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LastUpdate Última actualización 15/01/2026 [07:39:00]
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Solicitudes publicadas en los últimos 60 días / Last 60 days publications
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G9A/EHMT2 INHIBITOR USE FOR PRADER-WILLI SYNDROME

NºPublicación:  WO2025240956A1 20/11/2025
Solicitante: 
YALE UNIV [US]
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI [US]
YALE UNIVERSITY,
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
WO_2025240956_PA

Resumen de: WO2025240956A1

Described is small molecule 6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)-4-(tetrahydro-2H-pyran-4-yl)quinolin-2-amine (MS152) that inhibits methyltransferases G9a/EHMT2. This inhibitor can be used for the treatment of patients with G9a/EHMT2 related diseases such as Prader-Willi Syndrome and Alzheimer's Disease. Formula (I).

METHODS AND COMPOSITIONS FOR SCREENING AND TREATING ALZHEIMER'S DISEASE

NºPublicación:  EP4649317A2 19/11/2025
Solicitante: 
POPULATION BIO INC [US]
Population Bio, Inc
US_2024310389_PA

Resumen de: US2024310389A1

This document provides methods and materials related to screening for and treating Alzheimer's disease (AD), including late-onset Alzheimer's disease (LOAD).

Composition for improving obesity cognitive function and memory and preventing Alzheimer's disease comprising fermented hemp seed as an active ingredient

Nº publicación: KR20250161440A 17/11/2025

Solicitante:

강원대학교산학협력단주식회사퓨처에프바이오텍

WO_2025234537_PA

Resumen de: WO2025234537A1

The present invention relates to a food composition for improving obesity or cognitive function, comprising a hemp seed fermentate prepared using the Pediococcus acidilactici SRCM201591 strain. The fermentate was confirmed for radical scavenging ability, ROS scavenging ability, and AChE inhibitory ability, and found to have an antioxidant effect as a high content of polyphenol was measured. An anti-obesity effect was also confirmed through assays for triglyceride inhibition and C. elegans size reduction, and antioxidant and anti-obesity related gene regulation effects were identified following administration of the fermented extract. Accordingly, the fermentate can be advantageously used in the manufacture of food for improving obesity or cognitive function.

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