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一种基于4D打印的膝关节矫形支具制备及驱动方法、支具结构

Resumen de: CN120297073A

本发明涉及一种基于4D打印的膝关节矫形支具制备及驱动方法、支具结构，其中制备方法及驱动方法通过结合膝关节三维扫描体表数据和医学影像，建立具有膝关节畸形特征的生物力学模型，为打印支具提供模型基础，为驱动支具提供预测参数，提高支具实用性；其中支具结构包括第一矫形板和第二矫形板，并通过第一连板和第二连板连接，便于组装且穿戴后不影响行走；驱动方法包括利用具有膝关节畸形特征的生物力学模型，进而结合深度学习算法构建膝关节矫形目标角度预测模型，为矫形支具的各次形态改变提供参照，且模型可以根据具体阶段调整继续使用，提高效率，提高资源利用率。

一种用于光固化3D打印的氧化锆膏料及其制备方法

Resumen de: CN120289180A

本发明公开了一种用于光固化3D打印的氧化锆膏料及其制备方法，其原料按重量份包括：氧化锆掺杂物：72％‑76％；光敏树脂预混液：12％‑14％；流变助剂：1％‑2％；分散剂：0.8％‑1.5％；消泡剂：0.05％‑0.1％；流平剂：0.05％‑0.1％；溶剂：10％‑12％；着色剂：0.3％‑0.6％；本发明涉及增材制造技术领域。该用于光固化3D打印的氧化锆膏料及其制备方法，通过三级级配的氧化锆掺杂物作为主体材料，在光敏树脂预混液、流变助剂、分散剂、消泡剂、流平剂和溶剂的配合下，确保各成分充分分散，为氧化锆膏料在3D打印成型过程中提供均匀稳定的保障，有效消除成品的表面和内部缺陷，并且利用着色剂模拟天然牙色，既具备良好的加工性能又拥有良好的力学性能、生物相容性以及美学效果。

一种基于3D打印的个性化口咽通气道装置

Resumen de: CN120284580A

本发明涉及医疗器械技术领域，特别涉及一种基于3D打印的个性化口咽通气道装置。本发明的基于3D打印的个性化口咽通气道装置包括3D打印的咽通气道主体，所述咽通气道主体一端设有限位部，所述咽通气道主体的内壁上设有气流感应器，所述限位部上设有处理器、电源和通讯器，所述处理器分别连接所述电源、气流感应器和通讯器，所述电源连接所述通讯器。优点：结构设计简单、合理，装置根据患者的口咽形状个性化定制，佩戴更加舒适，同时，能够在OSA患者睡眠时，辅助打开气道，避免口腔内软组织堵塞气道，同时，能够实时监测气道的通畅情况，记录相关数据，帮助患者及医护人员了解睡眠呼吸状况，以便及时进行调整及救治。

BIOMATERIAL FOR USE IN THE DENTAL FIELD

Resumen de: AU2023410422A1

The present invention relates to a crosslinkable polymer composition comprising at least one calcium phosphate, at least one biocompatible and biodegradable organic polymer or one of its precursors, and Zn-ZnO core-shell particles, to a biomaterial obtainable by photopolymerization of such a crosslinkable polymer composition, to a process for preparing such a composition and such a biomaterial, and to the use of such a biomaterial for various applications in the field of health.

マイクロポストアレイ装置及び生体適合性足場構築物

Resumen de: CA3203310A1

A biocompatible scaffold construct may include a biocompatible hydrogel and at least one biomaterial microfiber strand wound to form a plurality of microfiber segments in proximity to one another and arranged in an organized configuration.

