Alerta

THIOLATED RECOMBINANT BACTERIAL COLLAGEN-LIKE PROTEINS

Resumen de: US20260242426A1

0000 Recombinant bacterial collagen-like protein, preferably with an amino acid sequence that is at least ≥60% identical to the amino acid sequence of SEQ ID NO:1 wherein the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1, wherein the recombinant collagen-like protein is functionalized with at least one thiol group. A bioink comprising the functionalized recombinant bacterial collagen-like protein, at least one solvent and optionally at least one photoinitiator, a process for producing a hydrogel by crosslinking the functionalized recombinant bacterial protein or the bioink as well as the hydrogel obtained therefrom. Furthermore, a scaffold for tissue engineering comprising the hydrogel.

A MICROFLUIDIC DEVICE AND A METHOD OF FORMING THEREOF

Resumen de: US20260242710A1

A method of manufacturing a patient-specific microfluidic device and a patient-specific microfluidic device are provided. The method includes obtaining three-dimensional (3D) information associated with vascular geometry in a region of interest from one or more clinical images associated with a patient, and fabricating the patient-specific microfluidic device using said 3D information. The patient-specific microfluidic device includes a flow channel having a geometry that substantially corresponds to the vascular geometry in the region of interest.

AUTOMATIC PRESSURE ULCER MEASUREMENT

Resumen de: US20260245231A1

Methods and systems for imaging and analysis are described. Accurate pressure ulcer measurement is critical in assessing the effectiveness of treatment. However, the traditional measuring process is subjective. Each health care provider may measure the same wound differently, especially related to the depth of the wound. Even the same health care provider may obtain inconsistent measurements when measuring the same wound at different times. Also, the measuring process requires frequent contact with the wound, which increases risk of contamination or infection and can be uncomfortable for the patient. The present application describes a new automatic pressure ulcer monitoring system (PrUMS), which uses a tablet connected to a 3D scanner, to provide an objective, consistent, non-contact measurement method. The present disclosure combines color segmentation on 2D images and 3D surface gradients to automatically segment the wound region for advanced wound measurements.

METHODS AND SYSTEMS FOR CONTROLLING OXYGEN DELIVERY IN A FLOW THERAPY APPARATUS

Resumen de: AU2026210822A1

The present disclosure provides for a control system for a flow therapy apparatus. The control system can control delivery of a fraction of delivered oxygen (FdO2) to a patient. The control system can maintain the FdO2 at a target level during a therapy session. The control system can automatically control an oxygen inlet valve in order to control the flow of oxygen to the patient. ul u l

SYSTEM FOR MONITORING AT LEAST ONE PARAMETER REPRESENTATIVE OF A DECOMPENSATION OF A CARDIAC FAILURE BY MEANS OF A SUBCUTANEOUS IMPLANT

Resumen de: US20260240434A1

A system for monitoring at least one parameter representative of an episode of decompensation, the monitoring system comprising at least one subcutaneous implant, the subcutaneous implant comprising at least one electrocardiograph and one accelerometer configured to collect information relating at least to the functioning of the heart of the living being, the monitoring system also comprising a computer server and a communication relay configured to allow at least the exchange of information collected by the subcutaneous implant with the computer server, the computer server being configured to calculate changes in at least one parameter, from among hemodynamic and/or respiratory and/or electrophysiological parameters, on the basis of the data collected by at least the accelerometer and the electrocardiograph.

WEARABLE SENSOR AND SYSTEM THEREOF FOR BLOOD PRESSURE MONITORING

Resumen de: US20260245717A1

A blood pressure monitoring system includes a wearable tracker configured to be worn by a user. The wearable tracker includes a ferroelectret film-based sensor configured to obtain a ballistocardiogram signal, electrodes configured to obtain an electrocardiogram signal, and a processor configured to process the ballistocardiogram signal and the electrocardiogram signal to estimate the user's blood pressure continuously. In some embodiments, the processor further calculates heart rate variability for use in estimating blood pressure. The ferroelectret film-based sensor may detect mechanical vibrations associated with heartbeat and breathing. The system may further include a communication module for transmitting physiological data or estimated blood pressure to a remote device.

