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Microalgas: Cultivo e usos

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口腔支架及其制造方法

NºPublicación:  CN123059297A 10/11/2026
Solicitante: 
山西医科大学第一医院
CN_123059297_PA

Resumen de: CN123059297A

本发明公开了一种口腔支架及其制造方法,属于医疗器械技术领域。口腔支架包括基座、第一连接件、第二连接件、第一牙弓放置体和第二牙弓放置体;基座第二表面呈拱形隆起形成容置区,第一连接件和第二连接件分别自基座两侧延伸并连接两牙弓放置体,两牙弓放置体分离并形成通气通道,且均设上牙弓放置槽和下牙弓放置槽。制造方法包括:获取分割数据,生成基座、牙弓放置体、连接件和推颊件,布尔合并后输出3D打印格式文件,经3D打印后获得口腔支架。本发明通过基座与牙弓放置体分离设计,有效避免舌体卷缩的不足,同时双重咬合固定提高定位精度,实现了量化设计与自动化制造。

一种3D打印可降解抗菌促成骨的口腔生物膜及制备方法

NºPublicación:  CN123059213A 10/11/2026
Solicitante: 
吉林大学
CN_123059213_PA

Resumen de: CN123059213A

本发明公开了一种3D打印可降解抗菌促成骨的口腔生物膜及制备方法,属于生物医学工程、增材制造与口腔临床医学交叉技术领域。生物膜为双层复合结构,包括外层致密阻隔层与内层复合功能层;外层为无孔隙的生物可降解高分子致密层,内层包括带规则孔隙阵列的高分子基底及负载纳米氧化镁和亚精胺的功能水凝胶,水凝胶渗入孔隙固化后形成榫卯式机械联锁结构。制备方法包括:S1、功能性水凝胶生物墨水的制备;S2、生物膜的3D打印;S3、成品制备完成。本发明共负载纳米氧化镁与亚精胺,两者协同发挥抗菌促成骨作用,榫卯结构显著提升层间界面粘附牢度,并保障活性成分长效稳定释放。

义齿制作方法、用于义齿用模具的设计方法及模具组件

NºPublicación:  CN123058852A 10/11/2026
Solicitante: 
广州黑格智造信息科技有限公司
CN_123058852_PA

Resumen de: CN123058852A

本申请适用于牙科修复体制造技术领域,提供了一种义齿制作方法、用于义齿用模具的设计方法及模具组件,该方法包括:通过预设方式获取颌位记录工具,预设方式包括以下之一:通过将三维打印得到的第一模具填充成型材料成型得到颌位记录工具,或直接通过三维打印得到颌位记录工具。基于将颌位记录工具置入目标对象的口腔内,获取目标对象的口腔颌位关系数据。根据口腔颌位关系数据,通过三维打印得到第二模具。通过第二模具制作得到目标义齿。该方法通过三维打印第一模具或颌位记录工具以及第二模具来制备目标义齿,显著降低了对操作人员的经验依赖、减少了中间义齿的调整次数并能够得到制造精度更高的义齿。

用于借助于熔融沉积建模来增材制造3D物品的方法以及增材制造装置

NºPublicación:  CN123076486A 10/11/2026
Solicitante: 
默克专利股份公司
CN_123076486_PA

Resumen de: WO2025214921A1

The invention relates to a method and an apparatus (1) for additive manufacturing of a 3D item (2) by means of fused deposition modeling of a composite material, whereby the composite material is fed through a heated printer extruder head (4) and deposited on a printer bed (3) as a layer arrangement that form the 3D item (2). The composite material is provided as at least one rigid rod (10) that is conveyed out of a rod magazine (9) that is capable of storing at least one rigid rod (10). The rigid rod (10) is then conveyed through a guide tube (15) that is arranged within the printer extruder head (4), whereby the rigid rod (10) is heated during the conveyance through the guide tube (15), and whereby the heated and viscous composite material is discharged through a discharge nozzle (16) at one end of the guide tube (15) and deposited as the layer arrangement onto the printer bed (3) to generate the 3D item (2).

