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耳模制造方法、装置、系统、设备及存储介质

Resumen de: CN121018947A

本申请提供了一种耳模制造方法、装置、系统、设备及存储介质，涉及生物医疗技术领域，本申请预先对目标对象的耳郭取模得到耳郭反向模型，该耳郭反向模型真实表达了耳郭的所有曲面信息，通过扫描该耳郭反向模型得到三维点云数据，并基于三维点云数据构建得到的数字化耳郭正向模型，消除了耳部隐蔽曲面轮廓对点云数据采集的影响，有效实现了对耳郭完整曲面的数字化提取，提高了数字化构建实现耳模的精度，从而保证了数字化耳模与目标人员的耳部的契合度，并依据预设和提取耳郭的穴点信息，进行开孔，然后进行数字化耳模的实物打印，进行适合佩戴，方便进行个性化移动化诊治调理，实现了耳模数字化构建和可移动个性诊治调理的创新全流程。

一种钛基复合材料的制备方法

Resumen de: CN121023285A

本发明公开了一种钛基复合材料的制备方法，该方法包括以下步骤：一、将氧化石墨烯分散液加入聚乙烯吡咯烷酮溶液中混合均匀，滴加硝酸银溶液进行自发反应，得到氧化石墨烯/纳米银复合粉末溶液；二、在氧化石墨烯/纳米银复合粉末溶液中加入钛或钛合金粉末，加热并进行超声机械搅拌，干燥后得到氧化石墨烯/纳米银+钛混合粉末；三、将氧化石墨烯/纳米银+钛混合粉末进行3D打印，得到钛基复合材料。本发明的制备方法通过在钛基表面构建氧化石墨烯和纳米银的共分散纳米结构，得到的钛基复合材料具有晶粒细化、高抗菌性、高耐磨性及高综合力学性能的特点，适用于医用钛及钛合金材料技术领域。

适用于DLP 3D打印技术的齿科修复用复合材料及其制备方法

Resumen de: CN121015460A

本发明属于齿科陶瓷材料技术领域，具体涉及适用于DLP 3D打印技术的齿科修复用复合材料及其制备方法。所述的齿科修复用复合材料包括以下重量份数的原料：聚硅氮烷陶瓷先驱体粘结剂：30‑50份；氧化锆：60‑90份；光引发剂：3‑7份；热引发剂：2‑5份；分散剂：2‑6份；流变剂：1‑5份；硅烷偶联剂：3‑8份；烧结助剂：5‑10份；采用聚硅氮烷先驱体材料，通过光固化精确成型，再经热处理后可控转化为无机陶瓷，兼具有机物的加工性与陶瓷的高耐温、高稳定性，克服了传统有机粘结剂在高温下易分解、收缩大、强度不足的问题，为高性能陶瓷器件制备提供了新材料基础。

交联剂和组合物

Resumen de: US2024352174A1

The present disclosure provides cross-linker compounds that can produce desirable polymeric materials, polymer compositions, and/or photo-curable resins. Further provided herein are methods of producing cross-linker compounds, compositions, resins, devices, and polymeric materials. Also provided herein are methods of using cross-linker compounds, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.

复合3D环保打印材料的人体肋骨骼替代物制造方法、设备、存储介质

Resumen de: CN121018950A

本发明涉及复合3D环保打印材料的人体肋骨骼替代物制造方法、设备、存储介质，包括：步骤S100.基于患者受伤处的肋骨扫描，输出肋骨数据；步骤S200.在医学图像处理软件中基于所述肋骨数据生成肋骨三维模型；步骤S300.通过三维建模软件对肋骨三维模型进行优化，所述优化至少包括模型预处理、切片参数调整、打印路径规划和填充策略；步骤S400.将聚乳酸与连续纤维通过熔融堆叠形成复合材料，复合材料作为人体肋骨替代物的3D打印材料；步骤S500.采用3D打印技术对所述肋骨三维模型进行打印；步骤S600:对打印的人体肋骨骼替代物进行力学实验测试。

DENTAL DEVICE MANUFACTURING SYSTEM AND METHOD

Resumen de: US2025359966A1

A manufacturing system and method obtain a first digital model of teeth, create a modified digital model of the teeth by adding a locator feature to the first digital model of the teeth, and create a physical model of the teeth based on the modified digital model. A portion of the physical model is created based on the locator feature. A dental aligner device is formed on the physical model of the teeth with extraneous material of the dental aligner device extending away from the dental aligner device. The extraneous material is removed from the dental aligner device from the physical model of the teeth. The forming of the dental aligner device and/or the removing of the extraneous material is performed by positioning the physical model using the locator feature.