SPEKTRALAUFZEICHNUNG WÄHREND DER DAUERSTRICH-LASEREMISSION

Resumen de: DE112024004598T5

Ein System zur Spektralerfassung während eines medizinischen in-vivo-Eingriffs kann einen Prozessor und einen Speicher umfassen, auf dem Befehle gespeichert sind, die den Prozessor veranlassen, ein Beleuchtungssignal von einer Beleuchtungsquelle in Richtung eines in-vivo-Ziels auszusenden, ein erstes Rücksignal vom in-vivo-Ziel als Reaktion auf das Beleuchtungssignal zu erfassen und ein Lasersignal von einer Dauerstrichlaserquelle in Richtung des in-vivo-Ziels auszusenden. Die Befehle können den Prozessor ferner veranlassen, ein zweites Rücksignal vom In-vivo-Ziel zu erfassen, eine Differenz zwischen dem ersten Rücksignal und dem zweiten Rücksignal zu bestimmen und eine Maßnahme zu ergreifen, die zumindest teilweise auf der bestimmten Differenz basiert.

SYSTEMS AND METHODS FOR RESOLVING AN ERROR CONDITION OF A MEDICAL DEVICE

Resumen de: US20260244472A1

0000 A system and method for resolving an error condition of a medical device includes the medical device, a mobile device, and a host computer. The medical device generates a machine readable code, the machine readable code is read by the mobile device, and the remote computer hosts a uniform resource locator (URL) associated with the machine readable code such that the mobile device can access the URL.

APPARATUS AND METHOD FOR ARRAY POSITIONING

Resumen de: US20260241188A1

A method includes generating, from an electronic 3-dimensional map indicating placement locations of a plurality of electrode arrays, an electronic 2-dimensional map indicating placement locations of the plurality of electrode arrays relative to each other in 2-dimensional space. The electronic 3-dimensional map is associated with a surface area of at least a portion of a body of a patient. The electronic 3-dimensional map indicating the placement locations of the plurality of electrode arrays can be generated based on at least one medical image.

3D BIOPRINTING OF STRUCTURE CELL AGGREGATES AND ORGANOIDS

Resumen de: US20260241635A1

0000 Additive manufacturing methods, additive manufacturing systems, and products thereof are provided. The method comprises depositing a bioink into a support material based on a first computer model of an object, thereby forming a first portion of an object in the support material. The bioink comprises cells. The method comprises depositing a structure material into the support material based on the first computer model of an object, thereby forming a first portion of a scaffold for the object. The structure material is different from the bioink and the structure material comprises a polymer. The method comprises repeating the depositing of the bioink and the structure material as necessary to additively form the object and the scaffold within the object.

ERKENNUNG VON GERÄTESTÖRUNGEN BEI MEDIZINISCHEN GERÄTEN

Resumen de: DE112024004308T5

Ein System und ein Verfahren zur automatischen Erkennung von Instrumentenfehlfunktionen in einer Probenentnahmevorrichtung während eines medizinischen Eingriffs können das Erfassen einer Folge von Ultraschallbildern eines Zielgebiets des medizinischen Eingriffs über einen Wandler der medizinischen Vorrichtung umfassen. Das System oder Verfahren kann ferner das Erkennen eines Instruments in der Folge von Ultraschallbildern umfassen, das sich von der medizinischen Vorrichtung aus erstreckt und sich innerhalb des Sichtfelds des Wandlers befindet. Für jedes Ultraschallbild der Sequenz von Ultraschallbildern, das das aus dem medizinischen Gerät herausragende Instrument enthält, kann eine Eigenschaft des aus dem medizinischen Gerät herausragenden Instruments bestimmt werden. Das System oder Verfahren kann ferner das Erzeugen eines Warnsignals umfassen, das auf der Eigenschaft des aus dem medizinischen Gerät herausragenden Instruments basiert, die einen Schwellenwert überschreitet, wobei das Warnsignal eine potenzielle Anomalie des aus dem medizinischen Gerät herausragenden Instruments anzeigt.

CLOSED LOOP OXYGEN CONTROL

Resumen de: US20260241124A1

The present disclosure provides for a flow therapy apparatus that can implement one or more closed loop control systems to control the flow of gases of a flow therapy apparatus. The flow therapy apparatus can monitor blood oxygen saturation (SpO2) of a patient and control the fraction of oxygen delivered to the patient (FdO2). The flow therapy apparatus can automatically adjust the FdO2 in order to achieve a targeted SpO2 value for the patient.

