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168
resultados
Última actualización
27/01/2026 [07:14:00]
Resultados 25 a 50 de 168
Resumen de: EP4389180A1
The present invention provides a nebuliser (100) comprising one or more inputs (110), and a plurality of droplet ejectors (126) in fluid communication with the one or more inputs (110). Each droplet ejector comprises a nozzle portion and a piezoelectric actuator. The one or more inputs are for receiving one or more liquids. Each nozzle portion defines a nozzle outlet in fluid communication with the one or more inputs. Each piezoelectric actuator is operable to cause ejection of a liquid received by one of the one or more inputs through the respective nozzle outlet as one or more droplets to thereby generate an aerosol comprising the one or more droplets ejected by each droplet ejector.
Resumen de: WO2024189111A1
The present invention relates to a mixture, for 3D printing, particularly a resin for 3D printing comprising - a monomer, oligomer or polymer, or a mixture thereof, comprising at least one acrylate or methacrylate subunit, and - a lactam, characterized in that the lactam concentration is 0.001 to 0.3 wt%, particularly the lactam concentration is 0.001 to 0.15 wt%, more particularly the lactam concentration is 0.01 to 0.1 wt%. Furthermore, the present invention relates to a polymer, in particular a dental polymer or an otoplastic polymer comprising polymerised monomers and/or oligomers or polymers and a lactam, as well as a medical product comprising said polymer.
Resumen de: KR20240084787A
The present invention relates to a system for manufacturing artificial organs based on big data. the system for manufacturing artificial organs according to the present invention comprises: an input unit for receiving a user's requirement for artificial organs to be manufactured as an input value; a database unit for storing data necessary for manufacturing artificial organs; a control unit for manufacturing artificial organs by inputting the input value to an artificial organ manufacturing algorithm learned based on the database unit; and a bio printer for manufacturing artificial organs according to the control of the control unit.
Resumen de: CN121038767A
The present disclosure provides crosslinker compounds that can produce desired polymeric materials, polymeric compositions, and/or photocurable resins. Further provided herein are methods of producing crosslinker compounds, compositions, resins, devices, and polymeric materials. Also provided herein are methods of making (e.g., by 3D printing) a medical device (e.g., an orthodontic appliance) using a crosslinker compound, a resin, and a polymeric material.
Resumen de: WO2024191748A2
A curable composition includes a urethane (meth) acrylate monomer and an acidic or latent acidic comonomer. The urethane (meth) acrylate monomer includes 2 to 12 urethane groups and, independently, 2 to 12 (meth)acrylate groups, wherein each of at least two urethane groups is separated from at least one other urethane group or at least one urea group by at most three carbon atoms. The urethane (meth) acrylate monomer has a molecular weight less than or equal to 5,000 grams/mole. In the curable composition, the molar ratio of urethane groups in the urethane (meth) acrylate monomer to carboxylic acid and carboxylic acid anhydride groups in the acidic or latent acidic comonomer is 1:3 to 3:1.
Resumen de: CN120936704A
Three-dimensional (3D) bioprinted cell culture systems of tumor tissue, methods of making and methods of using the same are described. The 3D cell culture system provides a plurality of compartments and vasculature as well as cell interfaces, including a tumor/non-tumor interface, a tumor-vasculature interface, to reconstruct a tumor immune microenvironment. The hardness of the 3D bio-printed stent can be adjusted to reflect different stages of canceration, including fibrosis, cirrhosis and fatty degeneration; and establishing chemical gradients, such as oxygen levels, to simulate oxidation pressure and hypoxic conditions. The manufacture of 3D cell cultures is achieved by bioprinting, such as micro-forming, injection exclusion, and suspension bioprinting techniques.
Resumen de: AU2024235637A1
A surgical clamp for providing a stable mechanical grasp and stabilisation of bone during an orthopaedic surgical procedure, comprising: a first arm comprising: an extended section comprising a mount at the distal end thereof; and a first jaw portion located at the distal end of the first arm; a second arm comprising: a fastening platform located at the proximal end of the second arm; and a second jaw portion located at the distal end of the second arm; engagement means comprising a bolt to engage the first arm with the second arm about a pivot point formed by the engagement means to provide relative rotation of the first and second arms between: an open configuration whereby first jaw portion and second jaw portion are urged apart; and a clamped configuration whereby first jaw portion and second jaw portion are urged into clamping engagement with the patient's bone in use during the surgical procedure; a fastening component comprising a fastening bolt and a fastening nut, adapted to engage the first and second arm into a locked clamped configuration about the bone of a patient during the surgical procedure; and a handle adapted to be gripped by a surgical assistance for stabilisation of the patient's joint or bone during the surgical procedure.