DEVICES AND METHODS FOR STENT GRAFT EXTRACTION

Resumen de: US2025360010A1

A method of extracting an implant from a vessel includes inserting an extraction device into the vessel. The extraction device includes a hollow body having a cylindrical portion and a bellowed portion. An inner diameter of the bellowed portion increases toward an end of the hollow body. The method also includes sliding the extraction device over an outer surface of the implant such that the hollow body slides between a vessel wall and the implant to move the implant from a deployed position to a non-deployed position within the hollow body. The method can also include removing the extraction device and the implant from the vessel.

MANUFACTURING PROCESSES FOR BIOPOTENTIAL-BASED WRIST-WEARABLE DEVICES AND RESULTING MANUFACTURED BIOPOTENTIAL-BASED WRIST-WEARABLE DEVICES

Resumen de: US2025362752A1

A wrist-wearable device is described herein. The wrist wearable device includes a first skin-contact portion. The first skin contact portion (i) is coupled with a first set of biopotential-signal sensors for detecting first biopotential signals that are provided to a first flexible printed circuit board, and (ii) is coupled with an elastic material that extends beyond an end of the first skin-contact portion. The wrist wearable device includes a second skin-contact portion that is separated from the first skin-contact portion by a capsule structure. The second skin-contact portion is (ii) coupled with a second set of biopotential-signal sensors for detecting biopotential signals that are provided to a second flexible printed circuit board, and (ii) is coupled with a receiving loop for receiving the elastic material to affix the band to a body part of a wearer of the wrist-wearable device.

Method of Designing and Manufacturing an Elastic Circumferential Rim of a Prosthetic or Orthotic Device

Resumen de: US2025360004A1

A method of designing and manufacturing an elastic circumferential rim of a prosthetic or orthotic device includes a step of creating a basic structure of the elastic circumferential rim based on the type of the prosthetic or orthotic device. Requirements are determined for stiffness of the elastic circumferential rim in the individual areas along the circumference of the elastic circumferential rim. A structural model of the elastic circumferential rim is created based on the requirements for stiffness of the elastic circumferential rim in the individual areas along the circumference of the elastic circumferential rim and the basic structure of the elastic circumferential rim. The elastic circumferential rim is manufactured based on the structural model of the elastic circumferential rim.

PART FOR COVERING A BONE DEFECT

Resumen de: WO2025242824A1

The present invention relates to a method for manufacturing a covering part for a device intended for bone regeneration, in order to cover a bone defect in a patient, which method comprises the steps of a) recording a set of data representative of the stated bone defect in three dimensions; b) designing the covering part using this set of data, which covering part has a wall opposite the bone defect and a wall facing the bone defect, and which covering part is able to be fastened in place on a bone by at least one fastening means; and c) manufacturing the covering part, wherein the covering part is made from a resorbable polymer by 3D printing, has microperforations, and has a thickness of between 0.8 and 1.5 mm.

BIOSYMBIOTIC SYSTEMS FOR CHRONIC LONG-RANGE MONITORING OF BIOSIGNALS IN LIMITED RESOURCE SETTINGS

Resumen de: AU2024273563A1

The present disclosure provides a wearable article including a 3D printed base, 3D printed antenna ground plane structure and a 3D printed a dipole antenna structure, wherein the base, ground plane structure and dipole antenna structure comprises a 3D printed mesh which is formed of a stretchable elastomeric polymer material. The wearable article also includes signal transmission and power harvesting circuitry comprising duplexing circuit to transmit and receive data and to receive wireless power from a power transmission unit.

ADDITIVELY MANUFACTURED APPLIANCES WITH CELLULAR STRUCTURES

Resumen de: US2025359967A1

Intraoral appliances and associated systems are provided. In some embodiments, an intraoral appliance includes a 3D printed body composed of a plurality of additively manufactured layers. The 3D printed body can include a first cellular structure located at one or more first areas of the intraoral appliance, the first cellular structure corresponding to a first stiffness, and a second cellular structure located at one or more remainder areas of the intraoral appliance, the second cellular structure corresponding to a second stiffness less than the first stiffness.

ORAL DRUG DOSAGE FORMS FOR STOMACH RETENTION

Resumen de: US2025360081A1

Provided herein are drug dosage forms designed to provide a desired retention in an individual based on geometric differences between a pre-administration and post-administration state of the dosage form. In certain aspects, provided are oral drug dosage forms comprising a swellable and expandable material configured, upon swelling or expanding, to drive expansion of the overall size of the oral drug dosage forms such that the oral drug dosage forms are retained in the stomach for a desired period of time. In certain other aspects, provided is directed to components useful for the oral drug dosage forms taught herein. In certain other aspects, provided is directed to methods of designing, methods of making, such as involving three-dimensional (3D) printing, injection molding, ultrasonic welding, or any combination thereof, commercial batches, and methods of delivering a drug to an individual comprising administering an oral drug dosage form taught herein.

