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CONFIGURABLE PHOTOPLETHYSMOGRAM SYSTEM

Resumen de: EP4725400A1

Methods, systems, and devices for optical signal measurement are described. A wearable electronic device may activate a first combination of optical sensors, the first combination of optical sensors including a set of transmitter sensors and a set of receiver sensors. In some cases, one or more optical sensor of the first combination of optical sensors may be positioned under a protrusion on an inner surface of the wearable electronic device. The device may measure, at the set of receiver sensors at a first time, one or more signals from the set of transmitter sensors, determine a signal quality metric associated with the one or more signals, and select a second combination of optical sensors for use at a second time based on the signal quality metric.

原発性骨腫瘍の診断支援システム、診断支援方法及び診断支援プログラム

Resumen de: JP2026065297A

0001 【課題】より精度の高い原発性骨腫瘍の診断支援の実現を提供する。 【解決手段】Ｘ線画像による原発性骨腫瘍の診断支援システムであって、前記Ｘ線画像を入力した際に畳み込みニューラルネットワークによって骨腫瘍であるかの判定結果を出力する処理手段を備え、前記畳み込みニューラルネットワークが、骨外腫瘍、骨皮質部及び骨内腫瘍の３クラスとして腫瘍存在範囲をアノテーションされた確定診断Ｘ線画像を教師データとして学習処理されたものであることを特徴とする、原発性骨腫瘍の診断支援システム。 【選択図】図１

COMPUTER IMPLEMENTED METHODS AND SYSTEMS FOR GENERATING MODELS OF BONES, AND FOR ADDITIVE MANUFACTURING OF BONES

Resumen de: EP4725455A1

The present disclosure relates to computer-implemented methods (100) for generating a virtual model of a first section of bone tissue including cortical bone tissue. The method comprises (104) obtaining microstructural cortical parameters including an indication of a number of osteons (210) and of a cross-sectional area of the osteons, a number of lamellae (212) forming the osteons, an indication of locations of osteons in the section of bone tissue and of dominance of the osteons. The method further comprises generating a virtual model using a generative design algorithm comprising (1061) defining a geometric space, (1062) generating a cortical cloud of points, (1064) segmenting the geometric space into substantially circular regions, defining an outer surface of the osteons. The method further comprises (1065) forming consecutive substantially concentric surfaces corresponding to the lamellae until the obtained virtual model satisfies boundary conditions formed by the microstructural cortical parameters.

POWERED ORAL CARE IMPLEMENT INCLUDING A TRACKING MODULE AND TRACKING MODULE AND TRACKING MODULE THEREOF

Resumen de: EP4725359A2

0001 An oral care system that includes an oral care implement and a tracking attachment. The oral care implement may include a handle and a head. The tracking attachment is detachably coupled to the oral care implement. The tracking attachment may include a first component comprising a first housing having an inner surface that defines a first cavity and a second component comprising a second housing having an inner surface that defines a second cavity. When the tracking attachment is coupled to the oral care implement, a first portion of the handle is positioned within the first cavity and a second portion of the handle is positioned within the second cavity.

PRE-CONNECTED ANALYTE SENSORS

Resumen de: EP4725401A2

A system (101) for measuring an analyte concentration in a host comprises a transcutaneous analyte sensor (138); a bottom housing (522); a top housing (520); and sensor electronics (112) configured to connect to the transcutaneous analyte sensor (138). The sensor electronics (112) are configured to be disposed between the bottom housing (522) and the top housing (520). The bottom housing (522) includes a recess (726) with a floor (704), and the floor (704) includes a plurality of locating pins (784, 786), the plurality of locating pins (784, 786) extending upward from the floor (704). The plurality of locating pins (784, 786) are configured to extend into a plurality of holes (794, 796) in a substrate (404). A conductive member (762, 764) is configured to establish electrical connection between the sensor (138) and the sensor electronics (112).

