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110
resultados
Última actualización
04/08/2025 [07:04:00]
Resumen de: US2025243452A1
The present invention provides a method and system for fabricating complex human tissues by integrating bio-electrospraying, cell electrospinning merged with 3D multi material microfluidic bioprinting, and future additions of magnetic and acoustic levitation technologies. The fabricated tissues serve as an alternative to animal testing in drug discovery processes, aiding in the prediction of human physiological responses to various drug compounds.
Resumen de: AU2025205378A1
21894047_1 (GHMatters) P119307.AU.2 The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D print- ing. The system comprises a 3D printing machine (2) with a me-5 chanical system (3) movable in one or more directions, at least one print head (5) with a nozzle (37) being movable by the me- chanical system (3) and a base system (4) carrying a print base (6) for receiving a prepared mixture (27) applied by the print head (5). The system comprises at least one carrier (35) for 10 holding a cartridge (28).Printing can be done on formatted print locations (49) on the base (6). The invention further relates to a method for producing pharmaceutical objects, comprising the steps of providing at least one pharmaceutical substance in at least one cartridge, placing the cartridge in a carrier, estab-15 lishing a fluid connection between a cartridge and a print head, such that the pharmaceutical substance may leave the print head through the print head nozzle, moving the print head nozzle ac- cording to a 3D print program and dispensing the pharmaceutical substance to a print base. 20 (Fig. 24) The invention relates to a system for producing pharmaceutical objects, such as tablets, granules and capsules, via 3D print- 5 ing. The system comprises a 3D printing machine (2) with a me- chanical system (3) movable in one or more directions, at least one print head (5) with a nozzle (37) being movable by the me- chanical system (3)
Resumen de: US2025243128A1
The present invention relates to methods for preparing ceramic devices having a surface that has been activated to enhance properties including strength, porosity, and bioactivity. Activation may include forming a gel layer on the surface of a ceramic device using an alkali solution and modifying the surface using a modifying material. The invention further relates to ceramic devices prepared by the methods and methods of using the devices.
Resumen de: US2025243465A1
Described are methods for producing multi-layered tubular tissue structures, tissue structures produced by the methods, and their use.
Resumen de: US2025243447A1
A hybrid microextrusion pick-and-place 3D printing process enables fabrication of 3D-printed well plate-integrated piezoelectric cantilever sensors for monitoring properties and composition of tissue culture models. 3D-printed piezoelectric cantilever sensors exhibit multiple resonant modes across the 1-150 kHz frequency range. The ability to control cantilever frequency response (i.e., mode locations and types) was demonstrated by variation in the 3D-printed anchor geometry through corresponding changes in tool path and microextrusion process parameters. 3D-printed piezoelectric cantilever sensors facilitated in situ monitoring of cell culture media density and viscosity. This work presents an advance in the fabrication of cantilever sensors through the use of hybrid 3D-printing and pick-and-place processes that improves sensor reproducibility and enables novel control over anchoring of piezoelectric components and sensor integration with both 2D and 3D cell culture models, particularly 3D-bioprinted tissue constructs and microphysiological systems.
Resumen de: CN119997989A
A hydrogel string for encapsulating a biological material is provided. A hydrogel string has a thiol-ene cross-linked polymer having a first side chain functionalized backbone polymer functionalized with an activated olefin that is cross-linked with a free or protected thiol-containing group present on a second side chain functionalized backbone polymer. The biological material is encapsulated in a thiol-ene cross-linked polymer.
Resumen de: WO2024059942A1
It is provided a cell macroencapsulation device for implanting cells in a recipient comprising cells encapsulated in a porous membrane, wherein the porous membrane consists of a sugar network coated with a polymeric solution comprising porogen, which can be used as a graft to transplant islets while protecting the graft from the immune system as well as providing enhanced convection and diffusion to ensure long-term cell survival and physiological insulin delivery.
