCPDAI, DAPSA or RAPID3 improvement as measured 16, 24, 32, 40 and 48 weeks after initial treatment.
Absstract of: GB2705798A
A method 100 for reconstruction of 3D image of a patient is disclosed. The method comprises obtaining a projection set comprising a plurality of 2D CBCT projections of a first volume of the patient 110, and obtaining a 3D image of a second volume of the patient, wherein the second volume of the patient at least partially overlaps with the first volume of the patient 120. The method further comprises using acquisition information relating to the obtained projection set to generate, from the 3D image, synthetic projections of the second volume of the patient 130, and extending the projections of the first volume of the patient from the obtained projection set with information from the synthetic projections of the second volume of the patient 140. The method further comprises using the extended projections to generate a 3D image of a third volume of the patient, the third volume comprising a combination of the first and second volumes. (Figure 1)
Absstract of: GB2705670A
Apparatus 100 suitable for supplying a 3D printer 10, particularly a bioprinter, with a print material, for example bioinks, having a predefined ratio of components, the apparatus comprising plural component reservoirs 130A-C, for example vials, each reservoir holding a material to be printed and being in common fluid communication with a printing nozzle 114, one or more devices 124A-C for generating a pressure in each of the reservoirs for a selectable time period for dispensing a volume of the respective component out of the respective reservoir to the nozzle supply, and thereby to define a ratio of components. A controller 150 for controlling the or each device may be provided, UV light may be applied to the material and the ratio selected influences the intensity of UV the light applied. A method for mixing components of a 3D printable material to a predefined ratio is also provided. Figure 1.
Absstract of: EP4830663A1
Die Erfindung betrifft einen Abformlöffel zur Anfertigung von Gebissabdrücken mithilfe von Abformmaterial, ein Verfahren zur Herstellung sowie ein nichtflüchtiges Speichermedium , wobei der Abformlöffel umfasst: einen Löffelabschnitt, ausgestaltet zur Aufnahme des Abformmaterials, und einen Halteabschnitt, umfassend einen Haltegriff, wobei der Löffelabschnitt ferner zur Aufnahme eines Gebisses eines Ober- oder Unterkiefers ausgestaltet ist, dadurch gekennzeichnet, dass eine Oberfläche des Abformlöffels zumindest in Teilen des Löffelabschnitts eine Gitterstruktur aufweist, die zur Aufnahme des Abformmaterials ausgestaltet ist.
Absstract of: US20250108658A1
0000 Provided are temporary tattoos comprising cosmetic inkjet ink and methods of making thereof. The method of making the temporary tattoo may comprise printing, using an inkjet printer, an image made from a cosmetic inkjet ink on a side of a transfer film that comprises an inkjet receptive coating. The image printed on the transfer film may be dried to allow the image to absorb into the coating. Once dried, an adhesive may be applied to the side of the transfer film comprising the inkjet receptive coating to cover the image. Thus, the temporary tattoo may comprise a transfer film comprising an inkjet receptive coating, and an adhesive film.
Absstract of: MX2026002915A
