Bioimpresión 3D

SYSTEM AND METHOD FOR PRODUCING PHARMACEUTICAL OBJECTS VIA 3D PRINTING

Resumen de: US20260069503A1

Method for 3D printing, comprising the following steps: providing a packaging (2′) having at least one recess (3′) for receiving a product (1′), wherein the shape of the recess (3′) corresponds at least in part to the shape of the product (1′) and wherein the recess (3′) forms a protuberance at the other side of the packaging (2′); providing a 3D printer with a print base (5′) having at least one recess (6′) for receiving the protuberance formed by the recess (3′) of the packaging (2′); inserting the packaging (2′) in the print base (5′) such that the protuberance formed by the recess (3′) of the packaging (2′) is received by the recess (6′) of the print base (5′); filling a print head (7′) of the 3D printer with at least one material for printing the product (1′); 3D printing the product (1′) inside the recess (3′) of the packaging (2′), wherein the part of the recess (3′) corresponding to the shape of the product (1′) serves as the mold and print support, resp., for those layers of the product (1′) which are 3D printed first. The method is performed with a system for 3D printing, comprising a packaging (2′) having at least one recess (3′) for receiving a product (1′), wherein the shape of the recess (3′) corresponds at least in part to the shape of the product (1′) and wherein the recess (3′) forms a protuberance at the other side of the packaging (2′); and a 3D printer with a print head (7′) and a print base

METHODS OF FABRICATING LASER-SINTERED CARBOHYDRATE MATERIALS AND COMPOSITIONS AND USES THEREOF

Resumen de: US20260070282A1

A composition useful in forming a structure in the form of a substantially interconnected vascular network. The composition includes a powder including a carbohydrate powder and an anti-caking agent, where the powder: has a granular form, and has a specific energy of less than 6 millijoules per milliliter (mJ/mL).

SUCTION TOOTHBRUSH AND RELATED METHODS

Resumen de: US20260069028A1

A suction toothbrush includes a handle defining an opening, a toothbrush head including internal channels, a seal with a distal end received within the toothbrush head and a proximal end coupled to the handle through the opening thereof, and a connector extending through the annular body of the seal. The connector includes a main body having a distal end disposed within the internal conduit of the toothbrush head and a proximal end extending into the handle through the top opening thereof, and a vibration motor housing offset from the proximal end of the main body. A waste reservoir for a suction toothbrush includes a lid, a basin defining a sump for waste material, and a gas-permeable membrane disposed between the lid and the basin that defines central inlet opening. A 3-D printing method for suction toothbrush heads.

SYNTHETIC BONE GRAFTS AND METHODS FOR THEIR PREPARATION

Resumen de: US20260069746A1

The present invention provides methods for the preparation of synthetic bone grafts which are made of a composition comprising two matrixes, one ceramic including interlocked CDHA crystals, and another of one or more binder(s), the two matrixes being admixture. The method comprises the preparing of an ink composition, the 3D-printing, and the hardening of the binder and ceramic components, in this order.The resulting bone grafts, which are characterized by including the two matrixes in admixture, shows improved mechanical properties as well as excellent biological properties.

Tibia-Implantat

Resumen de: DE102024126035A1

Die Erfindung betrifft ein Tibia-Implantat (2) für Gelenkersatz, welches aus Metalllegierung in einem additiven Fertigungsverfahrenhergestellt ist, mit einem Plateauabschnitt (4) und mit einem auf der tibiazugewandten Seite (8) des Plateauabschnitts (4) vorspringenden und sich davon in einer axialen Richtung (10) wegerstreckenden zapfen- oder kielförmigen Ankerabschnitt (6),; erfindungsgemäß wird vorgeschlagen, dass der Plateauabschnitt (4) auf seiner tibiazugewandten und mit Tibiaknochengewebe in Kontakt gelangenden Seite (8) eine dreidimensional poröse offenporige Oberflächenstruktur (14) mit in der axialen Richtung (10) hintergreifbaren Brücken, Stegen oder Wandbereichen aufweist, wobei die offenporige Oberflächenstruktur (14) eine erste Rauigkeit aufweist, und dass der Ankerabschnitt (6) anschließend an den Plateauabschnitt (4) in einem ersten axialen Ankerbereich (20) umfangsseitig eine in einer radialen Richtung (12) hinterschnittfreie, das heißt von hintergreifbaren Brücken und brückenbildenden Stegen freie Oberflächenstruktur (28) mit einer zweiten Rauigkeit aufweist, die geringer ist als die erste Rauigkeit, und dass der Ankerabschnitt (6) in der axialen Richtung (10) anschließend an den ersten axialen Ankerbereich (20) einen zweiten axial frei endenden axialen Ankerbereich (22) mit einer glatten Oberfläche aufweist.

