Alerta

薬剤包装装置

Resumen de: WO2021210516A1

The present invention addresses the problem of providing a drug discharge device that can reduce the complexity involved in dispensing a drug into a manual dispensing device.　This drug discharge device comprises: a manual dispensing member 15 provided with a plurality of recesses 20 into which solid drugs are dispensed; a discharge means for discharging the drugs that have been dispensed into the recesses 20, so as to be discharged downstream either directly or with another member being interposed; and a control device for controlling the discharge means. The drug discharge device wherein: the discharge means is capable of individually discharging drugs corresponding to any of the recesses 20; and the control device, on the basis of prescription information including information on the drugs to be provided to one or more patients, allocates the same drug to the recesses 20 in a proximate region, with the discharge means discharging the drugs in a prescribed order.

制御システム及び非一時的な情報記憶媒体

Resumen de: US2024306920A1

0000 A system for analyzing a reflected signal during a laser procedure can include a surgical scope. A first light source emitter can be configurable to emit a first signal having a first (e.g., a non-visible) spectrum. A second light source emitter can be configurable to emit a second signal having a second spectrum (e.g., a visible or infrared (IR) spectrum). Each of the first or the second light source emitters can be coupled to or included within the surgical scope. The system can include an optical sensor configurable to detect and analyze a third signal returned from the surface of an object in response to the emitted second signal. The returned third signal can be analyzed to determine whether a reflected absolute or relative intensity or an absolute or relative spectral signature meets at least one criterion, thereby triggering at least one of: warning a user or adjusting the first signal.

診断方法

Resumen de: WO2021089651A1

The current application relates to personalised nutrition methods, particularly to methods of determining whether a human subject would benefit from taking a urolithin supplement and methods for determining the treatment dose of a urolithin supplement for a human subject. Particularly methods comprising determining the level of urolithin or a urolithin conjugate in a biological fluid, such as a dried whole blood spot sample, a dried plasma spot, a m spot sample or a urine sample The current application also relates to systems for presenting whether a human subject would benefit from taking a urolithin supplement and for presenting the treatment dose of a urolithin supplement for a human subject. The current application also relates to computer implementation of methods of the invention.

薬物投与スキームを決定するように構成された薬物投与システム

Resumen de: WO2021059214A1

In general, systems for administering a drug are provided. In an exemplary embodiment, a drug administration system includes a drug administration device configured to communicate with a computer system and at least one sensor configured to obtain sensor data and communicate the sensor data to the drug administration device. The drug administration device is configured to utilize a first drug dosing scheme when a drug is delivered to a patient, determine a second drug dosing scheme for delivering a drug to the patient dependent on dosing data from the computer system and sensor data collected by the sensor during and/or after the delivery of the first drug according to the first drug dosing scheme, and utilize the second drug dosing scheme when the drug is delivered to the patient.

SYSTEMS AND METHODS FOR PRINTING A CORE FIBER

Resumen de: EP4792842A2

Aspects of the invention include systems and methods for producing hollow fiber structures, and for producing three-dimensional (3D) biological structures from digital files. In some embodiments, the printed fibers comprise living cells.

INTRAORAL SCANNING SYSTEM

Resumen de: EP4792730A2

An intraoral scanning system is disclosed, comprising a hand-held wand having an imaging sensor and a plurality of light sources configured to emit light at different spectral ranges corresponding to different imaging modalities, a display output and one or more processors. The one or more processors are configured to perform a method comprising: processing a plurality of records from the hand-held wand to identify an actionable dental feature from the plurality of records using a machine learning technique, wherein each record of the plurality of records comprises a plurality of images of a patient's dental arch, and wherein each record is taken with a different imaging modality; correlating the plurality of records with a three-dimensional (3D) model of the patient's dental arch; identifying, using the 3D model of the patient's dental arch, a region of the dental arch corresponding to the actionable dental feature on the 3D model of the patient's dental arch; and flagging the actionable dental feature on the 3D model of the patient's dental arch.

BIODEGRADABLE FILM HAVING THREE-DIMENSIONAL ORDERED POROUS STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Resumen de: EP4792841A1

0001 The invention provides a biodegradable membrane with a three-dimensional ordered porous structure, a preparation method therefor and an application thereof. The biodegradable membrane has good mechanical properties, with upper and lower surfaces capable of constructing the same or different ordered porous micro-nano structures, thereby enabling the repair of the same or different tissues. Meanwhile, a degradation time of the corresponding structural layer can be controlled by structural differences and material selection to adapt to a repair cycle of different tissues and improve repair effects. In addition, an intermediate disordered fiber layer is disposed to not only provide a scaffold for tissue engineering with selective permeability but also ensures that the repair of a first ordered layer and a second ordered layer does not interfere with each other, thus expanding the applicability of the scaffold for tissue engineering. The preparation method of the invention adopts a near-field direct-write 3D printing method. By adjusting printing parameters of different structural layers, the structure of each layer can be controlled to give a product the expected performance. The preparation method is simple, convenient to operate, and easy to implement.

