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适用于脑卒中患者的手功能康复评估系统及其训练方法

Absstract of: CN122604402A

本发明属于医疗康复相关技术领域，其公开了一种适用于脑卒中患者的手功能康复评估系统及其训练方法，系统包括：数据接收模块，用于接收患者执行上肢运动功能评估设定动作时的上肢多模态时序数据；特征融合模块，用于对数据进行特征提取后再融合，得到时空融合特征矩阵；肌肉协同量化模块，用于基于手臂肌电数据提取协同模式相似度、肌肉协同耦合度、激活时序同步性；运动协同量化模块，用于基于运动学数据提取运动协同耦合度；输入特征构建模块，用于将、、、与时空融合特征矩阵进行拼接得到输入特征矩阵；神经网络预测模块，用于根据输入特征矩阵实现患者手功能康复程度的预测。基于以上系统，可以实现脑卒中患者手功能康复的自动化评估。

一种多模态神经生理信号处理方法、系统及可读存储介质

Absstract of: CN122604394A

0001 本申请公开了一种多模态神经生理信号处理方法、系统及可读存储介质。该方法包括：在静息态及诱发任务态下被动采集受试者的多模态生理信号；在诱发任务态中获取受试者的配合度特征与信号质量特征，并利用语言模型动态调整诱发任务内容与呈现节奏；基于对应年龄段的模板头骨模型对脑电信号进行源定位逆向求解提取源空间特征；计算源空间特征相对于发育常模数据的偏离量特征并融合生成多模态发育偏离特征向量；将多模态发育偏离特征向量输入偏离评估模型进行处理，输出状态偏离评分数据以及数据分析报告。本申请能够降低随年龄物理变化带来的源定位误差，剥离发育波动干扰并提高信号质量。

超声智能质控诊断管理系统

Absstract of: CN122619338A

本发明涉及超声智能协同质控技术领域，尤其涉及超声智能质控诊断管理系统，包括：数据获取模块，从超声设备和病案中获取影像及文本数据并提取关键信息；切面识别模块，结合关键信息通过深度学习识别切面类型；特征提取模块，利用语义分割获得质控特征；质控评分模块，比对预设规则生成质量评分；协同会诊模块，评分低于阈值时触发会诊并重新采集，合格则触发自动测量；自动测量模块，获得测量指标值；报告录入模块，比对知识库参考值并自动录入结构化报告；综合管理模块，循环执行所有预设切面，生成完整质控报告，并加密存储及多因素认证控制访问。本发明实现超声检查全流程自动质控与协同管理，提升诊断规范性与效率。

一种用于评估腓肠肌反弹力特性的肌肉功能的检测方法

Absstract of: CN122604400A

本发明涉及肌肉生物力学评估技术领域，具体为一种用于评估腓肠肌反弹力特性的肌肉功能的检测方法，包括：通过分解采集的生理与物理信号，分离出主动与被动分量并融合为复合特征向量。依据腓肠肌解剖结构，将其体表投影区域虚拟划分为具有层次结构的特征分析区块并赋予权重，据此计算整体动态响应指数。结合腓肠肌生物力学仿真模型，逆向求解出内部不同深度肌纤维束的即时张力分布，进而推算弹性势能储存与释放效率，通过与预设阈值比较确定反弹力特性等级。该方法实现了基于解剖结构的分区精准评估，并通过模型逆向求解获得了肌纤维束级的深层力学状态，提升了评估的解剖学精确性与力学深度。

Méthode de fabrication d’hydrogel et ses utilisations

Absstract of: FR3172321A1

L’invention concerne un procédé de fabrication d’un hydrogel à partir d’au moins un polymère réticulable, le procédé comprenant les étapes suivantes : a) fournir une solution comprenant au moins un polymère réticulable et une oxydase, b) réticuler ledit au moins un polymère par l’oxydase et à l’aide d’H2O2 afin d’obtenir un hydrogel, où la source d’H2O2 lors de l’étape b) est fournie par un dispositif de génération d’un plasma froid. Figure pour l’abrégé : Figure 1

自动评定牲畜动物的血液中的维生素状态的方法、系统

Absstract of: WO2025176897A1

The method (100) to automatically assess a vitamin status in the blood of a livestock animal comprises the steps of: locally, collecting (105) a drop of blood from a livestock animal on a carrier, locally, drying (110) the drop of blood of the livestock animal on the carrier, sending (115) the carrier to a remote location, via a transport vessel, said remote location comprising at least one metabolized vitamin assessment device, calculating (120), by a computing device connected to the assessment device in the remote location, a vitamin status value in the blood of the livestock animal on the carrier, determining (125), by a computing device, as a function of the calculated vitamin status value and of a target vitamin metabolite value, a livestock animal vitamin status, and locally, providing (130) the livestock animal vitamin status.

