Bioimpresión 3D

一种用于治疗胫骨平台后内侧骨折的新型T-Y锁定支撑接骨板系统及其构建方法

Resumen de: CN122557118A

本申请公开了一种用于治疗胫骨平台后内侧骨折的新型T‑Y锁定支撑接骨板系统及其构建方法，涉及医疗器械领域，系统包括锁定支撑接骨板及若干锁定和普通螺钉；锁定支撑接骨板由依次连接并一体成型的近端T‑Y形头部、中间连接部和远端尾部组成，近端T‑Y形头部能够包裹胫骨平台后内侧髁，其近端T形头部贴合于胫骨平台内侧面，Y形分支部贴合平台后侧，所述中间连接部和远端尾部贴合于胫骨骨干内侧面；近端T形头部、Y形分支部与远端尾部分别设有锁定螺孔，中间连接部上设有锁定加压组合孔，所述锁定螺钉和普通螺钉分别匹配置入其中。本申请显著减少软组织剥离与植入物数量和体积，降低手术创伤、并发症发生率及后期再骨折风险。

一种用于促进腱骨愈合的梯度网格状补片及制备方法

Resumen de: CN122557814A

本申请涉及医用生物材料技术领域，具体而言，涉及一种用于促进腱骨愈合的梯度网格状补片及制备方法。所述补片为可吸收的网格状结构，具有沿第一方向相对设置的第一侧和第二侧，第一侧用于与骨组织贴合，第二侧用于与肌腱组织贴合；补片包括多个由纤维围合形成的网格单元，且网格单元的密度从第一侧向第二侧逐渐变化，补片为一体成型的单层结构，补片优选由I型胶原和II型胶原按特定质量比复合而成，并可沿第一方向梯度负载促成骨因子与促肌腱生成因子。本发明通过网格密度的空间渐变，实现了力学性能、降解行为和孔隙率的连续梯度分布，模拟天然腱‑骨界面的渐变微环境，引导细胞定向迁移与分化，促进肌腱‑纤维软骨‑骨的梯度组织再生。

一种个性化适配心肌软组织力学性能的仿生心肌电子补片及其制备方法

Resumen de: CN121796089A

The invention provides a bionic myocardial electronic patch for personalized adaptation of mechanical properties of myocardial soft tissue and a preparation method thereof, and relates to the field of regenerative medicine. The invention provides a bionic myocardial electronic patch adapted to mechanical properties of myocardial soft tissue in a personalized manner. The bionic myocardial electronic patch comprises a telescopic flexible fiber electrode, a tissue engineering fiber scaffold deposited on the surface of the telescopic flexible fiber electrode, a gold-plated nano layer on the surface of the fiber electrode and a PDMS passivation layer. After the bionic myocardial electronic patch provided by the invention is compounded and inoculated with hydrogel of myocardial cells differentiated from human pluripotent stem cells, nondestructive monitoring and transmission of electrical stimulation are realized, and meanwhile, the mechanical property of the myocardial tissue can be adjusted and adapted by the mechanical property of the tissue engineering fiber scaffold. The bionic myocardial electronic patch provided by the invention integrates the flexible electrode and the fiber scaffold, and can meet the biomechanical properties of monitoring, stimulating and adapting to myocardium at the same time.

一种基于电子束增材制造的椎间融合器尺寸补偿与变形控制方法

Resumen de: CN122557243A

本发明公开了一种基于电子束增材制造的椎间融合器尺寸补偿及变形控制方法，包括融合器主体所述融合器主体内部为三区梯度孔隙结构，所述三区梯度孔隙结构由内向外依次包括核心区、过渡区和骨整合区；本发明通过获得梯度孔隙结构以缓解应力遮挡、促进骨长入的同时，有效抵消了因孔隙率差异导致的热积累变形，解决了现有电子束增材制造融合器中整体尺寸公差和器械持取孔精度的问题。

