Alerta

MOTION-TRACKED IMMERSIVE FUNCTIONAL POSITRON EMISSION TOMOGRAPHY

Resumen de: US20260301947A1

0000 Presented herein are directed to systems and methods for detecting conditions in subjects provided with stimuli. A computing system may send, to a headset situated on a head of a first subject in an upright posture, an instruction for the headset to present a stimuli to direct the subject to perform a task. The computing system may receive, via a tomography scanner arranged about the head of the first subject, a dataset defining a first plurality of tomograms of a first nervous system of the first subject. The computing system may obtain, via a sensor, a first signal associated with a first physiological function of the first subject over the time period. The computing system may determine, from the plurality of conditions, a condition associated with the first nervous system of the first subject based on applying a model to the first plurality of tomograms and the first signal.

HEART VALVE LEAFLET MODELLING

Resumen de: US20260294383A1

Proposed concepts thus aim to provide schemes, solutions, concept, designs, methods and systems pertaining to representing a predicted length of a heart valve leaflet. This can be achieved by obtaining both a 3D model representative of the geometry of a heart valve leaflet and a predicted length of the heart valve leaflet. The 3D model can then be adapted based on the predicted length to generate an adapted 3D model representing an extension of the heart valve leaflet to the predicted length.

MEALTIME DELIVERY OF CORRECTION BOLUSES

Resumen de: US20260295161A1

Disclosed herein are techniques related to delivery of correction boluses. In some embodiments, the techniques involve obtaining data indicative of an ongoing glycemic response to a meal. The data includes glucose concentration measurements evaluated in combination with one or more insulin concentration values. The techniques further include causing delivery of one or more correction doses to at least partially counteract the ongoing glycemic response to the meal. The one or more correction doses are delivered instead of or in addition to a meal bolus delivered for the meal.

ARTIFICIAL-INTELLIGENCE-BASED DEVICE AND METHOD FOR EVALUATING CARDIAC STRAIN THROUGH ELECTROCARDIOGRAPHY

Resumen de: US20260294314A1

0000 Embodiments provide an artificial-intelligence-based device and method for evaluating cardiac strain through electrocardiography, the device comprising: an acquisition unit for acquiring electrocardiography data of a subject; an ECG encoder which inputs with the electrocardiography data so as to extract an ECG embedding vector including feature information of the electrocardiography data; and a cardiac strain task processing unit which inputs with the ECG embedding vector so as to include and generate cardiac strain information about one or more task items. Since the electrocardiography data is input into an artificial-intelligence neural network so as to evaluate the degree of cardiac strain, various cardiac strain can be measured and a consistent quantitative assessment can be performed at a low cost.

DUAL-MODE MOBILE WI-FI OTOSCOPE SYSTEM AND METHODS

Resumen de: US20260301975A1

0000 A method for merging imaging data into a telemedicine session is provided. The method includes initiating a telemedicine session on a host device and determining whether a network connection is available between an otoscope and the host device for providing imaging data. The otoscope is configured to generate a direct connection for providing the imaging data. Based on availability of the network connection, a connection is established between the host device and the otoscope via either the network connection or the direct connection. Imaging data generated by the otoscope, including a video stream and/or one or more images, is shared from the host device during the telemedicine session.

Dental Appliance for Treatment of Bruxism And Sleep Apnea

Resumen de: US20260294672A1

0000 A dental appliance is disclosed. The appliance may include an arcuate base shaped to extend along at least a portion of an upper dental arch of a patient and match with a custom fit at least certain maxillary teeth of the patient. The appliance may further include a tongue-retention feature. The tongue-retention feature may connect to the arcuate base and comprise a palatal portion and a sublingual portion. The sublingual portion may cooperate with the palatal portion to form a cavity shaped to receive an anterior portion of a tongue of the patient therewithin. The palatal portion may have an exterior surface custom-formed to match at least a portion of a hard palate of the patient.

