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Geometry Generation for Dental Restoration Appliances, and the Validation of That Geometry

Resumen de: US20260315197A1

Systems and techniques for training one or more machine learning models to generate digital representations of dental restoration tooth geometry are disclosed including generating one or more digital representations that define a restored state for a first digital representation, determining one or more differences between the one or more predicted representations for the restored state and the one or more reference representations of the restored state, and modifying the machine learning model based on the determined differences.

Prediction of bone based on point cloud

Resumen de: AU2026238109A1

A method for surgical planning includes obtaining, by a computing system, a first point cloud representing a first portion of a bone or a first cloud representing at least a portion of a bone, applying, by the computing system, a point cloud neural network to generate a second point cloud based on the first point cloud, the second point cloud comprising at least one of points representing at least a second portion of the bone or points representing an axis along the bone, and generating, by the computing system, surgical planning information based on the second point cloud. ep e p

AUTOMATIC DETERMINATION METHOD AND SYSTEM FOR ULTRASOUND ABLATION BALLOON APPOSITION

Resumen de: US20260315133A1

0000 Disclosed in the present invention are an automatic determination method and system for ultrasound ablation balloon apposition. The method comprises the following steps: setting related working parameters; after a balloon moves to a target ablation area, injecting normal saline; measuring a pressure in the balloon and an impedance outside the balloon, and feeding back same to a control system; and determining whether the balloon fits with the wall of a blood vessel well. According to the technical solution of the present invention, a pressure in a balloon and an impedance outside the balloon are measured at the same time and compared with set values and set change ranges, such that accurate and automatic determination of an ultrasound ablation balloon fitting with the wall of a blood vessel is achieved, and it is ensured that ablation operation is started after the ultrasound ablation balloon fits with the wall well, thereby greatly improving the ultrasonic transmission efficiency and the ablation operation effect.

IMPROVED METHOD AND SYSTEM FOR THE AUTOMATIC PROCESSING OF BONE IMAGES FOR ORTHOPAEDIC APPLICATIONS, IN PARTICULAR FOR DETERMINING THE PERSONALIZED IMPLANT BASED ON GROUPS OF BONES DEFECTS

Resumen de: AU2025257325A1

The present invention relates to a computer-implemented method for clustering defects of defective bones and manufacturing a patient-specific orthopaedic implant, including at least the following steps: - acquiring computed tomography CT images of a defective or damaged bone and feeding a database; - given a set of defective bones retrieved from said defective or damaged bone database, reconstructing a synthetic shape of the original shape of the defective bone; - computing a bone erosion depth map of said synthetic shape of the original shape of the defective bone, where said bone erosion depth map, for a given defective bone, comprises a set of erosion values over the region of interest of the reconstructed bone, defining an erosion vector; - transforming said erosion depth map into an erosion matrix which comprises the erosion vectors of the defective bones and the vertices over the surface of the region of interest of said synthetic shape of the original shape of the defective bone; - feeding said erosion matrix to an unsupervised machine learning algorithm that groups data into a tree of nested clusters, to identify clusters of relevant bone defects and to generate synthetic three-dimensional bone models representative of each defect cluster; - associating a defect label to each cluster; - training a defect classifier using said erosion matrix and said defect label to classify clusters of defects of the bones; - feeding a CAD environment with the outputs of said defect c

CURABLE COMPOSITION, THREE-DIMENSIONAL OBJECT PRODUCING METHOD, THREE-DIMENSIONAL OBJECT PRODUCING APPARATUS, AND ARTIFICIAL TOOTH OBJECT

Resumen de: US20260317554A1

A curable composition has a polymerizable monomer and a hard solid component having a volume average particle diameter of 10 nm or greater and 1,000 nm or less. The content of the hard solid component is 3% by volume or greater and 40% by volume or less. The difference (n1−n2) between the refractive index (n1) of a cured product of any other component than the hard solid component and the refractive index (n2) of the hard solid component is 0.04 or greater.

PRESCRIPTION BASED ORTHODONTIC TREATMENT PLATFORM

Resumen de: AU2025245072A1

Orthodontic treatment planning involves determining the desired treatment positions for a patient's teeth. The desired treatment positions may include both aesthetic and clinical considerations that describe the spatial relationship of teeth relative to each other. The inventors have recognized and appreciated that existing techniques, for orthodontic treatment planning, struggle to provide suitable orthodontic treatment plans without substantial involvement from orthodontic clinicians.