3D METHOD DEVICE SYSTEM AND COMPUTER PROGRAM FOR MANUFACTURING THROUGH 3D MODELING OF CUSTOMIZED ORAL DEVICE FOR SLEEP DISORDER IMPROVEMENT

Resumen de: KR20260050994A

0001a 본 발명의 다양한 실시예에 따른 수면 장애 개선을 위한 맞춤형 구강 장치의 3D 모델링 방법이 개시된다. 상기 방법은, 상악 모델 및 하악 모델을 포함하는 치아 모델을 생성하는 단계, 상기 치아 모델에 기초하여 윤곽 정보를 생성하는 단계, 상기 윤곽 정보에 기초하여 복수 개의 파츠 모델을 생성하는 단계 및 상기 복수 개의 파츠 모델을 통합하여 구강 장치 모델을 생성하는 단계를 포함할 수 있다.

整形外科用膝プロテーゼの金属強化ポリマー大腿骨コンポーネント及びそれを作製する関連方法

Resumen de: US12569347B2

An orthopaedic knee prosthesis includes a femoral component having a metal base with a polymer articular layer molded thereto. A method for making a metal-reinforced femoral component of an orthopaedic knee prosthesis is also disclosed.

モジュール式エネルギーシステム

Resumen de: WO2022208280A1

A modular energy system is disclosed including a header module including an enclosure and a display including a coupler. The enclosure defines a recess. The recess includes a first guidewall and a second guidewall. The coupler is removably positionable in the recess. The coupler includes a first sidewall and a second sidewall. The first guidewall is configured to guide the first sidewall as the coupler moves through the recess. The second guidewall is configured to guide the second sidewall as the coupler moves through the recess.

神経変性疾患に関連付けられる症状の重症度の自動分類

Resumen de: WO2024196387A1

A method of classifying severity of symptoms associated with neurological disorders, including receiving sensor data from a device that includes one or more sensors; extracting data features from the received sensor data; generating a context of a patient's state based on the extracted data features; determining a symptom associated with a neurological disorder, based on the extracted data features and the context of the patient's state; predicting using a symptom severity classifier, a severity of the determined symptom, based on the extracted data features and the context of the patient's state; and outputting the determined symptom and the predicted severity of the determined symptom.

一种个性化阶梯式3D打印鼻矫形鼻腔支架及使用方法

Resumen de: CN121845825A

0001 本发明涉及鼻整形技术领域，具体为一种个性化阶梯式3D打印鼻矫形鼻腔支架及使用方法，包括用于支撑鼻翼的鼻腔支架，鼻腔支架的外表面固定连接有膨胀块，两个鼻腔支架通过连接块6连接，形成一个完整的支架。该个性化阶梯式3D打印鼻矫形鼻腔支架及使用方法，通过将患者原始鼻腔形态与正常鼻腔形态建立动态拟合，在过程中打印若干支架，鼻腔支架的数量根据患者的鼻畸形情况设置，形成双侧鼻畸形形阶梯式鼻矫形支架，患者在佩戴治疗时，通过将鼻腔支架从原始鼻腔形状向正常鼻腔形状渐变，可以有效减少患者佩戴支架时的不适感。

基于非侵入式脑机接口的睡眠质量监测与分析方法、装置、设备及存储介质

Resumen de: CN121845615A

0001 本申请公开了一种基于非侵入式脑机接口的睡眠质量监测与分析方法、装置、设备及存储介质，涉及脑电信号处理技术领域，所述方法包括：对原始脑电信号进行预处理，并从预处理后的信号中提取脑电特征频段信息，基于各频段的均值、标准差及功率占比构建多维特征向量，利用滑动窗口与随机森林模型划分深睡期、浅睡期和快速眼动期并计算其占比，再结合睡眠阶段连续序列计算睡眠稳定性参数，融合各睡眠阶段占比、稳定性参数和信号质量参数通过加权方式生成睡眠质量评分，最终根据评分、阶段占比和频段信息生成可视化报告与睡眠改善建议，完成睡眠质量的监测与分析。本申请能够兼顾睡眠质量监测与分析的高精度与易用性。