３Ｄプリンターを使用した透明矯正装置の製造方法

Resumen de: CN119403514A

The invention discloses a method for manufacturing a transparent correction device based on a 3D printer, namely a method for executing the transparent correction device through a computer, and the method comprises the following steps: (A) scanning an oral cavity structure of a patient, and generating and storing data related to the shape of the oral cavity structure; (B) displaying the oral cavity structure of the patient on the basis of the data stored in the step (A); (C) setting detailed correction information on the oral cavity structure of the patient displayed in the step (B), the step (C) comprising: selecting a tooth to be corrected in a state where the oral cavity structure of the patient is displayed, and inputting correction values of the rotation amount and the movement amount of the selected tooth; a step for inputting the scale of the transparent correction device on the basis of the input correction value; and a step of inputting the thicknesses of the portion where the transparent orthodontic device is in contact with the orthodontic teeth and the portion where the transparent orthodontic device is not in contact with the orthodontic teeth, respectively, so that the thicknesses of the transparent orthodontic device are partially differentiated.

GRAFT SCAFFOLD FOR CARTILAGE REPAIR AND PROCESS FOR MAKING SAME

Resumen de: US2025222166A1

The present invention relates to a method of providing a graft scaffold for cartilage repair, particularly in a human patient. The method of the invention comprising the steps of providing particles and/or fibres; providing an aqueous solution of a gelling polysaccharide; providing mammalian cells; mixing said particles and/or fibres, said aqueous solution of a gelling polysaccharide and said mammalian cells to obtain a printing mix; and depositing said printing mix in a three-dimensional form. The invention further relates to graft scaffolds and grafts obtained by the method of the invention.

A DEVICE FOR SKIN BIOPRINTING AND A METHOD OF MAKING A DEVICE FOR SKIN BIOPRINTING

Resumen de: US2025221814A1

There is provided a device for skin bioprinting and a method of making a device for skin bioprinting, the device comprising: a dispenser module configured to actuate and dispense a bioink from a first chamber, and to actuate and dispense a crosslinker from a second chamber: a storage module coupled to the dispenser module, the storage module comprising the first chamber for storing the bioink and the second chamber for storing the crosslinker; a mixing module coupled to the storage module for mixing the bioink and the crosslinker dispensed from the first and second chambers respectively; and a rotatable applicator coupled to the mixing module for rotatably applying a mixture of the bioink and crosslinker from the mixing module onto a surface of a patient in need of skin regeneration.

TALUS FORMATION AND IMPLANTATION METHOD

Resumen de: US2025221826A1

A process for printing a talus implant comprising the steps of scanning a joint for a damaged talus, and scanning a contralateral joint for a healthy talus. Next, the process includes obtaining dimensions for a talus based upon an initial scan and then obtaining dimensions for a talus based upon the scan of the contralateral joint. Next the process includes inverting the dimensions of the talus in the contralateral joint and then comparing the dimensions of the calculated talus with a pre-set of dimensions in a database. Next the process includes exporting a set of dimensions to a printer to print a talus implant.

METHOD AND SYSTEM FOR FABRICATING OBJECT FEATURING PROPERTIES OF A HARD TISSUE

Resumen de: US2025221824A1

A method of additive manufacturing an object featuring properties of a hard bodily tissue, comprises: dispensing and solidifying a plurality of non-biological material formulations to sequentially form a plurality of hardened layers in a configured pattern corresponding to a shape of the object. The method forms voxel elements containing different material formulations at interlaced locations to provide a three-dimensional textured region spanning over the portion. The material formulations and the interlaced locations are selected such that the textured region exhibits, once hardened, a stress variation of at most ±20% over a strain range of from about 0.1% to about 0.3%.

MECHANICAL ENTRAPMENT STRUCTURES AND METHODS OF COATING ADDITIVELY MANUFACTURED OBJECTS USING THE SAME

Resumen de: US2025221803A1

Provided herein are methods of making a coated object that include applying a coating composition to a surface of an object that comprises a plurality of entrapment structures thereon, wherein the coating composition is on at least a portion of the plurality of entrapment structures; and curing and/or solidifying the coating composition to form the coated object. Also provided are coated objects formed by such methods. Additionally, provided herein are methods of bonding a first surface to a second surface wherein the first surface and/or the second surface comprises a plurality of entrapment structures thereon. Composite articles are also provided herein.

