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205
resultados
Última actualización
03/06/2025 [07:14:00]
Resultados 125 a 150 de 205
Resumen de: US2025152307A1
Systems, methods, and devices for producing appliances for expansion of the palate of a patient are provided. A palate expanding orthodontic appliance comprises a teeth engagement portion comprising a plurality of teeth engagement structures and a force generating portion coupled to the teeth engagement portion and configured to apply force to cause the patient's palate to expand. The orthodontic appliances can be designed according to the specifications provided herein and manufactured using direct fabrication methods.
Resumen de: US2025152319A1
An oral appliance is provided for delivering a medicament to at least a portion of teeth and/or soft tissue areas inside a mouth. The oral appliance contains an interior surface having a medicament disposed in or on at least a portion of and/or the entire interior surface of the oral appliance. The interior surface of the oral cavity is formed to fit contours of at least the portion of the teeth and/or soft tissue areas inside the oral cavity and is configured for holding the medicament in contact with at least the portion of the teeth and/or soft tissue areas inside the oral cavity to deliver the medicament to strategic areas in need of treatment. In some embodiments, computer, network and computer readable storage media are provided.
Resumen de: US2025152310A1
A dental appliance may include a first plurality of tooth receiving cavities for anterior teeth and a first plurality of attachment receiving cavities shaped to impart a first plurality of forces and a first counter moment to the anterior teeth, the first plurality of forces being to direct at least one tooth in a posterior direction. The dental appliance may include a second plurality of tooth receiving cavities for posterior teeth and a second plurality of attachment receiving cavities to impart a second plurality of forces and a second counter moment the posterior teeth, the second counter moment being in a direction opposing the first counter moment. At least a portion of the second plurality of forces may be configured to oppose the first plurality of forces. The first counter moment and the second counter moment may be configured to be coupled to form a differential moment.
Resumen de: US2025152121A1
A formulation usable as a modeling material formulation in additive manufacturing of a three-dimensional object and additive manufacturing methods utilizing same are provided. The formulation comprises one or more curable materials; and a radiopaque material, and features, when hardened, a CT number of at least 100 HU at 70 kV. Objects made by the additive manufacturing method utilizing the formulation are usable as radiological phantoms.
Resumen de: US2025157621A1
A system and method for automatically generating orthodontic appliance prescriptions and designs, which utilizes a cloud-based platform integrated with technologies such as machine learning, natural language processing, and 3D printing. The system operates by receiving Standard Tessellation Language (STL) files from user devices, analyzing these files using STL logic, and comparing them against a comprehensive database of stored STL files. Orthodontic appliance prescriptions are generated incorporating user input and utilizing natural language processing to interpret textual data. Upon selection of a prescription, graphical 3D logic generates a visual representation of the appliance, which is then translated into a 3D-printable STL file optimized for medical-grade materials. The platform may employ feedback mechanisms and AI-enabled features for additional functionalities, such as billing, case tracking, and customer support, while ensuring compliance with healthcare regulations and quality assurance protocols for the production of orthodontic appliances.
Resumen de: US2025156661A1
A system is described to create customized unique identification (UID) codes combined with customized printable optical or NFC sensors and to combine these unique sensors and unique IDs with unique environmental events, traceability, unique data from cell phones (including geolocation) and person-specific unique indicators such as biomarkers to create completely unique, low cost and proprietary printable genomic and environmental blockchain sensor networks for the Internet of Things (IoT), counterfeit identification, healthcare, pharmaceutical applications and small payment transactions worldwide.
Resumen de: WO2025099555A1
The invention relates to an alloplastic prosthesis (20) for the complete or partial reconstruction of the outer ear (22) of a patient (24). The alloplastic prosthesis comprises a plurality of shaped layers (26) stacked and joined to each other, wherein some layers are made of thermoplastic polyurethane (TPU) and other layers are made of polycaprolactone (PCL); at least the outer surface of the alloplastic prosthesis comprises a plurality of pores (28) having a predefined structure and surface comprised between 0.1 mm2 and 0.2 mm2. The invention further relates to a method (100) for manufacturing the alloplastic prosthesis.