用于基于用户的生理参数控制神经调控设备的操作的人工智能(AI)系统和方法

Absstract of: US20250205487A1

An artificial intelligence (AI)-based system and method for controlling operations of neuromodulation devices based on physiological parameters of users is disclosed. The AI-based system comprises one or more physiological parameters sensing endpoint devices and one or more server devices. The one or more physiological parameters sensing endpoint devices are configured to determine the one or more physiological parameters of each user. The one or more server devices comprises a data-obtaining subsystem, a data-processing subsystem, an operational parameter generation subsystem, a data recommendation subsystem, and a plurality of modules. The AI-based system is configured to process the obtained at least one of: the one or more physiological parameters and user-centric data to generate one or more user-centric operational parameters for controlling the operations of the one or more neuromodulation devices. The generation of one or more user-centric operational parameters optimizes neuromodulation therapy based on the user's unique physiologic parameters.

一种光交联聚乙二醇水凝胶材料、制备方法及应用

Absstract of: CN122608907A

本发明公开了一种光交联聚乙二醇水凝胶材料、制备方法及应用，其中，光交联聚乙二醇水凝胶材料，包括组分A和组分B，其中，组分A为乙烯基化自组装三肽修饰的聚乙二醇，组分B为光引发剂；组分A和组分B在水相介质中光照交联形成光交联聚乙二醇水凝胶材。本发明提供的一种光交联聚乙二醇水凝胶材料、制备方法及应用，该水凝胶通过将乙烯基化自组装短肽引入聚乙二醇大分子链端，构建了独特的“物理‑化学”双模态交联网络，其前体体系具备高度灵敏且温度可控的“溶胶‑凝胶”可逆转变特性，光交联后，短肽自组装形成的纳米增强网络结构，实现了材料力学和韧性的同步提升。

一种3D打印用聚乳酸/纳米羟基磷灰石复合线材及其制备方法与应用

Absstract of: CN122609030A

本发明涉及纳米复合材料技术领域，具体涉及一种3D打印用聚乳酸/纳米羟基磷灰石复合线材及其制备方法与应用。所述方法包括：S1、通过乳液溶剂挥发法制备不同平均粒径的聚乳酸/纳米羟基磷灰石复合微球；S2、将所述不同平均粒径的复合微球进行颗粒级配，获得级配原料；S3、将所述级配原料熔融挤出、牵引拉伸，得到复合线材。本发明通过复合微球化与颗粒级配相结合，有效实现了纳米羟基磷灰石在聚乳酸基体中的均匀分散，所得线材直径为1.75±0.03mm，纳米羟基磷灰石质量分数为3‑15%，断裂强度为37.52‑54.84MPa。该线材适用于FDM 3D打印，可用于制备骨修复支架，具有优异的生物相容性和力学性能。

一种脊柱矫形器设计方法

Absstract of: CN122604309A

本发明涉及脊柱矫形技术领域，特别是涉及一种脊柱矫形器设计方法。该方法通过脊柱矫形测量装置对患者顶椎区域施加梯度矫形力，测定额定矫形力与额定位移并建立实测数据库。同步采集患者 BMI、脊柱 Cobb 角、顶椎位置等关键参数，借助统计分析拟合得出多组参数间非线性二次函数关系，可快速推算出患者个性化矫正力学参数。将参数导入建模软件完成三维模型构建，再通过拓扑优化精简结构，最后利用 3D 打印技术完成矫形器制作。本发明建模精度高，所制矫形器贴合性好、矫正力度适配合理，兼顾使用安全性与矫治效果，制作流程简洁高效，可满足青少年特发性脊柱侧凸精准保守矫治的临床使用需求。

