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Efficient microalgae culture equipment and method

Resumen de: CN120591067A

The invention discloses efficient microalgae culture equipment which comprises a raceway pond structure, a concentric table, an electric belt conveying mechanism, a water stirring lifting mechanism and a circulating ventilation mechanism, a pond body is arranged in the raceway pond structure, the concentric table is arranged in the center of the pond body, and the electric belt conveying mechanism is installed on the concentric table and drives the circulating ventilation mechanism to move along a set track; the water-stirring lifting mechanism is arranged on one side of the tank body and comprises a screw rod for adjusting the height, a lifting block, a sealing sliding plate and a water-stirring impeller, the circulating ventilation mechanism comprises an air compression mechanism, a ventilation pipe, a transverse pipe and an air outlet head, and the air compression mechanism compresses air through a piston assembly and injects the air into the bottom of the tank body through the air outlet head; according to the equipment, the height of the water-repellent impeller is automatically adjusted along with the liquid level through the water-repellent lifting mechanism, the movable air outlet structure is combined to expand the inflation range and prevent blockage, the air compression mechanism realizes efficient one-way air supply through mechanical reciprocating, and the ventilation effect is improved.

Lignocellulose pretreatment liquid resource utilization method based on algal-bacterial co-culture

Resumen de: CN120589942A

The invention discloses a lignocellulose pretreatment liquid resource utilization method based on bacterium-alga co-culture, which comprises the following steps: by taking Kurthia huakuii bacteria and Chlorella sorokiniana microalgae as model microorganisms, establishing an alga-bacterium symbiotic system, inoculating the alga-bacterium symbiotic system into a lignocellulose pretreatment liquid, carrying out phototrophic growth and nitrogen assimilation on the Kurthia huakuii bacteria rapid detoxification inhibitor and the Chlorella sorokiniana microalgae by using bacterial metabolites (organic acid and CO2), and carrying out anaerobic fermentation and nitrogen assimilation on the lignocellulose pretreatment liquid, so as to obtain the lignocellulose pretreatment liquid resource utilization method based on bacterium-alga co-culture. According to the method, toxic substances in lignocellulose pretreatment can be efficiently detoxified, organic carbon in lignocellulose pretreatment liquid is recycled and converted into high-value phycomycete biomass, and the utilization rate of carbon and nitrogen is increased.

Chlorella and application thereof in carbon sequestration, emission reduction and biological fertilizer co-production

Resumen de: CN120591103A

The invention discloses chlorella and application thereof in carbon sequestration and emission reduction and co-production of a biological fertilizer, and a process for coupling carbon sequestration and emission reduction of microalgae and utilization of a microalgae biological fertilizer in flue gas of a power plant comprises the following steps: 1) culturing an algal strain in the flue gas of the power plant, and 2) harvesting the algal strain cultured in the step 1) and using the algal strain to prepare the microalgae biological fertilizer. Through experiments, aiming at the defects of the traditional flue gas treatment technology of the coal-fired power plant, the invention adopts a microalgae carbon sequestration technology which is environment-friendly, economical and efficient and conforms to the natural circulation characteristics, and is coupled with a microalgae biological fertilizer, so that the flue gas treatment is realized, the flue gas resource utilization is realized, the whole ecological chain is prolonged, and the environmental protection is realized. And the full-life-cycle carbon sequestration emission reduction amount is effectively increased.

Preparation method of microalgae bait

Resumen de: CN120584976A

The invention provides a preparation method of microalgae bait, the microalgae bait is prepared through microalgae culture, magnetic separation, microencapsulation wrapping, drying and other methods, during culture, a specific culture solution is added, culture conditions are adjusted, algae liquid cells are separated by adopting a nano magnetic dispersant, effective components in the microalgae cells are ensured, mixed cell sap is screened out, and the microalgae bait is prepared. The components in the core material are wrapped through microencapsulation wrapping, the components of the wall material are used for isolating the external environment, good oxidation resistance and water resistance are achieved, notches and pores of the bait are reduced after wrapping, the performance is stable, the storage life is long, the swelling and collapsing time in water is prolonged, collapsing of nutritional ingredients in the core material is delayed, and the bait has the advantages of being good in stability and good in stability. The loss rate is low, the acid value change rate is within 2.20%, the peroxide value change rate is within 1.41%, the water resistance time reaches 8.5 h, the loss rate is within 4.85%, the sinking rate reaches 98%, the bait is easy to sink into the water bottom and beneficial to being ingested by aquatic animals, and the utilization rate of the bait is increased.