SYSTEM AND METHOD FOR MODELING NEUROLOGICAL ACTIVITY

Resumen de: US20260294322A1

0000 A system for modeling neurological activity includes a computer having one or more processors, one or more computer-readable tangible storage devices, and program instructions stored on at least one of the one or more storage devices. The program instructions are configured to receive electroencephalogram (“EEG”) data generated by an EEG device coupled to a plurality of electrodes disposed on a brain, the EEG data comprising a plurality of waveforms representative of electrical activity detected by the plurality of electrodes over a period of time; generate a graphical brain model representative of the brain; to convert the EEG data into a graphical EEG model representative of electrical activity; integrate the EEG model with the brain model, thereby enabling visualization of and interaction with the EEG model within the context of the brain model; and communicate the integrated EEG and brain model to a display.

Polymeric Microstructures and Systems and Methods for Making Same

Resumen de: US20260294795A1

Aspects of the present disclosure include polymeric structures (e.g., microneedles) having a lattice microstructure composed of one or more lattice cell units. Polymeric structures according to certain embodiments have repeating lattice cell units that are formed by high resolution continuous liquid interface production. Aspects also include systems for making polymeric structures having a lattice microstructure. Systems according to certain embodiments include a micro-digital light projection system having a light beam generator component and a light projection monitoring component and a liquid interface polymerization module having a build elevator and a build surface configured for generating the polymeric lattice microstructure from a polymerizable composition positioned therebetween. Methods for making polymeric structures having a lattice microstructure with the subject systems are also provided. Patches having an array of polymeric microneedles for applying to a skin surface of a subject are also described. In some embodiments, patches include microneedles that contain an active agent compound (e.g., an immunogenic active agent). Methods for applying the patches to the skin surface of a subject are also described.

Process control system for standardized blood pressure measurement and implementation method

Resumen de: US20260294256A1

Provided are a process control system and an implementation method for standardized blood pressure measurement. The system comprises a blood pressure measurement process control device and a built-in control module. The blood pressure measurement process control device comprises a computer host, a display, a control switch, and an electronic sphygmomanometer. The electronic sphygmomanometer is mounted in a body of the blood pressure measurement process control device by means of a fixing structure. The built-in control module controls the electronic sphygmomanometer to implement a set of blood pressure measurements in a patient, automatically completes the correlation and output of identity information and blood pressure measurement results of the patient, and generates an informationally complete blood pressure measurement report, thus reducing the measurement program error due to human-related causes and improving the credibility of the measurement results and the records while reducing the working intensity of the healthcare providers.

MEDICAL SERVICES KIOSK

Resumen de: US20260301938A1

0000 A medical services kiosk supporting private and secure telemedicine sessions between a patient and a remote network terminal utilized by a remote health care professional. The medical services kiosk comprising at least one privacy chamber having at least one door and at least one window. Each privacy chamber may include a user interactive display terminal that includes a display device, an input device, and a centralized processor, wherein the centralized processor is electronically communicable with the remote network terminal and a cloud based system. Each patient station may each include at least one documentation receiving device, at least one biometric device for obtaining biometric health measurements of the patient utilizing the at least one patient station, an arm mechanism, a seating mechanism, a camera, a retractable diagnostic camera device, a lighting mechanism that lights the privacy chamber, and a purification system.

CELLS, ISLETS, AND ORGANOIDS THAT EVADE IMMUNE DETECTION AND AUTOIMMUNITY, METHODS OF PRODUCTION AND USE THEREOF

Resumen de: US20260297530A1

0000 The invention features cells, islet-like cells, pancreatic islets and organoids (e.g., human islet-like organoids or HILOs), as well as cell cultures and methods that are useful for the rapid and reliable generation of cells and organoids, such as pancreatic islets and organoids, that are sustainable in vivo and that evade immune detection, rejection and autoimmunity. The invention also features methods of treating pancreatic diseases, such as type 2 diabetes, and pancreatic cancer, using the cells, islet-like cells, pancreatic islets and organoids (e.g., HILOs) that are designed to modulate the activity of immune cells that would otherwise react against them.