牙冠模型生成方法以及牙冠模型生成系统

NºPublicación:  CN123076357A 10/11/2026
Solicitante: 
德睿生医股份有限公司
CN_123076357_PA

Resumen de: TW202631088A

The present invention provides a dental crown model generation method and a dental crown model generation system. The method includes: retrieving preset dental shape data including multiple geometric features based on the target position of the treated tooth; adjusting the preset dental shape using rotation, stretching, and translation parameters to obtain the adjusted geometric features; scoring the matching degree between the adjusted geometric feature and multiple conditional operations; performing weighted calculations on the scores to obtain a dental score; if the dental score is below a threshold score, inputting the dental score into a parameter correction artificial intelligence unit to obtain new rotation, stretching, and translation parameters, and continuing the adjustment until the dental score exceeds the threshold score; and using the dental shape corresponding to the final parameters as the final dental crown model for the patient.

Methods and systems for computer-aided surgery using intra-operative video acquired by a free moving camera

NºPublicación:  USRE51111E 10/11/2026
Solicitante: 
SMITH & NEPHEW INC [US]
Smith & Nephew, Inc.
US_RE51111_E

Resumen de: USRE51111E

Disclosed is a concept for computer-assisted procedures of surgery and diagnosis that target rigid, non-deformable anatomical parts such as bone, tissue, or teeth. The disclosure describes attaching small visual markers to instruments and anatomy of interest (e.g. bone surface), with each marker having a printed known pattern for detection and unique identification in images acquired by a free-moving camera, and a geometry that enables estimating its rotation and translation with respect to the camera using solely image processing techniques.

一种钛钼锆预合金粉末及其制备方法、齿科修复体及其制备方法

NºPublicación:  CN123043371A 06/11/2026
Solicitante: 
南京铖联激光科技有限公司
CN_123043371_PA

Resumen de: CN123043371A

本发明涉及一种钛钼锆预合金粉末及其制备方法、齿科修复体及其制备方法,属于生物医用金属材料技术领域。其中,钛钼锆预合金粉末,按质量百分比计,其化学成分包括:Mo:12%~20%,Zr:4%~10%,O:≤0.15wt%,N:≤0.035wt%、H:≤0.008wt%,余量为Ti及不可避免的杂质。本发明提供的钛钼锆预合金粉末,不含Al、V元素,能够消除Al、V元素的生物安全性隐患,并实现同一材料既满足烤瓷冠桥金属基底的强度与瓷结合要求,又满足带卡环可摘支架的回弹性与塑性要求。

高密度扩散光学断层成像方法及系统

NºPublicación:  CN123037692A 06/11/2026
Solicitante: 
澳门大学
CN_123037692_A

Resumen de: CN123037692A

本申请提供一种高密度扩散光学断层成像方法及系统,属于光学成像技术领域。该方法包括:基于目标受试者的立体头部模型,确定目标受试者的头部几何信息,并根据头部几何信息,打印生成适用于目标受试者的采集帽,采集帽上包括多个近红外光探头;通过采集帽上的多个近红外光探头对目标受试者的待测脑区进行扫描,以采集待测脑区的时间分辨光信号;基于时间分辨光信号进行图像重建,以生成并显示目标受试者的高分辨率脑图像。本申请可以达到提高信号采集效率和空间分辨率,降低设备使用难度,并统一重建图像流程,以提高成像稳定性和可靠性的效果。

