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Resultados 153 resultados
LastUpdate Última actualización 04/05/2025 [07:29:00]
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Solicitudes publicadas en los últimos 60 días / Last 60 days publications
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BENZOTHIOPHENE COMPOUND

NºPublicación:  EP4516792A1 05/03/2025
Solicitante: 
KYOTO PHARMA IND [JP]
Kyoto Pharmaceutical Industries, Ltd
TW_202345792_PA

Resumen de: EP4516792A1

The present invention aims to provide a medicament capable of treating and/or preventing diseases associated with oxidative stress by inhibiting the protein-protein interaction between Keap1 and Nrf2 and activating Nrf2. The present invention relates to a compound represented by the following formula (1):wherein each symbol is as described in the DESCRIPTION,or a pharmaceutically acceptable salt thereof. In addition, the present invention also relates to a medicament containing the compound, for the prophylaxis and/or treatment of diseases involving oxidative stress selected from the group consisting of chronic kidney disease, non-alcoholic steatohepatitis, chronic obstructive pulmonary disease, radiation skin disorder, radiation mucosal disorder, cardiac failure, pulmonary arterial hypertension, Parkinson's disease, Friedreich's ataxia, multiple sclerosis, age-related macular degeneration, retinitis pigmentosa and glaucoma.

NICOTINAMIDE RIBOSIDE DOSAGE REGIMEN FOR TREATING PARKINSON'S DISEASE

NºPublicación:  EP4514362A1 05/03/2025
Solicitante: 
VESTLANDETS INNOVASJONSSELSKAP AS VIS [NO]
VESTLANDETS INNOVASJONSSELSKAP AS (VIS)
WO_2023209010_PA

Resumen de: WO2023209010A1

The present invention generally relates to the treatment of Parkinson's disease (PD) in humans. More particularly, it relates to nicotinamide riboside (NR) for use in a method for treatment of Parkinson's disease in a human subject characterized by a particular dosage regimen; pharmaceutical compositions; and dosage forms, which can be for use in or as treatment of Parkinson's disease.

CRYSTAL FORM OF BLARCAMESINE HYDROCHLORIDE, METHOD FOR PREPARING SAME, AND USE THEREOF

Nº publicación: EP4516782A1 05/03/2025

Solicitante:

CRYSTAL PHARMACEUTICAL SUZHOU CO LTD [CN]
MOEHS IBERICA SL [ES]
Crystal Pharmaceutical (Suzhou) Co., Ltd,
Moehs Iberica SL

EP_4516782_PA

Resumen de: EP4516782A1

The present disclosure relates to novel crystalline forms of Blarcamesine hydrocholoride (hereinafter referred to as "compound I"), a method for preparing same, a pharmaceutical composition comprising the crystalline forms, and use of the crystalline forms in preparing a Sigma-1 receptor agonist and a medicament for treating Rett syndrome, Alzheimer's disease, and Parkinson's disease dementia.

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