PATIENT INTERFACE

Resumen de: AU2026201217A1

A patient interface comprises a support structure and a seal-forming structure. The support structure is arranged to support the sealing portion and is configured to connect to the frame. The sealing portion comprises textile and is attached to the support structure along an outer perimeter of the sealing portion such that in use the sealing portion may be in tension due to reactive stress of the support structure and/or a resilient stretch characteristic of the textile such that the sealing portion exerts a force against the patient’s face. eb e b

SYSTEM AND METHOD FOR PERFORMING QUALITY ANALYSIS FOR MULTIDIMENSIONAL PRINTING

Resumen de: US20260070279A1

A system for performing quality analysis for multidimensional printing. The system includes a multidimensional printer, wherein the multidimensional printer comprises a printing head, a printing surface, an axis system and a scale, wherein the scale is arranged to measure weight applied on the printing surface; and a control unit operatively coupled to the multidimensional printer. The control unit is configured to control the printing head to extrude a printing material, to produce a printed object on the printing surface, obtain, from the scale, a weight of the printed object, and store the weight of the printed object in a memory associated with the control unit, compare the weight with a reference weight of the printed object, and control the printing head to stop extrusion of the printing material when the weight is equal to or exceeds the reference weight.

ARTICLES INCLUDING A MICROSTRUCTURED CURVED SURFACE, TOOLING ARTICLES, AND METHODS

Resumen de: US20260070777A1

The present disclosure provides a microstructured article including a thermoplastic polymer shaped to have a curve. At least a portion of the curve includes a microstructured surface of utilitarian discontinuities and the microstructured surface includes peak structures and adjacent valleys. The peak structures and the curve are formed of a single piece of the thermoplastic polymer. A method of making the microstructured articles is also provided including a) obtaining a tool shaped to include at least one of a protrusion or a concavity; b) disposing a microstructured film on at least a portion of the tool including the protrusion and/or the concavity; and c) thermoforming a single piece of thermoplastic polymer onto the tool to form a microstructured article shaped to include a curve. The curve is an inverse of the protrusion or the concavity of the tool.

TWO-PHASE 3D PRINTING OF BIOCOMPATIBLE STRUCTURES

Resumen de: US20260069744A1

A method of printing a hydrogel scaffold is provided which includes providing a container containing an ink and a liquid that is immiscible with the ink; applying light from a light source to the ink to form a portion of the hydrogel scaffold; and applying light from a light source one or more additional times to produce one or more additional portions of the hydrogel scaffold.

TIBIA IMPLANT

Resumen de: US20260069422A1

A tibia implant for joint replacement has a plateau section and an anchor section projecting from a tibia-facing side of the plateau section. The anchor section is insertable into a channel in a tibia bone. The plateau section has a first surface structure that is a porous open-pore surface structure with bridges, webs or wall regions that can be gripped from behind in the axial direction on the tibia-facing side that comes into contact with tibia bone tissue. The open-pore surface structure has a first roughness. The anchor section is connected to the plateau section in a first axial anchor region on the circumferential side has a surface structure with a second roughness that is lower than the first roughness. The anchor section has a second axially free-ending axial anchor region with a smooth surface in the axial direction adjacent to the first axial anchor region.

DENTAL APPLIANCES WITH INTERPROXIMAL ENGAGEMENT STRUCTURES

Resumen de: US20260069385A1

Dental appliances and associated systems are provided. In some embodiments, a dental appliance includes a shell configured to receive a plurality of teeth, the shell having a sidewall and an interproximal engagement structure extending from the sidewall into a space of an interproximal region between a first tooth and a second tooth of the plurality of teeth. The interproximal engagement structure can be configured to contact the first tooth and the second tooth concurrently. The interproximal engagement structure can be larger than the space of the interproximal region, such that the contact causes deformation of one or more of the interproximal engagement structure or the sidewall.

MULTI-MODAL PATIENT-SPECIFIC SURGICAL GUIDES

Resumen de: US20260069290A1

A surgical device includes a first body component including at least one insert embedded therein and a second body component including a patient-specific surface. The first body component includes a first material and the at least one insert includes a second material. The first body component defines at least one first hole and the second body component defines at least one second hole. The second body component is configured to be coupled to the first body component such that the at least one first hole and the at least one second hole are aligned when the first body component is coupled to the second body component to define at least one continuous fixation hole sized and configured to receive an elongate fixation device at a predetermined location.

MEDICAL DEVICES AND RELATED METHODS

Resumen de: US20260069260A1

A medical device includes an operating member, a hub, and an end effector. The operating member includes an actuation portion. The hub includes a channel receiving the actuation portion of the operating member. The actuation portion of the operating member moves within the channel. The end effector is movable between a closed configuration and an open configuration. Distal extension of the operating member transitions the end effector to the open configuration, and proximal retraction of the operating member transitions the end effector to the closed configuration. The medical device is formed through an additive manufacturing process.

