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一种微透镜、其制备方法及应用

Resumen de: WO2025120669A1

The present disclosure provides a three-dimensional hydrogel prepared using a bioink composition comprising methacrylated hyaluronic acid, methacrylated gelatin, a photoinitiator and a photoabsorber; and a method for preparing the three- dimensional hydrogel or lenticule. The present disclosure further provides a method of treating corneal tissue repair in a subject in need thereof using the three- dimensional hydrogel or lenticule.

使用从全切片图像（WSI）得出的信息更新放射治疗计划

Resumen de: WO2025165561A1

Systems (600) and methods (S100) for adapting treatment plans to the characteristics of individual anatomical pathologies (e.g., tumors), and systems, methods, and devices for implementing an adaptive therapy workflow (220) that automatically updates (S103) treatment plans based on whole slide images (WSIs) of the target anatomical pathologies.

人工弁の外径を推定するシステムおよび方法

Resumen de: EP4693192A2

0001 The present invention relates to systems and methods for estimating prosthetic valve expansion diameter, and in particular, for system and methods for analyzing images acquired during prosthetic valve expansion, to identify structural components of the valve, determine dimensions thereof, and estimate at least one outer diameter of the prosthetic valve, and potentially a plurality of outer diameter along different axial positions of the prosthetic valve.

用于扩展医疗成像系统和设备的功能的信号处理板

Resumen de: WO2025165661A1

A computing system includes a plurality of signal processing boards configured to perform operations. Operations performed by a first signal processing board of the signal processing boards include: receiving a data signal from an image sensor of a medical device removably connected to the computing system; determining whether to route the data signal to a second or third signal processing board of the signal processing boards based on information associated with the image sensor, including characteristic(s) associated with the data signal, indicative of native or non-native support by the computing system; and, based on a determination of non-native support, providing the data signal to the third signal processing board. The third signal processing board is an expansion board removably connected to the computing system, and configured to perform operations, including: manipulating the data signal; and providing the manipulated data signal to the second signal processing board for processing.

一种3D打印抗炎生物可降解气道支架的制备方法

Resumen de: CN122624763A

本发明公开了一种3D打印抗炎生物可降解气道支架的制备方法，采用可降解生物材料3D打印技术制备定制化的气道支架，再对其进行表面功能化，表面接枝抗炎药物布洛芬，进一步制备具有抗炎功能的可生物降解气道支架。此支架提供长期的力学支撑的同时降低植入部位的炎症反应，从而为快速制备用于临床应用的个性化可降解气道支架提供新的解决方案。制备方法包括：利用3D打印技术制备定制化气道支架；利用表面改性手段，获得支架表面交联的胺化支架；再进一步利用布洛芬与表面氨基的酰胺化反应获得具有抗炎功能的气道支架。本发明工艺可重复性好，个性化定制性能优良，可作为治疗中央气道阻塞的有效手段。

用于医疗装置的控制架构

Resumen de: WO2025160362A1

Methods and apparatus for controlling a medical device are provided. A controller may include a first computing device configured to control the medical device, a second computing device configured to connect to at least one network device, and a processor configured to selectively enable or disable a switchable data communication network coupled between the first computing device and the second computing device.

運動障害のための遠隔リハビリテーション治療のシステムおよび方法

Resumen de: WO2025029698A1

A system for remote rehabilitation of a movement disorder of a patient is presented. A system includes a wearable device. A wearable device includes a sensor configured to generate movement data of a patient. Movement data is indicative of one or more movement disorder symptoms of a patient. A wearable device includes a processor in communication with a sensor. A wearable device includes a stimulator in communication with a processor. A processor is configured to cause a stimulator to stimulate a body part of a patient based on movement data. A wearable device includes a wireless communication unit in communication with a processor. A system includes a virtual platform running on a server in communication with a wearable device via a wireless communication unit. A virtual platform is programmed to receive movement data from a wearable device.

IV COMPOUNDING SYSTEMS AND METHODS

Resumen de: US2019164635A1

Systems and methods of compounding of medication include a user interface that enables efficient design of compounding workflows and protocols. A user can select a workflow type from a number of workflow types differentiated at least in part by the vehicle in which a compounded pharmaceutical is to be delivered, and the user may also specify a compounding device. Options are presented and the steps of a workflow in accordance with the workflow type and options is displayed and updated in real time as options are selected. A protocol can be constructed by inserting information into the workflow based on a specification of a particular pharmaceutical to be compounded.