DEVICES FOR ESTIMATING REGIONAL METABOLIC RATE OF ORGANS BASED ON HEAT GENERATION AND FOR ESTIMATING REGIONAL BLOOD FLOW(S) FOR THE VOLUME(S) OF TISSUE PERFUSED

Resumen de: EP4792787A1

0001 The present application provides systems that include a controller, and an insertion device with at least one temperatures sensor thereon and a pump coupled to the controller. The insertion device provides temperature measurement(s) at/of a subject's organ to the controller and the controller varies an infusate flow rate to induce temperature changes in at least a portion of the subject's organ and stores the temperature measurements during perfusion induced temperature changes on a memory device. The controller may estimate at least one hemodynamic characteristic of at least a portion of the subject's organ based on the temperature measurements obtained during perfusion induced temperature changes.

HOME MEDICAL DEVICE SYSTEMS AND METHODS FOR THERAPY PRESCRIPTION AND TRACKING, SERVICING AND INVENTORY

Resumen de: EP4793866A2

A therapy entry, modification and reporting system (110) is described. The system comprises: a website configured to display therapy entry, modification and reporting information; and a system hub (120) configured to manage a flow of the information between the website and a plurality of home therapy machines (100) that perform a home therapy on a patient. The website includes: a therapy prescription screen (1000) configured to specify supplies needed at the patient's home or dwelling for operation with one of the home therapy machines (100), a device program screen (1600, 3400) configured to set parameters by which at least one of the home therapy machines (100) operates to perform the home therapy on the patient, and a clinician dashboard screen (1200, 3000) including a list of patients and a notification associated with at least one of the listed patients, the notification indicating whether a predefined treatment condition or alert occurred during the home therapy.

METHOD FOR DESIGNING ORTHODONTIC DEVICE THROUGH CORRECTION OF SET-UP TEETH MODEL

Resumen de: EP4792773A1

The present invention relates to a method for designing an orthodontic appliance using a computer. The method comprises displaying a tooth arrangement image (S01), correcting an arrangement state of teeth in the tooth arrangement image (S02), correcting shapes of teeth in the tooth arrangement image (S03), displaying an orthodontic appliance on a screen according to the corrected tooth arrangement image (S04), and outputting the orthodontic appliance using a 3D printer (S05).

METHOD FOR DESIGNING ORTHODONTIC DEVICE ACCORDING TO PARTIAL DESIGNATION OF TEETH

Resumen de: EP4792772A1

0001 The present invention relates to a method for designing an orthodontic appliance according to partial designation of a tooth using a computer. The method includes: displaying a patient's dentition (S01); setting up all teeth in the dentition and displaying the dentition in a state after orthodontic correction (S02); designating a tooth in the dentition (S03); designating a specific portion of the designated tooth (S04); and inputting a thickness of an orthodontic appliance that contacts the designated specific portion of the designated tooth (S05).

SYSTEMS AND METHODS FOR MICROMANUFACTURING AND BIOPRINTING IN A MICRO GRAVITY ENVIRONMENT THEREOF

Resumen de: WO2025080715A1

The system, methods, and uses of micromanufacturing materials, scaffolds, and living tissues in microgravity environment that is found in space such as Low-Earth-Orbit, on a spacecraft in-transit between celestial bodies, or on other celestial bodies such as the Moon or Mars.

MANAGING CONTAINERS IN A MEDICAL DIAGNOSTIC SYSTEM

Resumen de: EP4793970A2

0001 An example medical diagnostic system includes one or more containers that are usable in a medical diagnostic test. Each container has an identification (ID) tag associated therewith. An ID tag of a container includes memory that is readable and writeable. The memory is for storing information relating to the container. Antennas are configured to communicate wirelessly with ID tags associated with the one or more containers. A control system is configured to store a location of the container based on an identify of the antenna, to select the antenna for communication with the ID tag, and to use the antenna to read at least some of the information from, or to write at least some of the information to, the memory on the ID tag.

MONITORING AND VISUALIZING GAIT OF A USER OF AN ASSISTIVE DEVICE

Resumen de: EP4792733A1

0001 Embodiments disclosed herein provide a mobile device (103) for monitoring and visualizing a gait of a user (101). The mobile device (103) includes a camera (204), an I/O interface (202), a memory (203) comprising an application (104) and a processor (201) connected to the memory. The processor (201) is configured to start a gait session to receive a measurement data from plurality of sensors of the user (101) wearing an assistive device (102), the gait session initializes the measurement data reception from the plurality of sensors. Further, the processor (201) activates the camera to record a video data of the user (101) concurrently receiving the measurement data from the plurality of sensors during the gait session. The processor (201) applies timestamps to frames of the video data of the user (101) with respect to the measurement data based on the initialization signal to obtain time-synchronized gait visualization data (301).

