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528
resultados
Última actualización
31/10/2026 [07:27:00]
Resultados 475 a 500 de 528
Resumen de: WO2026205644A1
The present disclosure relates to a manufacturing method for the mass production and recycling of variable-stiffness intravenous needles of various sizes that become softened by body temperature, the method comprising the steps of: preparing a mold, which is manufactured by 3D printing and has a plurality of elongated channels aligned therein, and a plurality of elongated rods, which can be coaxially arranged in the respective channels; applying a material having variable stiffness according to ambient temperature to the mold so as to encompass each of the rods in the channels; curing the material, and removing the mold and the rods so as to leave a plurality of hollow body members; and forming coating members having biocompatibility so as to cover the respective outer surfaces of the body members, thereby leaving a plurality of variable-stiffness intravenous needles.
Resumen de: WO2026207469A1
Systems and methods for three-dimensional localization of an interventional device within a magnetic resonance imaging (MRI) system are disclosed. The method includes acquiring a baseline MR signal dataset of a target region and a subsequent dataset of the region following introduction of the interventional device using a hybrid encoding pulse sequence. The hybrid sequence applies spatiotemporal encoding in a first plane and Fourier encoding along an orthogonal axis to acquire highly undersampled projection data. A difference dataset is generated by mathematically evaluating the subsequent dataset against the baseline. A processing module determines the precise 3D spatial location of the interventional device by analyzing localized signal anomalies within the difference dataset. The approach circumvents fully sampled Cartesian k-space acquisitions, enabling rapid, intra-procedural tracking of magnetic and non-magnetic devices for manual or robotic guidance across diverse MRI environments, including, but not limited to, open, low-field, and single-sided systems.
Resumen de: WO2026202089A1
A computer-implemented method for determining a tooth implant and an associated surgical guide is described, wherein the method comprises: determining at least one tooth implant model or one or more parameters defining at least one tooth implant model using an implant planning engine, the at least one tooth implant model being associated with an implant orientation and an implant position, the implant planning engine being configured to receive 3D virtual patient data including 3D representations of anatomical structures within a vicinity of the implant position, and to determine the at least one tooth implant model or the one or more parameters defining the at least one tooth implant model based on clinical constraints associated with the anatomical structures within the vicinity of the implant position; determining an implant sleeve model based on the tooth implant model or the one or more parameters defining the tooth implant model; and, determining a surgical guide model based on the 3D virtual patient data and the implant sleeve model, the determining including forming a dental template model based on at least part of the 3D virtual patient data and forming the implant sleeve model in the dental template model so that the implant sleeve model is positioned at the implant position and so that the orientation of the implant sleeve model is parallel to the implant orientation associated with the tooth implant model.
Resumen de: US20260294637A1
Systems and methods include a component of a bone implant that includes a patient specific bone contacting surface and, optionally, at least one protrusion adjacent to or extending from the patient specific bone contacting surface. The at least one protrusion is configured for engaging a bone preparation in the bone. To prepare the bone for receiving the component, one or more cutting tool templates may be used. The one or more cutting tool templates may be fabricated to have a patient specific bone contacting surface that engages the bone that is to receive the implant component. A cutting tool is engaged in one or more of one or more slots defined by the cutting tool template(s) to remove surface portions of the bone to create the bone preparation for engaging the protrusion. The patient specific bone contacting surface of the component engages the bone.
Resumen de: WO2026202090A1
The disclosure relates methods and systems for automated planning of a tooth implant in a dento-maxillofacial complex, the method comprising: determining a tooth implant or one or more implant parameters defining a tooth implant using an implant planning engine, the tooth implant being associated with an implant orientation and an implant position in the dentition, the planning model being configured to receive 3D representations of dental objects and, optionally, tissue, of the dentition and to determine the tooth implant or the one or more implant parameters defining a tooth implant based on clinical constraints associated with the position of the tooth implant and the dental objects in the dentition; and, displaying the tooth implant and, optionally, at least part of the 3D representations of dental objects and a user interface UI associated with the displayed tooth implant, wherein the UI is configured receiving user input for modifying one or more modifying the one or more implant parameters and/or the one or more clinical constraints.