マルチパラメータ代謝脆弱性指数評価

Resumen de: US2019072572A1

Disclosed are methods and systems to determine a subject's metabolic vulnerability index (MVX) score using at least one defined mathematical model of risk. The methods comprise evaluating various biomarkers to distinguish various health risks. In one embodiment, the method comprises evaluating biomarkers to determine a relative risk of premature all-cause mortality. The model may include NMR-derived measurements of GlycA, S-HDLP, branched chain amino acids (BCAAs), ketone bodies, total serum protein, and citrate in at least one biosample of the subject.

一种葡萄糖/氧化应激双响应双层水凝胶敷料、制备方法及其应用

Resumen de: CN122624726A

本发明涉及生物医用材料技术领域，特别是涉及一种葡萄糖/氧化应激双响应双层水凝胶敷料、制备方法及其应用，所述的双层水凝胶敷料在糖尿病伤口高糖、高活性氧的病理微环境中，交联网络响应性解体，释放负载的功能模块；在正常组织或愈合后期微环境趋于正常时，材料保持稳定；具有早期感染控制、中期能量补给与免疫调节、晚期基质重塑与疤痕抑制的全周期治疗需求，在促进糖尿病伤口高质量、无疤痕愈合方面的卓越效果和深远的临床转化潜力。

一种3D打印气管支架及其制备方法

Resumen de: CN122624218A

本发明公开了一种3D打印气管支架及其制备方法，该支架包括多个经向单元和多个纬向单元：经向单元由第一经向连接段、第二经向连接段及连接两者的经向内凸弹性段构成；纬向单元由第一纬向连接段、第二纬向连接段及连接两者的纬向内凸弹性段构成；多个经向单元沿不同经度方向依次串联形成多条经向链，多条经向链周向间隔布置；多个纬向单元分别连接于相邻经向链之间，与经向链共同形成柱状网格支架。本发明通过经向内凸弹性段与纬向内凸弹性段的几何‑力学耦合特性，实现了支架支撑与顺应功能的解耦，从根本上消除了支架移位的力学根源。

基于热-力耦合优化的PEKK颅骨补片增材制造支撑方法

Resumen de: CN122626477A

本发明公开了一种基于热‑力耦合优化的PEKK颅骨补片增材制造支撑方法，属于高性能聚合物增材制造技术领域。该方法通过对PEKK复杂曲面薄壳颅骨补片打印过程中的热场、应力场及曲率分布进行分析，构建曲率驱动的梯度支撑体系，并提出主承载脊柱‑热缓冲枝杈双级支撑网络，实现打印稳定性、热变形控制及材料利用率之间的协同优化。本发明能够显著降低PEKK颅骨补片FFF打印过程中的热翘曲与支撑耗材量，具有良好的工程应用价值。

一种具有骨诱导活性的聚肽仿生纳米纤维支架及其制备方法与应用

Resumen de: CN122624735A

本发明属于医用生物材料技术领域，尤其是涉及一种具有骨诱导活性的聚肽仿生纳米纤维支架及其制备方法与应用。本发明采用合成聚肽，通过表面引发聚合在铋取代羟基磷灰石上接枝PBLG，解决颗粒团聚及界面问题；引入含双键共聚物PBLG‑co‑(LG‑g‑APEG)，经3D打印交联形成共价网络增强力学性能；结合相分离获得仿ECM纳米纤维结构。本发明所得支架兼具宏观大孔和微观仿生纤维网络，有机无机杂化组分提供矿化界面，铋离子释放促成骨，实现骨缺损修复。

医用加药配药辅助装置

Resumen de: CN224671822U

0001 本实用新型公开了一种医用加药配药辅助装置，包括配置台、显示屏、扫描组件、提醒组件和摆药盒，所述显示屏设置在配置台的一侧并扫描组件相连接，扫描组件位于显示屏的一端并连接在配置台的上方，提醒组件设置在配置台的上方并位于扫描组件的一侧，且提醒组件与扫描组件相连接，摆药盒位于扫描组件的下方并设置在配置台的内部，本实用新型在医务人员拿取未配置完成的药液时，提醒组件可以通过蜂鸣器和红灯对医务人员发出警报提醒，从而避免医务人员取错药物。