一种舌侧保持器及其制作方法

Resumen de: CN122557206A

一种舌侧保持器及其制作方法，所述舌侧保持器包括与牙齿舌面贴合的舌板，相邻舌板之间通过连接杆连接为一个整体；上颌切牙及尖牙对应的舌板的舌侧面设有咬合导板，尖牙位置的咬合导板外表面与尖牙牙尖唇侧切端1/4处贴合设有尖牙定位导板，用于舌侧保持器的转移及定位；通过一体化结构提供高强度支撑，咬合导板可主动引导上下牙列的接触，建立稳定的咬合关系；同时，通过尖牙定位导板实现舌侧保持器精准快速粘接，以及网格底面保障长期固位，共同构成一套高效、稳定、个性化的正畸保持解决方案，尤其适用于高复发风险的深覆合与下颌后缩患者；具有临床效率提升、复发率降低、患者体验优化及适应症拓展等特点，具有显著的实用价值与推广前景。

Mucus analysis for animal health assessments

Resumen de: AU2026208120A1

The present teachings generally include techniques for characterizing the health of an animal (e.g., gastrointestinal health) using image analysis (e.g., of a sample of an exudate such as mucus) as a complement, alternative, or a replacement to traditional laboratory analyses of biological specimens. The present teachings may further include techniques for personalizing a health and wellness plan (including, but not limited to, a dietary supplement such as a customized formula based on a health assessment), where such a plan may be based on one or more of the health characterization techniques described herein. The present teachings may also or instead include techniques or plans for continuous care for an animal, e.g., by executing health characterization and heath planning techniques in a cyclical fashion. A personalized supplement system (e.g., using a personalized supplement, personalized dosing device, and personalized packaging) may also or instead be created using the present teachings. ul u l

SYSTEMS AND METHODS FOR ANALYSING ELECTROCARDIOGRAMS USING DEEP LEARNING

Resumen de: AU2025224889A1

Provided is a system and method for detecting cardiac abnormalities from electrocardiogram (ECG) data. The system provides an automated ECG platform comprised of standard medical equipment and modules for data acquisition, processing, analysis, interpretation, and a user interface, which can be integrated into existing clinical contexts. The method includes receiving ECG data from a patient, analyzing the data using a trained convolutional neural network (CNN) model to detect predetermined cardiac conditions, and generating an output indicating the presence of these conditions. The CNN model is developed through a deep learning process that includes collecting ECG-echocardiogram pairs from multiple patients, curating the collected data, training the CNN model with the curated data, validating model performance, testing model generalization, and generating diagnostic predictions with confidence scores.

ARTIFICIAL INTELLIGENCE-BASED SYSTEMS AND METHODS FOR AUTOMATIC MEASUREMENTS FOR PRE-PROCEDURAL PLANNING

Resumen de: US20260232382A1

0000 A computer implemented method to automatically measure structural features of anatomies using an automatic measurement system, the method includes receiving medical images of the anatomies. The method includes detecting landmarks of the anatomies based on the medical images using an artificial intelligence (AI)-based model and constructing an anatomical structural model of the anatomies based on the detected landmarks. The method includes making quantifying measurements of selected structural features of the anatomical structural model and generating a report including the quantifying measurements.

METHODS AND DEVICES FOR SECURE COMMUNICATION WITH AND OPERATION OF AN IMPLANT

Resumen de: US20260237380A1

A method of teaching a voice-controlled medical implant to recognize a voice command, the method comprising: inputting a first audio training phrase to the medical implant, when the medical implant is implanted in the body of the patient, creating a transfer function, the transfer function being based on the first audio training phrase, wherein the transfer function is configured to adjust the amplitude of at least one frequency of audio received at the medical device for enhancing audio received at the medical implant to facilitate detection of voice commands, inputting a second audio training phrase to the medical implant, the second audio training phrase comprising the voice command, the voice command comprising an instruction for the control of the medical implant, using the transfer function for generating an enhanced second audio training phrase in the medical implant, and associating the enhanced second audio training phrase with the instruction for the control of the medical implant.