無細胞基材及び其れを作製する方法

Resumen de: WO2023133124A2

Acellular substrates that provide continuous 3D growth of a variety of cells and/or tissues and methods of making the same are provided. The acellular substrates have a three- dimensional (3D) macrostructure defined by a continuous matrix of extracellular matrix (ECM) material associated with a first cell type of interest and a network of microporous channels and/or chambers extending throughout the continuous matrix of ECM material associated with the first cell type of interest. Methods of forming a personalized graft using a patient's own cells is also provided.

SYSTEMS AND METHODS TO PROCESS GENERATIVE OR DYNAMIC VIDEO AND IMAGES TO TARGET HEALTHY NEURAL PATHWAYS

Resumen de: US20260320367A1

Systems and methods are disclosed for modulating neural pathways to improve functional ability in a subject. The systems and methods may contain steps, including: receiving a first dataset associated with activity of one or more neural pathways of the subject; receiving a second dataset comprising at least one of at least one task performed by the subject, at least one symptom, and at least one medical condition of the subject; determining one or more abnormal neural pathways based on the first dataset and the second dataset; determining from the second dataset, one or more healthy neural pathways associated with the one or more abnormal neural pathways based on one or more criteria; and determining, based on the healthy neural pathways and abnormal neural pathways, and using a non-invasive stimulatory device, a stimulus input focused or differentiated to the healthy neural pathways.

INFORMATION PROCESSING ASSESSMENT BOOTH

Resumen de: US20260321368A1

An information processing assessment booth may be provided with a base panel, having a trapezoidal surface defined in a first plane with a front edge parallel to a back edge, and first and second side edges disposed at a first angle between the front edge and the back edge; a first side panel attached to the first side edge of the base panel, extending perpendicularly to the first plane; a second side panel attached to the second side edge of the base panel, extending perpendicularly to the first plane; a roof panel, connected between the first side panel and the second side panel in a second plane that intersects the first plane; and a divider, connected between the first side panel, the second side panel, the roof panel, and the base panel, extending perpendicularly from the base panel and including a video display device and a video recording device.

DEEP LEARNING MODEL FOR DIAGNOSING PLAQUE EROSION USING CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY

Resumen de: US20260315020A1

0000 Systems and methods of deep-learning diagnosis of plaque erosion using coronary computed tomography angiography (CTA). One system may include one or more electronic processors configured to receive a plurality of CTA images for a patient having acute coronary syndromes (ACS) and apply a machine learning model to the plurality of CTA images to determine a plaque erosion prediction.

DETECTION OF EARLY-STAGE LUNG CANCER IN SPUTUM USING AUTOMATED FLOW CYTOMETRY AND MACHINE LEARNING

Resumen de: US20260321422A1

0000 A system and method for analyzing a sputum sample from a subject suspected of having lung cancer comprising obtaining a plurality of cells from the sputum sample from the subject, marking the plurality of cells with i) a plurality of cell lineage specific marker compositions, ii) a cell viability composition and iii) a tetra (4-carboxyphenyl) porphyrin (TCPP) composition; analyzing with the flow cytometer the plurality of cells marked with i-iii to obtain a subpopulation selected for cell size from the plurality of cells based upon an automatically selected bead size exclusion gate; from the cell size selected subpopulation, selecting a viable singlet population of cells using an automated non-debris gate and an automated singlets gate; from the viable singlet population of cells, obtaining flow cytometer values based upon the plurality of cell lineage specific marker compositions, the viability marker and the TCPP marker; applying a trained classifier to meta data from the subject and the flow cytometric values obtained; and generating, based upon the application of the trained classifier, a classification for the sputum sample wherein the classification is selected from a plurality of classification options comprising cancer and non-cancer.

