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一种3D打印复合材料支架及其制备方法

Resumen de: CN121868005A

本发明提供了一种3D打印复合材料支架及其制备方法，本发明结合3D打印技术、铸造、注塑、渗流法制备3D打印复合材料支架。本发明结合3D打印材料的多孔结构与其他材料，制备出了一种结合力学性能极佳的支架，该方法解决了目前3D打印无法有效直接制备复合材料支架的问题，解决了钛合金、钽合金等3D打印材料多与其他材料结合不牢固的技术问题。该制备方法包括以下步骤：设计多孔结构三维模型，并导出打印机识别格式数据；3D打印得到多孔结构；设计和/或选择其他材料及制备模具；将3D打印得到的多孔结构相对固定于模具中；向模具内灌注其他材料，该材料会流进3D打印多孔结构的孔隙内部；固化和/或硬化得到3D打印复合材料支架。本发明的3D打印复合材料支架可以用于骨科植入物中，该3D打印复合材料支架具备结构牢固、不易破坏，骨长入效果好的优点，可应用于承重部位的大段骨缺损，在起到力学支撑的基础上促进骨组织再生，达到修复大段骨缺损的疗效。

一种3D打印牙冠的陶瓷浆料及其制备方法

Resumen de: CN121872768A

本发明公开了一种3D打印牙冠的陶瓷浆料及其制备方法，包括如下组分：光敏树脂、稀释剂、分散剂、消泡剂、光引发剂、陶瓷粉体；制备的时候包括如下步骤，S1,首先调节混合环境，将混合温度调整30‑40℃；将光敏树脂、光引发剂、稀释剂高速避光搅拌均匀，混合得到光敏树脂体系；S3，将陶瓷粉体、分散剂、助剂加入上述光敏树脂体系中，进行分散得到浆料，在成型软件控制下完成牙科种植体素坯的打印；S8，将素坯进行干燥、脱脂、高温烧结后得到牙冠种植体；本发明所涉及的陶瓷浆料进行3D打印成型的牙冠陶瓷生坯具有很高硬度，而且生坯精度高、打印成功率高。通过脱脂烧结热反应对其内部晶粒尺寸进行重构，经过脱脂烧结后的陶瓷牙冠能够与牙模准确佩戴。

一种骨科导板制作装置

Resumen de: CN224130476U

本实用新型属于骨科技术领域，具体的说是一种骨科导板制作装置，包括机体和保护装置，机体的上表面滑动连接有加工器，机体的上表面滑动连接有垫板，机体的表面固定连接有控制板；机体的表面设有保护装置，保护装置包括支撑板和两个护罩，支撑板的上表面和机体底端固定连接，支撑板的内壁螺纹连接有两个螺纹杆，两个护罩位于机体的表面，垫板的表面设有清理装置，清理装置包括两个放置板，两个放置板的侧壁分别和垫板两侧固定连接，两个放置板的内壁滑动连接有滑架，滑架的底端固定连接有刮刀；通过设置护罩能够对整个设备进行保护，同时减少设备沾染灰尘的情况，而支撑轮能够在一定程度上支撑护罩。

基于多源行为数据的学生心理状态评估与风险预警系统

Resumen de: CN121867791A

0001 本发明公开了基于多源行为数据的学生心理状态评估与风险预警系统，涉及数据处理技术领域。该基于多源行为数据的学生心理状态评估与风险预警系统，包括以下步骤：数据采集与语境绑定模块，用于采集多类行为数据集并进行归一化处理；压力剂量表构建模块，用于构建压力剂量表并生成个体暴露轨迹数据帧；行为响应指纹构建模块，用于构建行为响应指纹数据帧；分级预警决策模块，用于构建风险证据流输出风险轨迹数据帧；闭环校准模块，用于将预警决策编译并构建回执闭环核验数据帧。本发明有效提升了可计算性、可解释性与跨场景泛化稳定性，解决了压力暴露仅以考试周与DDL粗粒度标记，导致模型学习到日历效应而非个体风险的问题。