METHODS AND DEVICES FOR SECURE COMMUNICATION WITH AND OPERATION OF AN IMPLANT

Resumen de: US20260304110A1

The present disclosure relates to an apparatus for powering an implant for a human patient and a method for powering an implant for a human patient. Wherein said apparatus comprises an implantable energy source for providing energy to the implant, an energy provider connected to the implantable energy source and connected to an energy consuming part of the implant, the energy provider being configured to store energy to provide a burst of energy to the energy consuming part, wherein the energy provider is configured to be charged by the implantable energy source and to provide the energy consuming part with electrical power during startup of the energy consuming part.

Manufacturing method of transparent orthodontic device apparatus using 3D printer

Resumen de: US20260294596A1

0000 This invention provides a more efficient, cost-effective, and streamlined method for manufacturing transparent orthodontic devices by utilizing 3D printing technology. It simplifies the production process, reduces collaboration time, and ensures that the aligners are customized for the patient's specific orthodontic needs.

Processing Device, Processing Program, Processing Method, And Processing System

Resumen de: US20260294209A1

0000 A processing device is provided for processing an image obtained by imaging the inside of the oral cavity for use in diagnosis of the inside of the oral cavity. The processing device includes at least one processor. The at least one processor performs processing for acquiring one or more determination images of a subject through a camera for capturing an image of the subject including at least a part of a user's oral cavity, determining a possibility of contracting a predetermined disease based on a trained determination model stored in a memory to determine the possibility of contracting the predetermined disease and the one or more acquired determination images, and outputting information indicating the determined possibility of contracting the predetermined disease.

ELECTRONIC DEVICE AND DATA MANAGEMENT METHOD OF ELECTRONIC DEVICE

Resumen de: US20260301969A1

An electronic device according to an embodiment may include communication circuitry, a display, at least one sensor, a memory including a generative artificial intelligence model, and a processor. The memory may store instructions that, when executed by the processor, cause the electronic device to identify biometric data periodically measured using the at least one sensor, determine whether the biometric data is missing, identify information related to a period during which the biometric data is missing, identify a measurement history of previously measured biometric data, and generate, using the generative artificial intelligence model, missing biometric data based at least in part on the measurement history.

SYSTEM AND METHOD FOR ITERATIVE CLASSIFICATION PARAMETER GENERATION BASED ON REAL-TIME PHYSIOLOGICAL AND AUDIO INTERVIEW DATA

Resumen de: US20260301898A1

0000 A system for generation of diagnosis parameters based on patient-related data, including a processor and a memory on which are stored machine-readable instructions that when executed by the processor, cause the processor to: acquire sensory data from a plurality of biosensors; receive patient interview data comprising audio data generated during patient interview; derive a language metadata from the interview data; parse the interview data based on the language metadata to derive a plurality of key features; retrieve local historical patients'-related data related to previous patients'engagements associated with previous interview data based on the plurality of features; generate a feature vector based on the plurality of features, the sensory data and the local historical patients'-related data; and provide the feature vector to a ML module configured to generate a predictive model for producing a diagnosis for generation of the patient-related classification for the at least one medical entity node.

CLOSED-LOOP SLEEP MANAGEMENT METHOD, HEAD-WORN CLOSED-LOOP SLEEP MANAGEMENT SYSTEM, AND ELECTRONIC DEVICE

Resumen de: US20260295203A1

0000 A closed-loop sleep management method applied to a head-worn closed-loop sleep management device includes: performing sleep monitoring in real time based on an electroencephalogram (EEG) signal, an electrooculogram (EOG) signal, a heart rate (HR), and a blood oxygen saturation (SpO<2>); and controlling an intervention component to perform sleep intervention when a sleep monitoring result meets a preset condition. The sleep monitoring includes sleep staging and calculation of a duration of a current sleep stage. The sleep monitoring result includes the current sleep stage and the duration thereof. The method applies a deep learning algorithm to perform sleep staging and calculate the duration of the current sleep stage based on multi-modal signals, enabling real-time and accurate sleep state monitoring. Additionally, the method can achieve effective dynamic sleep intervention based on the sleep monitoring result, achieving closed-loop management from sleep monitoring to sleep intervention.