Apparatus and method for localization associated with aortic valve repair using transesophageal echocardiography

Resumen de: US12708457B1

An apparatus for localization associated with aortic valve repair using transesophageal echocardiography, wherein the apparatus includes a probe configured to capture images of an aortic valve pertaining to a subject, a delivery system including a delivery catheter configured for aortic valve repair, and a computing device configured to receive a 3D model representative of the aortic valve, receive an initial set of images from the Probe, wherein the Probe is located within an esophagus of the subject, identify a position of the Probe and the delivery system by identifying anatomical landmarks within the initial set of images and locating the position of the Probe and the delivery system relative to the anatomical landmarks and display the position of the delivery system relative to the 3D model.

신속 붕해 정제를 위한 개질 전분 기반 재료

Resumen de: WO2025124741A1

The instant invention relates to a powder layer for use in 3D binder jetting printing comprising a hydrolyzed and functionalized starch compound. It also relates to a process for 3D binder jetting printing using the same. It also relates to products, in particular solid dosage forms, obtained thereof by 3D binder jetting printing.

便携式无创血糖连续监测的医学检验设备及监测算法

Resumen de: CN122581750A

0001 本发明公开便携式无创血糖连续监测的医学检验设备及监测算法，涉及医学监测技术领域，算法通过物理信号采集层的量子点增强传感器与代谢共振激发器采集血糖相关物理信号，经量子信号处理层处理后，利用智能算法核心中包含时空图卷积模块、代谢动力学建模模块和个性化适配层的时空图卷积神经网络进行信号处理，输出血糖值和置信度，设备集成各关键组件，且有动态校准机制，算法核心将血糖值和置信度输出至校准决策模块，依据置信度判断是否触发校准微，流控系统配合组织液采集与电化学检测实现参数优化，整体设计为便携式结构，便于日常使用，实现精准无创血糖连续监测。

一种上颌第一磨牙拔除术前规划方法及系统

Resumen de: CN122598951A

0001 本申请提供一种上颌第一磨牙拔除术前规划方法及系统；所述上颌第一磨牙拔除术前规划方法包括：基于患者的CBCT数据和口扫数据构建患牙三维模型；基于所述患牙三维模型获得最优分牙深度；根据所述CBCT数据构建有限元模型，以基于所述有限元模型获得拔牙器械的最优用力方向；根据所述患牙三维模型获得各牙块的最优脱位方向；以及，结合所述最优分牙深度、最优用力方向和最优脱位方向评估术中风险等级，以生成风险评估和规划报告。本申请将数字化技术与拔牙手术的临床需求深度融合，显著提升了上颌第一磨牙，尤其是高难度病例拔除术前评估的精准性、预见性和安全性，有助于系统性降低手术并发症，提高手术成功率。

一种用于断奶仔猪肠道发育与功能的综合检测方法

Resumen de: CN122581676A

0001 本发明涉及畜牧养殖与智能检测技术领域，具体公开了一种用于断奶仔猪肠道发育与功能的综合检测方法，包括：采集断奶仔猪粪便与腹壁近红外光谱，融合DNA甲基化标记及近红外荧光纳米传感器，无创定位肠道微损伤区域；采集断奶仔猪不同日龄肠道内容物，构建代谢组时序图谱，融合自适应神经模糊推理系统，对已定位损伤进行急性或慢性病程回溯，区分应激性损伤与发育滞后；本发明通过融合粪便脱落细胞DNA甲基化检测与近红外荧光纳米传感器的腹壁透射光谱分析，无需采集肠道活检组织即可生成三维肠道损伤概率热力图，能够检出常规手段难以发现的早期隐袭性损伤，并可区分原发性损伤与继发性扩散区域，显著降低断奶仔猪肠道病变的漏检率。

基于脑电图自监督图结构提取的抑郁症表征提取方法

Resumen de: CN122599087A

本申请公开了基于脑电图自监督图结构提取的抑郁症表征提取方法，涉及脑电信号处理技术领域，方法包括：提取正常脑电图信号的原始信号、伪幅值异常信号和伪频率异常信号的单通道时序特征作为节点特征；提取正常脑电图信号的原始信号、伪弱连接信号和伪强连接信号的通道间关联特征作为边特征；根据节点特征和边特征构建脑功能网络图结构；利用多层池化提取脑功能网络图结构各层的图级表征；累加各层图级表征得到最终的图表征作为抑郁症表征。本申请通过生成脑电图信号的伪异常信号来构建脑功能网络图结构，进而提取图级特征，能够准确表示脑电图信号的特征，可为分析抑郁症提供真实准确的数据基础。