METHOD OF ORGANOID DERIVED PRODUCTION OF HUMAN EXTRACELLULAR MATRIX HYDROGELS

Resumen de: US2025223568A1

Disclosed herein is a method of extracting extracellular matrix (ECM) from organoids via decellularization and hydrogels formed from methods thereof. The hydrogels can be used in medical devices for regenerative medicine like tissue grafts, and research and development applications to enhance disease modeling utilizing 3D bioprinting or other hydrogel embedding processes. The hydrogels can also be used to enhance tissue culture flasks for cells by offering a softer environment than polystyrene for cell culture. The hydrogels can be used in drug and vaccine delivery as well.

METHOD FOR MANUFACTURING TRANSPARENT BLEACHING TRAY

Resumen de: US2025222654A1

The method of manufacturing a transparent whitening tray according to the present invention includes 3D printing of the whitening tray using the composition for forming a transparent whitening tray as a raw material (S10), removing uncured resin and liquid from the whitening tray obtained in the above step (S20), post-curing the whitening tray obtained in the above step (S30), post-heat treating the whitening tray obtained in the above step (S40), and washing the whitening tray obtained in the above step (S40).

METHOD OF FORMING AN ALIGNED TISSUE OR TISSUE CONSTRUCT, A TISSUE OR TISSUE CONSTRUCT, AND BIOINK

Resumen de: US2025222168A1

Described herein is a method of forming an aligned tissue or tissue construct. The method includes extruding a bioink material through a nozzle onto a support to form a structure of the bioink material, the bioink material comprising anisotropic organ building blocks (aOBBs) comprising extracellular matrix material (ECM) and cellularly aligned cells, wherein the aOBBs align parallel to the direction of the extrude path, and polymerizing the structure of the bioink material, thereby forming the tissue or tissue construct having arbitrarily programmed alignment. Also, described is a tissue or tissue construct produced by the method, as well as bioink material used to produce the same.

PHOTOINTIATOR, BIOINK INCLUDING THE SAME, AND METHODE OF MANUFACTURING HYDROGEL

Resumen de: US2025222169A1

The present disclosure relates to a photoinitiator, a bioink including the same, and a method of manufacturing a hydrogel. According to the present disclosure, the photoinitiator of the present disclosure may have water solubility, high molar extinction coefficient, and low cytotoxicity. In addition, the method of manufacturing a hydrogel of the present disclosure may have high cell viability by increasing 3D printing efficiency due to a fast photo-curing rate.

ANTIBACTERIAL BIOMEDICAL IMPLANTS AND ASSOCIATED MATERIALS, APPARATUS, AND METHODS

Resumen de: US2025222178A1

Methods for improving the antibacterial and/or bone-forming characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant may comprise a composite of a silicon nitride ceramic powder dispersed within a poly-ether-ether-ketone (PEEK) or a poly-ether-ketone-ketone (PEKK) substrate material. In some implementations, the biomedical implant may be 3D printed.

INTRAOPERATIVE ANATOMICAL LANDMARK IN THYROID SURGERY - RECURRENT LARYNGEAL NERVE INTERSTITIAL FLUID SHEATH

Resumen de: US2025225892A1

The present disclosure is directed to an artificial 3D scaffold of thyroid comprising artificial laryngeal and tracheal framework, wherein the scaffold comprises an artificial interstitial fluid sheath. Further, methods for obtaining a 3D scaffold according to the present disclosure and methods for identification of the recurrent laryngeal nerve in a subject, are disclosed.

THREE-DIMENSIONAL ANATOMICAL PARTS

Resumen de: US2025225755A1

Anatomical parts including surgical trainers and prosthesis and methods of creating three-dimensional anatomical parts by gathering three-dimensional image data from multiple sources, indexing characteristics from the data and then averaging the data to create new anatomical parts that have averaged characteristics. The disclosed methods also enable bonding of various materials through printed lattices.