3D打印抗氧化稀土氧化物掺杂的骨修复支架及其制备方法

Absstract of: CN122605000A

本发明属于骨修复领域，具体涉及3D打印抗氧化稀土氧化物掺杂的骨修复支架及其制备方法。包括以下步骤：以PVA水溶液为基体，加入分散剂聚丙烯酸铵，得到用于纳米粉体的粘合剂溶液；将nHAp、nβ‑TCP与nREO经球磨混合后，与所述粘合剂溶液混匀，制得可 3D 打印的膏状浆料；导入支架三维模型，设置打印参数，采用气压挤出式 3D 打印得到支架素坯；将支架素坯经室温干燥后，在空气氛围中高温烧结，得到无有机成分的骨修复支架。本发明的制备方法所需原材料种类少，制备工艺受环境影响小。加入稀土氧化物后，支架具有较好的抗压强度、生物相容性和抗氧化能力，在用于骨修复植入的基础上，还可以用作生物3D打印载细胞支架和载药支架等，具有广阔的应用前景。

一种基于磁力驱动的分区式下颌与舌体前移矫治器及其制备方法

Absstract of: CN122604548A

一种基于磁力驱动的分区式下颌与舌体前移矫治器及其制备方法，包括由上矫治器和下矫治器组合形成的矫治器主体；所述矫治器主体包括利用负压使舌体前移以改善通气效果的前牙区矫治器和利用磁力给下颌提供下颌前移力的后牙区矫治器，前牙区矫治器包括用于防止口呼吸的弧状体，弧状体连接上矫治器和下矫治器形成一体式结构的矫治器主体；与现有技术相比，后牙区矫治器将磁铁应用于矫治器内部，通过调整相斥面角度及磁力大小，改变对牙列的应力分布，进行基于口颌系统生物力学仿真计算，获得最优的磁力大小和方向，为获得更加精准的磁力提供生物力学依据，以避免带来咬合关系改变和颞下颌关节紊乱等临床并发症，确保前移力的精准性与安全性。

一种兼具支撑的3D打印接骨板及其成型方法

Absstract of: CN122604477A

本发明属于匹配式3D打印支撑接骨板技术领域，公开了一种兼具支撑的3D打印接骨板及其成型方法。该接骨板为与截骨的撑开空白区角度匹配，并与骨面匹配式贴合，外形形态贴合骨骼轮廓，且具有支撑撑开空白区功能的三维的楔形支撑接骨板；该楔形支撑接骨板通过3D打印制成；楔形支撑接骨板包括：上表层上开设有多个用于促进轻量化设计的表层孔；表层孔的下部开设有经梯度变化孔径大于表层孔的用于提供强度力学支撑的内层孔；支撑接骨板本体的侧面开设有三维布设的多向斜向螺孔。本发明术前根据三维模型精确规划下肢力线与截骨撑开角度，结合个体化楔形支撑接骨板角度固定，保证力线矫正准确、支撑可靠，提高手术有效性与精准性。

METHOD AND APPARATUS FOR MANUFACTURING A SURGICAL GUIDE

Absstract of: KR20260126935A

서지컬 가이드 정보 생성 방법은 분석장치가 의료영상, 채취하려는 피판(Flap)에 대한 정보를 획득하는 단계; 상기 분석장치가 상기 획득한 의료영상을 기반으로 수술 영역의 3D 모델을 생성하는 단계; 및 상기 분석장치가 상기 3D 모델 및 상기 채취하려는 피판에 대한 정보를 기반으로 서지컬 가이드 정보를 생성하는 단계;를 포함한다.

一种富马酸酮替芬片及其制备方法

Absstract of: CN122604721A

本发明公开了一种富马酸酮替芬片及其制备方法，涉及药物制剂技术领域，所述制剂为环形结构且具有贯穿厚度的中心通孔，包括内核和包覆内核的pH敏感性外壳；内核由富马酸酮替芬原料药、协同助溶组分等经3D打印与梯度交联固化成型，外壳在口腔中抑制药物释放、在胃液中允许释放。制备方法包括打印墨水、复合凝固浴及梯度交联浴制备，3D打印成型，梯度交联固化，pH敏感层包覆及精准后处理。该制剂溶出速度快、脆碎度低、重量差异小、稳定性好且含量均匀，制备工艺精准可控，解决了传统制剂性能不佳的问题，适用于富马酸酮替芬的工业化生产。