Microalgae species storage rack

Resumen de: CN223304431U

The utility model provides a microalgae species preservation rack. The microalgae species preservation rack comprises a main frame, a containing box, a lighting device and an inflation device. The containing box is installed on the main frame, a containing cavity used for containing a flask is formed in the containing box, and an opening communicated with the containing cavity is formed in the front side of the containing box; the illumination device is mounted on the accommodating box and comprises a plurality of lamp tubes and a switch for controlling the lamp tubes, and the lamp tubes are mounted at the top of the accommodating cavity and provide illumination for microalgae species in the flask in the accommodating cavity; and the air charging device is mounted on the main frame and is used for supplying air to microalgae species in the flasks in the accommodating cavity. The storage rack can ensure the stability and the reliability of a microalgae cultivation environment, and the cultivation protection quality of microalgae is improved.

LED lamp applied to microalgae cultivation

Resumen de: CN223306764U

The utility model relates to the technical field of lighting lamps, in particular to an LED lamp applied to microalgae cultivation, which is characterized by comprising a lamp housing, a lamp panel and a lens, the lamp panel is mounted in the lamp housing, a light source for emitting light is mounted on the lamp panel, and the lens is mounted at an opening of the lamp housing and shields the lamp panel. Therefore, the light emitted by the light source is diffused, and the irradiation range of the light is expanded. The utility model has the advantages that the illumination uniformity is improved, and the exposure is reduced.

GLASS NOODLES WASTEWATER TREATMENT PROCESS BASED ON MICROALGAE

Resumen de: AU2024387147A1

The present invention relates to a glass noodles wastewater treatment process based on microalgae, belonging to the technical field of microbial wastewater treatment. Chlorella sorokiniana NZ1 and Monoraphidium sp. NZ4 are selected. An analysis of experiment results shows that when Chlorella sorokiniana NZ1 and Monoraphidium sp. NZ4 are subjected to mixed culturing, the biomass of both in the wastewater reaches the highest level. At the same time, the removal rates of water quality indicators also exhibit the most significant improvement; specifically, the removal rates of COD, TN, ammonia nitrogen, and TP can respectively reach 83.4%, 91.19%, 81.51%, and 78.71%. Thus, it can be concluded that subjecting the algal strains NZ1 and NZ4 to mixed culturing is the most effective glass noodles wastewater treatment method.

BACTERIA

Resumen de: WO2025181256A1

The invention relates to modified cyanobacterial strains comprising one or more modifications to enhance the rate of carbon dioxide fixation relative to a cyanobacterial strain which does not comprise said modifications.

PRODUCTION OF THERAPEUTIC ANTIBODIES BY THE MICROALGAE PHAEODACTYLUM TRICORNUTUM

Resumen de: US2025277228A1

Monoclonal antibodies represent the most rapidly growing category of the recombinant therapeutic protein pipeline, with more than 85% of the therapeutic indications. The present invention proposes novel vectors that have been optimized so as to produce high levels of monoclonal antibodies when transfected in the microalgae Phaeodactylum tricornutum, as well as optimized culture conditions of said microalgae cells. Altogether, the present invention provides new systems for producing high amounts of monoclonal antibodies, functional fragments or derivatives thereof, in microalgae.

Bacteria

Resumen de: GB2638687A

A modified cyanobacterium comprising one or more genetic modifications for improving expression of aromatic amino acids through overexpression of shikimate pathway to enhance the rate of carbon dioxide fixation relative to a cyanobacterium which does not comprise said genetic modifications. Also disclosed is use of AroF D174N and/or TesA for increasing the rate of carbon dioxide fixation by a modified cyanobacterium. The cyanobacterium can be Synechococcus sp., e.g. Synechococcus 11901 or a variant thereof. The modified cyanobacterium can comprise one or more genetic modifications to over-express shikimate kinase (SK) in the modified cyanobacterium.

EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR BIODISTRIBUTION UPON INTRANASAL ADMINISTRATION, AND USES THEREOF

Resumen de: WO2024088808A1

Provided are compositions containing microalgae extracellular vesicles (MEVs) formulated for intranasal delivery, whereby, upon intranasal administration the MEVs traffic through specific routes following intranasal administration to specific regions in the brain via the olfactory nerve and throughout the lateral olfactory tract (LOT) to interconnected brain regions. The MEVs traffic via neuronal axonal transport. The MEVs have the ability to cross-over synapses including: (i) the synapses between the olfactory sensory neurons (OSN) and the mitral/tufted neurons; (ii) the synapses between the mitral/tufted neurons and the local neurons in the various brain regions colonized by the lateral olfactory tract (LOT); and (iii) the synapses between the neurons in the brain regions colonized by the LOT and neurons from the frontal cortex, the hippocampus, the thalamus, and the hypothalamus. The compositions contain extracellular vesicles from microalgae (MEVs) that are loaded with bioactive cargo for treating, detecting, diagnosing, or monitoring a disease, disorder, or condition of the brain or involving the brain, particularly providing neuronal delivery of the cargo. The compositions and methods have a variety of applications as therapeutics and diagnostics for treating, diagnosing, and monitoring a disease, disorder, or condition of the brain or involving the brain. The compositions can be used in methods and uses for treating cancers involving the brain, and can be used, for exa

Preparation method of quaternary composite gel culture medium for three-dimensional culture of cyanobacteria

Resumen de: CN120574730A

The invention discloses a preparation method of a quaternary composite gel culture medium for three-dimensional culture of cyanobacteria, and the quaternary composite gel culture medium realizes the balance of porosity and mechanical strength through the synergistic effect of mechanical support of polyvinyl alcohol, dual crosslinking of sodium alginate/cyanobacteria polysaccharide and pore regulation of plant cellulose/bicarbonate. Three-dimensional high-density culture can be supported, and the biomass concentration can be improved when the culture medium is combined with a basic culture solution.

Biological treatment method of ammonia-nitrogen wastewater

Resumen de: CN120573867A

The invention belongs to the technical field of water treatment, and particularly relates to a biological treatment method of ammonia-nitrogen wastewater. Comprising the following steps: preparing a carbon-ytterbium-doped cerium dioxide polyhedron; preparing a composite optical dispersion liquid; treating and modifying the corn straws; domesticating the microalgae and treating the ammonia-nitrogen wastewater. According to the invention, the cerium dioxide polyhedron coated with the cellulose nanocrystal film is loaded on the surface of the corn straw, when light irradiates the surface of the cellulose nanocrystal film, due to the difference of internal refractive indexes, the light is subjected to a series of refraction and reflection; transmission of light in wastewater, optically modified straw carriers and a microalgae system can be greatly enhanced, the situation that too much carriers shield light in a subsequent microbial tank is avoided, a large number of carriers with small sizes can be added without affecting microalgae growth, the contact area of the carriers with wastewater and microalgae is increased, more micromolecular organic carbon is released, and the yield of microalgae is increased. The growth and the activity of the microalgae are promoted, so that the efficient treatment on the ammonia-nitrogen wastewater is realized.

Compound microbial agent for repairing uranium-contaminated soil and application thereof

Resumen de: CN120574709A

The invention provides a compound microbial agent for repairing uranium-contaminated soil and application of the compound microbial agent for repairing the uranium-contaminated soil, and the compound microbial agent for repairing the uranium-contaminated soil is prepared by mixing micromycobacterium and bacillus cereus. Through microbial agent treatment, the inhibition effect on seed germination of the sudangrass is remarkably relieved, and the plant biomass, the stress-resistant enzyme activity, the uranium enrichment coefficient, the total biomass of the sudangrass, the total nitrogen content of soil and the rapidly available phosphorus content are also remarkably improved; in the aspect of uranium pollution remediation efficiency, the complex microbial inoculants can reach 20%; the activity of beta-glucosidase is respectively improved by 10.57%-42.47%, and the activity of urease and the activity of catalase are also synchronously improved; the abundance of proteobacteria and cyanobacteria in a microbial community structure is obviously increased. According to the technical scheme provided by the invention, a uranium pollution treatment mode of'functional fungicide-rhizosphere micro-ecological regulation-plant synergistic remediation 'is constructed. A new thought and method are provided for repairing the uranium-polluted soil, and a scientific basis and a feasible repairing scheme are provided for subsequent large-scale application.

