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Brain disease diagnosis and brain disease information provision system

Resumen de: KR20260123831A

본 발명에 따른 뇌질환 진단 및 뇌질환 정보 제공 시스템은 뇌 영상을 입력받는 영상 입력부와 영상 입력부로부터 제공된 뇌 영상을 통해 뇌질환을 진단하고 진단파일을 생성하는 뇌질환 진단부와 영상 입력부로부터 제공된 뇌 영상을 통해 뇌 신경로를 추적하고 추적파일을 생성하는 뇌신경로 추적부와 뇌질환 진단부의 진단파일 및 뇌신경로 추적부의 추적파일을 통해 뇌질환 정보 파일을 생성하고, 뇌질환 정보 파일을 통해 뇌질환에 대한 시각적 및 언어적 정보를 제공하는 정보 제공부를 포함하는 것을 특징으로 한다.

不利环境下的医疗设备自适应控制

Resumen de: WO2021041437A1

A medical device is configured to monitor, using one or more sensors, an environmental condition of a physical environment proximate to a medical device, and to determine when a value representative of the environmental condition exceeds a threshold for safe operation of the medical device with regard to care of a patient. Responsive to the value exceeding the threshold, an operation mode of the medical device is automatically switched from a first mode currently programmed for the care of the patient to a second mode, the second mode using different parameters than the first mode to control the medical device.

Procédé servant à marquer automatiquement sur un scanner l’intersection de l’axe d’un implant dentaire avec un élément radio opaque.

Resumen de: FR3171987A1

La présente invention concerne le domaine de l’implantologie dentaire. Elle décrit un procédé permettant de marquer automatiquement sur l’image d’un scanner radiologique dentaire les points d’intersection de l’axe d’un implant avec tout élément radio opaque d’un guide radiologique Ce procédé permet également d’imprimer sur n’importe quel support, à l’échelle un sur un, l’image de tout élément radio opaque d’un guide radiologique avec les points d’intersections. Figure d’abrégé : FIG. 2

PATIENT REQUEST SYSTEM HAVING PATIENT FALLS RISK NOTIFICATION AND CAREGIVER NOTES ACCESS

Resumen de: US20260232282A1

0000 st system includes a tablet computer that configured for entry of patient requests. The tablet computer is configured to display a first menu corresponding to basic request categories for a patient. The tablet computer is configured to display a second menu that corresponds to specific patient requests falling under the basic request category selected by the patient using the first menu. A server is configured to receive a specific patient request made by the patient. A notification device is configured to display the specific patient request to a caregiver. A patient request method is also disclosed.

REAL TIME IMAGE GUIDED PORTABLE ROBOTIC INTERVENTION SYSTEM

Resumen de: US20260232394A1

0000 An image-guided robotic intervention system ("IGRIS") may be used to perform medical procedures on patients. IGRIS provides a real-time view of patient anatomy, as well as an intended target or targets for the procedures, software that allows a user to plan an approach or trajectory path using either the image or the robotic device, software that allows a user to convert a series of 2D images into a 3D volume, and localizes the 3D volume with respect to real-time images during the procedure. IGRIS may include sensors to estimate pose of the imaging device relative to the patient to improve the performance of that software with respect to runtime, robustness, and accuracy.

VASCULAR GRAFT ASSEMBLIES, VASCULAR GRAFT SYSTEMS, AND METHODS OF USE THEREOF

Resumen de: US20260232426A1

Reinforced external graft support assemblies and methods of manufacture and implantation are provided herein. In particular, graft support assemblies are composed of single or multilayer sheaths designed to provide mechanical support to vascular conduits during cardiovascular bypass surgery. Graft sheath systems may be fabricated using 3D printing techniques with biocompatible materials incorporate surgical design considerations such as mechanical strength, flexibility, porosity, and the ability to be tailored to specific anatomical structures. External graft sheaths may include one or more layers of various biomaterials to produce customized biomechanical properties including varied time courses of degradation. Furthermore, these customizable features may incorporate standardized designs or be tailored for individual patients depending on medical and surgical history, or other pertinent geometric attributes measured in pre-operative medical imaging. These methods protect vascular conduits, particularly venous grafts, from adverse remodeling and graft failure, thereby providing precision medicine solutions to cardiovascular bypass surgery.

