Alerta

An abrasion-resistant coating for 3D printed metal implants and a 3D printed metal implant with such abrasion-resistant coating

SYSTEMS AND METHODS FOR ORTHODONTIC APPLIANCE PRODUCTION

Resumen de: WO2024199274A1

The present disclosure provides systems and methods for orthodontic appliance production. The methods may include determining a baseline thickness of an orthodontic appliance for orthodontically treating teeth of a target subject. The methods may include, for each local point on the teeth of the target subject, determining a movement path of the local point from an initial location of the local point to a target location of the local point. The methods may also include, for each local point on the teeth of the target subject, determining, based on the movement path and the baseline thickness, a target thickness of the orthodontic appliance corresponding to the local point. The methods may further include directing a three-dimensional (3D) printer to integrally produce, based on the target thickness of the orthodontic appliance at each local point, the orthodontic appliance.

A method of manufacture of a custom-made vibrator and a product obtained in such way

Resumen de: CZ2025251A3

Způsob výroby vibrátoru na míru zahrnuje využití softwarového programu uzpůsobeného k vytvoření 3D modelu na základě instrukcí zadaných zákazníkem, kde tento program obsahuje algoritmus, kterým je vytvořen 3D model vibrátoru tak, že výsledný výrobek odpovídá designu vytvořenému zákazníkem, přičemž tento program obsahuje nabídku pro tvorbu základního tvaru budoucího vibrátoru a jeho hlavních částí, kde zákazník může upravovat parametry pro tvorbu 3D modelu určeného k výrobě vibrátoru. V dalším provedení je softwarový program navíc uzpůsoben k vytvoření 3D modelu podle předlohy dodané zákazníkem, kde tento program obsahuje databázi profesionálně vytvořených 3D modelů, kde profesionálně vytvořenými 3D modely se rozumí soubor nejméně 20 vysoce detailních 3D modelů, získaných mnohonásobným 3D skenováním jednoho vzoru v co nejvyšším rozlišení 3D skeneru, přičemž tyto 3D modely reprezentují vzájemně nejrůznorodější předlohy, přičemž software obsahuje algoritmus s parametry k nalezení co nejvyšší míry shody zákazníkem dodané předlohy s profesionálním 3D modelem, přičemž algoritmus zanedbává absolutní rozměry předlohy a řídí se pouze mírou shody celkového tvaru, přičemž algoritmus porovnává shodu na základě určených parametrů.

CUSTOMIZED ADAPTIVE OBJECTS MADE BY ADDITIVE MANUFACTURING

Resumen de: WO2024199765A1

The field of the DISCLOSURE lies in adaptive objects and materials for implementation in textiles, ear buds, wearables and smart clothing. The present disclosure relates to adaptive devices or fabrics, comprising shape memory polymer(s) and optionally thermochromic pigment(s), wherein the device or fabric is obtained by fused deposition molding and has different states it reversibly changes in between depending on heating. The present invention further relates to methods of producing said adaptive devices or fabrics. The present disclosure also relates to the use of said adaptive devices or fabrics, in particular, their use for customizable ear buds, semi-woven textiles, parts of smart textiles, wearables and/or gaming gloves and suits. The present disclosure also relates to an ear bud or hearing aid as well as to an adaptive semi-woven 3D printed textile or clothing item.

INSTRUMENT FOR OPHTHALMIC SURGERY

Resumen de: WO2024175367A1

Instrument comprising: a. forceps (1) with an active end (1d) and a sleeve (2) receiving the forceps (1) with sliding, b. a central body (3) with a first, proximal end (3p) integral with a handle (4) and a second, distal end (3d) to which is fixed a first end (1p) of the forceps, opposite the active end (1d) of said forceps (1), c. an actuator (5) formed by a set of levers (6) extending around the central body (3) and having first ends (6p) connected to the central body (3) and second ends (6d) joined by a socket (7) to which the sleeve (2) is fixed, the levers (6) being elastically deformable between a first, deactivated position of the forceps (1), in which position the active end (1d) of the forceps (1) is open and projects from the sleeve (2), and a second, activated position, in which the sleeve (2) exerts a force on the active end (1d) of the forceps (1), forcing the closure of the active end (1d) of the forceps (1), wherein the central body (3), the actuator (5) and the socket (7) are a one-piece component.

PERSONALIZED SUPPORT DEVICE FOR MECHANICALLY AFFECTING A PULSATING ORGAN'S DYNAMIC BEHAVIOR

Resumen de: WO2024176233A1

A support device for a pulsating organ is comprised of a structure formed at least partially of one or more polymers. The structure is configured to transition, in response to a stimulus, between a placement shape, in which the support device is dimensioned larger than the dimensions of the organ, and a treatment shape, in which the support device provides therapeutic support to the organ; wherein the treatment shape is smaller than the placement shape. Preferably, the polymers are shape memory polymers. The support device may be manufactured in an initial shape in which the one or more shape memory polymers are in their permanent shapes, and the placement shape is larger than or equivalent to the initial shape. Optionally, the stimulus is application of an aqueous medium. Embodiments of support devices may be used for treatment of heart failure with reduced ejection fraction and with preserved ejection fraction.