一种按摩设备的智能控制方法及装置

Resumen de: CN122582004A

本申请提供一种按摩设备的智能控制方法及装置，涉及智能控制技术领域。在本申请中，在按摩设备按照第一按摩模式对目标对象进行按摩的过程中，获取按摩设备在当前时刻作用于目标对象的原始压力信号；对原始压力信号进行第一次信号解耦，得到第一信号分量；基于第一信号分量指示的有效按摩压力，以及与当前时刻相邻的上一时刻的历史压力参考基线，确定当前时刻对应的当前压力参考基线；基于有效按摩压力与当前压力参考基线之间的压力差值，以及预设的压力差值范围，识别目标对象的按摩力度意图，确定按摩设备的目标按摩模式。这样，可以准确且自适应地调整按摩设备的按摩模式，以更好地满足用户的按摩需求。

一种鞍座高度标记确定方法、儿童平衡车以及调节方法

Resumen de: CN122590785A

0001 本申请涉及儿童平衡车技术领域，尤其是涉及一种鞍座高度标记确定方法、儿童平衡车以及调节方法，方法包括基于测试数据确定每个测试身高区间对应的初始理论鞍座高度；获取每个初始理论鞍座高度对应的静态测量数据，并确定多个静态指标和静态指标测量值；对异常理论鞍座高度进行微调，得到对应的修正鞍座高度；基于每个动态测量数据确定多个动态指标和动态指标测量值；将每个动态指标的动态指标测量值与对应的预设动态指标理论值区间相比，对异常修正鞍座高度进行微调，得到每个测试身高区间对应的目标鞍座高度。本申请便于提升不同身高区间的儿童与鞍座高度的匹配精准度，以匹配儿童身体发育特点、促进建立正确骑行姿态。

一种基于3D打印技术的牙齿修复体加工装置及方法

Resumen de: CN122584671A

本发明涉及牙齿修复体3D打印技术领域，具体为一种基于3D打印技术的牙齿修复体加工装置及方法，包括支撑台，还包括：驱动机构，其安装在支撑台上，且升降端上安装升降板；震动机构，其安装在升降板上；晃动机构，其安装在支撑台上，且用于晃动树脂材料；震动机构包括支撑组件、阻尼组件、间隔组件、阻挡组件、承载组件和支撑板；支撑板安装在升降板上且随着升降板升降；支撑组件安装在支撑板上；承载组件安装在支撑组件底部且用于承载打印出的牙齿修复体；本发明使得弹性件一的弹性带动安装板快速上升震动，从而使得承载板底端的牙齿修复体震动，从而将牙齿修复体表面残留的树脂材料抖落，从而避免了树脂材料的残留和浪费。

一种聚乳酸类聚酯纳米片粉末及其制备方法与应用

Resumen de: CN122587245A

一种聚乳酸类聚酯纳米片粉末及其制备方法与应用，涉及高分子材料技术领域，解决了聚乳酸类聚酯粉末的制备技术难以兼顾工艺简洁、设备成本低、形貌可控及避免外源性杂质残留的问题。本发明通过将聚合物加入混合溶剂中，静置，得到聚合物凝胶；向聚合物凝胶中加入溶剂，搅拌得到悬浊液，将悬浊液过滤、干燥得到聚乳酸类聚酯纳米片粉末，可应用于药物缓释载体、医美组织填充材料、3D打印材料领域。本发明实现了聚乳酸类聚酯纳米片状结构的可控制备，显著减少了聚乳酸类聚酯纳米片粉末中单体残留率（0.10%～0.15%）和溶剂残留率（0.01%），进而大幅降低杂质残留风险。

一种肠风黑散碳点方剂及其制备方法与应用

Nº publicación: CN122582187A 18/08/2026

Solicitante:

中国人民解放军总医院第四医学中心

Resumen de: CN122582187A

本发明实施例公开了一种肠风黑散碳点方剂及其制备方法与应用，属于生物制药技术领域。一种肠风黑散碳点方剂的制备方法包括：取等质量的荆芥、枳壳、乱发、槐花、槐角、甘草、刺猬皮，将各单味药材依次经煅烧、粉碎、提取、过滤、浓缩、第一透析纯化后，定容至相同体积，得到单味碳点溶液；单味碳点溶液按体积比2：3：1：1：1：1.5：1.5混合，经超声、第二透析纯化，得到所述肠风黑散碳点方剂。本发明提供的肠风黑散碳点方剂可靶向聚集于烧伤受损肠道组织，对烧伤后肠黏膜损伤表现出突出的修复、保护效果，具备较好的临床应用转化前景。