Resumen de: WO2026206879A1
A method for making an intestinal tissue model includes depositing a decellularized small intestine submucosa-norbornene (dSIS-NB) hydrogel within a sacrificial hydrogel intestine mold having negative crypts-villi structures formed thereon, and dissolving the sacrificial hydrogel intestine mold to thereby generate intestinal tissue model having positive crypts-villi structures formed thereon.
Resumen de: WO2026207112A1
Various embodiments include a method of using information from medical electrodes positioned in a patient's heart to identify and display arrhythmia localization. The method may include obtaining electrical signals and location information from electrodes positioned within the patient's heart, generating a patient-specific 3D heart model, generating a patient-specific electrical conduction map identifying arrhythmia initiation site localization, displaying the 3D localization for physician use, and conducting a cardiac ablation procedure using the displayed localization to identify ablation locations. In some embodiments, the medical electrodes may be electrodes on electrophysiology catheters temporarily positioned with the heart. In some embodiments, the medical electrodes may be electrodes of an implanted cardiac defibrillator (ICD) permanently positioned in the heart.
Resumen de: WO2026201935A1
A computer-implemented method for creating a digital model is provided. The method comprises obtaining a first set of scan data indicative of a temporary prosthetic structure (33) arranged on a dental implant embedded in a jaw of a patient. The method comprises obtaining a second set of scan data indicative of the temporary prosthetic structure arranged on a scan body (1) comprising indica (3) indicative of a mounting geometry of the dental implant. The second set of scan data includes a soft tissue emergence profile (31) of the temporary prosthetic structure and the indica. The method comprises selecting a third set of scan data indicative of at least the mounting geometry of the scan body from a database, based on the indica. The method comprises generating a first 3D- model (200) of the temporary prosthetic structure and surrounding dentition, by aligning the first set of scan data, the second set of scan data and the third set of data.
Resumen de: WO2026203551A1
Problem To provide a pad in which is formed a large space for retaining excrement such as urine in the pad, and which makes it possible to prevent excrement that could not be absorbed by an absorbent body from leaking to the outside past a three-dimensional gathering. Solution A pad provided with a liquid-permeable top sheet, a liquid-impermeable back sheet, and an absorbent body between the top sheet and the back sheet, wherein: three-dimensional gatherings that extend in the front-rear direction are fixed at both side parts of the top sheet in the width direction; the absorbent body is formed with a high-stiffness region and a low-stiffness region that is more easily deformable than the high-stiffness region; the low-stiffness region is provided surrounding the outer periphery of the high-stiffness region; and the thickness of the low-stiffness region is greater than the thickness of the high-stiffness region.
Resumen de: WO2026203552A1
Problem To provide a pad that keeps soft stool that travels along fold lines in the pad from passing through base parts of three-dimensional gathers and leaking to the outside from respective side parts of the pad. Solution According to the present invention, a liquid-permeable second sheet that has a greater width in the left-right direction than a top sheet is provided between the top sheet and an absorption body, base parts of three-dimensional gathers that extend in the front-rear direction are fixed to respective side parts in the left-right direction of the second sheet, the absorption body and the side parts in the left-right direction of the second sheet extend further in the left-right direction than the base parts, and first embossing regions are formed at respective side parts of the base parts at fold parts of the second sheet such that the length in the front-rear direction of the first embossing regions is longer than the length of the fold parts.
Resumen de: WO2026206499A1
The present disclosure describes an analyte monitoring system that establishes backup or alternative communication channels that may be used when certain components or connections in the analyte monitoring system become unavailable. The analyte monitoring system may form direct connections between components of the analyte monitoring system and/or select replacement devices when certain components or connections become unavailable.
Resumen de: WO2026206573A1
Described herein is a wearable sensing system that acquires (S)eismocardiography, (P)hotoplethysmography, (I)mpedance pneumography and cardiography, surface (R)espiratory mechanomyography and electromyography, and (E)lectrocardiography signals for monitoring ventilation, cardiovascular dynamics, and respiratory muscle activity.
