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DEEP REINFORCEMENT LEARNING BASED ROBUST NEUROVASCULAR MAPPING

Resumen de: US20260105597A1

Systems and methods for generating a patient-specific vascular tree are provided. 1) one or more medical images of a patient and 2) a vascular tree template comprising a plurality of points are received. The plurality of points of the vascular tree template are iteratively adjusted based on the one or more medical images using one or more AI (artificial intelligence) agents to generate a patient-specific vascular tree for the patient. The patient-specific vascular tree is output.

SMART RING DEVICE FOR IDENTIFYING POSTURE OF USER

Resumen de: WO2026079901A1

According to an embodiment, a smart ring device may comprise a housing comprising a first surface for contacting a portion of a user's body and a second surface opposite to the first surface. The housing may comprise a conductive portion disposed to surround the portion of the user's body along the second surface. The smart ring device may comprise: a radio frequency (RF) coupler connected to the conductive portion; a memory including instructions and including one or more storage media; and at least one processor including a processing circuit. The instructions, when executed individually or collectively by the at least one processor, may cause the smart ring device to obtain impedance information about the conductive portion on the basis of a feedback signal obtained through the RF coupler while a signal is transmitted or received through the conductive portion. The impedance information may be used as input data for an artificial intelligence model configured to identify the posture of the portion of the body.

MEDICAL DEVICE

Resumen de: WO2026079016A1

A medical device 1 is used with a consumable 2 attached thereto. The consumable 2 has a usage time limit stipulated, and the consumable 2 has an information presentation unit 21 for presenting individual identification information of the consumable 2. The medical device 1 includes a reading unit 3 for reading the individual identification information from the information presentation unit 21, and a consumable management unit 41 that, on the basis of the individual identification information presented by the information presentation unit 21, monitors usage time of the consumable 2 and determines whether the usage time of the consumable 2 has reached the usage time limit.

SYSTEMS AND METHODS FOR WIRELESS COMMUNICATIONS IN AN ANALYTE MONITORING SYSTEM

Resumen de: WO2026080213A1

Aspects of the present disclosure provide techniques for adapting an advertisement rate at which advertisement messages are transmitted by an analyte sensor system. An example method performed by the analyte sensor system includes transmitting first advertisement messages according to a first advertisement rate, establishing a connection with a display device based on the first advertisement messages, receiving, from the display device after establishing the connection, a message requesting the analyte sensor system use a second advertisement rate, determining the second advertisement rate based on the message, terminating the connection with the display device, transmitting, after the connection with the display device is terminated, second advertisement messages according to the second advertisement rate, and reestablishing the connection with the display device based on the second advertisement messages. Other aspects relate to adapting measurement data transmission rates and authentication/authorisation of display devices and encryption of (re-)established connections.

SYSTEMS AND METHODS FOR VOICE EVALUATION

Resumen de: WO2026080579A1

An artificial intelligence based voice evaluation system designed to improve the diagnosis and treatment of vocal disorders. The artificial intelligence based voice evaluation system utilizes machine learning to provide real-time analysis of aerodynamic and acoustic data corresponding to user vocal health. The artificial intelligence based voice evaluation system is operable to monitor a vocal health of a user and to generate at least one recommendation based on the user vocal health data.

METHODS AND SYSTEMS TO INDUCE REFLECTION BASED ON EMOTIONAL VALENCE

Resumen de: WO2026080830A1

Methods and systems to induce reflection based on emotional valence are provided. A digital communications network (DCN) is provided to a plurality of members of a population to communication with each other. A first communication is transmitted to an individual member of the plurality of members and a first response is received from the individual member. The first response is analyzed to determine a first level of emotional valence and a second communication is generated and designed to induce reflection in the individual member for a first time. The second communication is transmitted to the individual member and a second response is received. The second response is analyzed to determine a second level of emotional valence.

SYSTEM AND METHOD FOR MANUFACTURING AN X-RAY BONE PHANTOM

Resumen de: US20260102135A1

A computer-implemented method for manufacturing an X-ray bone phantom is provided. The computer-implemented method includes obtaining, via a processing system comprising one or more processors, dual-energy scan data from one or more dual-energy scans of an ex vivo bone phantom. The computer-implemented method also includes converting, via the processing system, the dual-energy scan data into a two-dimensional image. The computer-implemented method further includes printing, via the processing system, a semi-anthropomorphic X-ray bone phantom made of aluminum based at least on the two-dimensional image, wherein the semi-anthropomorphic X-ray bone phantom is configured to provide quantitative areal bone mineral density and a realistic projected bone morphology for image quality assessment and lateral distance measurements during calibration.