GENERATION OF ARTIFICIAL INTRA-OPERATIVE SENSOR DATA

Resumen de: US20260232380A1

0000 A computer-implemented method of generating artificial intra-operative sensor data usable in training an artificial intelligence (AI) module is presented. The method comprises the following steps: providing a clinical data structure describing several clinical states of a clinical procedure and defining transitions between said several clinical states allowing for different paths of the clinical procedure (step S1); providing at least one geometrical model for modelling procedural scenes in one or more of said clinical states of said clinical procedure (step S2), wherein the at least one geometrical model comprises a plurality of geometrical model parameters and boundary conditions for said geometrical model parameters; wherein the geometrical model parameters describe said procedural scenes in said clinical states of said clinical procedure, wherein a particular combination of values of the geometrical model parameters defines a particular procedural scene of a clinical state of said clinical procedure; the method further comprising the steps defining an individual path of the clinical procedure by selecting at least one transition between a first and a second clinical state of the clinical data structure (step S3); providing, as input for the geometrical model, a set of values of the geometrical model parameters of the at least one geometrical model for said first and said second clinical states of the defined individual path thereby modelling a first individual pro

TECHNIQUES FOR AUTOMATED MARKING OF DENTAL APPLIANCES

Resumen de: US20260233338A1

The present disclosure discusses techniques for marking a dental appliance. A dental model and dental appliance are positioned onto a conveyor tray, which is transported to a scan station. The dental model and conveyor tray each include an identifying code. The scan station includes a camera and barcode reader to read the identifying codes on the dental model and conveyor tray, and these codes are associated with one another. The conveyor tray then moves to a marking station where a barcode reader reads the code on the conveyor tray, and then marks the dental appliance with the appropriate marking.

APPARATUS AND METHOD FOR AUTOMATIC ULTRASOUND SEGMENTATION FOR VISUALIZATION AND MEASUREMENT

Resumen de: US20260232296A1

A system and method for performing ultrasound scans is provided. One embodiment of the ultrasonographic system acquires sonogram information from a series of ultrasonic scans of a human subject. The series of ultrasound scans are taken over a portion of interest on the human subject which has their underlying bone structure or other ultrasound discernable organ that is under examination. The data from the series of scans are synthesized into a single data file that corresponds to a three-dimensional (3D) image and/or 3D model of the underlying bone structure or organ of the examined human subject.

TECHNIQUES FOR IDENTIFYING REPRESENTATIVE PPG PULSES

Resumen de: US20260232212A1

0000 Methods, systems, and devices for identifying representative photoplethysmogram (PPG) pulses are described. A method may include acquiring a first set of PPG pulses from a user via a wearable device. The method may include comparing a set of morphological features of the first set of PPG pulses, and determining one or more PPG profiles for the user, where the one or more PPG profiles each include a set of morphological value ranges for the set of morphological features. The method may include acquiring a second set of PPG pulses from the user via the wearable device, and determining that one or more PPG pulses from the second set of PPG pulses match the one or more PPG profiles. The method may include determining one or more physiological metrics associated with the user based on the one or more PPG pulses matching the one or more PPG profiles.

METHOD, SYSTEM AND COMPOUND FOR THE AUTOMATED, SOFTWARE-BASED MANUFACTURING OF A VENEER OF A FIXED DENTAL PROSTHESIS

Resumen de: US20260232414A1

0000 A method and a system for the automated, software-based manufacturing of a veneer of a fixed dental prosthesis by coating a dental preform with at least one compound forming a ceramic paste that reproduces the dentin of a natural tooth. The preform is coated based on a 3D layer structure in which each layer is divided into volume elements. Each volume element is filled with a portion of the ceramic paste by aligning the preform with a manipulator so that a ground surface of the volume element to be filled, at an application point on the ground surface, is oriented substantially perpendicular to an ejection direction with the application point lying on the ejection direction. A print head applies the respective portion of the paste by jerking a valve element so that the portion is formed and projected in a coherent manner toward the application point and fills the volume element in a punctiform manner. The compound used is a ceramic paste formed from a powder of a feldspar ceramic finely dispersed in a solvent and including amounts of ammonium polyacrylate, ethoxylated castor oil and traces of urea.