RADIATION-CURING COMPOSITION FOR THE PRODUCTION OF DENTAL COMPONENTS

Resumen de: US2025361406A1

The invention relates to a radiation-curing composition for the manufacture of dental components using the DLP process or SLA process, comprising, based on the total mass of the radiation-curing composition (i) one or more radically polymerizable monomers in a combined mass fraction of 60% or more, (ii) one or more hexaarylbiimidazole compounds in a combined mass fraction in the range of 0.1 to 5%, and (iii) one or more mercaptotetrazole compounds in a combined mass fraction in the range of 0.1 to 5%, wherein the combined mass fraction of fillers in the radiation-curing composition is less than 30%.

REINFORCED ENGINEERED CELLULARIZED-TISSUE

Resumen de: US2025361480A1

A method for generating reinforced engineered cellularized construct, which utilizes a biocompatible small-molecule reinforcing agent that do not affect the viability of the cells, a reinforced engineered cellularized construct obtained thereby and used the engineered cellularized construct are provided.

3D PRINTING OF ORGANOID SLURRIES

Resumen de: WO2025245459A1

A method for preparing a tissue, comprising depositing a cell bioink in a biocompatible matrix to form a printed cell structure in the biocompatible matrix; and allowing the printed cell structure to incubate in the biocompatible matrix for a time sufficient for at least a portion of cells of the printed cell structure to develop into a contiguous tissue before removing the printed cell structure from the biocompatible matrix; wherein the biocompatible matrix has a yield stress greater than a yield stress of the cell bioink, prior to depositing the cell bioink in the biocompatible matrix, and the biocompatible matrix optionally comprises a rheological modifier.

ZINGEROL-BASED BIODEGRADABLE POLYESTERS AND 3D-PRINTABLE PHOTOPOLYMERIZABLE COMPOSITIONS, METHODS OF PREPARATION, AND USES THEREOF

Resumen de: US2025361358A1

The present invention provides novel polymeric materials for biomedical applications, derived from plant-derived phenolic diols, primarily zingerol. Two material classes are disclosed. First, biodegradable polyesters using said diols, are synthesized via solvent/catalyst-free melt polycondensation. These exhibit tunable mechanical properties, shape memory, antibacterial activity, and biocompatibility. Second, photopolymerizable zingerol derivative monomers or crosslinkers, are formulated into resins for 3D printing. Resulting 3D objects offer tailored mechanics, biodegradability, excellent shape memory, cytocompatibility, hemocompatibility, and potent antioxidant, antibacterial, and anti-biofilm functions. Methods for preparing both polymer types and their derivatives, alongside uses in tissue engineering and medical implants, are described.

POLYMER-PHOSPHATE-BASED COMPOSITION FOR 3D PRINTED IMPLANTS

Resumen de: EP4653024A1

The invention provides a composition for low-temperature 3D printing of tissue implants, which contains:- calcium phosphate powder,- chitosan particles,- aqueous solution of block copolymer (D,L-polylactide-co-polyglycolide)-b-poly(ethyleneglycol)-b-(D,L-polylactide-co-polyglycolide) (PLGA-PEG-PLGA).A kit and a method for preparing the composition are provided, as well as a method for printing tissue implants using the kit.

RADIATION-CURABLE COMPOSITION FOR THE PRODUCTION OF DENTAL COMPONENTS

Resumen de: EP4652981A1

Die Erfindung betrifft ein eine strahlungshärtende Zusammensetzung für die Herstellung dentaler Bauteile im DLP-Verfahren oder SLA-Verfahren, umfassend bezogen auf die Gesamtmasse der strahlungshärtenden Zusammensetzung: i) ein oder mehrere radikalisch polymerisierbare Monomere in einem kombinierten Massenanteil von 60 % oder mehr, ii) eine oder mehrere Hexaarylbiimidazol-Verbindungen in einem kombinierten Massenanteil im Bereich von 0,1 bis 5 %, und iii) eine oder mehrere Mercaptotetrazol-Verbindungen in einem kombinierten Massenanteil im Bereich von 0,1 bis 5 %, wobei der kombinierte Massenanteil an Füllstoffen in der strahlungshärtenden Zusammensetzung weniger als 30 % beträgt.