一种基于多信号分析的吞咽障碍风险预警方法及系统

Resumen de: CN121867704A

本发明提供一种基于多信号分析的吞咽障碍风险预警方法及系统。其中方法包括：通过柔性可穿戴传感单元采集佩戴者颈部的表面肌电信号、生物阻抗信号、喉部振动信号及颈部微环境温湿度信号；利用颈部微环境温湿度信号确定的呼吸相位作为时间基准，对多模态生理信号进行时间对齐与预处理，得到多通道时序数据；对多通道时序数据进行特征提取与融合，生成鉴别性融合特征向量；将向量输入预训练分类模型进行实时推理，识别包括有效吞咽、无效吞咽及可疑误吸在内的吞咽功能状态；响应于识别出的异常状态生成分级风险预警信号。本发明通过多模态信号融合与呼吸节律校准，解决了运动伪影干扰与时序对齐难题，实现了对吞咽障碍风险的精准连续监测。

一种骨质疏松症骨折风险识别系统

Resumen de: CN121867830A

0001 一种骨质疏松症骨折风险识别系统，它涉及一种骨折风险识别系统。本发明为了解决DXA或QCT的检测均不能明确患者发生骨质疏松性骨折的风险高低，检测的准确性不够，也不能有效及时的将骨折高风险患者识别出来的问题。本发明包括CT图像采集模块、数据传输单元和数据处理及显示单元；CT图像采集模块用于采集人体在体腰椎CT图像，并将采集的图像数据通过数据传输单元传输至数据处理及显示单元，数据处理及显示单元根据腰椎椎体皮质骨和松质骨交界的环状区域即皮质骨松质骨的过渡带区域的骨结构参数计算骨折风险水平并输出。本发明属于医疗器械领域。

一种个体化可穿戴经颅磁刺激治疗辅助定位方法

Resumen de: CN121868720A

0001 本发明公开了一种个体化可穿戴经颅磁刺激治疗辅助定位方法，包括步骤：基于T1加权结构成像，通过表面重建得到与个体头部解剖一致的头皮表面、颅骨表面和大脑皮层表面；基于静息态功能磁共振成像，执行全脑功能连接分析得到个体化皮层靶点；在头皮表面识别解剖标志点并构建头皮曲面坐标系，将个体化皮层靶点从大脑皮层表面投射至头皮表面，得到个体化头皮靶点位置；在头皮曲面坐标系中选取耳平面以上的头皮曲面作为头罩基底区域，制作个体化定位头罩的三维模型，并根据个体化头皮靶点位置预留与个体化头皮靶点对应的线圈安放区域；根据三维模型制作个体化定位头罩实体，实现了经颅磁刺激的个体化精确定位、重复放置和标准化操作。

一种基于椭球随机相交分布算法的仿生骨支架设计方法

Resumen de: CN121881435A

0001 本申请公开了一种基于椭球随机相交分布算法的仿生骨支架设计方法，涉及仿生骨支架设计领域，该方法包括：S1.基于Micro‑CT获取目标骨架横断面的CT影像图生成骨松质的微孔结构；S2.分析骨松质的微孔结构确定拟合椭圆的尺寸；S3.基于拟合椭圆的尺寸设置拟合椭圆的中心距，并生成椭圆中心点阵；S4.基于拟合椭圆的长轴旋转拟合椭圆生成椭球单元，并通过随机函数生成当前椭球单元的随机旋转角度；S5.结合循环语句以及椭圆中心点阵，重复椭球单元的复制、偏移和旋转指令，得到由椭球单元组成的圆柱模型，基于圆柱模型生成仿生骨支架。本申请通过椭圆拟合得到有利于细胞的生长、增殖和营养物质传输的仿生骨支架。

幼儿孤独症快速互动筛查测试方法

Resumen de: CN121867784A

0001 本发明属于孤独症筛查技术领域，公开了一种幼儿孤独症快速互动筛查测试方法，适用于18‑36月龄中文环境幼儿。其步骤包括：确定适配测试对象，测试准备，按前3项固定、其余灵活的顺序执行互动测试并评分，将9项得分相加得分，依总分判定风险。该方法5‑10分钟即可完成，适配中文文化、器材简易、操作标准化，解决现有工具适配差、效率低问题；且准确性高、适用社区等多场景，能快速识别孤独症风险，为幼儿孤独症早期干预提供支持。

三维足踝数据处理系统及方法

Resumen de: CN121885063A

0001 本发明公开了一种三维足踝数据处理系统及方法，涉及计算机软件技术领域，该系统中数据计算分析模块包括指标数值模块、指标大数据参考范围模块及指标个人发育随访模块，指标数值模块自动识别三维足部模型中的特征部位点，计算其长度、宽度、高度、角度、面积、体积及截面围度的数据，输出基础指标与特征指标，指标大数据参考范围模块基于三维足部模型数据，统计分析各指标分年龄、分性别的百分位数参考范围，用于个体检测结果的客观比对与评估，指标个人发育随访模块基于用户唯一身份识别码，生成各指标随时间变化的随访曲线，实现长期动态监测与干预效果评估，解决了个体评估缺乏客观量化标准的问题。