Resumen de: US2025128021A1
Systems and methods for altering the geometry of a fluid channel to prevent upstream mobility of bacteria, using angled obstacles on the interior of the channel that among other things creates vortices that restrict the mobility. An optimized geometry can be realized by an artificial intelligence algorithm or similar methods based on performance of various configurations of obstacle parameters.
Resumen de: US2024400859A1
The present disclosure provides a miktoarm polymer having the following structure:where polymer chain 1, 2, 3, 4, A1 and A2 are as defined herein. These miktoarm polymers can produce desirable polymeric materials and being used as a component in photo-curable resins. Further provided herein are methods of producing miktoarm polymers, as well as compositions, resins, devices, and polymeric materials by use of the same. Also provided herein are methods of using miktoarm polymers, resins, and polymeric materials for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.
Resumen de: CN121360286A
本发明属于3D打印材料技术领域，具体公开了一种具有主动收缩功能的智能水凝胶及制备方法与应用，制备方法包括以下步骤：S1、将3‑丙烯酰胺基苯硼酸加入去离子水中，得到3‑丙烯酰胺基苯硼酸溶液；S2、将单宁酸加入3‑丙烯酰胺基苯硼酸溶液中，得到单宁酸3‑丙烯酰胺基苯硼酸溶液；S3、将苯基‑2,4,6‑三甲基苯甲酰基次膦酸锂、瓜尔豆胶依次加入单宁酸3‑丙烯酰胺基苯硼酸溶液中，得到具有主动收缩功能的智能水凝胶。本发明采用上述一种具有主动收缩功能的智能水凝胶及制备方法与应用，解决现有挤出式3D打印技术中成型精度与结构分辨率不足的问题，为毛细血管网络、神经微导管等精细组织的体外仿生构建提供了新的技术路径。
Resumen de: CN121360284A
本发明涉及一种兼具抑菌和抗氧化功能的聚谷氨酸生物墨水及其制备方法与应用。该方法首先将高分子量γ‑聚谷氨酸在特定高温下降解，获得低粘度、适于打印的降解γ‑聚谷氨酸（dγ‑PGA）；然后将其与甲基丙烯酸酰化试剂反应，制得可光交联的甲基丙烯酰化降解γ‑聚谷氨酸（dγ‑PGAGMA）；最后将dγ‑PGAGMA、光引发剂与活细胞混合，即得所述生物墨水。本发明不仅适合3D生物打印可以任意成型，打印成型的水凝胶能兼具抑制细菌存活和具有抗氧化的功效，能促进软骨细胞的生长和软骨组织的再生。
Resumen de: CN121360283A
本发明公开了一种面部植入填充材料及其制备方法，涉及医用材料技术领域；所述面部植入填充材料由3D纤维基复合型微球、凝胶基体组成；将3D纤维基复合型微球深入缠绕、互锁在凝胶基体中，呈现高度均匀分散性，从而更加有效地传递应力，提高了材料的机械强度，有利于抵抗植入后变形，两者构建的仿生复合结构通过抵抗降解、维持体积和促进组织长入的方式，实现主动的组织再生与替代，显著提升了填充作用的有效性和长效性。
Resumen de: CN121338088A
本发明涉及牙种植体领域，具体涉及一种亲骨牙种植体及其制备方法，包括以下步骤：步骤1、将亲骨活性生物陶瓷、磷酸锶和β‑甘油磷酸镁混合在钽金属粉末中，获得混合原料；步骤2、将所述混合原料经过3D打印，获得种植体基体；步骤3、在所述种植体基体上生成聚多巴胺涂层，获得涂层种植体；步骤4、将水凝胶粘接在所述涂层种植体上，获得亲骨牙种植体。本发明的聚多巴胺涂层一方面通过邻苯二酚基团与钽金属粉末形成共价键，通过醌基与锶/镁离子螯合。另一方面，聚多巴胺涂层的酚羟基与水凝胶极性基团形成氢键网络，还与水凝胶存在阳离子‑π作用和疏水协同。因此，水凝胶能够通过聚多巴胺涂层与种植体基体间接牢固地粘接在一起。