Therapiesystem und Verfahren zu einer Behandlung eines flächigen Körperbereichs eines Lebewesens mit therapeutisch wirksamen Wellen

Resumen de: DE102025104781A1

Die Erfindung geht aus von einem Therapiesystem (58) zu einer nicht-chirurgischen Behandlung zumindest eines flächigen Körperbereichs (10) eines Lebewesens, mit einer Applikatoreinheit (12), aufweisend einen Therapiekopf (14) zu einer Applizierung propagierender physikalischer therapeutisch wirksamer Wellen an dem flächigen Körperbereich (10), und ein Trackingsystem (16), welches dazu vorgesehen ist, während mehrerer Behandlungsabschnitte (18, 20) der Behandlung des flächigen Körperbereichs (10) momentane 3D-Positionsdaten (30, 32) der Applikatoreinheit (12) zu ermitteln.Es wird vorgeschlagen, dass das Therapiesystem (58) eine Recheneinheit (22) mit Zugriff auf ein 3D-Ausgangsmodell (26) eines Körperteils (28) eines Lebewesens, aufweist, wobei die Recheneinheit (22) dazu vorgesehen ist, die von der Trackingsystem (16) erfassten 3D-Positionsdaten (30, 32) der Applikatoreinheit (12) zu empfangen, und basierend auf den empfangenen 3D-Positionsdaten (30, 32) eine von dem 3D-Ausgangsmodell (26) ausgehende Oberflächenapproximation (34) des Körperteils (28) mit dem der Behandlung unterzogenen flächigen Körperbereich (10) zu berechnen, und die zu einzelnen Behandlungsabschnitten (18, 20) der Behandlung zugehörigen 3D-Positionsdaten (30, 32) Oberflächenpunkten (36, 38) der Oberflächenapproximation (34) zuzuordnen

IMAGE-GUIDED NAVIGATION DEVICES, ADAPTERS AND SYSTEMS WITH OPTICAL DISTANCE SENSOR BASED MARKERLESS REGISTRATION, DEPTH DETECTION, IMAGE-GUIDED PREDICTION AND TRAINING MODELS

Resumen de: WO2026169805A1

A navigation device, adapter, and system enables real-time three-dimensional depth sensing through standard endoscopic and borescopic instruments, including laparoscopes, arthroscopes, cystoscopes, ureteroscopes, bronchoscopes, sinuscopes, and borescopes. A releasable adapter integrates LiDAR or other optical time-of-flight sensors with off-the-shelf endoscopes and surgical cameras to generate sub-millimeter precision surface reconstructions and register those reconstructions to preoperative or intraoperative scans for accurate image-guided procedures, particularly on rigid anatomy. The system supports surgical guidance, augmented reality visualization, distance -based signal normalization, 3D measurement, luminal traversal tracking, and robotic control. Time-of-flight sensing over a selected visible sub-band enables simultaneous acquisition of white-light, fluorescence, and depth data, with calibration workflows for wide field-of-view optics and adaptive software control of focus, illumination, and rendering.

A COMPOSITE NANOFIBROUS SCAFFOLD ENHANCES IN VITRO HEPATOCYTES' DRUG CLEARANCE PROFILES TO ALIGN WITH HUMAN PHYSIOLOGY

Resumen de: WO2026170003A1

An in vitro 3D hepatocyte model that contains a nanofibrous scaffold designed to mimic the extracellular matrix (ECM) of the human liver, both structurally and biochemically, is described. HepaRG hepatocytes cultured on the 3D scaffold exhibited enhanced metabolic activity compared to traditional 2D cultures, indicating improved hepatocyte functionality. This model offers a physiologically relevant platform for hepatocyte studies, underscoring the model's potential to advance preclinical drug development by replicating liver-specific functions in vitro.

MULTIVALENT POLYESTER BASED POLYURETHANE ACRYLATE OR METHACRYLATE OLIGOMERS FORMULATED WITH DIFFERENT REACTIVE DILUENTS

Resumen de: US20260232541A1

The present disclosure provides novel oligomers and polymerizable compositions comprising the same. Further provided herein are methods of producing polymers, polymer coatings, and devices. Also provided herein are methods of using polymer materials and polymer materials fabricated via additive manufacturing processes (e.g., via 3D printing), such as orthodontic appliances.