PROCESS OF DESIGNING AND MANUFACTURING AN ORTHOTIC OR PROSTHETIC DEVICE

Resumen de: WO2026077490A1

The object of the invention is a process of designing and manufacturing an orthotic or prosthetic device comprising a step of preparing a region of a surface (2) of a user's body intended for application of the device for scanning, a step of scanning the region of the surface (2) of the user's body for creating an initial digital model (3), a step of processing the initial digital model (3) to a modified digital model (4) and a step of manufacturing the orthotic or prosthetic device (1) based on the modified digital model (4). The step of preparing the region of the surface (2) of the user's body comprises fastening at least one shape element (5) to a part of the region of the surface (2) of the user's body intended for application of the device (1) for modification of the shape of the outer surface of the user's body in this part.

Mandibular Advancement Device (MAD) having adjustment features

Resumen de: US20260102276A1

0000 A dental article of manufacture comprising a first appliance, and a second appliance. The first appliance fits dentition of a patient’s lower dental arch, and the second appliance fits dentition of the patient’s upper dental arch. The first appliance has a first feature positioned at its midline and located at a given distal offset with respect to an incisal edge when fitted on the lower dental arch. Preferably, the second appliance has a second cooperating feature positioned at its midline and includes a closed cavity having a front-facing opening. The second feature is designed to mate with the first feature. To this end, the second feature is positioned to removably receive the first feature only through the facing opening. In use, the second feature retains the first feature in the closed cavity against backwards and up or down movement when the second appliance is fitted on the upper dental arch.

PRINTER FOR COSMETICS

Resumen de: WO2026079532A1

The present invention relates to a printer for cosmetics that can easily form clear design patterns on the surfaces of cosmetic materials, the printer for cosmetics comprising: a support part for supporting at least one cosmetic material; a header part that includes an ejection port for ejecting an ink composition onto the surface of the cosmetic material and is configured to reciprocate along a first direction; and a first heating part and a second heating part which have the header positioned therebetween and are arranged along a second direction that forms a predetermined angle with respect to the first direction.

SYSTEM AND METHOD FOR GENERATING AN APPLIANCE

Resumen de: US20260105213A1

In some embodiments systems and methods are provided for an automated system for generating an appliance for a body part that utilizes artificial intelligence and machine learning to identify points in a scan, generate a surface from the identified points, and generate the appliance for the body part.

眼科用レンズ及び型内変性によるそれらの製造

Resumen de: WO2024194792A1

A method for forming an ophthalmic lens including providing a mold assembly including base and front curve molds each having a surface profile and defining and enclosing a cavity therebetween having a reactive monomer mixture for making the lens and a first polymerization initiator that is activated at a first wavelength. A light transmissive one of the molds is exposed to a source of substantially uniform actinic radiation at the first wavelength according to a predetermined exposure pattern including at least one exposure portion and at least one non- exposure portion to initiate polymerization of the reactive monomer mixture within the mold at said at least one exposure portion. The lens is fully cured at the exposure portions and unreacted or non-gelled portions remain within the lens adjacent to the front and base mold halves, which are extracted following removal from the mold assembly, leaving one or more predetermined geometric indentations in the front and back surfaces of the lens such that the surface profile of the lens deviates from the surface profile of the respective front and back mold halves at the locations of the geometric indentations.

COMPOSITIONS AND METHODS FOR ADDITIVE MANUFACTURING OF PALATAL EXPANDERS

Resumen de: US20260102224A1

0000 Materials, methods, and systems for additive manufacturing are provided. In some embodiments, a method includes: forming a mixture including a first thermoplastic polymer powder separated from a first additively manufactured dental appliance manufactured during a first powder bed fusion process, where the first thermoplastic polymer powder has a characteristic particle size distribution and a characteristic melt volume rate; in a second powder bed fusion process, depositing a powder layer of the mixture, where the powder layer has a powder packing consistency dependent on the characteristic particle size distribution of the first thermoplastic polymer powder; and in the second powder bed fusion process, applying energy to the powder layer to melt the powder layer to form a part layer of a second additively manufactured dental appliance, where the part layer has a material consistency dependent on the characteristic melt volume rate of the first thermoplastic polymer powder.

COATING FOR METAL ALLOY

Resumen de: US20260103781A1

0000 A metal alloy that includes an enhancement coating material. The metal alloy includes rhenium and one or more additives. The enhancement coating is at least partially applied to the metal alloy by a physical vapor deposition (PVD) process, a chemical vapor deposition (CVD) process, an atomic layer deposition (ALD) process, a plasma-enhanced chemical vapor deposition (PE-CVD) process, ion implantation, direct energy deposition (DED), and/or thermal spray techniques like plasma arc spraying, flame spraying, high velocity oxy fuel spraying (HVOF). The enhancement coating is formed of a) 35-95 wt. % zirconium and wherein said enhancement coating includes ZrN, ZrNC, ZrOC or a combination of ZrN and ZrO2, b) 20-85 wt. % titanium and one or more of carbon, nitrogen, oxygen, rhenium, and silicon, c) 40-85 wt. % chromium and one or more of carbon, nitrogen, oxygen, rhenium, and silicon, or d) at least 60 wt. % carbon.