Resumen de: CN121338090A
本发明公开一种多级孔结构钛基生物活性骨植入复合材料的制备方法，属于生物医用材料技术领域。本方法将TC4钛合金粉末、ZrO2粉末、羟基磷灰石粉末及NaCl粉末按一定比例混合后，与多组分粘结剂体系密炼造粒，通过3D打印工艺制备生坯；生坯经温水和草酸催化脱脂后，在氩气保护下进行阶梯式热脱脂和低温预烧结‑高温致密化烧结，制备多级孔结构钛基生物活性骨植入复合材料。本发明制备的复合材料具有独特的三级贯通孔隙结构：由3D打印填充路径间隙产生的毫米级孔隙、NaCl造孔剂水脱去除后遗留的亚毫米级孔隙和HA与基体热膨胀系数差异生成的微米级孔隙，该复合材料力学性能与结构仿生设计均符合人体骨组织的适配性要求。
Resumen de: CN121358688A
一种超结构玻璃碳及其制备方法和应用，首先提供了一种具有各向应力均匀分布的稳定结构的超结构玻璃碳，其次还提供了这种超结构玻璃碳的制备方法、应用，以及基于这种超结构玻璃碳得到的骨修复材料。
Resumen de: WO2024145635A2
Root-analog dental implants include one or more coronal grooves that are sized, shaped, and/or configured to correspond to a size, shape, and/or position of a bone crest for an extracted tooth a root-analog dental implant is designed and manufactured to replace. The coronal grooves may be configured to engage with bone of an alveolar socket to enhance engagement between the root-analog dental implant and the alveolar socket particularly for the time period following seating the root-analog dental implant within the socket site and prior to osseointegration of the root-analog dental implant with the alveolar socket. This promotes stability of the root-analog dental implant within the socket site immediately following insertion and thereafter, which may decrease movement of the root-analog dental implant within the socket site, decrease a likelihood of foreign material such as bacteria or food entering the socket site, and/or reduce a risk of implant failure and jawbone injury.
Resumen de: CN121337888A
本发明公开了一种基于FLYZ的3D打印吞咽友好型凝胶及其制备方法，制备方法包括如下步骤：S1、将茯苓、杏仁、陈皮按质量比（2‑5）：1：（2.5‑5）加水进行提取；S2、将食用胶和核桃油分散在步骤S1获得的提取液，并在60‑70℃下搅拌至完全水合，冷却后得到油墨；S3、将步骤S2得到的油墨用3D打印机打印为基于FLYZ的3D打印吞咽友好型凝胶。本发明通过凝胶组分配比与工艺参数控制，获得既具有显著抗氧化活性又满足吞咽困难者（IDDSI 4级/极浓稠—糊状）口感与安全性的3D打印凝胶，实现可重复、可调的硬度、黏附性等质构指标，满足吞咽困难人群对口腔停留与易下咽的要求。
Resumen de: US2025009476A1
The present disclosure provides polymeric materials comprising semicrystalline sulfur-containing polymers, methods and curable compositions for making the same, and orthodontic appliances made from said polymeric materials.