Application of mucilaginoidea in soil improvement and crop growth promotion

Resumen de: CN120574577A

The invention relates to the field of agriculture, and discloses application of mucilaginella in soil improvement and crop growth promotion. It is found that compared with other microalgae, the mucilaginoidea can more remarkably improve the physical and chemical properties of soil, and meanwhile, the saline-alkaline resistance and drought resistance of crops can be remarkably improved. Therefore, the mucilaginoidea can play a greater role in promoting the growth of crops in stress environments such as salt and alkali, drought and the like.

Methanol-tolerant Eimerella lipenosa mutant strain as well as screening method and application thereof

Resumen de: CN120574677A

The invention provides a methanol-tolerant Eimenococcus sp. Mutant strain as well as a screening method and application thereof, the methanol-tolerant Eimenococcus sp. Mutant strain is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC M 20232483. The mutant strain can effectively utilize an industrial byproduct methanol as a carbon source to carry out efficient protein production and valuable carotenoid accumulation; the mutant strain shows excellent photosynthesis capability and nitrogen assimilation efficiency under a methanol culture condition. Effective technical support is provided for methanol-based industrial biological refining application of microalgae, and the method has remarkable environmental and economic benefits.

Biochar-based microalgae fertilizer, preparation method and application

Resumen de: CN120554161A

The invention provides a charcoal-based microalgae fertilizer as well as a preparation method and application thereof, the method adopts a mode of co-fermentation of charcoal and microalgae to fix microalgae on charcoal, and co-fermentation is performed to prepare the charcoal-based microalgae fertilizer. The biochar-based microalgae fertilizer can significantly improve the crop yield, increase the chlorophyll content of crops, promote healthy growth of plants, optimize the pH value of soil, enhance the water and fertilizer retention capacity of soil, and significantly improve the soil nutrients and soil enzyme activity, and has significant advantages in the aspects of nutrition supply, soil health, environmental protection, crop quality improvement and the like. The biochar-based microalgae fertilizer has two forms of liquid and dry powder, can be flexibly used according to a specific agricultural production mode, has the advantages of easily available raw materials and simple preparation, is a sustainable fertilizer source, can comprehensively improve the soil fertility and the crop stress resistance, reduces the dependence on chemical fertilizers, and reduces the environmental pollution problem in agricultural production.

Closed double-layer stirring type photobioreactor

Resumen de: CN120555143A

The invention discloses a closed double-layer stirring type photobioreactor, and relates to the technical field of microalgae culture. A double-layer special-shaped paddle combination is formed through the composite design of a four-straight-blade overall open turbine type (SK) and a three-blade left-handed push type spiral stirring paddle (TXL), paddle combination optimization is formed through the cooperative flow field design of the TXL paddle (lower layer) and the SK paddle (upper layer), axial-radial flow coupling is achieved, and the material exchange rate between gas and liquid is increased; according to the combined design of the double-layer special-shaped paddles, the proportion of a high-shear area is reduced to be lower than 12% through a wide-area low-strength shear mode of the TXL paddles, the shear stress is greatly reduced, and the problem that the shear stress is too high is solved; a dynamic rotating speed strategy is convenient to implement, and the mass transfer efficiency and the cell activity are both considered by adjusting the rotating speed in stages.

Synechococcus capable of resisting high-concentration carbon dioxide as well as preparation method and application of synechococcus

Resumen de: CN120555194A

The invention belongs to the technical field of biology, and relates to a synechococcus resistant to high-concentration carbon dioxide and a preparation method and application of the synechococcus resistant to high-concentration carbon dioxide, and the synechococcus resistant to high-concentration carbon dioxide comprises CRISPR/dCas9 plasmids, gRNA plasmids and knockout omega plasmids. According to the invention, PEPC is transcriptionally activated through a CRISPR/dCas9 system, so that PCC7942 can grow under the condition of high-concentration CO2. Besides, the fusion between the omega subunit of RNAP and a Cas9 nuclease mutant directionally combined with an upstream promoter region can realize programmable transcriptional activation, and the growth and carbon sequestration efficiency of microalgae under high-concentration CO2 is improved by knocking out the omega subunit and utilizing a CRISPR/dCas9 transcriptional regulation system to optimize a photosynthetic carbon sequestration pathway of the microalgae.