A METHOD FOR PROCESSING IMAGE, AN ELECTRONIC APPARATUS AND A COMPUTER READABLE STORAGE MEDIUM

Resumen de: US20260245201A1

0000 A method for processing an image, an electronic apparatus performing the same, and a computer readable storage medium storing the same may be provided. The method for processing an image includes receiving at least one intraoral image, aligning the at least one intraoral image to a occlusal plane, setting an inner surface of a splint based on the at least one aligned intraoral image, setting an outline of the splint based on the at least one intraoral image, setting an outer surface of the splint based on the outline, and displaying the at least one intraoral image, to which the splint is applied, generated based on the outer surface.

A METHOD FOR PROCESSING IMAGE, AN ELECTRONIC APPARATUS AND A COMPUTER READABLE STORAGE MEDIUM

Resumen de: US20260245202A1

0000 A method for processing an image, an electronic apparatus performing the same, and a computer readable storage medium storing the same may be provided. The method for processing an image includes receiving an intraoral image including maxillary scan data and mandibular scan data; calculating an occlusal distance to antagonist of the intraoral image based on an occlusal state of the intraoral image; and adjusting the occlusal distance to antagonist corresponding to the occlusal state of the intraoral image based on the calculating.

生体組織を再生させるための３次元スキャフォールド

Resumen de: WO2025037005A1

This disclosure pertains to the field of tissue regeneration to repair damaged tissue and in particular brain tissue. The scaffold (1) of the present disclosure comprises a set of horizontal layers (11, 12, 13, 14), each layer extending in a horizontal plane orthogonal to the vertical direction (Z), each layer (11, 12, 13, 14) comprising a plurality of openings (15), each opening (15) of one layer (11, 12, 13, 14) being connected to one opening (15) of the directly adjacent layer (11, 12, 13, 14) by at least one first pillar (16) extending along the vertical direction (Z). Thus, the scaffold (1) of the present disclosure is designed to promote a cell growth radially along each layer (11, 12, 13, 14) to reconstruct the grey matter portion of the damaged area and the white matter along the vertical pillars (16) extending through the different layer (11, 12, 13, 14).

SYSTEMS AND APPARATUSES FOR MEDICAL AGENT ADMINISTRATION

Resumen de: AU2026210733A1

A medical agent administration device may comprise a main body including a central region and a peripheral region. The peripheral region may have a plurality of petal members extending outwardly from the central region. The device may further comprise at least one coupling on a first face of the central region. The device may further comprise at least one sharp bearing body on an opposing face of the central region. Each of the at least one sharp bearing body may be in fluid communication with a respective one of the at least one coupling. ul u l

Configuring Applications Based On A User'S Wakefulness State

Resumen de: US20260240490A1

0000 Techniques for configuring one or more applications based on a detected wakefulness state of a user are disclosed. A system trains and applies a machine learning model to wakefulness data to compute a wakefulness state of a user. The system obtains the wakefulness data from wearable devices worn by the user and environmental devices in a user's environment. The system configures applications and/or devices based on the computed wakefulness state of the user. The system configures the ability of devices or applications to generate visual, audible, or tactile notifications in response to determining that a user is awake or asleep.

REAL-TIME MEAL DETECTION BASED ON SENSOR GLUCOSE AND ESTIMATED PLASMA INSULIN LEVELS

Resumen de: US20260241102A1

0000 Disclosed herein are techniques related to automatic real-time meal detection. In some embodiments, the techniques involve obtaining a plurality of glucose concentration values and a plurality of plasma insulin concentration values. At least one of the plurality of glucose concentration values is obtained within a time range of a determination of a respective plasma insulin concentration value of the plurality of plasma insulin concentration values. The techniques further involve generating an output based on applying a meal detection model to the plurality of glucose concentration values and the plurality of plasma insulin concentration values and determining, based on the output, that a glucose concentration value of the plurality of glucose concentration values corresponds to an ongoing glycemic response to a meal.

System and Method for Detecting Presence of Illness Symptoms

Resumen de: US20260240485A1

0000 A system and method for collecting symptomatic data to screen for a targeted disease. Testing hardware incorporates a plurality of testing units with corresponding indicators that can be altered to indicate whether a symptom is present or not. The resulting data from the testing use can then be analyzed to determine the likelihood of presence of a disease.