一种可穿戴式肘关节角度采集装置及肘关节角度预测方法

Resumen de: CN121867762A

本发明涉及一种可穿戴式肘关节角度采集装置及肘关节角度预测方法，所述肘关节角度采集装置，集成了肌电信号与肘关节角度的同步采集功能，操作简单，同步性强，并具有可穿戴和固定两种模式，适用范围广；本发明提出的肘关节角度预测方法，在数据采集后对肌电信号进行带通滤波、工频干扰抑制及归一化处理，并提取了时域、频域及时频特征，提高了模型对角度变化趋势的敏感性和预测精度；采用回归模型综合肌电信号与肘关节角度，能够实现对肘关节运动角度的实时预测，从而对患者运动意图进行解码，为个性化康复训练提供依据。

歯科矯正用透明アライナー及びアタッチメントの設計方法

Resumen de: KR102686174B1

The design method of transparent orthodontic device and attachment for orthodontic treatment according to the present invention is devised to solve the above technical problem. The method of designing an orthodontic device using a computer comprises the following steps of: designing a shape of an attachment attached to a surface of a tooth model (S01); designing an inner shape of a transparent orthodontic device according to the shape of the attachment designed in step S01 (S02); and printing a transparent orthodontic device using a 3D printer (S03). The attachment comprises: two pressure surfaces (101) formed to face each other; two inclined surfaces (201) formed to face each other and inclined while contacting the two pressure surfaces (101); a top surface (301) where the two pressure surfaces (101) and the two inclined surfaces (201) and their edges all contact each other; and an attachment surface (401) that is attached to the surface of the teeth.

牙科修复体及基于3D打印制备牙科修复体的方法

Resumen de: CN121872675A

本发明提供了一种用于3D打印的牙科修复体材料、牙科修复体及制备方法。该牙科修复体材料以质量分数计包括以下修复体原料：1，6‑己二醇二丙烯酸酯8％～16％，乙氧基化三羟甲基丙烷三丙烯酸酯1％～5％，聚乙二醇4009％～13％，二苯基(2，4，6‑三甲基苯甲酰基)氧化膦0.2％～1％，分散剂1％～5％，玻璃粉60％～85％。其中，玻璃粉的组成以质量分数计包括：SiO2 50％～80％，Li2O 10％～20％，K2O 0.5％～10％，Al2O3 0.5％～15％，成核剂0.2％～10％。所述成核剂为P2O5和/或TiO2。该牙科修复体材料制备的牙科修复体力学强度能超过200MPa。

复层结构颅骨修复支架及其制备方法和制备工艺优化方法

Resumen de: CN121868006A

本申请提供了复层结构颅骨修复支架及其制备方法和制备工艺优化方法，涉及颅骨修复支架技术领域，包括进行CT和核磁共振扫描获得缺损颅骨组织三维结构模型；构建复层结构颅骨修复支架结构基准模型，包括外部金属支撑层、内部生物陶瓷降解再生层和中间过渡界面层；拓扑优化结合挤出模拟、打印模拟和烧结模拟进行联合优化；采用挤出3D打印技术配置3D打印浆料进行打印获得复层结构颅骨修复支架打印体；真空干燥、真空烧结、冷却后获得复层结构颅骨修复支架。本申请结合金属、陶瓷两种材料，外层金属框架提供手术所需初始强度、刚性及可靠的固定能力；内层多孔的可降解生物陶瓷，创造利于新骨生成的微环境，最终实现支架的生物降解与骨组织的原位再生。

一种义肢接受腔、义肢及其制造方法

Resumen de: CN121868011A

本申请提供一种义肢接受腔、义肢及其制造方法，包括：外壳，外壳用于连接义肢体；缓冲层结构，缓冲层结构环绕设置在外壳内，缓冲层结构具有负泊松比特性；柔性内衬，柔性内衬设置在缓冲层结构的内腔内，并形成一侧敞开的接受空腔，接受空腔用于连接用户的残肢；外壳、缓冲层结构以及柔性内衬通过双头3D打印生成，其中在双头3D打印过程中通过第一挤出头和第二挤出头进行同步打印，第一挤出头以柔性材料打印出柔性内衬以及缓冲层结构，第二挤出头以硬质材料打印外壳。解决了现有技术中的义肢接受腔生产工序多、浪费劳动力资源的问题。