AUGMENTED REALITY SCANNING INTERFACE FOR GENERATING PERSONALIZED 3D PRINTED CASTS

Resumen de: US20260069145A1

A method of generating a 3D model of a body part includes scanning the body part with a 3D scanner; during the scanning step, generating, with an augmented reality user interface, an augmented reality view of said body part, wherein the augmented reality view differentiates between portions of the body part that have already been scanned and portions that have not yet been scanned; with guidance from the augmented reality view, completing the scan; and generating the 3D model based on data received from the scan. The augmented reality view is displayed on a practitioner-facing screen incorporated into the scanning device. The method may further include imaging the body part with a thermal imager and overlaying thermal scanning data onto the 3D model to thereby generate a distribution map of thermal sensitivity on the 3D model. The design is then generated with holes situated to maximize thermal comfort.

MOLECULARLY CLEAVABLE BIOINK FORMULATION

Resumen de: US20260071187A1

A bioink formulation for digital light processing bioprinting comprising a mixture of a biocompatible cleavable polymer precursor, a biocompatible non-cleavable polymer precursor, and a photoinitiator is described. Three-dimensional (3D) objects prepared using these bioink formulations are also described. In addition, a method of 3D bioprinting is described. The method includes providing a bioink formulation in a 3D bioprinter vat; repeatedly photoactivating the biocompatible photoactive polymer precursors in the 3D bioprinter vat on a build plate immersed in the vat to form a 3D bioprinted object comprising polymers having a series of predefined shapes across the vertical direction based on a set of sliced images; and treating the 3D bioprinted object with an agent that cleaves chemical bonds within the cleavable polymer.

DESIGN METHOD OF TRANSPARENT ORTHODONTIC DEVICE AND ATTACHMENT FOR ORTHODONTICS

Resumen de: EP4706587A1

The method for designing a transparent orthodontic appliance and attachment for tooth alignment according to the present invention has been devised to solve the above technical problems. It is a method for designing an orthodontic appliance using a computer, comprising: a step (S01) of designing the shape of an attachment to be affixed to the surface of a tooth model; a step (S02) of designing the inner surface shape of the transparent orthodontic appliance corresponding to the attachment designed in step S01; and a step (S03) of outputting the transparent orthodontic appliance by means of a 3D printer. The attachment comprises: two pressure surfaces (101) formed to face each other; two inclined surfaces (201) formed to be inclined toward each other while contacting the two pressure surfaces (101); a top surface (301) contacting the edges of the two pressure surfaces (101) and the two inclined surfaces (201); and an attachment surface (401) affixed to the surface of a tooth. This configuration serves as the technical means for solving the problem.

SEMICRYSTALLINE SULFUR CONTAINING POLYMERS FOR ORTHODONTIC APPLICATIONS

Resumen de: US2025009476A1

The present disclosure provides polymeric materials comprising semicrystalline sulfur-containing polymers, methods and curable compositions for making the same, and orthodontic appliances made from said polymeric materials.

METHOD FOR MANUFACTURING ORTHODONTIC DEVICE BY USING INSERTION PATH

Resumen de: EP4706586A1

The present invention relates to a program for designing an orthodontic appliance. The method comprises: displaying, on a screen, the insertion path for determining the insertion direction of the appliance (S01); designating a tooth targeted for the insertion path setting (S02); setting the insertion path for the designated tooth in an arbitrary direction (S03); displaying, on the screen, undercuts of each tooth caused by the set insertion path (S04); calculating and storing depth values of the undercuts for each tooth (S05); and calculating and storing the total sum of undercut volumes for each tooth according to the insertion path (S06).

RADICALLY POLYMERISABLE COMPOUND AND COMPOSITION

Resumen de: WO2024227533A1

The invention relates to a radically polymerisable compound represented by a structure of formula 1: PG-Sp-PCA-Sp- OG (O) NH-K-NHC (O) O-Sp-PCA-Spn-PG (formula 1), wherein PG = in each case independently selected from a radically polymerisable group, R1 = selected from hydrogen, a C1-C8 alkyl group, an aryl group and an araliphatic group having C6-C8 carbon atoms, R2 = selected from hydrogen, a C1-C4 alkyl group; Sp = in each case independently of one another a spacer group selected from unbranched and branched alkylene with C1-C19 carbon atoms, which may additionally contain oxygen, sulfur and/or -OOC- in the carbon chain, or Sp is absent; PCA = in each case independently of one another a polycyclic group; K = an aliphatic acyclic, saturated or unsaturated unit having C1-C15 carbon atoms, an aliphatic cyclic, saturated or unsaturated unit having C3-C15 carbon atoms, or an aromatic or araliphatic unit having C6-C14 carbon atoms; n = 1 to 9. The invention also relates to a process for preparing such a compound, a radically polymerisable composition containing such a compound, the use thereof and a cured dental material.