一种脊柱侧凸的智能矫正评估系统及方法

Resumen de: CN121845814A

本发明属于矫正智能控制技术领域，公开了一种脊柱侧凸的智能矫正评估系统及方法，基于智能多模块传感器，搭建脊柱侧凸智能矫正系统；基于人体三维表面形貌测量技术，建立脊柱侧凸智能评估系统；基于智能多模块传感器与可穿戴超声图像设备，评估脊柱矫正时脊柱相关肌肉的内部形态和活动特征；结合脊柱侧凸矫正策略与脊柱矫正效果和脊柱相关肌肉活动特征，综合分析脊柱侧凸矫正机制，确定最佳生物力学矫正策略。本发明对脊柱施加外力实现脊柱畸形的控制，通过对脊柱侧凸矫正机制分析，揭示不同矫正策略产生的矫正效果，有助于提高脊柱侧凸患者保守治疗疗效，对提高患者生活质量，降低家庭经济负担，减轻医疗体系压力具有重要意义。

METHOD FOR DESIGNING PATIENT-SPECIFIC MANDIBULAR GUIDANCE AND DEVICE OFFERING IMPLANT AND PATIENT-SPECIFIC MANDIBULAR GUIDANCE THEREOF

Resumen de: KR20260050323A

환자 맞춤형 하악 가이던스를 설계하는 장치에 있어서, 환자의 하악골 이미지를 입력받는 입력부; 상기 입력된 하악골 이미지를 기반으로 환자의 해부학적 구조를 분석하고, 상기 분석된 환자의 해부학적 구조를 기초로 하악골 절제 부위 및 나사 위치를 포함한 하악 가이던스를 3차원으로 모델링하는 프로세서; 및 상기 모델링된 하악 가이던스를 표시하는 출력부;를 포함하는, 환자 맞춤형 하악 가이던스를 설계하는 장치를 제공한다.

根据非对比计算机断层摄影的射血分数

Resumen de: EP4725423A1

0001 For segmentation (310) and/or ejection fraction determination (320), photon-counting detection (100) for CECT in ES is used to create (110) virtual NCCT for machine training (130). The lack of NCCT data at ES for training (130) segmentation is overcome by use of the virtual NCCT. Since the segmentation (310) is trained (130) on non-contrast imaging at ES, accurate ES segmentation (310) from NCCT may be provided. The EF may be calculated (320) using NCCT.

バイオポリマーの官能化方法及びその架橋方法

Resumen de: WO2024196271A2

The invention relates to a method of functionalizing a biopolymer in which a biopolymer having -OH or -NH2 groups is reacted with at least one compound containing at least one C=C or C≡C bond and a chromophore group absorbing UV-Vis radiation directly adjacent to this bond. The invention also relates to a method for obtaining a solid biopolymer material, in which the functionalized biopolymer obtained by the method specified above is subjected to reversible cross-linking upon exposure to light in the UV-VIS range. The invention also relates to the use of a functionalized biopolymer as a support material for 3D bioprinting, as well as the use of a functionalized biopolymer for the production of structures selected from spheroids, organoids, artificial organs, coatings, and tissue models.

Method and system for confirmation of microneedle-based analyte-selective sensor insertion into viable tissue via electrical interrogation

Resumen de: US12599337B1

A system and method to confirm the insertion of an analyte-selective sensor comprising an array of microneedles possessing vertical extent between 200 and 2000 μm into viable tissue is disclosed herein. Mechanical insertion of an analyte-selective sensor is firstly attempted by means of an application of external force. Either during or following this routine, an electrical stimulus is applied between at least two distinct electrodes located within the said analyte-selective sensor; a resultant response is measured. This response is compared with a reference value to determine if insertion was successful. If insertion was successful, no further effort is required and the sensor can operate as intended. However, if insertion was not successful, the user can be instructed to continue to apply additional force to said sensor to achieve successful insertion or otherwise re-apply the said sensor altogether.

System and method for providing dental services to a patient

Resumen de: US12603181B1

0000 A system and method providing a dental patient user interface to allow a patient to accurately scan existing patient dentures to provide a digital image for use by a provider to assess the needs and interests of the patient prior to a visit to then provide treatment facilitating/smile preview devices for use at the initial visit.