APPARATUS AND METHOD FOR AUTOMATIC ULTRASOUND SEGMENTATION FOR VISUALIZATION AND MEASUREMENT

Resumen de: US20260232296A1

A system and method for performing ultrasound scans is provided. One embodiment of the ultrasonographic system acquires sonogram information from a series of ultrasonic scans of a human subject. The series of ultrasound scans are taken over a portion of interest on the human subject which has their underlying bone structure or other ultrasound discernable organ that is under examination. The data from the series of scans are synthesized into a single data file that corresponds to a three-dimensional (3D) image and/or 3D model of the underlying bone structure or organ of the examined human subject.

INTERVERTEBRAL CAGE WITH INTEGRATED TRANSMITTER

Resumen de: US20260237475A1

0000 A medical implant can comprise a physical structure configured to secure the medical implant within a body of a patient, a proximity communication component physically coupled to the physical structure, and a memory operatively coupled to the proximity communication component. The memory can store a private key, wherein the memory is configured to provide the private key through the proximity communication component to an external device for enabling the external device to access one or more electronic medical records associated with a patient that is implanted with the implant from a distributed blockchain ledger of electronic medical records.

Patient Ventilator Asynchrony Detection

Resumen de: US20260237511A1

A decision support tool is provided for identifying and assisting clinicians with patient ventilator asynchrony. The information used to make the identification may include data from a patient's ventilator including the volume, flow, and pressure associated with that ventilator. At least some of this information may be used to compute one or more features for a time series of the data received for the patient. These features may be used in connection with heuristic rules and machine learning algorithms to identify instances of patient ventilator asynchrony. Based on the identification, one or more intervening actions may be initiated to reduce the impact of patient ventilator asynchrony.

SUCTION DEVICE AND INFORMATION PROCESSING METHOD

Resumen de: US20260232930A1

0000 Provided is a suction device provided with: a housing section having an inner space and an opening; a first detection unit which detects the state of the inner space; a second detection unit which detects information associated with the state of the suction device; and a control unit that performs, on the basis of a detection result obtained by the second detection unit, the control of the switching of the mode of the first detection unit to an operation mode or a stop mode and the determination whether or not the control of the operation of the suction device is performed in accordance with a detection value detected by the first detection unit when the mode of the first detection unit is in the operation mode.

DEVICES, SYSTEMS, AND METHODS FOR VIRTUAL STAINING

Resumen de: US20260232197A1

0000 The disclosure herein provides methods, systems, and devices for virtually staining biological tissue for enhanced visualization without use of an actual dye or tag by detecting how each pixel of an unstained tissue image changes in waveform after staining with a certain dye(s) and/or tag(s) or other transformation under a certain electromagnetic radiation source, developing a virtual staining transform based on such detection, and applying such virtual staining transform to an unstained biological tissue to virtually stain the tissue.

INTERVERTEBRAL FUSION CAGE WITH BIOMIMETIC TRABECULAR BONE AND FULLY POROUS STRUCTURE MANUFACTURED BY ADDITIVE MANUFACTURING

Resumen de: US20260232457A1

An intervertebral fusion cage with a biomimetic trabecular bone and fully porous structure manufactured by additive manufacturing is applied in spinal fusion surgery, made of medical metal and manufactured by selective laser melting or electron beam melting. The intervertebral fusion cage includes: a front end surface, a rear end surface, a first side surface, a second side surface, an upper fusion surface and a lower fusion surface. The upper fusion surface and the lower fusion surface are configured for being in direct contact with vertebral endplates of a spine, and provided with anti-slip teeth. A center of the intervertebral fusion cage defines a bone graft window penetrating through the upper fusion surface and the lower fusion surface. The intervertebral fusion cage has a structure and mechanical properties similar to those of human cancellous bone and trabecular bone, and can increase the bone contact area and bone ingrowth space.