Resumen de: DE102023131266A1
Die Erfindung betrifft ein strahlungshärtende Zusammensetzung für die Herstellung dentaler Bauteile in einem 3D-Druck-Verfahren, umfassend bezogen auf die Gesamtmasse der strahlungshärtenden Zusammensetzung: i) ein oder mehrere radikalisch polymerisierbare Monomere in einem kombinierten Massenanteil von 30 % oder mehr, ii) einen oder mehrere erste Füllstoffe in einem kombinierten Massenanteil von 5 % oder mehr, wobei der oder die ersten Füllstoffe einen mittleren Partikeldurchmesser D50 von 150 nm oder weniger aufweisen, iii) einen oder mehrere vom ersten Füllstoff verschiedene zweite Füllstoffe in einem kombinierten Massenanteil von 5 % oder mehr, wobei der oder die zweiten Füllstoffe ausgewählt sind aus der Gruppe bestehend aus Feldspaten, und iv) einen oder mehrere Photoinitiatoren mit einem kombinierten Massenanteil im Bereich von 0,001 bis 10 %, wobei der kombinierte Massenanteil an Füllstoffen 30 % oder mehr beträgt.
Resumen de: AU2025202950A1
The present disclosure provides a surgical implant device, including: a solid surface; and a lattice structure disposed adjacent to the solid surface, wherein the lattice structure includes a first plurality of struts that define a first plurality of voids adjacent to the solid surface and a second plurality of struts that define a second plurality of voids remote from the solid surface. The surgical implant device may also include one or more screw hole regions and/or a needle-populated porous surface disposed adjacent to the solid surface opposite the lattice structure. Fig 1 10,16 12 14b 14c14
Resumen de: KR102807975B1
본 발명은 착용자의 두상에 맞게 헬멧의 외피와 내피를 교체할 수 있도록 설계된 헬멧으로,헬멧의 경질 외피와 체결 구조를 통해 착용 중 안정성을 유지하면서도 두상 교정이 가능하도록 고안된 3D 프린팅 기반의 장치에 관한 것으로, 착용자의 머리 전단을 덮고 안착되는 3D 프린팅을 이용하여 제작되는 경질의 제1 외피부; 상기 제1 외피부의 후단에 맞물려 체결되며, 착용자의 머리 후단을 덮고 안착되는 3D 프린팅을 이용하여 제작되는 경질의 제2 외피부; 상기 제1 외피부와 상기 제2 외피부의 각 측면 사이에 설치되어 상기 제1 외피부와 상기 제2 외피부를 상호 체결하는 외피 체결부; 착용자의 두상 교정을 위해 상기 제1 외피부의 내향면에 설치되는 연질의 제1 내피부; 착용자의 두상 교정을 위해 상기 제2 외피부의 내향면에 탈부착 가능하도록 설치되는 연질의 제2 내피부; 및 착용자의 두상이 커짐에 따라 보다 작은 두께로 교체 가능하도록 상기 제2 외피부와 상기 제2 내피부 사이에 설치되는 다양한 두께로 구비되는 중간부;를 포함한다.
Resumen de: EP4552608A1
This invention provides a more efficient, cost-effective, and streamlined method for manufacturing transparent orthodontic devices by utilizing 3D printing technology. It simplifies the production process, reduces collaboration time, and ensures that the aligners are customized for the patient's specific orthodontic needs.
Resumen de: EP4553104A1
An object of the invention is a method for obtaining a homogeneous collagen suspension, characterized in that it comprises the following stepsI. to collagen, with mixing, preferably on a vortex, a solution composed of a mild organic solvent and a buffer, with the addition of acids is added wherein:- as the collagen preferably type I collagen is used, preferably it is the collagen derived from bovine tendons,- the concentration of the collagen with respect to the solvent is in the range of 0.1 to 15% w/v,- the organic solvent is a solvent exhibiting low surface tension relative to the collagen, preferably the solvent is a solvent for which the contact angle value for collagen is below 20°, most preferably the organic solvent is dimethyl sulfoxide (DMSO),- the buffer is a buffer containing salts naturally occurring in a living organism, preferably the buffer is a phosphate buffer (PBS),- the solvent and the buffer can be mixed together in various proportions, preferably the solvent and the buffer are mixed in a ratio of 5 parts of the solvent to 1 part of the buffer, by volume, most preferably 5 parts DMSO to 1 part PBS, by volume,- the acids are HCl and HF, wherein the concentration of each of the acid in the solution is not higher than 0.1 M,II. subsequently, the solution obtained in step I. is mixed at a temperature of 2 - 8°C, preferably 4 - 6°C, for a period of 3 to 7 days, preferably for a period of 3 days,III. subsequently, the solution obtained in step II., while mix
Resumen de: US2024016579A1
Disclosed herein are dental attachment placement devices generated from curable compositions by additive manufacturing. The curable compositions contain a high crosslinker content, and after curing, yield tough and color neutral materials suitable for dental attachment placement devices.