METHOD AND APPARATUS FOR GENERATING DIGITAL MODEL OF CORRECTIVE DEVICE, AND MANUFACTURING METHOD FOR CORRECTIVE DEVICE

Resumen de: EP4652960A1

A method for generating a digital model of an orthodontic appliance, which comprises: determining overall size information and alveolar size information for a digital model of an orthodontic appliance according to information related to different dentition areas of a target oral cavity digital model; and generating the digital model of the orthodontic appliance according to the overall size information and the alveolar size information. Further provided are an apparatus for generating a digital model of an orthodontic appliance using the method for generating a digital model of an orthodontic appliance, as well as an orthodontic appliance manufactured using the method for generating a digital model of an orthodontic appliance. The method for generating a digital model of an orthodontic appliance can improve production efficiency and product precision of orthodontic appliances.

MULTIVASCULAR NETWORKS AND FUNCTIONAL INTRAVASCULAR TOPOLOGIES WITHIN BIOCOMPATIBLE HYDROGELS

Resumen de: EP4653192A2

A device made from a hydrogel matrix is provided. The hydrogel matrix includes a photoabsorber with a void architecture in the matrix, having a first vessel architecture and a second vessel architecture that are each tubular and branching, wherein the first and second vessel architectures are fluidically independent from each other. A pre-polymerization solution for forming the device, and methods of fabricating such devices are described. A method of fabricating a 3D hydrogel construct is provided. The method includes using a computer-implemented process to create a 3D model of the construct based on a tessellation of polyhedra having a number of faces connected by edges and vertices, generate a first vascular component of the model, generate a second vascular component of the model, and combine the first and second vascular components of the model.

用于增材制造的模块化构建平台

Resumen de: US2024100775A1

Systems, methods, and devices for additive manufacturing are provided. In some embodiments, a method includes: coupling a plurality of build platforms to a carrier; forming a plurality of 3D objects on the plurality of build platforms using an additive manufacturing process, where each build platform receives at least one 3D object thereon; removing the plurality of build platforms from the carrier; performing post-processing of the plurality of 3D objects while the 3D objects remain on the respective build platforms; and separating the plurality of 3D objects from the respective build platforms.

一种牙套热压膜及其制备方法

Resumen de: CN121005881A

本发明公开了一种牙套热压膜的制备方法。该热压膜先对苯二甲酸通过单氯甲基化进行季铵化反应，再与改性乙二醇单体单体进行共聚反应形成改性后的聚酯，最后与季戊四醇反应得到星形交联的聚对苯二甲酸乙二醇酯；得到所需材料后，通过仪器获取口内数字模型并3D打印牙颌模型；采用一体式热压成型工艺将产物热压成型后，裁剪打磨抛光，得到牙套热压膜。本发明力学性能与弹性优势并存，拉伸强度30‑40MPa，断裂伸长率≧8%，玻璃化温度在60℃到70℃之间，结构稳定且抗菌效果好，对常见细菌杀灭率超96%。采用3D打印与热压成型结合，提升生产效率与精度，产品透明美观、方便摘戴，兼具化学稳定性，适合规模化生产。

一种用于建立骨不连动物模型的隔离器及其制备方法

Resumen de: CN121006015A

本发明公开了一种用于建立骨不连动物模型的隔离器及其制备方法，涉及医疗器械技术领域，包括如下步骤：步骤一：得到侧链含有Si‑H键的含氢硅油预聚物；步骤二：得到侧链带环氧基的硅胶大分子单体；步骤三：得到抗炎功能化硅胶大分子单体；步骤四：三维重建骨骼模型，创建缺损处隔离器模型；步骤五：将步骤三中得到的抗炎功能化硅胶大分子单体与活性稀释剂加入配料罐，机械搅拌下加入交联剂，加入聚醚改性聚二甲基硅氧烷，搅拌30分钟，在500Pa真空下脱泡2小时，脱泡后暗室中静置熟化；步骤六：采用多料盒DLP光固化3D打印机进行隔离器打印，本发明从根本上减少了对骨不连病理过程的观察干扰，实现了高保真建模构建。

FREMGANGSMÅDE OG INDRETNING TIL DATAMATCHING AF ORAL MODEL

Nº publicación: DK4101407T3 24/11/2025

Solicitante:

OSSTEM IMPLANT CO LTD [KR]
Osstem Implant Co., Ltd

Resumen de: US2023076682A1

The present disclosure relates to a method and device for matching oral model data that can provide matching points to a user to match oral model data and computerized tomography (CT) data even for edentulous patients. In this way, convenience is increased and matched data can be effectively generated even for edentulous patients for whom matching has been difficult conventionally.