一种3d打印复合陶瓷修复义齿制备工艺

Absstract of: CN122608408A

本申请涉及陶瓷义齿增材制造技术领域，具体公开了一种3d打印复合陶瓷修复义齿制备工艺。包括以下步骤：S1、干燥、煅烧得到核－壳结构氧化锆粉末；将核－壳结构氧化锆粉末与蒙脱土纳米片、导电金属氧化物亚微米球混合，得到电活性陶瓷复合粉末；S2、制备光固化打印浆料；S3、将光固化打印浆料通过光固化3D打印成型，进行热脱脂处理以去除有机树脂，得到多孔素坯；S4、制备致密化着色义齿坯体；S5、清洗致密化着色义齿坯体，得到3D打印复合陶瓷修复义齿。本申请的复合陶瓷修复义齿可用于口腔个性化修复体的定制制作，其具有在低温条件下同步实现坯体致密化与全层深度梯度着色的优点。

一种基于3D打印超透镜的颅内血管OCT成像导管

Absstract of: CN122604304A

本发明公开了一种基于3D打印超透镜的颅内血管OCT成像导管，属于医疗器械与光学成像技术领域。该导管包括：外壁封装套管、单模光纤、光学结构，集成于单模光纤远端端面，采用增材制造工艺直接构建。所述光学结构为3D打印光学结构或超透镜结构，被配置为实现光束的空间聚焦与传播方向的偏转，使出射光束以预设倾角从导管侧壁区域进行侧向发射，并补偿由导管聚合物材料及内部润滑介质所引起的像差。本发明通过将多功能光学元件直接集成于光纤末端，实现了紧凑化、一体化的光路设计，在≤0.7mm导管外径约束下同步实现高精度聚焦、可控侧向发射及多介质界面像差鲁棒补偿，显著提升了颅内远端血管OCT成像质量与临床适用性。

一种3D打印可降解仿生气管外支架及其制备方法

Absstract of: CN122604537A

本申请提供了一种3D打印可降解仿生气管外支架，包括高模量可降解材质外层以及低模量可降解材质弹性内层，外层与内层初始均为3D打印一体预制成型的板状形态，经热弯形围合后定型为适配气管壁的C形筒状，二者通过滑动结构实现相互不脱离的轴向滑动连接，内层可伴随气管壁轴向往复阻尼滑动与弹性复位以及径向与轴向伸缩耦合形变，同时采用内外壁双曲面结构，结合该功能分层构型、层间随动耦合形变的独创设计，可有效仿生人体气管天然生理曲度与力学特征；还提供了一种气管外支架制备方法，采用3D打印、热弯定型、滑动装配、静电纺丝修复层及无菌封装工艺，解决了现有技术支架力学性能矛盾、功能单一及量产受限等缺陷问题。

视频喉镜与患者电子病历的集成

Absstract of: WO2025117821A1

The technology relates to incorporating video laryngoscope data into the electronic medical record (EMR) of a patient. An example intubation system includes a patient terminal, a wireless hub, and a video laryngoscope. In an example method, the patient terminal accesses the electronic medical record of the patient; and receives, from the wireless hub wirelessly coupled to a video laryngoscope, intubation data generated by the video laryngoscope during an intubation procedure of a patient. The intubation data includes video data captured by the video laryngoscope and metadata for the video data generated by the video laryngoscope. The patient terminal then concurrently displays at least a portion of the intubation data with fillable fields of the electronic medical record; receives at least one interaction with the electronic medical record during the concurrent display; and stores the electronic medical record based on the at least one interaction.

精神健康モニタリングのための装置及び方法

Absstract of: KR102790003B1

Disclosed are an apparatus for monitoring mental health and an operating method thereof. According to an embodiment of the present invention, an operating method of an apparatus for monitoring mental health comprises the steps of: receiving passive data from a user device; extracting behavioral characteristic data of a patient from the passive data; predicting active data of the patient using a subjective emotional state prediction model learned from the behavioral characteristic data and active data; and monitoring mental health of the patient based on the predicted active data.

一种基于灯笼状柔性阵列的结肠电生理监测系统及肠炎智能评估方法

Absstract of: CN122604383A

0001 本发明公开了一种基于灯笼状柔性阵列的结肠电生理监测系统及肠炎智能评估方法，包括：柔性电极阵列，包含多个电极点并经激光切割形成若干纵向条带；可充气球囊导管，柔性电极阵列卷绕并固定于球囊外表面，在球囊充盈状态下，纵向条带被径向撑开，整体呈灯笼状，使各电极点从多角度共形贴附于结肠壁；信号采集模块，用于获取多通道结肠电生理信号；信号分析模块，用于进行多维分析，得出结肠健康程度的初步判断；再结合机器学习模型输出结肠炎症严重程度分级结果。本发明能稳定贴合结肠黏膜，并实现高质量监测结肠电生理信号，通过解析提取到的肠电信号多维特征识别肠道炎症，并与人工智能结合实现结肠炎症程度自动评估。