UNIVERSAL METHOD FOR CREATING A CUSTOMIZED OBSTRUCTIVE SLEEP APNEA PREVENTION APPLIANCE

Resumen de: US20260232482A1

An obstructive sleep apnea (OSA) prevention appliance can be made according to a common path but customized for a user using at least a 3D oral scan taken with a first imaging modality and a 3D reconstruction formed with a plurality of images taken with a second imaging modality different from the first imaging modality. The 3D oral scan and the 3D reconstruction can be aligned and registered together for use in creating a customized model of the OSA prevention appliance. The model can be created by orienting and positioning two model cylinders with respect to aspects of the user's mouth anatomy, forming a model of a mouthguard based on the model cylinders and the anatomy, and modeling a wire configured to hold at least a portion of the tongue from collapsing during sleep. The model can be used to produce the OSA prevention appliance for the user.

SURGICAL INSTRUMENT PORT FOR VAGINAL NATURAL ORIFICE TRANSLUMINAL ENDOSCOPIC SURGERY

Resumen de: US20260232352A1

A surgical instrument port is designed for use in vaginal natural orifice transluminal endoscopic surgery, made of a disposable, biocompatible and elastic material, and allows multiple surgical instruments and endoscopes to simultaneously have access to the desired body cavity.

Information Management System and Method

Resumen de: US20260237501A1

A computer-implemented method, computer program product and computing system for: interfacing with a bedside monitoring device to receive data signals, wherein the data signals have monitoring criteria; enabling adjustment of one or more of the monitoring criteria; suggesting a proposed change to a user concerning the one or more monitoring criteria; and providing feedback to the user concerning the proposed change.

COMPOSITIONS AND METHODS FOR THREE-DIMENSIONAL (3D) BIOPRINTING

Resumen de: US20260232869A1

0000 As a three-dimensional (3D) bioprinting technique, digital light processing (DLP) has become popular due to its capability to provide high-throughput and high-resolution constructs with precise chemical and biological factor distributions. However, despite the advancements in DLP technology, several hurdles remain, including phototoxicity, extensive printing time, and the limited portfolio of biocompatible/photo-cross-Jinkable materials. Herein, a novel DLP-based 3D-bioprinting technology′ called photopolymerization of orderly-extruded multi-materials (POEM) has been developed and fully characterized. The utility of the POEM technique for rapid and high-resolution 3D-printing of multi-material, multi-layer, and cell-laden structures is demonstrated. The printed configurations showed high cell viability (−80%) and metabolic activity′ for more than five days. The light-based POEM technique described herein enables the fabrication of 3D-cell-laden structures in a multi-material and multi-layer printing manner in biocompatible/photo-cross-linkable materials essential to construct complex heterogeneous tissues/organs.

VASCULAR GRAFT ASSEMBLIES, VASCULAR GRAFT SYSTEMS, AND METHODS OF USE THEREOF

Resumen de: US20260232426A1

Reinforced external graft support assemblies and methods of manufacture and implantation are provided herein. In particular, graft support assemblies are composed of single or multilayer sheaths designed to provide mechanical support to vascular conduits during cardiovascular bypass surgery. Graft sheath systems may be fabricated using 3D printing techniques with biocompatible materials incorporate surgical design considerations such as mechanical strength, flexibility, porosity, and the ability to be tailored to specific anatomical structures. External graft sheaths may include one or more layers of various biomaterials to produce customized biomechanical properties including varied time courses of degradation. Furthermore, these customizable features may incorporate standardized designs or be tailored for individual patients depending on medical and surgical history, or other pertinent geometric attributes measured in pre-operative medical imaging. These methods protect vascular conduits, particularly venous grafts, from adverse remodeling and graft failure, thereby providing precision medicine solutions to cardiovascular bypass surgery.