バイオマーカー収集、双方向患者通信および長期的な患者フォローアップのための装置、システム、および方法

Resumen de: WO2023096914A1

Approaches for generating a set of biomarkers and generating a summary and one or more recommendations based, at least in part, upon the biomarkers are provided. Sensor data associated with a user may be received. The sensor data may be analyzed to generate a set of biomarkers. One or more biomarkers of the set may be combined to generate one or more additional biomarkers. A summary and one or more recommendations may be generated based, at least in part, upon the generated set of biomarkers and the additional biomarkers. The generated summary and the one or more recommendations may be provided for display on a client device.

BREATH TESTING DEVICES AND ANALYTICS

Resumen de: AU2025229905A1

The present invention provides an improved breath analyzer and breath test method to determine the presence of disease in humans, including but not limited to, H. pylori infection, Celiac Disease, Metabolic dysfunction-associated steatohepatitis (MAHD), Inflammatory Bowel Disease (JBD). 'm a subject's digestive tract. In certain embodiments, the present invention provides a universal breath testing platform and methods of testing for diseases of the gastrointestinal tract, the liver, the kidneys, and the lungs, along with testing for cancer, infections, and metabolic diseases.

VASCULAR PLANT BASED SCAFFOLD AND IN-VITRO METHOD FOR NEURAL STEM CELL CULTURE

Resumen de: US20260317704A1

A vascular plant based cellulose scaffold for in-vitro production or growth of neural stem cells is provided. The scaffold may be obtained by decellularizing a vascular plant or a part thereof and is capable of supporting the growth of neural stem cells. The scaffold may be coated with any traditional coating known in the art such as a biomolecule, a synthetic biomolecule (Poly-L-Ornithine), a ligand, a protein, an amino acid, an antibody, an extracellular matrix, fibrin, laminin, collagen, fibronectin, poly-l-lysine, a small molecule, a hydrogel, or a matrigel. An in-vitro method of growing or producing neural stem cells is also provided.

METHOD AND SYSTEM FOR USING SENSORS TO OPTIMIZE A USER TREATMENT PLAN IN A TELEMEDICINE ENVIRONMENT

Resumen de: US20260315872A1

0000 A method for optimizing at least one exercise for a first user. The method includes receiving first user data including attribute data associated with the first user and outcome data associated with the exercise. The method includes generating, based on the first user data, initial target data. The initial target data is associated with at least one of the first user, the exercise apparatus, and the exercise. The method includes receiving measurement data associated with at least one of the first user, the exercise apparatus, and the exercise. The measurement data is associated with one or more sensors. The method includes determining differential data based on one or more differences between the initial target data and the measurement data. The method includes generating, via an artificial intelligence engine and based on the differential data, a machine learning model trained to generate optimized target data.

METHOD FOR DESIGNING A TRANSPARENT ORTHODONTIC APPLIANCE AND ATTACHMENT FOR TOOTH ALIGNMENT

Resumen de: US20260315188A1

The method for designing a transparent orthodontic appliance and attachment for tooth alignment according to the present invention has been devised to solve the above technical problems. It is a method for designing an orthodontic appliance using a computer, comprising: a step (S01) of designing the shape of an attachment to be affixed to the surface of a tooth model; a step (S02) of designing the inner surface shape of the transparent orthodontic appliance corresponding to the attachment designed in step S01; and a step (S03) of outputting the transparent orthodontic appliance by means of a 3D printer. The attachment comprises: two pressure surfaces (101) formed to face each other; two inclined surfaces (201) formed to be inclined toward each other while contacting the two pressure surfaces (101); a top surface (301) contacting the edges of the two pressure surfaces (101) and the two inclined surfaces (201); and an attachment surface (401) affixed to the surface of a tooth. This configuration serves as the technical means for solving the problem.

CONNECTED BODY SURFACE CARE MODULE

Resumen de: US20260321429A1

0000 A wearable treatment and analysis module is provided. The module is positioned on or near a body surface region of interest. The module provides remote access to sensor data, treatment administration, and/or other health care regimens via a network connection with a user device and/or management system.

HEALTH MANAGEMENT SYSTEM

Resumen de: US20260321370A1

0000 According to an aspect, a health management system includes: a server; a user terminal device through which a user in a customer uploads biometric information to the server; an operator-side monitoring management terminal device through which the biometric information uploaded to the server is viewable and monitoring information on health management for the user is addable to the biometric information; and a customer-side monitoring management terminal device through which the biometric information uploaded to the server and the monitoring information added to the biometric information are viewable.