METHOD AND SYSTEM OF CREATING A REPLICA OF AN ANATOMICAL STRUCTURE

Resumen de: MA65160A1

Creating a replica of an anatomical structure. In one embodiments a method includes: accepting pictures of the anatomical structure of a subject; creating an object file that contains an initial model of an outside surface of the anatomical structure; cutting the initial model to a predetermined exterior shape circumscribing the anatomical structure to create a positive model; creating a negative model from the positive model; placing a stem tool object on an outside surface of the negative model in relationship to an orifice, thereby creating a final negative model; placing a zeroing and angling object to align the negative model to a predetermined angle; placing a base tool object by coupling the base tool object to the outside surface; printing, by way of a three-dimensional printer, the final negative model to create a negative mold; and casting the replica of the anatomical structure using the negative mold.

POLYMERIZABLE POLYURETHANES AND COMPOSITIONS CONTAINING THE SAME FOR USE IN 3D PRINTABLE DENTAL MATERIALS

Resumen de: US2024352179A1

The present disclosure provides curable compositions comprising one or more of photo-polymerizable urethane prepolymers having alternating hard and soft blocks, as well as polymeric materials formed from the curable compositions. Further provided herein are methods of producing the compositions and using the same for the fabrication of medical devices, such as orthodontic appliances.

ADJUSTING AN ARRANGEMENT OF THREE-DIMENSIONAL DIGITAL TOOTH MODELS

Resumen de: US2024346788A1

Disclosed is a computer-implemented method for adjusting an arrangement of a plurality of three-dimensional digital tooth models for a dental restoration. A three-dimensional digital teeth model comprising the plurality of the three-dimensional digital tooth models is received. A first input is received selecting one or more of the three-dimensional digital tooth models. A second input is received defining a modification of the selected one or more three-dimensional digital tooth models. The selected one or more three-dimensional digital tooth models are modified according to the second input. While the selected one or more three-dimensional digital tooth models are modified according to the second input, adjustments of a geometric form of the selected one or more three-dimensional digital tooth models are automatically calculated and applying. Furthermore, adjustments of a set of remaining three-dimensional digital tooth models of the three-dimensional digital teeth model depending on the modification of the selected one or more three-dimensional digital tooth models are automatically calculated and applied. The resulting adjusted three-dimensional digital teeth model is provided for manufacturing the dental restoration.

WATER BOLUS WITH WATER VOLUME FLOW CONTROL

Resumen de: EP4670690A1

Water bolus (200) for covering part of an outer body surface of a body part, the water bolus comprising:- a flexible cover (202) for forming at least part of a container for containing a liquid; and- an insert (100) provided inside the flexible cover,wherein the insert is formed by interconnected struts (102) which form an open structure through which a liquid can flow.

兼具多孔结构与生物活性的丝蛋白骨钉制备工艺

Resumen de: CN121221862A

本发明公开了兼具多孔结构与生物活性的丝蛋白骨钉制备工艺，具体涉及生物医学工程技术领域，包括以下步骤：S1：提供丝蛋白原料，通过脱胶、溶解及纯化处理制备再生丝蛋白溶液；S2：将步骤S1所得丝蛋白溶液与致孔剂均匀混合，制备具有适宜黏度的混合浆料；S3：将步骤S2所得混合浆料转移至三维打印设备中，依据预设的骨钉三维模型进行挤出打印。本发明所述的兼具多孔结构与生物活性的丝蛋白骨钉制备工艺，通过三维打印技术与致孔剂的协同作用，制备出具有相互贯通多孔结构的丝蛋白骨钉，整体孔隙率为60%至85%。该多孔结构有效改善了传统盐溶致孔等方法形成的孔道连通性差的问题，有利于细胞迁移、血管长入和营养物质传输，从而加速骨缺损修复过程。

一种3D打印掺铜磷酸三钙梯度复合骨支架及制备方法

Resumen de: CN121221843A

本发明属于骨缺损修复治疗技术领域，尤其涉及一种3D打印掺铜磷酸三钙梯度复合骨支架及制备方法，骨支架包括：若干结构单元，阵列形成骨支架；骨支架的材质包括金属铜离子材料、磷酸三钙、光敏树脂和光引发剂，骨支架沿既定方向顺序划分为三个区域，三个区域的铜离子浓度逐渐减小，以使得骨支架在患者体内根据患者的恢复周期释放的铜离子浓度逐渐减小；骨支架的壁厚包括非梯度结构和梯度结构。本发明的骨支架能够改变金属铜离子在不同阶段的释放浓度，以满足骨缺损修复早期阶段的抗菌要求、中期阶段的促血管要求以及后期的成骨和骨重塑要求。