一种防移位锁定加压接骨板及其制备方法

Resumen de: CN121622217A

本发明公开了一种防移位锁定加压接骨板及其制备方法，属于医疗器械技术领域。所述接骨板包括：具有解剖曲度的主体；设置在主体骨干对应区的梯度多孔结构区域，其孔隙率自中轴向两侧梯度降低，以优化力学匹配、促进骨长入；沿板体排列的多功能复合孔组，每组包含一个锁定孔和一个带倾斜加压滑道的动态加压孔；以及设于板体两端的T形定位槽与遍布骨接触面的微观防滑纹理构成的防移位锚定结构，确保术中瞬时定位与术后抗微动稳定。其制备方法基于患者医学影像进行参数化设计与有限元优化，并采用选区激光熔化技术一体成型。本发明有效解决了传统接骨板应力遮挡、术后移位与骨整合不足的临床问题，显著提升了固定效果与愈合质量。

一种三维水凝胶支架及其制备方法和骨修复应用

Resumen de: CN121623010A

本发明涉及医用生物材料技术领域，尤其涉及一种三维水凝胶支架及其制备方法和骨修复应用。所述三维水凝胶支架为通过若干水凝胶管搭建的层叠的、三维有序结构，每层包括平行间隔排列的多根水凝胶管，相邻两层的水凝胶管之间呈夹角，所述三维水凝胶支架的组分包括海藻酸钠；在三维水凝胶支架中，每根水凝胶管之间具有大孔，每根水凝胶管内部具有全连通微通道，每根水凝胶管的外表面和内表面都具有表面取向性纳米纤维结构。本发明的三维水凝胶支架能很好的应用于骨修复方面，并且本发明利用3D打印、不均匀的交联和拉伸干燥联合技术成功构建了三维水凝胶支架，制备工艺简单准确，易于操作，有利于工业推广和应用。

心电图机及心电图机的打印控制方法

Resumen de: CN121622054A

本申请实施例提供了一种心电图机及心电图机的打印控制方法，包括：打印机构，包括包含第一加热点和第二加热点在内的多个加热点；驱动机构，用于驱动目标纸张和打印机构相对移动；控制器，用于：根据第一心电波形数据控制打印机构在第一目标纸张打印至少部分以第一预定布局排布的第一心电图报告，第一加热点用以生成其中的第一基线；根据第二心电波形数据控制打印机构在第二目标纸张打印至少部分以第二预定布局排布的第二心电图报告，第二加热点用于以生成其中的第二基线；第一心电波形和第二心电波形分别位于第一预定布局和第二预定布局二者布局相同的区域，以显著减少部分加热点的加热次数，进而提升心电图机中打印功能模块的使用寿命。

一种3D打印颌骨生物支架

Resumen de: CN121622995A

本发明提供了一种3D打印颌骨生物支架，利用3D打印技术成功构建了负载颌骨BMSCs与牙髓dECM生物支架，同步满足颌骨缺损修复对机械支撑强度、生物活性微环境、成骨仿生诱导特性及免疫调控能力的核心需求。

一种用于制作后巩膜加固术垫片材料的取材模板及其制作装置

Resumen de: CN223979895U

本实用新型公开了一种用于制作后巩膜加固术垫片材料的取材模板及其制作装置，立体状态时，取材模板包括由中间的第一加固区和两侧的第一连接带构成的垫片立体模板，平面状态时，包括由所述垫片立体模板展开形成平板式结构的垫片平面模板，垫片平面模板包括中间的第二加固区和两侧的第二连接带，第二加固区上端轮廓为若干弧线光滑过渡连接并向上凸起的曲线，第二加固区下端轮廓为若干弧线光滑过渡连接组成并向上凸起曲线；第二连接带轮廓为若干曲线光滑过渡连接组成的长条形。本实用新型中3D打印系统根据不同患者的实际情况，准确制造出适合每一位患者的垫片模板，再根据该垫片模板制出垫片，提高了手术的效率，而且提高了垫片精度，保证手术质量。

Scanning and printing calibration tool

Nº publicación: USD1117772S 10/03/2026

Solicitante:

SHIM MI YOUNG [KR]
PARK JUNE BEOM [KR]
Shim Mi Young,
Park June Beom

Resumen de: JP2024160362A

To provide a dentition phantom model capable of precisely evaluating scanning accuracy of a scanner.SOLUTION: A dentition phantom model 100 includes a base layer composed of a first base layer 110 and a second base layer 120, and a dentition layer 130 disposed on the base layer and including a tooth model, where the tooth model is configured so that a shape observed from one direction is different respectively from shapes observed from the remaining other directions.SELECTED DRAWING: Figure 1aa