Health Safety and Status System, Service, and Platform, and Corresponding Methods

Resumen de: US20260301894A1

0000 A computer-implemented method includes accessing, by a processor of health safety credential platform, an access requirement associated with a venue or service; accessing, a certified health status record associated with an individual; comparing the certified health status record to the access requirement; determining an access determination according to one or more access-evaluation parameters comprising a disease identifier, a test type, a sample-collection time, a test-result time, a time to live value, a vaccination date, an effective date range, a geographic rule, and a validity period; generating a machine-readable access object representing the access determination; and encoding, the machine-readable access object to suppress health-status information utilized in generating the access determination while preserving information indicating the access determination.

SYSTEM AND METHOD FOR ACCURATE ELECTRODE SITE MEASUREMENT ON BODY SURFACES, INCLUDING SITES NOT VISIBLE TO LIDAR, USING CALIBRATED TACTILE PROBES AND MOTION COMPENSATION

Resumen de: WO2026199041A1

The present invention relates to a system and method for automated electrode or sensor site mapping and placement guidance on a subject's body surface, including regions obscured by hair, fur, or subject positioning. The system combines LiDAR- based three-dimensional scanning with calibrated tactile probes to generate an accurate model of the body surface. An external reference landmark system comprising three or more fixed fiducial markers provides a static coordinate reference frame to compensate for subject movement during scanning and placement guidance. A processing unit integrates LiDAR and probe data, calculates electrode or sensor site locations based on standard or custom placement systems, and provides guidance for site placement through visual, auditory, or haptic feedback. The system is applicable to clinical and research applications, including electroencephalography (EEG), neuromodulation, and animal studies, where accurate and reproducible electrode or sensor placement is essential. The system reduces operator dependency, compensates for motion, and improves placement accuracy and efficiency.

DENTAL ZIRCONIA 3D-PRINTED ARTICLE HAVING COLOR AND TRANSLUCENCY GRADIENTS AND MANUFACTURING METHOD THEREFOR

Resumen de: WO2026205957A1

The present invention relates to a dental zirconia 3D-printed article having color and translucency gradients and a manufacturing method therefor and, specifically, to a dental zirconia 3D-printed article and a manufacturing method therefor, the dental zirconia 3D-printed article comprising at least two types of yttria-stabilized zirconia (YSZ) doped with different contents of yttria (Y2O3), wherein the at least two types of yttria-stabilized zirconia are selectively doped with a colorant to have gradients in color and translucency.

DENTAL PRODUCT FORMED BY 3D PRINTING AND METHOD FOR MANUFACTURING DENTAL PRODUCT

Resumen de: WO2026200932A1

The present application relates to a dental product formed by 3D printing, comprising: a first body, comprising a portion made of a first material; and a second body, connected to the first body and comprising a portion made of a second material, wherein the first material and the second material have different colors or transparencies. The dental product provided in the present application meets at least one application requirement.

KINEMATIC RECOMMENDATION ACROSS DEVICES USING MACHINE LEARNING

Resumen de: WO2026206497A1

A system preparing kinematic recommendations for athletes using artificial intelligence is disclosed. The system is programmed to sense personal physical data regarding a subject athlete, and optionally review environmental data, and historical performance and physical data related to the subject athlete. The system produces performance recommendations for that subject athlete, determines a best medium for providing the performance recommendations to the subject athlete based on their personal physical data, and provides the performance recommendations to the subject athlete via that determined best medium. The best medium can include an augmented reality interface worn by the athlete. The performance recommendations can be prepared by machine learning or artificial intelligence models designed to analyze athletic performances, and to communicate conversationally with the athlete.