EXAMINING VISIBLE SKIN CONDITIONS

Resumen de: AU2025234210A1

A method for examining visible skin conditions is shown. A housing (101) is located at a region of a visible skin condition and image data of the skin over this region is captured. Electric fields (2001, 2002) are generated that penetrate the skin over the region, such that an application of the apparatus produces both image-related signals and electric field related signals for the same skin condition. Depth of skin penetration of the visible skin condition may be assessed by calculating the surface area of the visible skin condition from the image data and determining the volume of the visible skin condition from the electric field related signals and processing the calculated surface area in combination with the determined indication of volume to assess the depth of skin penetration. The electric field generating device may comprise a first dielectric substrate (301) having a hole (302) and the capturing step may be performed by a camera (501) viewing the visible skin condition through this hole. A method for examining visible skin conditions is shown. A housing (101) is located at a region of a visible skin condition and image data of the skin over this region is captured. Electric fields (2001, 2002) are generated that penetrate the skin over the region, such that an application of the apparatus produces both image-related signals and electric field related signals for the same skin condition. Depth of skin penetration of the visible skin condition may be assessed by cal

SLIDING ELEMENT, METHOD FOR PRODUCING THE SLIDING ELEMENT AND USE OF THE SLIDING ELEMENT

Resumen de: WO2026076477A1

The invention relates to a sliding element (1), in particular for medical components for use in implantology, comprising a substrate (3) and a biomaterial (2) applied to the substrate (3), which biomaterial provides a sliding layer (1a) on its side facing away from the substrate (3), wherein the substrate (3) has multiple cavities (7) on a connection surface (4) facing the biomaterial (2), wherein the cavities (7) are open in the direction of the sliding layer (1a) and at least 50% of the cavities (7) have an undercut (7a) in the direction of the interior of the substrate (3), wherein the substrate (3), in a first profile depth (a) of at least 0.6 μm, has a round-ridged roughness profile with an areal roughness characteristic Sa of less than 0.05 μm, wherein the substrate (3) has the multiple cavities (7) between the first profile depth (a) and a second profile depth (b), and wherein the second profile depth (b) measures at least 200 μm, preferably at least 350 μm.

METHOD FOR PROVIDING USER INTERFACE FOR MANUFACTURING PROSTHESIS, AND COMPUTER-READABLE RECORDING MEDIUM IN WHICH PROGRAM FOR EXECUTING SAME METHOD ON COMPUTER IS RECORDED

Resumen de: WO2026079533A1

This method for providing a user interface for manufacturing a prosthesis comprises: providing a guide image visualizing the inner surface of a prosthesis to be put on a prepared tooth; providing a parameter adjusting unit for adjusting a plurality of parameters for generating the prosthesis; displaying, on the guide image, a selected parameter image for explaining a parameter selected by a user from among the plurality of parameters; and generating a 3-dimensional image of the prosthesis on the basis of data set by the parameter adjusting unit.

MINIMALLY INVASIVE AND ENDOSCOPIC IN-VIVO BIOPRINTING SYSTEMS AND METHODS

Resumen de: AU2025215643A1

A system (100) may include a donor supply sub-system (110) configured to supply donor material (102) to a donor substrate (104). The system may include a material transfer sub-system (108) comprising a laser (200) configured to illuminate the donor substrate via a transfer beam (202). The system may include an instrument head (302) of a medical instrument (300) configured to house the donor substrate, wherein upon an illumination of the donor substrate, the donor material is transferred to receiver material in vivo.

OCULAR PHOTO-BIO-STIMULATION OPTICS

Resumen de: AU2024337161A1

A device providing ocular photo-bio-stimulation therapy, a biological technique to control or influence the activity of neurons or other cell types in, on or about the eye with light. As used herein ocular photo-bio-stimulation is an umbrella category of which photobiomodulation, optogenetics and phototherapy are forms thereof. The current invention relates, in part, to photobiomodulation therapy, which includes the utilization of nonionizing electromagnetic energy to trigger photochemical changes within cellular structures. The current invention relates, in part, to optogenetics. Optogenetics is a biological technique to control the activity of neurons or other cell types with light. The current invention relates, in part, to phototherapy, also known as light therapy or bright light therapy, which is a treatment that uses controlled exposure to artificial or natural light to treat medical conditions.