取栓支架系统及其制备方法、应用

Resumen de: CN121221214A

本申请公开了一种取栓支架系统及其制备方法、应用，属于医疗器械技术领域，取栓支架系统包括膨胀支架、微导管和溶栓药物，方法包括：根据目标血栓的造影数据，确定溶栓药物的目标剂量；根据溶栓药物的目标剂量，确定溶栓药物的第一目标打印参数；按照第一目标打印参数，通过3D打印在膨胀支架上形成含有溶栓药物的药物层，将膨胀支架置于微导管内，制得取栓支架系统。本申请解决了常规取栓过程溶栓药物无法根据血栓实际情况实现精准释放的技术问题。

一种负载酸马奶来源外泌体的ROS响应广谱抗菌3D打印水凝胶及其制备方法和应用

Resumen de: CN121221840A

本发明提供了一种负载酸马奶来源外泌体的ROS响应广谱抗菌3D打印水凝胶及其制备方法和应用，属于烧伤药物技术领域。本发明用纳米银对酸马奶来源外泌体（K‑Exo）进行改性，制备成具有抗菌功能的新外泌体K‑Exo‑Ag。用丝素肽(GAGAGS)2自组装成纳米微晶的特性，将K‑Exo‑Ag包裹起来，制备ROS响应的载药微晶，将其负载到可以3D打印的甲基丙烯酸酯化丝素蛋白水凝胶中，用于治疗大面积深度烧伤难愈合创面治疗。本发明提供的水凝胶具有广谱抗菌作用，可以有效杀死白色念珠菌、铜绿假单胞杆菌和金黄色葡萄球菌；同时具有广谱抗氧化、主动调控免疫系统和ROS响应功效，对大面积深度烧伤难愈合创面有着良好的治疗效果。

水凝胶墨水、水凝胶及其用途

Resumen de: WO2024237865A1

This disclosure concerns a hydrogel ink comprising lipid particles, polynucleotides loaded within the lipid particles and a bioink. In one embodiment, the lipid particles comprise extracellular vesicles. The disclosure also concerns the hydrogel thereof, and its use in treating a neural disease or condition, or regenerating a soft tissue.

一种多材料3D一体式打印头盔及其制造方法

Resumen de: CN121221338A

本申请公开了一种多材料3D一体式打印头盔及其制造方法，涉及头形矫正领域，包括下盔套，所述下盔套的顶部固定连接有第一侧盔板和第二侧盔板，所述第一侧盔板和第二侧盔板的表面设置有第一调节缝隙，所述第一调节缝隙的外侧设置有第一卡带，所述第一卡带与第二侧盔板的表面固定连接，且第一卡带的一端设置有相适配的第一卡扣座。本申请可通过第一侧盔板和第二侧盔板表面设置的第一调节缝隙、第二调节缝隙，配合第一卡带、第二卡带及卡扣座，能够根据佩戴者头部尺寸进行调整，通过卡带在调节缝隙处的拉伸与卡扣固定，可实现头盔横向尺寸的动态适配，确保不同头围的使用者都能获得贴合稳固的佩戴体验，有效避免因头盔过松或过紧影响矫正效果。

一种基于光敏生物陶瓷的乳牙增材制造成型工艺

Resumen de: CN121221305A

本发明公开了一种基于光敏生物陶瓷的乳牙增材制造成型工艺，涉及陶瓷乳牙制造技术领域，包括以下步骤：采用口腔扫描仪采集患儿牙颌三维数据，生成乳牙修复体三维数据模型并导出STL格式乳牙修复模型；采用光敏液态生物陶瓷复合材料，经DLP光固化3D打印成初坯，再经蓝光三阶段再固化得坯体。本工艺中可精准提取相邻健康乳牙的形态特征，并根据患儿年龄自动匹配牙冠高度修正系数，有效补偿乳牙未完全萌出的尺寸偏差，确保修复体尺寸误差较小，同时对颌牙实际数据调整修复体咬合面形态，使咬合接触面积占比较高，并预留咬合缓冲空间，避免局部受力过大，显著提升咀嚼舒适度与修复体耐用性。

用于生产三维丝网印刷工件的设备

Nº publicación: CN121240944A 30/12/2025

Solicitante:

埃克森蒂斯知识股份有限公司

Resumen de: WO2024188676A1

The invention relates to an apparatus for producing three-dimensional screen-printed workpieces, in particular a 3D screen printing installation, said apparatus comprising: a printing device for the layer-by-layer production of at least one screen-printed workpiece in a plurality of printing operations; and a transport device for the automated transport of at least one screen-printed workpiece and/or a workpiece carrier to and/or from the printing device, the transport device having a support portion for at least interlockingly receiving a workpiece carrier.