Resumen de: AU2023303676A1
Element (100, 200, 300) for augment or bone filler, comprising at least one first outer-layer portion (101) having a trabecular lattice of metallic material, and further comprising at least one reinforcing inner layer (103) of metallic material having a plurality of channel structures (104) arrayed with respective channel openings (105) delimited by edges in structural contact with the at least one first outer-layer portion (101).
Resumen de: US2024016578A1
Disclosed herein are methods for manufacturing medical devices, such as implants, joint replacements, graft materials, augmentation materials, prosthetic materials, etc., from solid material reinforced curable resins. Methods of repositioning a patient's teeth using such medical devices are also provided.
Resumen de: CN119971134A
本发明涉及一种用于细胞3D打印的高强度光敏生物墨水水凝胶及其制备方法，属于生物材料技术领域。该方法直接采用高强度材料NAGA为生物墨水水凝胶提供高强度，通过3D打印载细胞生物活性墨水，实现生物活性和高强度的兼顾。并在绿光下进行交联以避免光照对细胞的损伤，通过在生物墨水中抗氧化剂以避免光引发剂产生的自由基对细胞的攻击，最终实现用于细胞3D打印的高强度光敏生物墨水水凝胶制备。本发明制备得到的生物墨水水凝胶，可以实现高的力学性能和生物(细胞)活性的兼顾，有效的避免紫外光对于细胞的损伤，解决了长时间光照下光引发剂产生的自由基对细胞的损伤的问题。
Resumen de: CN119977543A
本发明提供了一种生物陶瓷支架及其制备方法和应用，属于组织修复材料技术领域。本发明通过DLP光固化3D打印技术，将具有与人体骨相近的抗压强度以及适中的降解速率的镁黄长石，设计出了一种用于提升骨组织修复的生物陶瓷支架，且机械强度和孔隙率及支架结构满足骨修复支架要求。本发明利用DLP光固化3D打印技术制备了一种新型多孔生物陶瓷支架，探索了支架形态、固含量、烧结参数对骨修复支架机械性能的影响，最终制备得到机械性能高的骨修复效果优异的生物陶瓷支架。
Resumen de: AU2023345391A1
There is provided a hydrogel string for encapsulating a biological material. The hydrogel string has a thiol-ene crosslinked polymer with a first side-chain functionalized backbone polymer functionalized with an activated alkene crosslinked with a free or protected thiol-containing group present on a second side-chain functionalized backbone polymer. The biological material is encapsulated within the thiol-ene crosslinked polymer.
Resumen de: US2024408834A1
One embodiment of an ocular lens includes a lens body configured to contact an eye where the lens body has an optic zone shaped to direct central light towards a central focal point of a central region of a retina of the eye. At least one optic feature of the lens body has a characteristic that directs peripheral light off axis into the eye away from the central region of the retina. Another embodiment of an ocular lens has at least one isolated feature of the lens body that has a characteristic of directing peripheral light off axis into the eye away from the central region of the retina. Methods of making contact lenses include forming the features during the manufacturing process.