一种微气泡增强型复合脂质体、3D打印墨水及制备方法

NºPublicación:  CN123038344A 06/11/2026
Solicitante: 
山西师范大学
CN_123038344_PA

Resumen de: CN123038344A

本发明公开了一种微气泡增强型复合脂质体、3D打印墨水及制备方法,涉及生物医用材料与微创增材制造技术领域;复合脂质体包括脂质双分子层、包裹在脂质双分子层内的微气泡和交联剂;脂质双分子层为磷脂酰胆碱、胆固醇、PEG化脂质的任意组合;复合脂质体采用微流控芯片连续流制备,通过复合脂质体制备3D打印墨水;本发明将微气泡封装于脂质体内部,利用微气泡气体核心在超声场中的声空化效应产生的局部机械应力,直接驱动脂质双分子层的瞬时孔道形成和交联剂释放,消除了热损伤风险;解决了3D打印生物墨水固化成型安全稳定性差、成型精度不足的问题。

一种柔性肌电电极阵列及其3D打印方法

NºPublicación:  CN123037748A 06/11/2026
Solicitante: 
苏州昀感智能科技有限公司
CN_123037748_PA

Resumen de: CN123037748A

本发明提供一种柔性肌电电极阵列及其3D打印方法,该方法包括:获取3D扫描仪采集的四肢肌电采集体表区域的三维点云数据,并输入三维几何建模平台后根据肌电采集需求生成包括电极阵列排布、触点位置与导线路径的三维数字模型;对三维数字模型按照预设分层厚度进行分层切片获得柔性基底、导电线路、电极触点和水凝胶修饰层,并生成打印路径;采用多材质复合三维打印装置根据打印路径依次获得目标打印模型;对目标打印模型进行全域紫外光固化,经等离子体对目标打印模型进行亲水性改性处理后获得柔性肌电电极阵列。实现柔性肌电电极阵列的一体化成型并提高柔性肌电电极阵列的佩戴舒适性和数据采集准确性。

一种用于经颅超声神经调控定位笼的制造方法及系统

NºPublicación:  CN123040352A 06/11/2026
Solicitante: 
电子科技大学
CN_123040352_A

Resumen de: CN123040352A

本发明涉及医疗器械领域,具体涉及了一种用于经颅超声神经调控定位笼装配系统及方法。通过将医学影像规划结果转化为三维打印结构,使设计的定位笼本身成为治疗计划的物理载体。通过对预留孔位的设计,对不同换能器模块之间的声程差进行机械预补偿,使换能器能完成预制,兼顾个体化适配和工业化生产,有利于降低成本。通过水囊式耦合组件提供稳定声学耦合,并可进一步通过压力、气泡和回波检测提高经颅超声神经调控安全性。可减少对大型机械臂和高通道数全阵列头盔的依赖,为经颅超声神经调控设备的小型化、低成本化和临床普及提供新的工程路径。

硝子体網膜及び白内障システム用の吸引及び注入接続インジケータライト

NºPublicación:  JP2026537201A 06/11/2026
Solicitante: 
アルコンインコーポレイティド
JP_2026537201_A

Resumen de: WO2025093948A1

Certain embodiments disclosed herein provide an ophthalmic surgical system. The system includes a fluidics module and a controller. The fluidic module includes a surgical cassette bay and one or more indicator lights. The one or more indicator lights correspond to one or more fluidic ports on the fluidics module. The controller includes a memory including executable instructions and a processor. The processor is in data communication with the memory. The processor is configured to execute the instructions to cause the system to: determine that a surgical cassette is coupled to the surgical cassette bay; determine a type of the surgical cassette; illuminate at least one of the one or more indicator lights based on the determined type of the surgical cassette; and extinguish the at least one of the one or more indicator lights upon receiving an input indicating that a fluidic tubing is fluidically coupled with the corresponding fluidic port.

薬剤仕分装置

NºPublicación:  JP2026178405A 06/11/2026
Solicitante: 
株式会社湯山製作所
JP_2026178405_A

Resumen de: US20250099338A1

0000 A drug sorting apparatus with reduced packaging time is provided. A drug sorting apparatus includes: a second accommodating portion in which a plurality of sorting cups are arrangeable, the plurality of sorting cups being configured to accommodate a plurality of types of drugs in a state of being sorted by type; a packaging mechanism configured to package a drug, which is accommodated in the accommodating portion; a first dispensing mechanism configured to dispense, for each of the plurality of sorting containers, the drug accommodated in the accommodating portion to the packaging unit; and a container takeout mechanism configured to take out a sorting container from the accommodating portion so as to deliver the sorting container to the first dispensing mechanism, wherein the first dispensing mechanism is configured to tilt the sorting container received from the container takeout mechanism, to thereby dispense the drug accommodated in the sorting container to the packaging unit.