Resumen de: CN119968177A
The present disclosure encompasses systems, compositions, and methods for use in vivo, including for enhancing soft tissue in an individual. The systems, compositions, and methods may utilize a three-dimensionally printed scaffold comprising at least a polymeric scaffold and an extracellular matrix component, including an extracellular matrix component contained on the scaffold. The polymer scaffold may include specific unit cell structures having a specific design and a pattern of alternating configurations of unit cell structures.
Resumen de: US2024100775A1
Systems, methods, and devices for additive manufacturing are provided. In some embodiments, a method includes: coupling a plurality of build platforms to a carrier; forming a plurality of 3D objects on the plurality of build platforms using an additive manufacturing process, where each build platform receives at least one 3D object thereon; removing the plurality of build platforms from the carrier; performing post-processing of the plurality of 3D objects while the 3D objects remain on the respective build platforms; and separating the plurality of 3D objects from the respective build platforms.
Resumen de: WO2024062324A1
A system for creating a tissue interface. The system includes a scanner, at least one processor, and a memory. The scanner is configured to scan a tissue site and generate a signal corresponding to a topography of the tissue site. The at least one processor is configured to receive the signal corresponding to the topography of the tissue site and to receive user input at a user interface identifying a therapy to be applied at the tissue site. The memory is coupled to the at least one processor and is configured to store instructions that when executed by the at least one processor in response to receiving the signal corresponding to the topography of the tissue site cause the system to transform the signal corresponding to the topography of the tissue site into a model site surface and generate a model tissue interface.
Resumen de: WO2024062369A1
Guide plate for the anatomical realignment of a plurality of fractured bone portions, comprising a back surface configured such as it can be distinctively coupled to the surface anatomy of the area of said plurality of fractured bone portions and characterized by a first plurality of holes placed on a first portion of the guide plate and a second plurality of holes placed on a second portion of the guide plate, wherein the first plurality of holes is misaligned with respect to the second plurality of holes.
Resumen de: CN120381355A
本发明公开了一种软硅胶‑硬塑料构成的包覆结构胆道支架，本发明包括防腐蚀内层、硬塑料内芯和包覆式生物相容性外层，防腐蚀内层为管状；硬塑料内芯包括若干个力学支撑结构环，各个力学支撑结构环沿胆道支架的轴向方向依次间隔固定套装在防腐蚀内层的外侧面，包覆式生物相容性外层包括若干个包覆式硅胶件，每个力学支撑结构环的外表面包覆有一个包覆式硅胶件，且每个包覆式硅胶件均一体成型于防腐蚀内层上。本发明可以提供与原生胆道相匹配的力学特性与生物相容性，能够并降低对胆道黏膜的刺激，承受胆汁腐蚀、减少细菌粘附、可长时间使用以及可以弯曲扭转以满足人体正常生理活动需求。
Resumen de: CN120381561A
本发明涉及医疗器械技术领域，尤其是涉及一种牙槽骨骨增量屏障膜及其制备方法。本发明提供的牙槽骨骨增量屏障膜包括通过3D打印技术制得的氧化锆膜；所述牙槽骨骨增量屏障膜包括牙槽嵴面、唇侧面和舌侧面，所述唇侧面和所述舌侧面位于所述牙槽嵴面相对的两侧；所述唇侧面和/或所述舌侧面上设置有固定孔，所述固定孔的总个数为至少两个；所述牙槽嵴面上设置有透气孔。本发明的牙槽骨骨增量屏障膜具有优异的机械性能和生物相容性，组织粘黏性低；能够更好的贴合患者牙槽骨缺陷处。
Resumen de: CN120383773A
本发明公开了一种骨骼来源羟基磷灰石制备3D打印油墨的方法，通过骨骼预处理、脱细胞、纳米化及复合油墨配制技术，实现天然HA的高效提取与打印应用，兼具环保性、情感价值及艺术创新。
Resumen de: US2024025122A1
A method for arranging support structures for an additive manufacturing process on a dental restoration, comprising the steps of detecting (S101) a flash line in a digital model of the dental restoration; and adding (S102) support structures to the digital model for supporting the dental restoration in the additive manufacturing process along the flash line.