Resumen de: CN121338092A
本发明属于3D打印技术领域，公开了一种实现聚合物增韧陶瓷基骨支架的增材制造方法，采用炭黑油墨作为陶瓷油墨挤出细丝的内芯，打印坯体经干燥及烧结去除炭黑组分，形成具有粗糙内壁的中空的细丝孔，将坯体浸入加热的石蜡中，仅填充挤出细丝的丝间隙而不进入细丝孔，为聚合物填充预留通道，坯体被置于聚合物单体溶液中，聚合物单体通过毛细作用进入细丝孔并固化，以超过石蜡熔点小于聚合物熔点的温度加热坯体去除石蜡，得到聚合物增韧陶瓷基骨支架。有效规避聚合物在热处理过程中的熔化或降解风险，确保细丝孔内聚合物的完整，保障骨支架在生物环境中的力学稳定性与长期增韧效果。聚合物逐渐分解，有利于细胞的生长及新陈代谢的物质运输。
Resumen de: CN121338091A
本申请涉及生物医用材料技术领域，具体公开了一种双交联3D打印骨修复支架的制备方法。该支架由双相磷酸钙基体与明胶甲基丙烯酰化物水凝胶外层复合制成。其制备方法为：首先制备双相磷酸钙墨水，通过3D打印构建多孔支架坯体；接着依次进行氯化钙溶液和戊二醛溶液的双重交联处理，得到力学性能增强的支架基体；然后制备负载经修饰的特立帕肽的明胶甲基丙烯酰化物水凝胶，并将其与支架基体复合，经蓝光交联固化后获得最终产品。本申请的骨修复支架具有良好的生物相容性和成骨活性，可有效促进骨缺损修复。另外，本申请的制备方法工艺可控、重复性好，通过3D打印技术实现了支架结构的精准调控，为个性化骨修复材料的制备提供了新途径。
Resumen de: CN121337589A
本发明提出基于3D打印技术的力度传感刮痧板，包括以3D打印方式制备的刮痧头，还包括含握持部的刮痧板壳体，刮痧头、握持部之间以燕尾榫结构体、插销连接为可更换刮痧头的分体式结构，所述刮痧板壳体处设有与信息转化模块相连的压力传感器；所述握持部与信息记录模块紧邻；当刮痧头刮痧端对受术用户刮痧施力时，刮痧头的壳体端与压力传感器接触，信息转化模块经压力传感器采集刮痧头壳体端受力数据，并将受力数据送至信息记录模块；本发明采用3D打印成形的刮痧头，并在刮痧头与壳体结合部嵌入压力传感器，实时采集压力数据并通过随机森林回归模型预测最佳舒适度区间，能突破传统刮痧操作的主观性局限。
Resumen de: WO2026014565A1
Disclosed is a method for manufacturing a surgical hemostatic clip. The method for manufacturing a surgical hemostatic clip comprises: a 3D printing step of producing, through a 3D printing process, a surgical hemostatic clip including a pair of legs that are arranged to face each other so as to form an overall U-shape and have a polygonal cross-sectional shape, and a plurality of vascular pressing projections protruding from mutually facing inner surfaces of the pair of legs; a burr-removal step of removing burrs adhering to the edges or surfaces of the pair of legs and the plurality of vascular pressing projections; a heat-treatment step of heat-treating the deburred surgical hemostatic clip at a temperature of 500°C to 1000°C for 24 hours or more; and a surface-treatment step of heating the entire surface of the surgical hemostatic clip (100) to 450°C or higher by using an oxygen-propane flame to form a titanium oxide TiO2 layer, subsequently polishing the surface of the surgical hemostatic clip using at least one of Al2O3, V2O5, and SiO2 powders, and then polishing the surface of the surgical hemostatic clip using 50,000-mesh diamond powder.
Resumen de: WO2026015744A1
Disclosed herein is a lingual mandibular distractor and methods and systems for designing the same. The lingual mandibular distractor as disclosed herein is configured to be installed at a lingual surface of the mouth of a patient. The lingual mandibular distractor as disclosed herein is designed based on the intended patient's specific anatomy. 3D printing processes may be utilized to create the frame of the lingual mandibular distractor, and an expansion assembly is connected to the frame to complete the lingual mandibular distractor appliance.
Resumen de: WO2026015085A1
There is provided a composite structure for promoting wound healing, the structure comprising, a compressible substrate; and a bioactive material disposed on said compressible substrate, wherein the bioactive material comprises a mixture of a synthetic homopolymer and a bioactive copolymer.
Nº publicación: US20260013770A1 15/01/2026
Solicitante:
CB INNOVATIONS LLC [US]
CB Innovations, LLC
Resumen de: US20260013770A1
An emergency cardiac and electrocardiogram (ECG) electrode placement device is disclosed herein. The emergency cardiac and electrocardiogram (ECG) electrode placement device incorporates electrical conducting materials and elastic material into a pad that is applied to a chest wall of a patient, which places multiple electrodes in the appropriate anatomic locations on the patient to quickly obtain an ECG in a pre-hospital setting.
BOPI
Sede Electrónica