Waste frozen product harmless resource regeneration method based on microalgae synergistic fermentation

Resumen de: CN120551165A

The invention provides a waste frozen product harmless resource regeneration method based on microalgae synergistic fermentation, and belongs to the technical field of waste frozen product harmless treatment. The preparation process comprises the following steps: pretreatment of waste frozen products; carrying out synergistic fermentation on the pretreated frozen microalgae; and directionally preparing the product. According to the method, in the pretreatment stage, ozone water is adopted for sterilization, citric acid is used for adjusting the pH value to be acidic, synergistic fermentation of bacillus and lactic acid bacteria is combined, harmless treatment is achieved, multi-stage resource utilization is achieved based on microalgae synergistic fermentation, and the additional value is increased.

METHOD AND SYSTEM FOR TREATING ANIMAL PRODUCTS

Resumen de: US2025270148A1

A method for processing animal products, in particular products from poultry farming, includes: a) chemically treating by placing collected waste in contact with an ammonia-based buffer with a pH of at least 8; b) heating the material resulting from step a) in a humid medium to a temperature of at least 70° C.; c) separating the organic matter and inorganic matter in the presence of water from the material resulting from step b), then separated collection of (i) the liquid fraction having the inorganic matter, and (ii) the solid fraction having the organic matter; and d) adding the liquid fraction resulting from step c (ii), having the inorganic matter, in a basin filled with water held in a controlled manner at a setpoint temperature ranging from 20° C. to 42° C., preferably from 28° C. to 35° C., in which a protein-rich plant or bacterium is cultivated, in particular microalgae or cyanobacteria, preferably spirulina.

APPARATUS, SYSTEM, AND METHODS FOR CULTIVATING GREEN MICRO ALGAE (H. PLUVIALIS) AND FOR HARVESTNG ASTAXANTHIN THEREFROM

Resumen de: US2025270486A1

An assembly, methods, and network for farming and culturing green microalgae (Haematococcus pluvialis) are disclosed, comprising: a mechanical support framework; a plurality of cultivation pouches, mechanically coupled to the mechanical support framework, having arrays of cultivation pouches where green microalgae (H. pluvialis) are cultured and harvested; a plurality of light emitting diodes (LEDs), mechanically coupled and supported by the mechanical support framework and arranged in between two of any adjacent arrays of cultivation pouches, operable to provide a predetermined light intensities to each of the cultivation pouches; and an air and gas supply and distribution unit, mechanically coupled and supported by the mechanical support framework, operable to supply predetermined amounts of air and carbon dioxide (CO2) to each of the green microalgae pouches.

OCULAR DELIVERY OF ACTIVE AGENTS VIA MICROALGAE EXTRACELLULAR VESICLES

Resumen de: WO2025176847A1

Provided are compositions containing microalgae extracellular vesicles (MEVs) formulated for administration to the eye for treatment of diseases, disorders, and conditions of the eye, particularly for diseases, disorders, and conditions that involve tissues and cells in the back of the eye, which generally cannot be treated with eyedrops. Upon administration to the eye, the MEVs deliver therapeutics to tissues that include the choroid, retinal pigment epithelium cells, and photoreceptor cells. The compositions contain extracellular vesicles from microalgae (MEVs) that are loaded with bioactive cargo for treating or diagnosing or monitoring a disease, disorder, or condition of the eye or involving the eye. Methods of treatment of diseases, disorders, and conditions of the eye are provided.

MICROALGAE EXTRACELLULAR VESICLE BASED GENE THERAPY VECTORS (MEV-GTVS), THEIR PREPARATION, AND USES THEREOF

Resumen de: WO2025176843A1

Provided are gene therapy vectors designated MEV-GTVs, which are MEVs that contain an ITR-containing plasmid (also referred to as a minigene plasmid) that comprises Inverted Terminal Repeats (ITRs), such as viral ITRs, and nucleic acid encoding a product of interest, and optionally regulatory sequences. The ITRs serve to circularize the minigene plasmid. The plasmids do not contain additional viral components, so that resulting DNA is not encapsulated in a viral capsid or envelop and is not replicated by viral genes. The plasmids can be inserted into bacterial plasmids for propagation.

METHOD FOR EXTRACTING EXOSOMES CONTAINING TARGET ACTIVE INGREDIENTS FROM MICROALGAE

Nº publicación: KR20250127241A 26/08/2025

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