Resumen de: CN120382643A
本发明属于生物3D打印技术领域，具体的说是一种生物3D打印培养一体化设备，包括：机体，所述机体内壁的顶部滑动连接有密封板，所述机体的内壁均匀设置有导杆，所述机体的内壁靠近密封板的一侧滑动连接有挡板；承托机构，所述承托机构安装在机体内壁的底部，所述承托机构的内壁与导杆的外壁相套接；注入机构，所述注入机构安装在机体内壁的上方，本发明通过设置承托机构，使夹持组件将培养皿固定在承载板的中轴处，并使夹持组件与对齐组件调整注射头的位置，随后进行注射，使打印与培养处于一个机体内完成，避免在注射完成后还需要人工移动培养皿，使细胞的环境发生变化导致难以培养，同时确保在培养过程中使用者可以拆卸注射机构进行清洗。
Resumen de: CN119894981A
An advanced fabricated interpenetrating polymer network (AM-IPN) is disclosed, comprising: a primary polymer network; a secondary polymer network, where the secondary polymer network is bound to the primary polymer network by one or more cross-links, where one or more of the primary polymer network, the secondary polymer network, and the one or more cross-links are printed using a synthetic bio-ink. Methods of making and using are also disclosed.
Resumen de: US2025206865A1
A curable composition which has high curability and high transparency, while exhibiting good adhesion to various base materials, and which is used in both an aqueous system and an organic system and is applied to UV curing and/or thermal curing; a coating agent composition, a bonding agent composition, an adhesive composition, an ink composition, an aqueous ink composition, an ink composition for three-dimensional modeling, an aqueous coating material composition, a sealing agent composition, a nail cosmetic composition, a dental material and a decorative coating agent, each of which contains this curable composition; and cured products and molded articles of these materials. A curable composition contains: (A) a water-insoluble multifunctional (meth)acrylamide; and (B) a polymerizable compound other than the component (A).
Resumen de: MX2024014120A
Aspects of the disclosure include a fabrication platform for supporting a bioprinted fiber structures during printing, patterning, and/or processing, comprising a frame with a plurality of posts for securing a cross-linkable fiber during printing thereof, and where a continuous length of the cross-linkable fiber is printed around a plurality of posts during the 3D bioprinting process. The fabrication platform enables the cross-linkable fiber to be suspended during one or more of printing, patterning, and/or processing. In this way, the bioprinted fiber structure comprises a uniform outer surface, and can be easily modified and/or further processed after printing and patterning are completed.
Resumen de: WO2024015237A1
The present disclosure provides a method of bioprinting a 3-D structure comprising one or more biologically-relevant materials on a super-hydrophobic surface. In one embodiment, the method comprises providing a composition having one or more biologically-relevant materials dispersed within a biocompatible medium. A pattern comprising a hydrophilic material is deposited on a defined area of the super-hydrophobic surface, wherein the pattern is modeled after a biological structure. The composition having the one or more biologically-relevant materials is then bioprinted atop the hydrophilic surface to form a 3-D structure, wherein the hydrophilic surface maintains the 3-D structure in a desired position or shape on the super-hydrophobic surface.