GENERATION OF ARTIFICIAL INTRA-OPERATIVE SENSOR DATA

Resumen de: US20260232380A1

0000 A computer-implemented method of generating artificial intra-operative sensor data usable in training an artificial intelligence (AI) module is presented. The method comprises the following steps: providing a clinical data structure describing several clinical states of a clinical procedure and defining transitions between said several clinical states allowing for different paths of the clinical procedure (step S1); providing at least one geometrical model for modelling procedural scenes in one or more of said clinical states of said clinical procedure (step S2), wherein the at least one geometrical model comprises a plurality of geometrical model parameters and boundary conditions for said geometrical model parameters; wherein the geometrical model parameters describe said procedural scenes in said clinical states of said clinical procedure, wherein a particular combination of values of the geometrical model parameters defines a particular procedural scene of a clinical state of said clinical procedure; the method further comprising the steps defining an individual path of the clinical procedure by selecting at least one transition between a first and a second clinical state of the clinical data structure (step S3); providing, as input for the geometrical model, a set of values of the geometrical model parameters of the at least one geometrical model for said first and said second clinical states of the defined individual path thereby modelling a first individual pro

TECHNIQUES FOR AUTOMATED MARKING OF DENTAL APPLIANCES

Resumen de: US20260233338A1

The present disclosure discusses techniques for marking a dental appliance. A dental model and dental appliance are positioned onto a conveyor tray, which is transported to a scan station. The dental model and conveyor tray each include an identifying code. The scan station includes a camera and barcode reader to read the identifying codes on the dental model and conveyor tray, and these codes are associated with one another. The conveyor tray then moves to a marking station where a barcode reader reads the code on the conveyor tray, and then marks the dental appliance with the appropriate marking.

TECHNIQUES FOR IDENTIFYING REPRESENTATIVE PPG PULSES

Resumen de: US20260232212A1

0000 Methods, systems, and devices for identifying representative photoplethysmogram (PPG) pulses are described. A method may include acquiring a first set of PPG pulses from a user via a wearable device. The method may include comparing a set of morphological features of the first set of PPG pulses, and determining one or more PPG profiles for the user, where the one or more PPG profiles each include a set of morphological value ranges for the set of morphological features. The method may include acquiring a second set of PPG pulses from the user via the wearable device, and determining that one or more PPG pulses from the second set of PPG pulses match the one or more PPG profiles. The method may include determining one or more physiological metrics associated with the user based on the one or more PPG pulses matching the one or more PPG profiles.

DENTAL IMAGING SYSTEM AND METHOD

Resumen de: US20260232411A1

A dental imaging system for capturing images of a patient's arches and teeth includes a central processor for storing images, a camera having a camera lens and a camera housing, and a camera holder having a tray, an angled column extending from a front of the tray and an engagement mechanism positioned at a distal end of the angled column. The engagement mechanism is configured to releasably engage the camera to orient the camera lens toward the patient's arches and teeth.

Acute Stressors Detection Using a Wearable Device

Nº publicación: US20260237521A1 13/08/2026

Solicitante:

ZEPP INC [US]
ANHUI HUAMI HEALTH TECH CO LTD [CN]
Zepp, Inc.
Anhui Huami Health Technology Co., Ltd.

Resumen de: US20260237521A1

0000 A method of acute stressor detection using a wearable device includes obtaining sensor data for an individual from one or more sensors of the wearable device while the wearable device is worn, the sensor data including physiological data. A processor determines one or more physiological parameters, including one or more heart rate related parameters, from the sensor data and determines data associated with at least one lifestyle event, including a sleep event or an exercise event. The processor detects a physiological deviation event indicative of reduced adaptive capacity based on the one or more physiological parameters, determines at least one candidate acute stressor for the physiological deviation event based on the lifestyle-event data and data associated with the physiological deviation event, and outputs an indication of the at least one candidate acute stressor to the individual.