一种微孔3D打印聚乳酸支架的制备方法

NºPublicación:  CN123038342A 06/11/2026
Solicitante: 
大连理工大学大连市第三人民医院
CN_123038342_A

Resumen de: CN123038342A

本发明公开了一种微孔3D打印聚乳酸支架的制备方法,所述的方法有两步:第一步是通过无机盐颗粒加入聚乳酸的有机溶液中搅拌得到含有无机盐颗粒聚乳酸原液;第二步是将聚乳酸原液经过3D打印在水相刻蚀溶液中进行模板溶出法,由此实现具有微孔的3D打印聚乳酸支架。该发明通过改变无机盐颗粒、有机溶剂以及水相刻蚀溶液,提供了一种实现聚乳酸材料物理致孔的方法。被认为是一种绿色可控、潜力巨大的聚乳酸材料致孔方法。

正畸制品及其制备方法和非暂态机器可读介质

NºPublicación:  CN123042255A 06/11/2026
Solicitante: 
舒万诺知识产权公司
CN_123042255_PA

Resumen de: WO2020104873A1

In one embodiment, an orthodontic article is described comprising the reaction product of a polymerizable composition comprising: a) 30-70 parts by weight of monofunctional (meth)acrylate monomer, wherein a cured homopolymer of at least one monofunctional (meth)acrylate monomer has a Tg of at least 30, 35, 40, 45, 50, 55, or 60°C; and b) urethane (meth)acrylate polymer comprising polymerized units of an aliphatic polyester diol. Also described are polymerizable compositions, as well as methods and systems for making an article utilizing 3D printing.

相分离材料的3D打印复合物

NºPublicación:  CN123042453A 06/11/2026
Solicitante: 
阿莱恩技术有限公司
CN_123042453_A

Resumen de: US20250066525A1

0000 The present disclosure provides methods, systems, devices, and kits for creating composite materials from a single resin, the composite materials having multiple continuous phases. The disclosure includes a process to three-dimensionally print objects (e.g., orthodontic appliances) with composite properties. In some aspects, the composite properties are formed from a single formulation with components that, when processed, have hard and soft continuous phases. In some aspects, the composite properties are formed by separately processing the hard phase components and the soft phase components. In some aspects, the composite materials and devices are three-dimensionally printed using the processed material.

移動設定された歯牙モデルの補正による矯正装置の設計方法

NºPublicación:  JP2026537091A 05/11/2026
Solicitante: 
オーディーエスカンパニーリミテッド
JP_2026537091_A

Resumen de: WO2025079952A1

The present invention is a method for designing an orthodontic device by using a computer, comprising the steps of: (S01) displaying a teeth arrangement image; (S02) correcting an arrangement state of teeth in the teeth arrangement image; (S03) correcting the shape of teeth in the teeth arrangement image; (S04) displaying the orthodontic device on a screen according to the corrected teeth arrangement image; and (S05) outputting the orthodontic device by using a 3D printer.

GENERATION OF SYNTHETIC RADIOLOGICAL IMAGES

NºPublicación:  US20260345103A1 05/11/2026
Solicitante: 
BAYER AG [DE]
BAYER AKTIENGESELLSCHAFT
US_20260345103_A1

Resumen de: US20260345103A1

The present invention relates to the technical field of radiology, and in particular to assisting radiologists in radiological examinations using artificial intelligence methods. The present invention relates to training a machine learning model and using the trained model to predict representations of an examination area after applications of different amounts of contrast agent.