Resumen de: CN120360726A
本发明公开了一种基于数字化技术的治疗义齿制作方法，其包括：通过扫描获取患者的口腔数据及颌位关系，根据扫描获得的口腔数据及颌位关系设计上颌义齿和下颌义齿；通过3D打印制成上颌基托实体、上颌牙列实体、下颌基托实体和下颌前牙实体；用粘接剂将上颌牙列实体粘接在上颌基托实体上形成上颌义齿实体，用粘接剂将下颌前牙实体粘接在下颌基托实体上形成下颌义齿实体；向下颌基托实体上的凹槽中填充材料形成树脂平板；对树脂平板进行修正，直至上颌义齿实体与下颌义齿实体建立正确的咬合关系。本发明采用数字化设计与3D打印相结合的方式，制作流程短，能显著缩短治疗义齿的制作周期；且制成的治疗义齿实体和所设计的数字化治疗义齿的一致性高，减少了认为误差。
Resumen de: WO2023222193A1
The invention relates to a series (100) of devices for incrementally modifying the position of the teeth in a person (P), said series comprising at least two devices (10), the devices (10) each comprising at least one jaw device (11, 12), the at least one jaw device (11, 12) being designed in such a way that receiving regions of the jaw device (11, 12) can be placed on a dental arch of the upper jaw (OK, 5) or of the lower jaw (UK, 4) of the person (P), the devices (10) being designed such that, when worn according to a predefined order of said devices (10), they incrementally progressively modify the position of the teeth owing to mechanical interaction between the device and at least one tooth element. The at least one jaw device (11, 12) of the first device (10.1, 10.2) may carry, on its outer side, a first veneering element (N.I.1.2, N.IV.1.2) as a partial region of the first device (10.1, 10.2). The at least one jaw device (11, 12) of the second device (10. n) may carry, on its outer side, a second veneering element (N.I.1.n, N.IV.1.n) as a partial region of the second device (10). The first veneering element (N.I.1.2, N.IV.1.2) may be located at the same position as the second veneering element (N.I.1.n, N.IV.1.n) according to a dental notation. A receiving region of the first veneering element (N.I.1.2, N.IV.1.2) may have a different design and/or position than a receiving element of the second veneering element (N.I.1.n, N.IV.1.n), this difference being capable of cau
Resumen de: CN120365051A
本发明公开了一种双相生物活性组织修复支架及制备方法，包括以下步骤：步骤1：磷酸钙陶瓷粉体进行表面改性，得到改性后的磷酸钙陶瓷粉体；步骤2：将改性后的磷酸钙陶瓷粉体、铌酸钾钠压电陶瓷粉体、分散剂、光引发剂、光敏树脂充分混合均匀，球磨后得到光固化树脂浆料；步骤3：按照设计构建3D打印模型，将光固化树脂浆料按照3D打印模型打印即可得到支架坯体；步骤4：支架坯体经清洗、脱脂烧结即可得到所需支架；本发明能够制备兼具良好的力学性能、高效抗肿瘤能力及较好的促骨再生能力的双相生物活性组织修复支架，为临床上骨肿瘤术后骨缺损的修复提供技术支持。
Resumen de: CN120361299A
本发明公开了一种蛋白纳米纤维复合类血管及其制备方法与应用，属于3D打印类血管结构技术领域。本发明首先通过AF和GelMA的氢键相互作用，构建了含有纳米蛋白纤维的凝胶墨水，然后通过嵌入式3D打印方法，利用AF和HA的正负离子相互作用和基质相中引发剂向墨水相中的渗透作用，经过紫外光化学交联和后处理，构建了微观尺度上含有纳米蛋白纤维，宏观尺度上壁厚可调的类血管结构。该类血管结构微观尺度上可模拟细胞外基质微环境的纳米纤维结构，宏观尺度上可模拟人体不同部位血管的壁厚，为体外构建血管样结构提供了一种新策略。
Nº publicación: WO2025155025A1 24/07/2025
Solicitante:
OSSTEMIMPLANT CO LTD [KR]
\uC624\uC2A4\uD15C\uC784\uD50C\uB780\uD2B8 \uC8FC\uC2DD\uD68C\uC0AC
Resumen de: WO2025155025A1
Disclosed are a method, a device performing the method, and a recording medium, the method comprising the steps of: obtaining, by a processor, specification information about a plurality of standard pre-aligners, which is generated on the basis of statistical information; obtaining, by a reception unit, oral information about a user; determining, by the processor, one of the plurality of standard pre-aligners on the basis of the oral information and the specification information; obtaining, by the processor, a tooth model corresponding to the oral information; and deforming, by the processor, the determined standard pre-aligner to correspond to the tooth model so as to obtain a transparent orthodontic device corresponding to the tooth model.
BOPI
Sede Electrónica