一种具有压力感知及自适应调节功能的智能防压疮床垫

Resumen de: CN121845873A

本发明公开了一种具有压力感知及自适应调节功能的智能防压疮床垫，包括床垫本体、可控气囊阵列、弹性垫、柔性压力传感器阵列、床垫外套和智能控制系统。本发明的具有压力感知及自适应调节功能的智能防压疮床垫，采用主动预测与个性化智能调节，基于患者的个体差异和行为模式，建立个性化压力模型和动态压力平衡算法，实现压力的精准调节和提前预测，有效预防压疮的发生，降低压疮发生率。

METHOD APPARATUS AND COMPUTER PROGRAM FOR CALCULATING BIOLOGICAL EFFECTIVE DOSE

Resumen de: KR20260050188A

본 발명에 따른 방사선량 산출 방법은, 대상체에 대한 입력데이터 -상기 입력데이터는 상기 대상체에 대한 기능 영상 및 해부 영상을 포함함- 를 수신하는 입력 단계, 상기 입력데이터에 기초하여 물리적 방사선량을 산출하는 제1 산출 단계 및 상기 물리적 방사선량에 기초하여 생물학적 유효 방사선량을 산출하는 제2 산출 단계를 포함하고, 상기 제1 산출 단계 및 제2 산출 단계는, 몬테카를로 기법에 기초하여 생성된 학습데이터를 이용하여 학습된 신경망 모델에 의한 제1 방식에 기초하여 수행되거나, 소정 수식에 의한 제2 방식에 기초하여 수행된다. 본 발명에 따르면, 인체 등 대상체의 조직에 대한 방사선량을 빠르고 정확하게 산출할 수 있게 되고, 핵종 또는 방사선의 종류 등에 따른 생물학적 유효 방사선량을 높은 정확도로 산출할 수 있게 된다.

WEARABLE ELECTRONIC APPARATUS FOR DETERMINING USER'S STATUS INFORMATION BASED ON USER'S BIOELECTRICAL SIGNAL AND CONTROL METHOD THEREOF

Resumen de: KR20260049425A

0001a 웨어러블 전자 장치가 개시된다. 본 웨어러블 전자 장치는 사용자의 귀에 착용되며, 제1 하우징 파트 및 제1 하우징 파트에 연결되는 제2 하우징 파트를 포함하는 하우징, 인스트럭션들을 저장하는 메모리, 제1 하우징 파트에 배치되며, 귀의 제1 면에 접촉되는 제1 전극, 제2 하우징 파트에 배치되며, 귀의 제2 면에 접촉되는 제2 전극, 제2 하우징 파트에 배치되며, 사용자의 매스토이드(mastoid) 영역에 접촉되는 제3 전극 및 프로세싱 회로(processing circuitry)를 포함하는 하나 이상의 프로세서를 포함하고, 인스트럭션들은, 하나 이상의 프로세서에 의해 개별적으로 또는 집합적으로(individually or collectively) 실행될 시, 웨어러블 전자 장치가 사용자에게 착용된 동안, 사용자의 귀의 제1 면에 접촉된 제1 하우징 파트의 제1 전극, 사용자의 귀의 제2 면에 접촉된 제2 하우징 파트의 제2 전극 및 사용자의 매스토이드 영역에 접촉된 제2 하우징 파트의 제3 전극을 통해 사용자의 생체 전기 신호를 획득할 수 있다.

一种用于修复下颌骨大范围缺损的3D打印PEEK网络支架的制备方法

Resumen de: CN121845802A

本发明公开了一种用于修复下颌骨大范围缺损的3D打印PEEK网络支架的制备方法，所属领域为生物医学工程与口腔修复领域，包括：通过引入力学计算公式，依据局部应力分布反推支架在特定区域所需的弹性模量，进一步优化支架的微观结构，确保支架在整个修复过程中能够动态适应骨组织的生长需求，从而有效促进内源性骨和血管的再生。