Verfahren zur Herstellung eines Individual-Zahnimplantats

Resumen de: DE102025105136A1

Die Erfindung betrifft ein Verfahren zur Herstellung eines Individual-Zahnimplantats gekennzeichnet durch folgende Schritte:- die Kiefer- und Zahnreihen oder eine Abformung der Kiefer- und Zahnreihen wird digital als erste Information an einem Behandlungsort erfasst;- die Knochen-Hartgewebsstruktur wird zwei- oder dreidimensional geröntgt und digital als zweite Information an dem Behandlungsort erfasst;- die erste Information und die zweite Information werden einem zentralen Datenpool zur Abspeicherung und Bearbeitung in einer Bearbeitungsstation an dem Behandlungsort zugeführt;- auf dem zentralen Datenpool ist eine künstliche Intelligenz (KI) vorhanden, wobei die kI in Abgleich der ersten Information und der zweiten Information eine Fehlsituation ermittelt, und diese Fehlsituation in Abhängigkeit von der ersten Information und der zweiten Information ermittelt und durch das Individual-Zahnimplantat substituiert, wobei eine Form, eine Größe, eine Position und eine Oberflächenstruktur sich an der ersten Information orientiert, geeignet, dass das Individual-Zahnimplantat die Funktion eines natürlichen Zahns oder einer natürlichen Zahnwurzel optimal nachbildet.

SYSTEMS AND METHODS FOR ANALYZING SPECTRAL DATA TO DETERMINE ANALYTE CONCENTRATIONS IN A BODY

Resumen de: US20260232228A1

The methods can include receiving calibrating spectral data from a non-invasive measurement device, known measurement data that is indicative of a concentration of a particular biomolecule in the body of the wearer and was obtained contemporaneously with the calibrating spectral data; generating a signature for the wearer by at least determining, via a neural network, one or more correspondences between or among the calibrating spectral data and the known measurement data; and storing the signature. The methods can include receiving present spectral data from the non-invasive measurement device and processing the present spectral data using the signature to estimate a present concentration of the particular biomolecule in the body.

3D POLYCATENATED ARCHITECTED MATERIALS AND RELATED COMPOSITIONS METHODS AND SYSTEMS

Resumen de: US20260232870A1

Described are 3D polycatenated architected materials, systems, and methods. The material comprises discrete unit particles mechanically interlocked to form a 3D network patterned after a crystalline topology. This structure provides a tunable dual mechanical response, transitioning from a fluid-like regime to a solid-like regime at a programmable “critical jamming strain.” Methods are disclosed for designing the material using a closed-loop digital twin, manufacturing the material via additive processes, and preconditioning the material. Methods and systems for actuating the material using mechanical, electrostatic, magnetic, thermal, or environmental triggers are also disclosed. Further disclosed are kits-of-parts for assembling the material, and end-user systems, such as impact protection systems, soft robotics, and medical implants, incorporating the material.

Extended Hand Training Device

Resumen de: US20260232243A1

An extended hand training device and corresponding method are used for sensing and measuring a capacitance corresponding to the pressure or force applied by the hand or fingers of the user.This extended hand training apparatus has protruded slots for the thumb finger, index finger, the middle finger, the ring finger, and the pinky finger. The data obtained from the device can be utilized to create a 3-D model to indicate grip strength or pull force exerted by the hand.

PROCEDURES FOR ASSISTING GUIDANCE OF A PACING ELECTRODE

Resumen de: US20260233014A1

0000 A method of a machine-assisted cardiac pacing electrode placement procedure in a patient in need thereof is provided. The method comprising identifying a target location using a 3D data set of a heart of the patient, wherein the target location is identified based on anatomical landmarks, the 3D data set having been acquired using data collection from outside the heart; and providing machine-assisted guidance of the pacing electrode to the target location. Also provided are apparatus and systems for executing the method or parts thereof.