一种基于双源验证与虚实同步的耳穴教学训练系统及方法

Resumen de: CN122637656A

0001 本发明公开了一种基于双源验证与虚实同步的耳穴教学训练系统及方法，其系统包括耳廓模型、耳穴压力笔以及上位机，耳廓模型上设置有霍尔感应阵列单元，耳穴压力笔、霍尔感应阵列单元与上位机通信连接，上位机中包括数据处理单元、三维虚拟渲染单元、以及档案管理单元；其方法包括通过耳穴压力笔将穴位压力信息和穴位位置信息上传给上位机，通过上位机的对齐、交叉验证后得到学员综合评分，提高数据评估的准确性；三维虚拟渲染单元能够根据穴位压力信息和穴位位置信息在虚拟耳穴模型上实时生成响应动画信息，且霍尔感应阵列单元根据学员的按压操作产生响应视觉信息，对学员的按压操作可以虚实同步地进行反馈，增强学员教学训练过程中的沉浸感。

多源传感器兼容的宠物口腔影像采集与协同处理系统及设备

Resumen de: CN122624110A

本发明涉及宠物医疗影像处理的技术领域，公开了多源传感器兼容的宠物口腔影像采集与协同处理系统及设备；所述系统包括：主控制模块，用于初始化、监听各模块发出的状态信号、管理采集状态以及协调各模块之间交互；多协议设备管理模块，其输入端用于电性连接至少一种口腔影像传感器，其输出端与所述主控制模块电性连接，用于通过操作系统底层接口动态扫描并识别所述传感器，为每个传感器建立统一的设备描述子，并为每个传感器维护独立的工作目录以隔离配置文件。本发明通过多协议设备管理模块统一接入不同厂商和接口的传感器，结合独立工作目录与热插拔检测，实现了即插即用和配置隔离，避免了换设备就得换软件的繁琐。

一种麻醉围手术期患者情绪实时监测与主动安抚系统

Resumen de: CN122624070A

本发明涉及医疗监测与护理技术领域，具体的说是一种麻醉围手术期患者情绪实时监测与主动安抚系统，包括多维度生物信号感知模块、时空关联情绪预测引擎、神经反馈式主动安抚模块、手术事件联动单元和医护智能决策终端。多维度生物信号感知模块融合肌电潜意识情绪捕捉、唾液皮质醇微流控快速检测与非接触式生理监测技术，实现主观情绪与客观生物标志物的同步采集；时空关联情绪预测引擎基于手术事件时序特征和患者历史数据，提前预测情绪波动风险；神经反馈式主动安抚模块通过经皮电刺激与多感官协同输出，形成情绪调节闭环；手术事件联动单元与手术室设备实时交互，在关键操作节点自动触发预安抚机制。

Three-dimensional reconstruction of interiors of closed containers

Resumen de: US12715123B1

A system for three-dimensional (3D) reconstruction of interiors of a closed container (e.g., a refrigerator) is provided. A track is mounted inside the refrigerator. A robot is configured to navigate along the track. The robot may include control modules and puller and pusher modules that are magnetically coupled to the control modules. The puller module may pull the control modules along the track, whereas the pusher module may push the control modules along the track. Each control module may include an image sensor that captures images of the physical space inside the refrigerator. The track is mounted such that by navigating along the track, the robot (e.g., the image sensors) can capture an entire scene of a physical space inside the refrigerator from different angles and locations within the refrigerator. Based on the captured images, a 3D representation of the physical space is generated.

マルチオミクス評価

Resumen de: WO2022212583A1

Described herein are methods such as multi-omic methods for assessing a disease such as cancer. The multi-omic methods may integrate proteomic, transcriptomic, genomic, lipidomic, or metabolomic data. The method screening diseases or disease states. Also described herein are methods for screening for diseases or disease states from biological samples. The methods may include assessing whether a nodule, mass, or cyst is cancerous.