Resumen de: US20260301909A1
0000 A medical device is configured to identify, in particular to identify the presence of, and/or classify, a medical item. The medical device includes an excitation unit configured to excite a medical item with at least one excitation so that the medical item vibrates. A detection unit detects a sound emission from the excited medical item. An evaluation unit identifies and/or classifies the medical item by analyzing the sound emission, preferably to identify whether the medical item corresponds to at least one predetermined medical item.
Resumen de: WO2026207353A1
Systems, devices, and methods for power management and/or for synchronous advertising-based communication in an analyte monitoring environment are set forth. Information pertaining to clock accuracy is exchanged between a receiver device and an on-body device. The system is configured to make power management decisions based on the clock accuracy information. Avoidance of extended listening windows can provide power savings through prevention or minimization of communication with receiver devices having relatively low clock accuracies. Wireless transmission and reception between devices in an analyte monitoring system in accordance with a synchronous advertising-based protocol are set forth. Advertisements are made by an on-body device and responses are transmitted back from receiver devices. The protocol is highly adaptable for power management. Supplementary information request techniques using synchronous advertising-based protocols and/or secondary channels are set forth. Many variations are set forth.
Resumen de: WO2026199073A1
A portable pupillometer comprising a light stimulus configured to illuminate at least the pupil of an eye to induce a pupillary reflex is provided. A camera is configured to capture a first pupillary baseline image and one or more second images when the pupillometer is directed at a subject's pupil, wherein the first pupillary baseline image is captured prior to pupillary reflex and the second images are captured following activation of the light stimulus. A processor is configured to process the first pupillary baseline image and the second images and determine: a pupillary reflex characteristic based on a difference between one of the second images and the first pupillary baseline image; and a pupil size based on the first pupillary baseline image. The processor activates a first indicator to provide a signal that correlates with pupil size, and a second indicator to provide a signal that correlates with the pupillary reflex characteristic.
Resumen de: WO2026207365A1
In some embodiments, a method includes receiving a certificate request from a user device associated with an analyte sensor. The method also includes, responsive to the receiving, determining a current capacity of a server system, where the current capacity is selected from: a first level, a second level indicative of less capacity than the first level, and a third level indicative of less capacity than the second level. The method also includes, responsive to a determination that the current capacity corresponds to the third level, initiating deferred processing of the certificate request. The method also includes, responsive to a determination that the current capacity corresponds to the second level, conditionally processing the certificate request based on a wait time associated with the certificate request. The method also includes, responsive to a determination that the current capacity corresponds to the first level, processing the certificate request.
Resumen de: WO2026207060A1
Presented herein are systems and methods of classifying risk for bladder cancer. A computing system can receive a plurality of MRI images from an MRI scanner. The computing system can identify a first ROI and a second ROI. The computing system can determine a plurality of features based on the first ROI. The computing system can determine a plurality of metrics based on the second ROI. The computing system can generate a classification of the first subject based on the plurality of features and the plurality of metrics. The computing system can provide an output based on the classification.
Resumen de: WO2026202955A1
A temple mounted wearable device configured to monitor a set of health attributes associated with a user is disclosed The wearable device includes a housing unit adapted to conform to a temple region of the user, with an aperture positioned over a superficial temporal artery, and a computing unit disposed within the housing unit. The computing unit comprises at least one photoplethysmography (PPG) sensor and one inertial measurement unit (IMU) sensor configured to receive physiological data from the temple region. A processor determines a motion-correction status and generates enhanced PPG data when motion correction is required. Further, blood-flow indicators are extracted from at least one of the PPG data and the enhanced PPG data to generate health metrics associated with the user. The temple mounted wearable device communicates with a user device and remote computing resources to monitor health attributes in real-time and determine a health state of the user.
Resumen de: WO2026205738A1
Disclosed are an electronic device for providing health information related to hemoglobin measurement and an operating method thereof. The electronic device may acquire a skin temperature of a user and acquire a nail image of the user by means of a camera. The electronic device may determine a hemoglobin index on the basis of the skin temperature and the nail image, and display a user interface related to the hemoglobin index or health information by means of a display. The electronic device may determine a hemoglobin index on the basis of the nail image, and correct the hemoglobin index on the basis of the difference between a designated skin temperature and the obtained skin temperature. The electronic device may generate a corrected nail image from the nail image on the basis of the obtained skin temperature, and determine a hemoglobin index on the basis of the corrected nail image. Various other embodiments identified by the present document are possible.