METHODS AND APPARATUS TO REDUCE ANXIETY WITH MIXED REALITY

Resumen de: US20260320927A1

Methods and apparatus to reduce anxiety using mixed reality are disclosed herein. An example method of reducing anxiety in a person during a blood collection process includes providing a mixed reality headset to a person prior to collecting blood from the person. The method includes initiating a mixed reality program on the mixed reality headset. The mixed reality program causes a display device to display a mixed reality environment with one or more virtual objects on glasses of the headset, determines a gaze direction of the eyes of the person, and causes a change in one or more of the virtual objects in the mixed reality environment based on the gaze direction. The method further includes collecting blood from the person while the person is exposed to the mixed reality program.

Systems and Methods for Surgical Field Item Detection

Resumen de: US20260315176A1

0000 Systems and methods are provided for a surgical instrument counting device for an operating room. An example system includes a collecting enclosure and a counting apparatus having a sensor configured for determining when an instrument is dropped into the collecting enclosure. The counting apparatus is configured to maintain a count of instruments introduced into a surgical field associated with the operating room and a count of instruments accounted for in the counting apparatus.

METHOD FOR INTELLIGENT INSTRUMENTS FOR MODULAR ENERGY SYSTEM

Resumen de: US20260315161A1

0000 Various methods are disclosed. One method includes reading an RFID card that is associated with a surgical instrument when the RFID card is located proximal to an RFID reader and initiating a wireless pairing process with the surgical instrument by the header module. Another method includes receiving an accessory at an accessory port of a modular energy system, communicating via a flexible serial communication interface coupled between a processor and the accessory port, the flexible serial communication interface configured to support multiple communication protocols, and detecting, by a presence detection circuit coupled between the accessory port and the processor, presence of the accessory connected to the accessory port. Other methods include a flexible serial bus power configuration method for a modular energy system and a remote power control interface method for a modular energy system.

動物データコンプライアンスシステム及び方法

Resumen de: WO2022150486A1

An animal data compliance system includes one or more sources of animal data from one or more targeted individuals wherein the animal data is transmitted electronically. A collecting computing device gathers the animal data. One or more rules related to at least a portion of the animal data are created or modified based upon one or more terms. The one or more rules are associated with at least a portion of the animal data. At least a portion of animal data and the one or more rules are provided to one or more receiving computing devices. The one or more rules informs the one or more receiving computing devices of one or more permissions or restrictions related to the animal data. The one or more receiving computing devices take at least one action based upon the one or more rules.

ISOLATED OLFACTORY MUCOSA MESENCHYMAL STEM CELLS AND BIOMATERIALS THEREOF FOR PROMOTING PERIPHERAL NERVE REGENERATION

Resumen de: EP4821500A1

The present invention relates to mesenchymal stem cells isolated from the olfactory mucosa (OM-MSCs) and respective secretome (OMS) integrated with biomaterials such as Neural Guide Conduits/Tubes (NGCs) to promote peripheral nerve regeneration.Therefore, it is herein disclosed a process of isolating OM-MSCs and the respective secretome, cell lines, secretome and culturing media for said OM-MSCs and OMS.Also disclosed is a process to obtain biomaterials comprising integrated OM-MSCs and OMS into NGCs, products and uses thereof.The integration of biomaterials with the cells per se or secretome optimizes the microenvironment, enhancing cellular survival, proliferation, and targeted regeneration of nerve tissues.This invention is in the field of mesenchymal stem cells, biomaterials comprising such cells and peripheral nerve regeneration in humans or animals.

HEALTHCARE MANAGEMENT METHOD

Resumen de: EP4822711A2

The present disclosure provides a healthcare management method comprising acquiring a first data that includes a glycoalbumin concentration and an albumin concentration in a body fluid from a subject; generating, on the basis of the first data, output information related to the GA value; and providing the generated output information to a user.

NFC AI SYSTEM AND METHOD FOR PROVIDING AI-BASED EMOTION-ADAPTIVE SCENT DIFFUSION SERVICES BASED ON WEARABLE BIOMETRIC DATA AND NFC SCENT PROFILES

Nº publicación: KR103032279B1 14/10/2026

Solicitante:

박동현