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INTEGRATED AI-POWERED ADAPTIVE ROBOTIC SURGERY SYSTEM

Resumen de: US2025359955A1

A robotic surgical system includes a robotic manipulator configured to perform surgical procedures under direct surgeon control. A surgical camera system captures real-time intraoperative video. An external imaging interface receives multimodal imaging data, including preoperative and intraoperative data from at least one of magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, and fluoroscopy. An artificial intelligence (AI module has a trained neural network and a deep learning model trained on multi-institutional annotated surgical datasets, The AI module is configured to execute one or more of: fuse acquired video and imaging data into temporally and spatially coherent anatomical visualizations; generate continuously updating overlays aligned with the surgical field, with segmented anatomical features; projected tissue boundaries, proximity indicators for instruments, and predictive deformation trends; provide dynamic predictive trend visualization indicating zones of future anatomical complexity or risk; register and align preoperative imaging data with intraoperative imaging data in real time; adapt overlay presentation in response to tissue deformation without actuating the robotic manipulate or; and passively augment visual feedback without initiating any autonomous actuation of surgical instruments.

SUBGRAPH PATTERN EXTRACTION

Resumen de: US2025363328A1

Aspects of the disclosed technology provide solutions for extracting subgraph patterns in graph-structured data and encoding them as embeddings using a graph neural network (GNN). In some aspects, a process of the disclosed technology can include steps for receiving an input graph comprising a plurality of nodes and edges, the input graph representing relationships among a plurality of entities, parameterizing a graph neural network model based on a set of pattern graphs, and identifying, for at least a portion of the nodes in the input graph, rooted homomorphisms between the pattern graphs and local subgraphs rooted at the respective nodes. Systems and machine-readable media are also provided.

PREDICTING PROPERTIES OF PROTEINS AND LIGANDS

Nº publicación: EP4654205A1 26/11/2025

Solicitante:

ISOMORPHIC LABS LTD [GB]
Isomorphic Labs Limited

Resumen de: EP4654205A1

Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for generating a predicted property score of a protein and a ligand. In one aspect, a method comprises: obtaining a network input that characterizes a protein and a ligand; processing the network input characterizing the protein and the ligand using an embedding neural network to generate a protein-ligand embedding representing the protein and the ligand, wherein the embedding neural network has been jointly trained with a generative model that is configured to: receive an input protein-ligand embedding; and generate, while conditioned on the input protein-ligand embedding, a predicted joint three-dimensional (3D) structure of an input protein and an input ligand represented by the input protein-ligand embedding; and generating a property score that defines a predicted property of the protein and the ligand using the protein-ligand embedding.