AUTOMATIC DETECTION-THERAPY SYSTEMS FOR NEUROPSYCHIATRIC DISORDERS

Resumen de: US20260233010A1

0000 An extended auricular electroencephalogram (EEG) monitoring system has a processing unit configured to analyze EEG data to detect neuropsychiatric disorders and impending neuropsychiatric disorders. An automatic detection-therapy system includes the auricular EEG monitoring system and one or more neuromodulation units. When presence of EEG signals suggestive of a neuropsychiatric disorder or an impending neuropsychiatric disorder is detected by the processing unit, the neuromodulation unit is configured to immediately start neuromodulating electric stimulation automatically to one or various combinations of the following: auricular branch of vagus nerve, supraorbital nerve, infraorbital nerve, auriculotemporal nerve, occipital nerve and greater auricular nerve to alleviate or abort the condition. A combined neuromodulation system having two or three neuromodulating components with synergistic effect is useful for health maintenance and prophylaxis of neuropsychiatric disorders. These earbud-shaped systems, with automated setup designs, are wearable, user-installable, user-removable and freely ambulatory.

ORAL CARE SYSTEM

Resumen de: WO2026169906A1

A patient care delivery system including a first kit including a first tool, and a dock assembly including a base, an arm coupled to the base and extending from the base, a first sensor disposed within the base or the arm, an indicator positioned on the base or the arm, and a processing circuit disposed within the base or the arm. The processing circuit includes a memory and one or more processors. The one or more processors are configured to receive a first signal from the first sensor when the first kit is at least one of coupled to the arm, suspended in front of the arm, or adjacent to the arm, after receiving the first signal, cause the indicator to provide a first indication to a user, and after not receiving the first signal, cause the indicator to provide a second indication to the user.

DEVICE FOR CONVEYING MEDICATION SACHETS

Resumen de: US20260232536A1

A device conveys medication sachets. The device includes an inlet for receiving the medication sachets, an outlet for discharging the conveyed medication sachets, a first endless belt, first guide elements arranged to guide the first endless belt along a first path. First guide elements include a first guide roller, a second endless belt, a plurality of second guide elements arranged to guide the second endless belt along a second path. The second guide elements include a second guide roller, a plurality of third guide rollers arranged to guide the first endless belt and the second endless belt along a third path. The medication sachets are conveyed between the first endless belt and the second endless belt along the third path from the inlet to the outlet. A device rotates at least one of the first, second or third guide rollers. A medication dispenser dispenses the medication sachets.

METHOD AND DEVICE FOR GENERATING DIGITAL ELECTROCARDIOGRAM SIGNAL

Resumen de: WO2026169117A1

The present disclosure relates to a method and a device for generating a digital electrocardiogram signal on the basis of an electrocardiogram record. According to an embodiment of the present disclosure, a method for generating a digital electrocardiogram signal on the basis of an electrocardiogram record is provided, the method including the steps of: performing preprocess to extract first electrocardiogram information on the basis of a first electrocardiogram record; training an artificial intelligence segmentation model on the basis of the first electrocardiogram record and the first electrocardiogram information; segmenting a second electrocardiogram record into second electrocardiogram information by using the second electrocardiogram record as an input of the trained artificial intelligence segmentation model; and converting the segmented second electrocardiogram information into a digital electrocardiogram signal.

SYSTEMS AND METHODS FOR ANALYSING ELECTROCARDIOGRAMS USING DEEP LEARNING

Nº publicación: AU2025224889A1 13/08/2026

Solicitante:

THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
NEWYORK PRESBYTERIAN
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
NEWYORK-PRESBYTERIAN

Resumen de: AU2025224889A1

Provided is a system and method for detecting cardiac abnormalities from electrocardiogram (ECG) data. The system provides an automated ECG platform comprised of standard medical equipment and modules for data acquisition, processing, analysis, interpretation, and a user interface, which can be integrated into existing clinical contexts. The method includes receiving ECG data from a patient, analyzing the data using a trained convolutional neural network (CNN) model to detect predetermined cardiac conditions, and generating an output indicating the presence of these conditions. The CNN model is developed through a deep learning process that includes collecting ECG-echocardiogram pairs from multiple patients, curating the collected data, training the CNN model with the curated data, validating model performance, testing model generalization, and generating diagnostic predictions with confidence scores.