Methods and Devices To Detect Poor Cerebral Blood Flow In Real-Time To Prevent Dizziness, Fainting, and Falls

NºPublicación:  US20260345093A1 05/11/2026
Solicitante: 
LUMIA HEALTH INC [US]
Lumia Health, Inc.
US_20260345093_A1

Resumen de: US20260345093A1

A method of preventing presyncope, syncope and falls in a subject for execution by a wearable device that includes one or more processors. The method comprises generating, by one or more biometric sensors of the wearable device, biometric data regarding the subject, wherein the wearable device is configured to attach to an ear of the subject, wherein the wearable device is sized to be less than 20 mm in the longest dimension and is configured to be positioned entirely outside an ear canal of the ear such that the ear canal remains unobstructed during operation, and wherein the one or more biometric sensors are optical sensors configured to target at least one branch of a posterior auricular artery of the subject to monitor at least one biometric parameter of the subject. The method further comprises aggregating and processing, by the one or more processors, the biometric data to produce processed data; analyzing, by the one or more processors, the processed data to detect or predict an event relating to one or more of: poor cerebral blood flow, poor blood pressure, poor blood volume, poor blood oxygenation, presyncope, syncope, and a fall event; and delivering one or more real-time messages to the subject pertaining to the event.

DIGITAL STOCK WROUGHT WIRE CLASP, REST SEAT, AND ORTHODONTIC LIBRARY FOR 3D PRINTING AND MILLING DENTAL APPLIANCES

NºPublicación:  US20260345298A1 05/11/2026
Solicitante: 
REGENTS OF THE UNIV OF MINNESOTA [US]
Regents of the University of Minnesota
US_20260345298_A1

Resumen de: US20260345298A1

0000 A method of fabricating a removable dental appliance includes the steps of: (a) acquiring 3D digital image data of a patient's mouth and dentition; (b) creating a 3D digital model of a removable dental appliance to be fabricated wherein the 3D digital model incorporates a model clasp and/or model seat selected from a digital library of virtual clasps and/or seats, each of the virtual clasps or seats corresponding to an associated physical clasp or seat; (c) fabricating a portion of the removable dental appliance from the 3D digital model, the portion of the removable dental appliance including an attachment section; (d) selecting a physical clasp or seat that corresponds to the model clasp or seat; and (e) inserting a tail section of a selected physical clasp and/or seat into mounting structure in the attachment section, the tail section being dimensioned to matingly engage the mounting structure.

ADJUDICATION ALGORITHM BYPASS CONDITIONS

NºPublicación:  US20260350440A1 05/11/2026
Solicitante: 
MEDTRONIC INC [US]
Medtronic, Inc.
US_20260350440_A1

Resumen de: US20260350440A1

0000 This disclosure describes techniques for bypassing an algorithm configured to determine a likelihood of episode data being a false indication of a cardiac episode. A medical device system includes processing circuitry configured to receive episode data and determine, based on satisfaction of one or more bypass conditions of a set of bypass conditions, whether to bypass the algorithm. Responsive to bypassing the algorithm, the processing circuitry stores the episode data as a true indication of the cardiac episode.

INTERVENTION OPERATION ROBOT AND SYSTEM FOR INTERVENTION OPERATION CONTROL

Nº publicación: US20260345262A1 05/11/2026

Solicitante:

SHANGHAI UNITED IMAGING HEALTHCARE CO LTD [CN]
SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

US_20260345262_A1

Resumen de: US20260345262A1

The embodiments of the present disclosure provide an intervention operation robot and a system for intervention operation control. The system comprises: an injection auxiliary device configured to assist an injection instrument for injection; an intervention operation robot configured to convey an intervention instrument; an image acquisition device configured to acquire one or more images; and a control device configured to generate one or more control instructions based on feedback information from at least one of the injection auxiliary device, the intervention operation robot, and the image acquisition device, and send the one or more control instructions to at least one of the injection auxiliary device, the intervention operation robot, and the image acquisition device. The intervention operation robot includes an instrument conveying member and a robotic arm.

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