METHOD OF MANUFACTURE OF CUSTOM CRANIAL REMODELING DEVICES BY ADDITIVE MANUFACTURING

Resumen de: US2025225753A1

A method for fabricating a custom cranial remodeling device for correction of cranial deformities in a subject is described. The method comprises generating a three-dimensional head data file for the subject and determining contour lines on the head. The method further comprises automatically generating a modified head shape data file. Still further the method includes utilizing the modified head shape data file to generate a shape for a desired custom cranial remodeling device and restricting growth of the head in first areas.

METHOD OF MANUFACTURE OF CUSTOM CRANIAL REMODELING DEVICES BY ADDITIVE MANUFACTURING

Resumen de: US2025225754A1

A method for fabricating a custom cranial remodeling device for correction of cranial deformities in a subject is described. The method comprises generating a three-dimensional head data file for the subject and determining contour lines on the head. The method further comprises automatically generating a modified head shape data file. Still further the method includes utilizing the modified head shape data file to generate a shape for a desired custom cranial remodeling device and restricting growth of the head in first areas.

3D PRINTING COMPOSITIONS FOR STAIN RESISTANT AND MORE TRANSPARENT DENTAL MATERIALS FROM POLYOLEFIN DERIVED POLYOLS

Resumen de: WO2025147626A1

The present disclosure provides novel oligomer compounds (e.g., non-polar oligomers) that can produce desirable polymeric materials (e.g., with polar reactive diluents), polymer compositions, and/or photo-curable resins that have excellent stain resistance. Further provided herein are methods of producing polymerizable compositions, resins, devices, and polymeric materials. Also provided herein are methods of using polymerizable compositions, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances with increased stain resistance.

SURGICAL INSERT AND BONE CEMENT

Resumen de: WO2024047317A1

The present invention relates to a surgical insert (1) comprising a first layer (11) and a second layer (12), wherein the first layer and the second layer comprise openings (111, 112) having a figure-of-eight shape. The invention also relates to a bone cement comprising a pulverulent solid phase that comprises natural polysaccharides and a ceramic filler, a liquid acrylate, and a polymerising agent.

SYNTHETIC BONE GRAFTS AND METHODS FOR THEIR PREPARATION

Resumen de: WO2024047045A1

The present invention provides methods for the preparation of synthetic bone grafts which are made of a composition comprising two matrixes, one ceramic including interlocked CDHA crystals, and another of one or more binder(s), the two matrixes being admixture. The method comprises the preparing of an ink composition, the 3D-printing, and the hardening of the binder and ceramic components, in this order. The resulting bone grafts, which are characterized by including the two matrixes in admixture, shows improved mechanical properties as well as excellent biological properties.

ARTICLES INCLUDING A MICROSTRUCTURED CURVED SURFACE, TOOLING ARTICLES, AND METHODS

Resumen de: WO2024047419A1

The present disclosure provides a microstructured article including a thermoplastic polymer shaped to have a curve. At least a portion of the curve includes a microstructured surface of utilitarian discontinuities and the microstructured surface includes peak structures and adjacent valleys. The peak structures and the curve are formed of a single piece of the thermoplastic polymer. A method of making the microstructured articles is also provided including a) obtaining a tool shaped to include at least one of a protrusion or a concavity; b) disposing a microstructured film on at least a portion of the tool including the protrusion and/or the concavity; and c) thermoforming a single piece of thermoplastic polymer onto the tool to form a microstructured article shaped to include a curve. The curve is an inverse of the protrusion or the concavity of the tool.

変形部材、変形部材の製造方法、マスク、カプセル、カテーテル

Nº publicación: JP2025103477A 09/07/2025

Solicitante:

株式会社コーセー

Resumen de: JP2025103477A

【課題】より簡単に作製することができる変形部材を提供する。【解決手段】変形部材１０は、液体を膨潤させることにより膨潤する膨潤性ゲルからなる板状の変形部材であって、一方の表面に複数の溝１１が並列に延びている。【選択図】図１