Resumen de: CN119971138A
本发明适用于口腔种植学技术领域，提供了用于简化口腔骨增量手术4D打印支架的制备方法及应用。本发明利用4D打印技术，将聚多巴胺和海藻酸钠混合打印成水凝胶支架，经锶离子交联后，该支架展现出优异的生物可降解性和生物相容性，可替代钛网弯曲支架，有效维持成骨空间，并降低种植骨增量手术的高技术敏感度。该支架能精准适配不同骨缺损轮廓，提供支撑并加速愈合，降低并发症风险。其适配性强、植入简便，能最大程度减少不必要的组织剥离与损伤，缩短手术时长，利于患者术后恢复。在水平骨增量手术中，该支架能为后续牙种植等修复手段提供坚实的骨基础。形变产生的机械信号与支架释放的生物活性成分协同作用，加快骨组织再生。
Resumen de: CN119971139A
本发明属于生物医学领域，具体涉及一种3D生物打印的促血管化膀胱补片及其制备方法。本发明将所制备的GelMA与Laponite聚合，制备出GelMA‑Laponite水凝胶，然后利用3D生物打印机器在膀胱脱细胞基质上将GelMA‑Laponite水凝胶和种子细胞混合打印为具有三维空间结构的GelMA‑Laponite支架，支架使用紫外光交联，得到双层血管化膀胱补片。本发明有望提升组织工程化膀胱补片的构建水平，解决组织工程膀胱移植物的血管化问题，为推动膀胱组织工程的临床应用进程奠定了良好的理论基础与技术支撑。
Resumen de: CN115740495A
The invention relates to a method for 3D printing of a bone trabecula oral implant. The bone trabecula oral implant comprises an implant base body and a bone trabecula porous structure which are integrally formed. The bone trabecula porous structure is positioned in the axial middle section of the implant base body; and the implant base body is provided with an external thread. The printing method comprises the following steps: obtaining an oral implant 3D model with a bone trabecula porous structure through three-dimensional design software; carrying out molding manufacturing, sand blasting and annealing treatment by utilizing an SLM technology to obtain a bone trabecula oral implant primary product; and forming a tantalum metal coating on the surface of the primary product of the bone trabecula oral implant by using a vapor deposition technology to obtain the bone trabecula oral implant with the tantalum coating. The bone trabecula oral implant obtained by the method is high in density and mechanical strength, favorable for the implant to exert a good repairing effect, and excellent in application prospect.
Resumen de: CN119977560A
本发明公开了一种使用3DFP增材制造的具有梯度结构的生物陶瓷骨支架制备方法；包括：设计生物梯度结构模型；配备包含纳米氧化锆、磷酸三钙、羟基磷灰石和氧化银粉末的丝材原料，混合制浆，制备丝材；将制备的丝材加入打印机中，按切片路径完成梯度结构的逐层打印，获得支架坯体；热处理，之后随炉冷却至室温，即得所述生物陶瓷骨支架。本发明通过深层次优化丝材原料的组成配比，提升支架材料的机械强度；与此同时通过成分梯度和结构梯度双重设计，在保证密质骨高强度、硬度、抗弯性的基础上内层设计成分与结构不同的松质骨，借此来保证支架与组织或细胞有效地相互作用，促进骨细胞的黏附、增殖和分化，有助于组织修复和再生。
Resumen de: EP4553104A1
An object of the invention is a method for obtaining a homogeneous collagen suspension, characterized in that it comprises the following stepsI. to collagen, with mixing, preferably on a vortex, a solution composed of a mild organic solvent and a buffer, with the addition of acids is added wherein:- as the collagen preferably type I collagen is used, preferably it is the collagen derived from bovine tendons,- the concentration of the collagen with respect to the solvent is in the range of 0.1 to 15% w/v,- the organic solvent is a solvent exhibiting low surface tension relative to the collagen, preferably the solvent is a solvent for which the contact angle value for collagen is below 20°, most preferably the organic solvent is dimethyl sulfoxide (DMSO),- the buffer is a buffer containing salts naturally occurring in a living organism, preferably the buffer is a phosphate buffer (PBS),- the solvent and the buffer can be mixed together in various proportions, preferably the solvent and the buffer are mixed in a ratio of 5 parts of the solvent to 1 part of the buffer, by volume, most preferably 5 parts DMSO to 1 part PBS, by volume,- the acids are HCl and HF, wherein the concentration of each of the acid in the solution is not higher than 0.1 M,II. subsequently, the solution obtained in step I. is mixed at a temperature of 2 - 8°C, preferably 4 - 6°C, for a period of 3 to 7 days, preferably for a period of 3 days,III. subsequently, the solution obtained in step II., while mix
Nº publicación: KR20250065080A 12/05/2025
Solicitante:
사회복지법인삼성생명공익재단
Resumen de: WO2025095385A1
The present invention relates to a porous three-dimensional meniscus scaffold and a biodegradable medical device comprising same. According to the present invention, external force applied to the meniscus scaffold can be more reliably and evenly dispersed by appropriately adjusting a ratio of intervals between fibers inside the meniscus scaffold, and thus the biodegradable medical device comprising the meniscus scaffold has greater structural stability.
BOPI
Sede Electrónica