SYSTEMS AND METHODS FOR A SPINAL ANATOMY REGISTRATION FRAMEWORK

Absstract of: WO2026174314A1

Systems and methods are disclosed for automated C-arm guidance that convert image-level understanding into actionable gantry positioning. A keypoint detector trained on rotation-frame-aligned data identifies anatomical keypoints used to compute a gantry pose satisfying geometric view primitives. From an intra-operative fluoroscopic image and associated calibration data, a diffusion model determines three-dimensional geometry, seeds an archetype search, and emits error bounds that trigger intermediate fluoroscopic images when thresholds are exceeded. When no pre-operative three-dimensional imaging is available, population-based models refined by patient input parameters constrain geometry. A six-degree-of-freedom user interface renders sliders and proximity indicators using a sensor stack to converge on the computed pose. Non-rigid keypoint analysis with Random Sample Consensus detects discontinuities, while alignment characteristics derived from vertebra and orthopedic standardized rotation frames provide spinopelvic metrics and distal-to-distal relationships.

AUTOMATIC DENTAL IMPLANT PLANNING

Absstract of: WO2026171880A1

Automatic dental implant planning A computer-implemented method for virtually planning a position and orientation of a dental implant model in a jawbone region of an augmented maxillofacial model, including volumetric image data representing a portion of the maxillofacial anatomy and a virtual crown contour. The model is generated with volumetric image data, by identifying in the image data at least a portion of said jawbone region, and providing a shape, position and orientation of the virtual crown contour for a possible crown surface of a dental restoration for replacing a missing or to be extracted tooth. An initial positioning for said dental implant model is estimated, indicating a buccal, crestal and lingual surface of said identified jawbone portion. The distances between a top position of the dental implant model and the crestal bone surface are optimized, also between the dental implant model surface and the buccal and lingual surfaces of the jawbone portion.

MULTIMODAL AGENTIC MEDICATION AND HEALTH ENVIRONMENT INTERACTIVE DEVICE (EID)

Absstract of: WO2026174166A1

Provided herein is a medication and health environmental interactive device (EID), functional through its interactions with external environments and internal environments as a singular and/or part of a comprehensive medication management system, wherein it contains a medication and health EID and/or functions with provisioned network communication systems and cloud servers housing a health portal with electronic applications, which manages health and medication-related conditions as an agentic artificial intelligence health and medication management system. Additionally, the device consists of a medication enclosure for receiving medications within a medication inner-container and/or medication bottle, connects to a multifunctional cap for removal, dispensing, and preserving medications, and wherein the outer- container is a SMART medication container functioning as a personalized health and medication management system through power and electronics systems, integrative taxonomy classification systems, compliance and behavioral modification systems. Also provided are coding systems for quality of care and utilization of care of patients.

DIGITAL ASSESSMENT OF COGNITIVE FUNCTION

Nº publicación: WO2026171827A1 20/08/2026

Applicant:

HOFFMANN LA ROCHE [CH]
HOFFMANN LA ROCHE [US]
F. HOFFMANN-LA ROCHE AG
HOFFMANN-LA ROCHE INC.

Absstract of: WO2026171827A1

There is described a computer-implemented method for assessing the cognitive function of a subject. The method comprises: obtaining subject data that has been collected by carrying out a digital cognitive function test method. The digital cognitive function test method comprises: providing a user interface to the subject; presenting the subject, via the user interface, with a first sequence of images and a sequence of spatial direction indicators, wherein each image of the first sequence of images depicts a respective object and is presented together with a corresponding one of the spatial direction indicators of the sequence of spatial direction indicators; presenting the subject, via the user interface, with a second sequence of images, wherein the second sequence of images comprises a plurality of images that were previously presented to the subject in the first sequence of images, and wherein the images of the second sequence of images are ordered differently to the images of the first sequence of images; and receiving, from the subject via the user interface, image-direction data indicative, for each image of the second sequence of images, of a spatial direction indicator recalled by the subject as having been previously presented together with said image. The subject data comprises the image-direction data. The method further comprises determining, from the subject data, the value of one or more digital biomarkers, the one or more digital biomarkers being indicative of