ARTIFICIAL-INTELLIGENCE TECHNIQUES FOR NEUROTOXICITY DETECTION

Resumen de: US20260106042A1

Detecting neurotoxicity associated abnormalities due to certain medication therapies can be significant for identifying various neurological disorders. The present disclosure relates to detection of neurotoxicity related disorders by leveraging an interface including one or more sets of queries and a set of components to receive a set of responses corresponding to the sets of queries. The techniques, as disclosed herein, may use one or more attributes of the set of responses including consistency, complexity, grammar and spelling correctness, and time taken during the responses. The disclosed technique may preprocess the responses, extract features and generate one or more metrics corresponding to the one or more attributes of the one or more responses provided by the subject during a session with the interface. The generated metrics over a baseline session and subsequent sessions may be used to determine trends in the metrics which may be used to estimate the extent of neurotoxicity developed by a subject and may trigger an alert about a potential neurotoxicity or a preventative measure to reduce a likelihood of further neurotoxicity.

TREATMENT PLANNING FOR TUMOR TREATING FIELDS

Resumen de: US20260102612A1

A method for generating a transducer layout for delivering tumor treating fields includes storing medical images of a subject, identifying one of the medical images as an anchor medical image, and registering computed tomography medical images with magnetic resonance imaging medical images. The method further includes segmenting abnormal tissue in the medical images from other tissue types and defining a region of interest (ROI) in the medical images. The method further includes creating a 3D model of the subject. The method further includes generating a plurality of transducer layouts for application of tumor treating fields to the subject, selecting at least two of the transducer layouts as recommended transducer layouts, presenting the recommended transducer layouts, receiving a user selection of at least one recommended transducer layout, and providing a report for the selected recommended transducer layout(s).

NOVEL 3D PRINTING SELF-STABILIZING CERVICAL INTERBODY FUSION CAGE

Resumen de: US20260102258A1

0000 A novel 3D (three-dimensional) printing self-stabilizing cervical interbody fusion cage is provided, including a fusion cage body, circular-arc notches arranged at four corners of a front side surface of the fusion cage body, and threaded openings are formed in interiors of the circular arc notches and screws are correspondingly mounted in the threaded openings. An inner wall of the fusion cage body is of a circular arc structure, and a reserved circular opening is formed in the middle position of the front side surface. Each of the circular arc notches is positioned to form an angle of 45° with a horizontal plane of each of the four corners of the fusion cage body. Screw are self-tapping screws with threads, and the threads of the screws are in fit with threads of the inner walls of the circular arc notches.

DESIGNING PATIENT-SPECIFIC SURGICAL ITEMS

Resumen de: WO2026078555A1

A method of designing a patient-specific surgical item comprising: obtaining, by one or more processors, a 3-dimensional (3D) item model representing at least a surface of a patient-specific surgical item that is shaped to conform to one or more anatomical structures of a patient; determining, by the one or more processors, a size of a 3D primitive shape and a position of the 3D primitive shape such that the 3D primitive shape is collocated with a protrusion artifact of the 3D item model; modifying, by the one or more processors, the 3D item model to exclude portions of the 3D item model collocated with the 3D primitive shape; and generating, by the one or more processors, output data based on the modified 3D item model.

MULTI-FUNCTIONAL POLYMERIZABLE COMPOUNDS AND METHODS OF PRODUCING AND USING THE SAME

Resumen de: WO2026080633A1

The present disclosure provides synthesizing multi-functional polymerizable compounds and methods for the synthesizing the same. The methods include reacting a compound of Formula (Ia) with an epoxide of Formula (Ib) with quantitative conversion, requiring only an aqueous work-up for purification. Further provided herein are methods of producing polymerizable composition, methods of forming an article by additive manufacturing processes (e.g., via 3D printing), such as orthodontic appliances with increased stain resistance.

3D BIOPRINTING PLATFORM FOR GENERATION OF FUNCTIONAL PRIMARY AND HPSC-DERIVED ORGANOIDS IN HYDROGEL CONSTRUCTS

Nº publicación: WO2026080718A1 16/04/2026

Solicitante:

UNIV OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US]

Resumen de: WO2026080718A1

The disclosed concept includes the preparation and use of biocompatible bioinks, as well as techniques and methods therein for bioprinting, preparing and 3D printing primary cells and patient-specific cells and forming functional soft tissue in a three-dimensional construct form that incorporates the cells and mimics native tissues. The biocompatible bioinks include alginate, methylcellulose, and primary or iPSC-derived cells in the form of single cells or aggregates. The bioprinted 3D construct includes one or more of the iPSC organoids, human islets, as well as TEPCs.