Resumen de: WO2025240956A1
Described is small molecule 6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)-4-(tetrahydro-2H-pyran-4-yl)quinolin-2-amine (MS152) that inhibits methyltransferases G9a/EHMT2. This inhibitor can be used for the treatment of patients with G9a/EHMT2 related diseases such as Prader-Willi Syndrome and Alzheimer's Disease. Formula (I).
Resumen de: US2024310389A1
This document provides methods and materials related to screening for and treating Alzheimer's disease (AD), including late-onset Alzheimer's disease (LOAD).
Nº publicación: KR20250161440A 17/11/2025
Solicitante:
강원대학교산학협력단주식회사퓨처에프바이오텍
Resumen de: WO2025234537A1
The present invention relates to a food composition for improving obesity or cognitive function, comprising a hemp seed fermentate prepared using the Pediococcus acidilactici SRCM201591 strain. The fermentate was confirmed for radical scavenging ability, ROS scavenging ability, and AChE inhibitory ability, and found to have an antioxidant effect as a high content of polyphenol was measured. An anti-obesity effect was also confirmed through assays for triglyceride inhibition and C. elegans size reduction, and antioxidant and anti-obesity related gene regulation effects were identified following administration of the fermented extract. Accordingly, the fermentate can be advantageously used in the manufacture of food for improving obesity or cognitive function.