METAL OXIDE BIOLOGICAL IONOMER AND METHODS

Resumen de: US20260102509A1

A nanoparticle compound comprising buckminsterfullerene C60 bonded to ester functional groups of pyruvic, citric, and hyaluronic acids, with oxygen-bridged components selected from vanadium, gallium, and bismuth is provided. At least one component enables quantum-mechanical spin-wave activation. Ultrasonic irradiation activates the compound, inducing electrical induction for tissue healing and cell growth. The compound integrates with native and 3D-printed tissues, enhancing their properties through interpenetrating networks. It exhibits anti-inflammatory, antioxidant, and antibacterial effects, reinforces connective tissue, and modulates stem cell growth. The compound treats arthritis, enhances gut health and barrier function, supports bone health, improves voice quality, counters cancer cell proliferation, and mitigates osteoporosis. The gallium component creates an alkaline environment for calcium deposition, while vanadium enhances chondrogenic differentiation. Administration methods include topical application, oral ingestion, injection, and infusion through bandages or sutures. The compound serves as an adjuvant for analgesics, enhancing their delivery and efficacy.

3D SCANNING METHOD, SYSTEM AND APPARATUS FOR DENTAL APPLICATIONS

Resumen de: US20260102230A1

A method and device for aligning face scans with intraoral scans in dentistry applications. Digital intraoral scans capture the upper and lower arches and a bite registration. An Anterior Extension Device is affixed in the patient's mouth. A working scan of the upper arch scan is trimmed to remove the areas covered by the Anterior Extension Device. A rigid reference link extends between the Anterior Extension Device and base of the patient's nose. The working scan is rescanned to include the Anterior Extension Device and rigid reference link and patient's nose. A facial scan is taken while the patient is smiling. The rescanned working scan is aligned and merged with the facial scan on the basis of at least three points of reference on the patient's nose. A prosthetic device is designed using in combination the intraoral scans aligned with the facial scan.

APPARATUS AND METHOD OF DETERMINING A CARDIAC IMPLANT SIZE AND METHODS AND SYSTEMS FOR TRANSESOPHAGEAL ECHOCARDIOGRAM GUIDED IMPLANTATION OF LEFT ATRIAL APPENDAGE CLOSURE DEVICE

Resumen de: WO2026080652A2

Apparatus and methods of determining a cardiac implant size and methods and system for transesophageal echocardiogram guided implantation of left atrial appendage closure device. The apparatus includes an ultrasonic imaging device, at least a processor, and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to using the ultrasonic imaging device collect a plurality of ultrasonic images using a 3D cardiac model generation machine learning model trained on a training dataset including example ultrasonic images correlated with example 3D cardiac models. The processor is further configured to generate a 3D cardiac model based on the plurality of ultrasonic images, generate at least a cardiac measurement based on the 3D cardiac model, determine a cardiac implant size based on the at least a cardiac measurement, and using a display, display to a user the cardiac implant size.

SYSTEM AND METHODS FOR LOCATING DRIVERS OF ATRIAL FIBRILLATION

Resumen de: US20260102102A1

The present disclosure applies to methods of cardiac ablation that use an algorithm to determine where in the heart a driver of atrial fibrillation is located. Catheters with multi-electrode arrays are used to measure electrograms from cardiac signals wherein abnormal signals are identified as electrogram deflections with characteristic shapes. The electrogram deflections are compared to each other in pairs to determine which came first in time in order to determine the net direction of propagation of a fibrillatory wave. The signal that came first is assigned a positive point value so that once the plurality of electrograms have been compared, the signal with the highest point value can be identified as a driver of fibrillation. The data can be displayed graphically as a map of atrial fibrillation drivers on a 3D representation of a heart, allowing surgeons to quickly and easily identify where on the heart the driver is.

HEALTH CONDITION TREATMENT VIA ADAPTIVE LOOP STIMULATION PATCH

Resumen de: WO2026080696A1

A system for real-time management of a health condition in a patient. The system includes a wearable sensor including at least one sensor for measuring physiological responses, electrodes configured to stimulate and record a nerve, and a sensor processing module for receiving the physiological responses and the nerve response and transmitting them to a computing device, as well as actuate the electrodes to stimulate the nerve. The system further includes the computing device configured to actuate the sensor device to deliver an initial stimulation, receive the physiological responses and the nerve response, generate a response profile specific to the patient, actuate the sensor device to deliver subsequent stimulations according to the response profile, receive subsequent physiological responses and a subsequent nerve response, and adjust, based on a change, the response profile. The steps of subsequent stimulation, receiving responses, and adjusting the response profile may be repeated until a target point.