Emergency cardiac and electrocardiogram electrode placement system with artificial intelligence

Resumen de: US12714353B1

0000 An emergency cardiac and electrocardiogram (ECG) electrode placement device with artificial intelligence is disclosed herein. The emergency cardiac and electrocardiogram (ECG) electrode placement device incorporates electrical conducting materials and elastic material into a pad that is applied to a chest wall of a patient, which places multiple electrodes in the appropriate anatomic locations on the patient to quickly obtain an ECG in a pre-hospital setting. The AI program continuously runs EKGs to continuously monitor a patient.

一种仿生3D打印水凝胶支架及其制备方法与应用

Resumen de: CN122624750A

本发明公开了一种仿生3D打印水凝胶支架及其制备方法与应用，属于医疗器械技术领域。该仿生3D打印水凝胶支架包括3D打印水凝胶支架和在3D打印水凝胶支架表面的仿贻贝催化涂层；3D打印水凝胶支架的生物墨水包括甲基丙烯酰化明胶、钙离子预交联海藻酸钠、负载STING激动剂的树突状细胞来源外泌体以及甲基丙烯酰化修饰的成骨生长肽；仿贻贝催化涂层由聚多巴胺层和负载在聚多巴胺层表面的多巴胺‑锰金属多酚网络纳米酶共同构成。通过各组件协同作用，有效解决了现有支架缺乏时序性治疗机制的技术问题，实现了骨转移肿瘤治疗中肿瘤清除与骨缺损修复的双重效果。

视频喉镜与患者电子病历的集成

Resumen de: WO2025117821A1

The technology relates to incorporating video laryngoscope data into the electronic medical record (EMR) of a patient. An example intubation system includes a patient terminal, a wireless hub, and a video laryngoscope. In an example method, the patient terminal accesses the electronic medical record of the patient; and receives, from the wireless hub wirelessly coupled to a video laryngoscope, intubation data generated by the video laryngoscope during an intubation procedure of a patient. The intubation data includes video data captured by the video laryngoscope and metadata for the video data generated by the video laryngoscope. The patient terminal then concurrently displays at least a portion of the intubation data with fillable fields of the electronic medical record; receives at least one interaction with the electronic medical record during the concurrent display; and stores the electronic medical record based on the at least one interaction.

バイオ複合材料組成物を作製および使用する方法

Resumen de: WO2025035104A2

Disclosed herein are methods of making and using biocomposite compositions comprising at least a polymeric component and a fiber component.

一种基于灯笼状柔性阵列的结肠电生理监测系统及肠炎智能评估方法

Resumen de: CN122604383A

0001 本发明公开了一种基于灯笼状柔性阵列的结肠电生理监测系统及肠炎智能评估方法，包括：柔性电极阵列，包含多个电极点并经激光切割形成若干纵向条带；可充气球囊导管，柔性电极阵列卷绕并固定于球囊外表面，在球囊充盈状态下，纵向条带被径向撑开，整体呈灯笼状，使各电极点从多角度共形贴附于结肠壁；信号采集模块，用于获取多通道结肠电生理信号；信号分析模块，用于进行多维分析，得出结肠健康程度的初步判断；再结合机器学习模型输出结肠炎症严重程度分级结果。本发明能稳定贴合结肠黏膜，并实现高质量监测结肠电生理信号，通过解析提取到的肠电信号多维特征识别肠道炎症，并与人工智能结合实现结肠炎症程度自动评估。

适用于脑卒中患者的手功能康复评估系统及其训练方法

Nº publicación: CN122604402A 21/08/2026

Solicitante:

华中科技大学

Resumen de: CN122604402A

本发明属于医疗康复相关技术领域，其公开了一种适用于脑卒中患者的手功能康复评估系统及其训练方法，系统包括：数据接收模块，用于接收患者执行上肢运动功能评估设定动作时的上肢多模态时序数据；特征融合模块，用于对数据进行特征提取后再融合，得到时空融合特征矩阵；肌肉协同量化模块，用于基于手臂肌电数据提取协同模式相似度、肌肉协同耦合度、激活时序同步性；运动协同量化模块，用于基于运动学数据提取运动协同耦合度；输入特征构建模块，用于将、、、与时空融合特征矩阵进行拼接得到输入特征矩阵；神经网络预测模块，用于根据输入特征矩阵实现患者手功能康复程度的预测。基于以上系统，可以实现脑卒中患者手功能康复的自动化评估。