Resumen de: WO2026206911A1
Tissue imaging systems, instruments, and methods using fiducial geometry-based displacement determination are provided. One embodiment is a method of determining a fiducial position in a tissue imaging system including: receiving image data representing a fiducial having a predetermined geometry; evaluating a plurality of one-dimensional row segments associated with the image data to generate a plurality of corresponding row-based fiducial position estimates; adjusting one or more of the plurality of row-based fiducial position estimates based on the predetermined geometry; and combining the adjusted fiducial position estimates to determine the fiducial position.
Resumen de: US20260295258A1
The present disclosure relates dynamic closed-loop neuromodulation techniques to induce an externally powered electrical cortical stimulation (XCS) configured for various applications by leveraging real-time neural data of a subject. The neural data may be collected by one or more neuromodulation devices, placed epidurally through surgical implantation into a skull. A brain state may be estimated by processing the neural data via analytical techniques. Based on the predicted brain state, a set of stimulation parameters, associated with the XCS for a cortical region, may be determined. This determination may rely on a state transition model, configured to learn how brain transitions from one brain state to another based on the ongoing neural activity. The brain responses to applied XCS may be monitored from the neural data collected in real-time. Based on the monitoring, one or more stimulation parameters may be dynamically adjusted for each XCS in a closed loop.
Resumen de: WO2026199685A1
Provided are a bioprinted heart valve fibrosis disease model, a preparation method therefor, and use thereof. The method comprises the following steps: using a hydrogel containing valve cells as a printing material, printing by means of digital light processing (DLP) technology to obtain a valve model, wherein the digital light processing technology comprises importing design drawings of different grayscales into a digital light processing printing device, and after printing, culturing to obtain bioprinted heart valve fibrosis disease models with different stiffnesses. According to the method, by means of regulating DLP printing parameters, adjusting the stiffness of an extracellular matrix, controlling the degree of fibrosis of various mechanically responsive cells such as fibroblasts, and simulating different fibrotic states, the effect of the in vivo environment on valve tissue can be better simulated.
Resumen de: ES3080098T3
Se describen sistemas y métodos de monitorización de analitos para calibrar un sensor de analitos mediante una o más mediciones de referencia. Estos sistemas y métodos pueden incluir el uso de una función de conversión y datos del primer sensor para calcular el nivel del primer analito, la ponderación de una primera medición de referencia del analito (RM1) y una o más mediciones de referencia previas según una función de coste medio ponderado, la actualización de la función de conversión utilizando la RM1 ponderada y las mediciones de referencia previas ponderadas como puntos de calibración, y el uso de la función de conversión actualizada y datos del segundo sensor para calcular el nivel del segundo analito. En algunos aspectos, los sistemas y métodos pueden incluir la actualización de uno o más parámetros de retardo utilizados para calcular los niveles del analito del sensor. (Traducción automática con Google Translate, sin valor legal)
Resumen de: WO2026207476A1
Provided herein are methods and devices for diagnosing peripheral artery disease (PAD) using computed tomography angiography (CTA) images. The method involves obtaining at least one CTA image of the patient's vascular system and inputting this image into a trained machine learning model. The model analyzes the image to generate groups of images that highlight vascular abnormalities, including segmented and annotated images. These generated images are then matched to reference images with known characteristics associated with PAD. Based on this analysis, a diagnosis is confirmed, indicating the presence and severity of PAD. Additionally, a comprehensive report is generated, detailing the diagnosis, severity of the condition, and recommendations for treatment options. This approach enhances diagnostic accuracy and efficiency, facilitating timely clinical decision-making for patients with PAD.
Nº publicación: WO2026201743A1 01/10/2026
Solicitante:
LUXINERGY GMBH [AT]
LUXINERGY GMBH
Resumen de: WO2026201743A1
The present invention relates to a resin composition comprising at least one methacrylate compound having at least two methacryl functional groups, at least one thiol compound having at least two thiol functional groups and at least one methallyl compound having at least two methallyl functional groups. The present invention further relates to a printing method, a dental product obtainable by the printing method, and a method of treating a dental product.
BOPI
Sede Electrónica