METHOD FOR CALIBRATING AND VERIFYING IMPLANTABLE DETECTING DEVICE, IMPLANTABLE DETECTING DEVICE, APPARATUS, AND ELECTRONIC DEVICE

Resumen de: US20260102090A1

0000 A method for calibrating and/or verifying an implantable detecting device, an implantable detecting device, an apparatus, and an electronic device are provided. The method includes: outputting a square wave signal to an implantable detecting device that has been implanted into a subject, where the implantable detecting device is configured to detect a concentration of an analyte in the subject, and a potential of the square wave signal increases incrementally over time; receiving a first current signal produced by the implantable detecting device in response to the square wave signal; generating a calibration curve based on a correspondence between the first current signal and the square wave signal; and performing calibration and/or functional verification on the implantable detecting device based on the calibration curve.

INJECTION MONITORING MODULE

Resumen de: WO2026078408A1

An injection monitoring module comprises an indicator of rotational movement about a lengthwise axis; a sensor configured to contactlessly detect rotational movement of the indicator about the lengthwise axis; a processor connected to the sensor, wherein the processor is configured to receive and process signals from the sensor; wherein, in a first axial position of the injection monitoring module, the indicator of rotational movement is prevented from rotational movement about the lengthwise axis; and wherein, in a second axial position of the injection monitoring module, distinct from the first axial position, the indicator is free to corotate about the lengthwise axis along with a dose dispensing component of an injection pen system, onto which, or into which, the injection monitoring module has been mounted.

SYSTEMS, METHODS, AND DEVICES FOR TARGET CONTROLLED INFUSION

Resumen de: US20260102564A1

0000 A system for programming infusion devices for target controlled infusion is disclosed. The system includes a docking station and one or more processors configured to determine a first infusion device docked with a docking station and accept user input of one or more of patient-specific parameters, drug-related parameters, and a desired target concentration of a therapeutic agent in a workflow on the first infusion device for programming a target controlled infusion (TCI) therapy. After receiving a particular set of parameters, the set of parameters can be copied to the second infusion device to pre-complete and bypass a number of workflow steps of a second workflow of another infusion device. When the second workflow is accessed, the number of workflow steps of the second graphical interface workflow are pre-completed and bypassed.

Systems and Methods for Determining the Orientation of Motion-Sensing Devices During Physical Activity

Resumen de: US20260102656A1

0000 A computer-implemented method for providing real-time performance feedback includes receiving uncalibrated time-series motion data generated by one or more motion sensors coupled directly or indirectly to an athlete while performing a downhill snow sport, the motion sensor(s) having an unknown rotational orientation relative to the athlete; determining an estimated rotational offset of the motion sensor(s) relative to a body-segment coordinate frame of the athlete, the rotational offset determined using a calibration model; transforming, by the one or more processors, the uncalibrated time-series motion data to calibrated time-series motion data according to the estimated rotational offset, the calibrated time-series motion data aligned with the body-segment coordinate frame; and processing the calibrated time-series data, with the one or more processors, to determine one or more metrics for the athlete.

HYDROGEL-LIKE BIOMIMETIC MATERIAL COMPRISING REGIONALLY DISTRIBUTED MICROENVIRONMENTS, METHOD OF MANUFACTURE, AND USES THEREOF IN RESEARCH, INDUSTRIAL, AND THERAPEUTIC APPLICATIONS

Nº publicación: WO2026078632A1 16/04/2026

Solicitante:

BAC3GEL LDA [PT]
BAC3GEL LDA

Resumen de: WO2026078632A1

Hydrogel-like biomimetic material comprising regionally distributed microenvironments, method of manufacture, and uses thereof in research, industrial, and therapeutic applications The hydrogel-like biomimetic material (100) has a three-dimensional distribution of biomimetic microenvironments (110), wherein each biomimetic microenvironment (110) comprises (a) a polymeric network (A) that simultaneously provides structural support and functional activity; and (b) a water-based suspension (B), wherein the water-based suspension (B) is sustained by the polymeric network (A).