Methods, systems, and apparatuses are described herein for using processes and machine learning techniques to optimize medical imaging processes to reduce inadvertent exposure to harmful radiation. A machine learning model may be trained to output recommended medical imaging device operating parameter settings. Available operating parameters of a medical imaging device may be determined, and patient data may be received. The patient data and the available operating parameters may be used as input to the trained machine learning model, which might output recommended operating parameter settings. In turn, this output in addition to other calculations might be used to transmit, to the medical imaging device, data that causes modification of the operating parameters of the medical imaging device. Metadata corresponding to one or more images captured by the medical imaging device may be received, and the trained machine learning model might be further trained based on that metadata.
Absstract of: CN122973017A
本发明涉及医疗器械与人工智能交叉技术领域,具体的说是一种面向全科门诊的乏力症状多模态客观评估装置及方法,本发明通过多模态生理信号采集模块同步采集患者眼睑结膜图像、表面肌电信号、心率变异性信号及语音信号,经自适应预处理后提取多维特征参数,输入带有动态权重调整机制的多模态融合模型,综合生成乏力风险分层结果及病因偏向性提示,最终输出结构化评估报告并提供临床决策辅助。本发明解决了现有技术中乏力评估完全依赖主观量表、准确性差、标准化程度低的问题,实现了乏力症状的无创、快速、客观量化评估,可有效辅助全科医生进行鉴别诊断,提高诊疗效率和准确性,适合在各级医疗机构全科门诊广泛推广应用。
Absstract of: CN122973014A
0001 本发明涉及一种可穿戴式柔性凝血监测传感器,该可穿戴式柔性凝血监测传感器通过柔性传感基底、集成检测电路、显示单元、人机交互单元和无线通信单元,柔性传感基底为具备力致变色能力的生物相容性柔性弹性体基底,用于承载各功能单元并反馈传感器的形变状态与贴合度;集成检测电路整体制备于柔性传感基底上,通过量子隧穿检测单元采集血液阻抗/容抗变化信号,经信号调理、模数转换后传输至微控制器,提取凝血监测核心指标,同步实现数据显示、人机交互与无线传输,其优点在于具备生物相容性高、柔韧性好、高度集成且具备自指示功能的柔性传感器产品,适于长期穿戴或短期植入,用于体内凝血监测的技术效果。
Absstract of: CN122991484A
本申请一种服务器、医学成像扫描系统及其扫描控制方法,服务器包括:交互单元,用于接收用户的自然语言输入,自然语言输入表征用户对于当前扫描协议的调整需求;智能体单元,用于根据用户的自然语言输入确定目标任务,并将目标任务规划为多个目标子任务,多个目标子任务的顺序组合形成决策树;根据决策树,按顺序执行目标子任务,且响应于至少一个目标子任务对应的中间结果未满足设定阈值,调整决策树或重新进行目标任务的规划,以生成当前扫描协议的推荐扫描参数。此外本申请还提供了医学成像扫描系统及医学成像扫描系统的扫描控制方法。本申请的实施例可以实现用户采用文本描述对扫描协议进行检索,提高检查效率。
Absstract of: CN122973153A
描述了一种针对用于增材制造牙齿修复体的材料的材料存储容器。所述材料存储容器包括接收空间和供应口,所述供应口以材料输送方式耦合到所述接收空间,以至于材料可以通过所述供应口从所述接收空间供应以用于增材制造所述牙科修复体。至少在至少一项材料特性上不同的第一材料和第二材料被布置在所述接收空间中。所述第一材料和所述第二材料沿所述接收空间的排放方向接连地布置。或所述第一材料和所述第二材料沿垂直于排放方向的方向接连地布置。还阐述了一种用于填充材料存储容器的方法。还解释了一种用于增材制造牙齿修复体的装置和一种用于增材制造牙齿修复体的方法。
Absstract of: CN122976030A
本发明涉及医用敷料3D打印控制技术领域,涉及基于多组分药料配给的医用敷料3D打印控制方法及系统。其包括:获取目标敷设区域轮廓数据及多种药料组分的配给参数;生成打印区域并划分打印单元,构建对应路径段的打印路径;确定各打印单元中不同药料组分的单位面积目标药料量,并结合路径段有效打印宽度及打印头运动速度确定供料参数;根据边缘承载状态和易迁移药料配给状态确定边缘药料逸散风险系数及配给修正量,在边缘修正打印单元与内部相邻打印单元之间重新分配易迁移药料组分,更新单位面积目标药料量并修正供料参数,控制打印头及药料供给通道完成打印。本发明可降低不规则敷料打印中的单位面积药料沉积偏差及边缘易迁移药料脱落风险。
Absstract of: CN122979704A
本发明属于医用植入金属材料技术领域,具体涉及一种Ti13Nb14Zr1Cu医用钛合金及其制备方法和应用,本发明所述合金为β型医用钛合金,以质量百分含量计包含Nb 13%、Zr 14%、Cu 1%,余量为Ti;Nb、Zr用于稳定β相结构并保障生物相容性,Cu以合金化形式均匀分布,赋予材料抗菌性能,并协同提升成骨与促血管生成能力。本发明采用电子束熔融增材制造工艺制备,可构建单元尺寸1.5mm、孔隙率50%~80%的三周期极小曲面G结构三维连通多孔结构,实现成分调控与多孔结构一体化成形。该合金同时兼具成骨促进、抗菌及促血管生成性能,效果优于纯钛,适用于骨缺损修复、牙科植入等医用植入领域。
Absstract of: CN122973706A
本发明涉及生物材料与组织工程领域,涉及一种负载miR‑210@ZIF‑8的应力松弛水凝胶心脏补片,包括复合水凝胶基质,复合水凝胶基质为双交联网络结构,双交联网络结构包括可光交联高分子形成的光交联稳定网络,以及含醛基多糖与含氨基蛋白质通过动态席夫碱键构筑的动态交联网络;动态交联网络具备应力松弛与应力耗散特性,光交联稳定网络维持心脏补片的结构与尺寸稳定性;miR‑210@ZIF‑8纳米颗粒均匀分布于复合水凝胶基质内部,且miR‑210@ZIF‑8纳米颗粒具有酸性响应释药特性。本发明具有能够协同调控心肌梗死后异常力学微环境与缺氧代谢障碍,有效抑制线粒体过度分裂,显著提升心肌修复效果和抗纤维化能力。
Absstract of: CN122973691A
本发明属于骨修复生物材料领域,涉及一种用于大段骨缺损修复的空间流体导向型多通道生物陶瓷支架及其制备方法与应用。所述支架由多层交错堆叠的支撑单元阵列构成,每个支撑单元阵列由多个支撑单元组成且至少部分支撑单元的内部沿其轴向长度方向设置有多个贯通导流通道;所述贯通导流通道通过层间孔隙相互连通,形成由支架边缘区域延伸至中心区域并贯穿支架轴向长度的连续空间流体导向网络。实验结果表明,所述支架在大段骨缺损修复中能够促进缺损区域均匀血管化骨再生。
Nº publicación: CN122973179A 27/10/2026
Applicant:
苏州爱杰硕医疗科技有限公司
Absstract of: CN122973179A
本发明公开了一种基于热压渗透和锚定的PEEK‑钛合金复合植入物及制备方法。该方法包括构建PEEK基体与钛合金多孔结构模型,在多孔结构朝向PEEK侧设计T型凸台、倒锥形柱或仿生树根状等锚定结构;采用3D打印技术一体成型带锚定结构的TC4多孔构件;采用FDM或注塑成型PEEK基体并预留容纳腔;通过热压处理使PEEK熔体渗入多孔结构及锚定结构间隙,冷却后形成机械互锁与渗透固定的双重结合。本发明解决PEEK与钛合金异质材料界面结合强度不足难题,制得复合植入物兼具PEEK与骨匹配的弹性模量和钛多孔结构的优异骨整合能力,界面拉伸剪切强度可达25‑45MPa,适用于股骨髁、脊柱融合器等多种骨植入物。