一种基于预制牙齿和CADCAM技术的牙科修复体制作方法

Resumen de: CN121845779A

本发明提供了一种基于预制牙齿和CADCAM技术的牙科修复体制作方法本发明公开了一种基于预制牙齿和CAD/CAM设备的牙科修复体制作方法，属于牙科修复体技术领域。该方法包括：预定义具备定位基准功能的加工工装；基于患者口内扫描模型选定预制牙齿，设计数字化修复义齿数据；生成义齿型盒三维数据（腔体由义齿表面法向反转所得）；合并加工工装、型盒和修复义齿，生成组织面切削路径；3D打印或切削制作实物型盒；插入预制牙齿并注入牙龈材料，凝固形成修复体毛坯；通过CAD/CAM设备切削加工组织面并抛光完成制备。本发明整合了预制牙齿的质量稳定、成本低廉优势与CAD/CAM技术的高效精准优势，避免了粘接精度误差，个性化适配性强，不依赖技师手工技艺，可批量化生产，制备的修复体形状精准、颜色自然，能满足患者功能与美学需求。

一种基于HAMA脂肪细胞微球与乳腺类器官的3D打印乳腺的方法

Resumen de: CN121845797A

本发明提供一种基于HAMA脂肪细胞微球与乳腺类器官的3D打印乳腺的方法，涉及生物医学技术领域，旨在解决现有技术中结构功能模拟不完整、细胞存活率低及分布不均等问题。核心技术方案包括：以HAMA脂肪细胞微球作为脂肪层功能单元，乳腺类器官作为腺体层单元，通过双喷嘴3D打印机实现双层结构的精准定位；通过调控HAMA交联度和微球孔隙率，提升脂肪细胞存活率；采用专用生物墨水和优化打印参数，使功能单元团聚率≤5%，并在界面设置交联过渡层促进结构连接；通过添加明胶和双重交联工艺，使模型压缩模量达10‑15kPa，降解周期3‑6个月，兼具良好力学性能和生物相容性。本申请有效地模拟乳腺生理微环境，在组织工程重建、药物筛选和疾病研究等领域具有重要应用价值。

用于关节假体的锆基合金原位氧化涂层的制备方法、医用关节假体及应用

Resumen de: CN121852847A

本发明公开了用于关节假体的锆基合金原位氧化涂层的制备方法、医用关节假体及应用，该方法适用于电子束熔化（EBM）、选择性激光熔化（SLM）制备或锻造加工的锆基合金（含 Zr‑2.5Nb、Zr‑Nb‑Ti、Zr‑Mo‑Nb 等体系），通过反复创建氧浓度梯度促使氧原子向材料内部扩散，精确形成高氧扩散过渡层与ZrO₂基原位氧化陶瓷涂层，同时建立氧化温度（T）‑陶瓷涂层厚度（d）‑耐磨性（WR）的耦合数学模型，实现涂层性能与产品尺寸的双重精准调控。本发明制备的涂层与基体通过高氧扩散过渡层紧密结合，过渡层深度超越传统工艺 40% 以上，氧化后假体尺寸变化量≤±0.01mm；涂层表面硬度≥1053Hv，磨损率≤0.8×10⁻⁶mm³/(N・m)，显著提升锆基合金的耐磨性能与尺寸稳定性，解决了关节假体长期服役中磨损碎屑导致的无菌性松动及尺寸精度失控问题，适用于髋关节、膝关节等医用关节假体的规模化生产。

基于AI与3D打印的多孔钽牙种植体的制造方法

Nº publicación: CN121845774A 14/04/2026

Solicitante:

大连大学附属中山医院

Resumen de: CN121845774A

本发明提供一种基于AI与3D打印的多孔钽牙种植体的制造方法，涉及口腔医学与3D打印技术领域，包括：S1、建立历史CBCT数据集；使用历史CBCT数据集在AI建模平台中基于深度学习算法进行训练构建口腔重建模型；S2、根据患者口腔的CBCT生成相应的口腔重建模型；种植体三维模型包括牙冠、牙基座和种植基体；种植基体具有梯度多孔结构，由上至下分为孔隙率和孔径逐渐降低的表层区、过渡区和核心区；S3、调节种植体三维模型的形状和尺寸，对种植体三维模型进行优化；S4、3D打印得到种植体；S5、在种植基体的外表面以及内部孔隙的内壁表面制备羟基磷灰石涂层。本发明解决了现有技术中存在的种植体弹性模量不匹配、骨整合效率低及修复体适配性差的问题。