METHODS AND SYSTEMS FOR ASSISTING A DENTAL RESTORATION PROGRAMME

Resumen de: WO2026201517A1

Provided herein is a method (100) for preparing a prosthetic crown for a subject or assisting a dental restoration programme comprising one or more dental sessions for fitting a prosthetic crown into a subject, the method comprising: receiving a planning dataset, 3D- PLAN (120), wherein the 3D-PLAN comprises three-dimensional dental measurement data of the subject as presented prior to an intervention, wherein: the intervention includes implanting an implant in a defined pose for later addition of the prosthetic crown; and the 3D-PLAN: is used for a planning and execution of the intervention; and is used for a preparation of a preliminary design of the prosthetic crown; receiving a local 3D post- intervention measurement dataset, L3D-POI (140), wherein the L3D-POI has been obtained by a three-dimensional contactless measurement of the intervention site, wherein the intervention site comprises the implant, wherein the implant has been fitted to a jawbone of the subject to support the prosthetic crown, and the L3D-POI includes a three- dimensional measurement data of at least a coronal portion of the in situ implant; determining (200), from the 3D-PLAN (120) and L3D-POI (140), a 3D patient specific dental component, 3D PSDC, dataset (220), from which the 3D PSDC is able to be prepared; and outputting (230) the 3D PSDC dataset (220) for transmission (290) to a device (300) for additive manufacturing, thereby allowing an additive manufacture of a 3D printed PSDC, wherein the 3D p

THREE DIMENSIONAL PRINTABLE BIODEGRADABLE METAL INFUSED BONE REGENERATIVE MATERIAL UTILIZING ADDITIVE MANUFACTURING FOR BONE TISSUE ENGINEERING

Resumen de: WO2026207093A1

A bioactive composite filament for fused-deposition modeling comprises 10 vol% to about 60 vol% biodegradable metal powder (about 10 µm to about 100 µm particle size) and about 40 vol% to about 90 vol% biocompatible thermoplastic polymer. The filament exhibits controlled rheology (viscosity ≤ 5.5×10⁵ Pa·s at 120 °C), enhanced mechanical properties (up to 3-fold increase in tensile modulus), and printability with high fidelity (print score ≥ 0.85). Three-dimensional scaffolds manufactured from the filament demonstrate pH-neutral degradation, composition-tunable metal ion release, and sustained bioactivity with greater than 95% cell viability over 21 days. The manufacturing process involves cryogenic milling, inert-atmosphere blending, screw extrusion, and layer-by-layer deposition to produce porous scaffolds or non-porous implants for bone tissue engineering and orthopedic applications.

AUTOMATED TOOTH IMPLANT PLANNING

Nº publicación: WO2026202082A1 01/10/2026

Solicitante:

STRAUMANN INST AG [CH]
INSTITUT STRAUMANN AG

Resumen de: WO2026202082A1

A computer-implemented method for automated planning of a tooth implant in a dento-maxillofacial complex is described, wherein the method includes receiving or determining 3D virtual patient data representing a dento-maxillofacial complex comprising anatomical structures and at least one area of interest for placing the tooth implant, the 3D virtual patient data including 3D representations of anatomical structures within a vicinity of the at least one area of interest; determining a tooth implant model and/or one or more implant parameters defining a tooth implant model to be positioned at the at least one area of interest, using an implant planning engine, the implant planning engine being configured to receive the 3D representations of anatomical structures within a vicinity of the area of interest and to determine the tooth implant model and/or one or more implant parameters defining a tooth implant model based on clinical constraints, the clinical constraints including distance requirements of the tooth implant with regard to at least part of the 3D representations of the anatomical structures; and, rendering the implant model on a display or transforming the implant model into a data format for controlling a manufacturing apparatus, such as a 3D printer, to manufacture the tooth implant.