ACTIVITY PREDICTION

Resumen de: US20260244938A1

Systems and techniques for training an activity prediction model and for performing activity prediction utilizing the activity prediction model are described herein. An activity prediction model may be trained by training potential activity prediction models using machine learning based on an input dataset including activity of an individual from a training phase, ground truth dataset and different hyperparameters, performing hyperparameter optimization, and optimizing the potential activity prediction models for accuracy or minimizing loss. Thereafter, the activity prediction model may be utilized by passing an execution dataset including a set of sensor data associated with activity of an individual from an execution phase to generate an activity prediction which may be indicative of a current or future activity of the individual.

SYSTEMS AND METHODS FOR MAGNETIC RESONANCE IMAGING CALIBRATION

Resumen de: US20260245382A1

0000 A method can include determining a first association between a first magnetic resonance imaging (MRI) characterization and a first histological characterization obtained from a first reference sample of a patient. The method can include determining a second association between a second MRI characterization and a second histological characterization obtained from a second reference sample of the patient. The method can include obtaining a third MRI characterization of a region of interest (ROI) from an MRI scan of the patient. The method can include determining a third histological characterization for the ROI using the third MRI characterization and at least one of the first association or the second association.

ORTHODONTIC APPLIANCE SYSTEMS AND METHODS OF MAKING SAME

Resumen de: US20260240625A1

0000 An orthodontic appliance system for orthodontic treatment of teeth. The system includes a template with a cavity. An attachment is removably received in the receptacle and has a surface including a bonding surface. A method of manufacturing includes constructing a scaffold assembly including a base and placing a template in contact with the scaffold assembly. The method includes inserting the attachment into the receptacle. During separating, the attachment remains coupled to the template in the receptacle. A method of manufacturing includes providing a mold of the patient's teeth. The mold including at least one projection and a through-passage. The method includes placing a container of dental composite in fluid communication with the through-passage, placing a template over the at least one projection, injecting dental composite from the container through the through-passage and into the receptacle, and removing the template from the at least one projection with the filled receptacle.

A SYSTEM AND METHOD FOR ENHANCING PROSTHETIC PRECISION

Resumen de: WO2026172241A1

The present invention relates to a system (100) and method for enhancing prosthetic precision by utilizing advanced computer vision integration for intuitive control of artificial limbs. The system (100) comprises a set of hardware components, at least one actuator motor (102), at least one camera (103), at least one processor (104). The set of hardware components include 3D printed structures (101) which are controlled by the actuator motor (102). The camera (103) is configured to capture one or more images or videos of a surrounding and the images or videos are transmitted to the processor. The processor (104) analyzes the images or videos to detect one or more objects in the images or videos via one or more machine learning protocols. Further the processor (104) sends a signal to the actuator motor (102) and 3D printed structures for grasping the concerned object form the one or more objects. The processor (104) is able to dynamically switch between at least four grasp setups (wrist, with palm grip pronated wrist, with palm grip, tripod grip and pinch grip) depending on the objects detected and a set of user preferences.

Customized prosthesis and method of manufacturing same

Resumen de: KR20260125191A

본 발명은 3D 스캐닝을 활용한 맞춤형 실리콘 보형물 제조 시스템으로, 개인별 신체 형상을 정밀하게 측정하고 최적화된 맞춤형 보형물을 제작하는 기술이다. 실리콘 3D 프린팅 및 후가공을 통해 신속하고 효율적으로 보형물을 제공한다.

SYSTEMS AND METHODS OF MONITORING WEAR COMPLIANCE OF A PATIENT WEARING AN AMBULATORY MEDICAL DEVICE

Nº publicación: EP4792873A2 19/08/2026

Solicitante:

ZOLL MEDICAL CORP [US]
ZOLL Medical Corporation

Resumen de: EP4792873A2

0001 Devices, systems, and methods for providing patient wear compliance information are provided. For example, a medical device includes a plurality of electrodes configured to be continuously coupled externally to a patient and to monitor electrical activity on the skin of the patient. The system also includes at least one motion sensor configured to generate a motion signal based upon movement of the patient. The system further includes a processor configured to receive an electrical signal based on the monitored electrical activity, record a wear onset event based on the electrical signal and the motion signal, record a wear offset event based on one or more of the electrical signal and the motion signal indicating that the patient is not wearing the medical device, and output a graphical representation including information regarding the patient's wear compliance based on the recorded wear onset event and the recorded wear offset event.